trimethyloxamine has been researched along with Inborn Errors of Metabolism in 20 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The fish odour syndrome was diagnosed in 11 subjects: the percentage of total trimethylamine excreted in their urine samples that was oxidised to trimethylamine N-oxide was < 55% under normal dietary conditions and < 25% after oral challenge with trimethylamine (in normal subjects > 80% of trimethylamine was N-oxidised)." | 5.07 | The fish odour syndrome: biochemical, familial, and clinical aspects. ( Ayesh, R; Mitchell, SC; Smith, RL; Zhang, A, 1993) |
| "An oral trimethylamine challenge test has been used to confirm the heterozygous status of patients with 'fish-odour syndrome'." | 3.69 | Fish odour syndrome: verification of carrier detection test. ( Mitchell, S; Smith, R; Zhang, AQ, 1995) |
| " Beginning with a single propositus, who had been previously diagnosed at the age of 10 as suffering from trimethylaminuria (fish-odour syndrome), both her parents and two sisters were investigated biochemically with respect to their ability to N-oxidize trimethylamine (TMA), both when derived from the diet and when administered exogenously." | 3.67 | Trimethylaminuria ('fish-odour syndrome'): a study of an affected family. ( Al-Waiz, M; Ayesh, R; Idle, JR; Mitchell, SC; Smith, RL, 1988) |
| "Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour." | 2.53 | The complex metabolism of trimethylamine in humans: endogenous and exogenous sources. ( Bhargava, B; Chhibber-Goel, J; Gaur, A; Parakh, N; Sharma, A; Singhal, V, 2016) |
| "Trimethylamine (TMA) is a volatile substance produced in the gut, absorbed into the blood and further metabolized by healthy individuals into trimethylamine-N-oxide (TMAO) by TMA-oxidase and then excreted in urine." | 1.33 | Diagnosis of suspected trimethylaminuria by NMR spectroscopy. ( Arêas, JA; Lanfer-Marquez, UM; Podadera, P; Sipahi, AM, 2005) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (10.00) | 18.7374 |
| 1990's | 7 (35.00) | 18.2507 |
| 2000's | 5 (25.00) | 29.6817 |
| 2010's | 4 (20.00) | 24.3611 |
| 2020's | 2 (10.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fadhlaoui, K | 1 |
| Arnal, ME | 1 |
| Martineau, M | 1 |
| Camponova, P | 1 |
| Ollivier, B | 1 |
| O'Toole, PW | 1 |
| Brugère, JF | 1 |
| Veyrat-Durebex, C | 1 |
| Benz-de-Bretagne, I | 1 |
| Clavier, V | 1 |
| Bruno, C | 1 |
| Andres, CR | 1 |
| Antar, C | 1 |
| Hennart, B | 1 |
| Maillot, F | 1 |
| Nadal-Desbarats, L | 1 |
| Blasco, H | 1 |
| Gao, C | 1 |
| Catucci, G | 1 |
| Castrignanò, S | 1 |
| Gilardi, G | 1 |
| Sadeghi, SJ | 1 |
| D'Angelo, R | 1 |
| Scimone, C | 1 |
| Esposito, T | 1 |
| Bruschetta, D | 1 |
| Rinaldi, C | 1 |
| Ruggeri, A | 1 |
| Sidoti, A | 1 |
| Oliveira, A | 1 |
| Faria, A | 1 |
| Oliva, M | 1 |
| Chhibber-Goel, J | 1 |
| Gaur, A | 1 |
| Singhal, V | 1 |
| Parakh, N | 1 |
| Bhargava, B | 1 |
| Sharma, A | 1 |
| Fraser-Andrews, EA | 1 |
| Manning, NJ | 1 |
| Ashton, GH | 1 |
| Eldridge, P | 1 |
| McGrath, J | 1 |
| Menagé, Hdu P | 1 |
| Yamazaki, H | 1 |
| Fujieda, M | 1 |
| Togashi, M | 1 |
| Saito, T | 1 |
| Preti, G | 1 |
| Cashman, JR | 1 |
| Kamataki, T | 1 |
| Podadera, P | 1 |
| Sipahi, AM | 1 |
| Arêas, JA | 1 |
| Lanfer-Marquez, UM | 1 |
| Hsu, WY | 1 |
| Lo, WY | 1 |
| Lai, CC | 1 |
| Tsai, FJ | 1 |
| Tsai, CH | 1 |
| Tsai, Y | 1 |
| Lin, WD | 1 |
| Chao, MC | 1 |
| Johnson, DW | 1 |
| Hadidi, HF | 1 |
| Cholerton, S | 1 |
| Atkinson, S | 1 |
| Irshaid, YM | 1 |
| Rawashdeh, NM | 1 |
| Idle, JR | 3 |
| Ayesh, R | 3 |
| Mitchell, SC | 4 |
| Zhang, A | 1 |
| Smith, RL | 4 |
| Zhang, AQ | 2 |
| Mitchell, S | 1 |
| Smith, R | 1 |
| Maschke, S | 1 |
| Wahl, A | 1 |
| Azaroual, N | 1 |
| Boulet, O | 1 |
| Crunelle, V | 1 |
| Imbenotte, M | 1 |
| Foulard, M | 1 |
| Vermeersch, G | 1 |
| Lhermitte, M | 1 |
| Thithapandha, A | 1 |
| Mamer, OA | 1 |
| Choinière, L | 1 |
| Treacy, EP | 1 |
| al-Waiz, M | 2 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study to Evaluate Oral Chlorophyllin in Hemorrhagic Cystitis Secondary to Radiation Therapy for Pelvic Malignancies[NCT05348239] | Phase 2 | 24 participants (Anticipated) | Interventional | 2022-03-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for trimethyloxamine and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Archaea, specific genetic traits, and development of improved bacterial live biotherapeutic products: another face of next-generation probiotics.
Topics: Animals; Archaea; Biological Therapy; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Hu | 2020 |
The complex metabolism of trimethylamine in humans: endogenous and exogenous sources.
Topics: Air Pollutants; Animals; Atherosclerosis; Diet; Humans; Metabolism, Inborn Errors; Methylamines; Neo | 2016 |
2 trials available for trimethyloxamine and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Effects of the dietary supplements, activated charcoal and copper chlorophyllin, on urinary excretion of trimethylamine in Japanese trimethylaminuria patients.
Topics: Adult; Charcoal; Chlorophyllides; Diet; Dietary Supplements; Drug Therapy, Combination; Female; Huma | 2004 |
The fish odour syndrome: biochemical, familial, and clinical aspects.
Topics: Adolescent; Adult; Animals; Female; Fishes; Humans; Infant; Male; Mental Disorders; Metabolism, Inbo | 1993 |
16 other studies available for trimethyloxamine and Inborn Errors of Metabolism
| Article | Year |
|---|---|
Quality consideration for the validation of urine TMA and TMAO measurement by nuclear magnetic resonance spectroscopy in Fish Odor Syndrome.
Topics: Calibration; Female; Humans; Magnetic Resonance Spectroscopy; Metabolism, Inborn Errors; Methylamine | 2021 |
Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine.
Topics: Computer Simulation; Humans; In Vitro Techniques; Metabolism, Inborn Errors; Methylamines; Mutation; | 2017 |
Fish odor syndrome (trimethylaminuria) supporting the possible FMO3 down expression in childhood: a case report.
Topics: Biomarkers; Child; Down-Regulation; Female; Genetic Markers; Humans; Metabolism, Inborn Errors; Meth | 2014 |
Fish Malodour syndrome in a child.
Topics: Child, Preschool; Diagnosis, Differential; Diet Therapy; Female; Humans; Hygiene; Metabolism, Inborn | 2015 |
Fish odour syndrome with features of both primary and secondary trimethylaminuria.
Topics: Biomarkers; Female; Humans; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants | 2003 |
Diagnosis of suspected trimethylaminuria by NMR spectroscopy.
Topics: Adult; Amines; Animals; Choline; Diet; Dogfish; Humans; Magnetic Resonance Spectroscopy; Male; Metab | 2005 |
Rapid screening assay of trimethylaminuria in urine with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Child, Preschool; Female; Humans; Infant; Metabolism, Inborn Errors; Methylamines; Reproducibility o | 2007 |
A flow injection electrospray ionization tandem mass spectrometric method for the simultaneous measurement of trimethylamine and trimethylamine N-oxide in urine.
Topics: Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Spectrometry, Mass, Electrospray Ionizati | 2008 |
The N-oxidation of trimethylamine in a Jordanian population.
Topics: Adult; Ethnicity; Female; Humans; Jordan; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged | 1995 |
Fish odour syndrome: verification of carrier detection test.
Topics: Adult; Female; Genetic Carrier Screening; Humans; Male; Metabolism, Inborn Errors; Methylamines; Odo | 1995 |
Discontinuous distribution of N-oxidation of dietary-derived trimethylamine in a British population.
Topics: Adult; Diet; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants; O | 1996 |
1H-NMR analysis of trimethylamine in urine for the diagnosis of fish-odour syndrome.
Topics: Amine Oxidase (Copper-Containing); Female; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Met | 1997 |
A pharmacogenetic study of trimethylaminuria in Orientals.
Topics: Adult; Asian People; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odo | 1997 |
Measurement of trimethylamine and trimethylamine N-oxide independently in urine by fast atom bombardment mass spectrometry.
Topics: Case-Control Studies; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Reference Value | 1999 |
Trimethylaminuria: the detection of carriers using a trimethylamine load test.
Topics: Administration, Oral; Adult; Genetic Carrier Screening; Humans; Male; Metabolism, Inborn Errors; Met | 1989 |
Trimethylaminuria ('fish-odour syndrome'): a study of an affected family.
Topics: Adult; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Syndrome | 1988 |