trimethyloxamine has been researched along with Disease Exacerbation in 21 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients, is both elevated in the circulation of patients having heart failure and heralds worse overall prognosis." | 7.83 | Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure. ( Bhushan, S; Bradley, J; Hazen, SL; Lefer, DJ; Organ, CL; Otsuka, H; Polhemus, DJ; Tang, WH; Trivedi, R; Wang, Z; Wu, Y, 2016) |
| "Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients, is both elevated in the circulation of patients having heart failure and heralds worse overall prognosis." | 3.83 | Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure. ( Bhushan, S; Bradley, J; Hazen, SL; Lefer, DJ; Organ, CL; Otsuka, H; Polhemus, DJ; Tang, WH; Trivedi, R; Wang, Z; Wu, Y, 2016) |
| "Inflammation is the key for the initiation and progression of atherosclerosis." | 2.66 | Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis. ( Chen, YH; Kao, HL; Liu, SF; Wu, MS; Wu, WK; Yang, KC; Yeh, CF, 2020) |
| "However, its role in nonalcoholic steatohepatitis (NASH) is unknown." | 1.51 | Trimethylamine N-oxide attenuates high-fat high-cholesterol diet-induced steatohepatitis by reducing hepatic cholesterol overload in rats. ( Fan, JG; Liu, XL; Pan, Q; Xin, FZ; Xue, YQ; Yang, RX; Zhao, ZH; Zhou, D, 2019) |
| "Atherosclerosis is a multifactorial and progressive disease commonly correlated with a high fat diet." | 1.40 | Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy. ( Guo, J; Li, J; Li, X; Liu, Y; Wang, L; Wu, T; Yang, Y; Yuan, F; Zhang, Q; Zheng, L, 2014) |
| "Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in precursors to TMA, such as trimethylamine-N-oxide (TMNO), choline and L-carnitine." | 1.33 | Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis. ( Bain, MA; Evans, AM; Faull, R; Fornasini, G; Milne, RW, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 15 (71.43) | 24.3611 |
| 2020's | 5 (23.81) | 2.80 |
| Authors | Studies |
|---|---|
| Calderón-Pérez, L | 1 |
| Suárez-García, S | 1 |
| Pedret, A | 1 |
| Suárez, M | 1 |
| Llauradó, E | 1 |
| Rubió, L | 1 |
| Del Bas, JM | 1 |
| Caimari, A | 1 |
| Puiggrós, F | 1 |
| Arola, L | 1 |
| Solà, R | 1 |
| Valls, RM | 1 |
| Matsuzawa, Y | 1 |
| Nakahashi, H | 1 |
| Konishi, M | 1 |
| Sato, R | 1 |
| Kawashima, C | 1 |
| Kikuchi, S | 1 |
| Akiyama, E | 1 |
| Iwahashi, N | 1 |
| Maejima, N | 1 |
| Okada, K | 1 |
| Ebina, T | 1 |
| Hibi, K | 1 |
| Kosuge, M | 1 |
| Ishigami, T | 1 |
| Tamura, K | 1 |
| Kimura, K | 1 |
| Tan, Y | 1 |
| Zhou, J | 1 |
| Liu, C | 1 |
| Zhou, P | 1 |
| Sheng, Z | 1 |
| Li, J | 3 |
| Chen, R | 1 |
| Song, L | 1 |
| Zhao, H | 1 |
| Xu, B | 1 |
| Gao, R | 1 |
| Yan, H | 1 |
| Ravid, JD | 1 |
| Chitalia, VC | 1 |
| Yeh, CF | 1 |
| Chen, YH | 1 |
| Liu, SF | 1 |
| Kao, HL | 1 |
| Wu, MS | 1 |
| Yang, KC | 1 |
| Wu, WK | 1 |
| Taguchi, K | 1 |
| Fukami, K | 1 |
| Elias, BC | 1 |
| Brooks, CR | 1 |
| Geng, J | 1 |
| Yang, C | 1 |
| Wang, B | 1 |
| Zhang, X | 1 |
| Hu, T | 1 |
| Gu, Y | 1 |
| Yu, L | 1 |
| Meng, G | 1 |
| Huang, B | 1 |
| Zhou, X | 1 |
| Stavrakis, S | 1 |
| Wang, M | 2 |
| Li, X | 2 |
| Zhou, L | 1 |
| Wang, Y | 1 |
| Wang, Z | 2 |
| Deng, J | 1 |
| Po, SS | 1 |
| Jiang, H | 1 |
| Suzuki, T | 1 |
| Yazaki, Y | 1 |
| Voors, AA | 1 |
| Jones, DJL | 1 |
| Chan, DCS | 1 |
| Anker, SD | 1 |
| Cleland, JG | 1 |
| Dickstein, K | 1 |
| Filippatos, G | 1 |
| Hillege, HL | 1 |
| Lang, CC | 1 |
| Ponikowski, P | 1 |
| Samani, NJ | 1 |
| van Veldhuisen, DJ | 1 |
| Zannad, F | 1 |
| Zwinderman, AH | 1 |
| Metra, M | 1 |
| Ng, LL | 1 |
| Chioncel, O | 1 |
| Ambrosy, AP | 1 |
| Polsinelli, VB | 1 |
| Marteau, L | 1 |
| Shah, SJ | 1 |
| El-Deeb, OS | 1 |
| Atef, MM | 1 |
| Hafez, YM | 1 |
| Zhao, ZH | 1 |
| Xin, FZ | 1 |
| Zhou, D | 1 |
| Xue, YQ | 1 |
| Liu, XL | 1 |
| Yang, RX | 1 |
| Pan, Q | 1 |
| Fan, JG | 1 |
| Loureiro, CC | 1 |
| Duarte, IF | 1 |
| Gomes, J | 1 |
| Carrola, J | 1 |
| Barros, AS | 1 |
| Gil, AM | 1 |
| Bousquet, J | 1 |
| Bom, AT | 1 |
| Rocha, SM | 1 |
| Yang, Y | 1 |
| Liu, Y | 1 |
| Zheng, L | 2 |
| Wu, T | 1 |
| Zhang, Q | 1 |
| Yuan, F | 1 |
| Wang, L | 1 |
| Guo, J | 1 |
| Collins, HL | 1 |
| Drazul-Schrader, D | 1 |
| Sulpizio, AC | 1 |
| Koster, PD | 1 |
| Williamson, Y | 1 |
| Adelman, SJ | 1 |
| Owen, K | 1 |
| Sanli, T | 1 |
| Bellamine, A | 1 |
| Organ, CL | 1 |
| Otsuka, H | 1 |
| Bhushan, S | 1 |
| Bradley, J | 1 |
| Trivedi, R | 1 |
| Polhemus, DJ | 1 |
| Tang, WH | 1 |
| Wu, Y | 1 |
| Hazen, SL | 1 |
| Lefer, DJ | 1 |
| Robinson-Cohen, C | 1 |
| Newitt, R | 1 |
| Shen, DD | 1 |
| Rettie, AE | 1 |
| Kestenbaum, BR | 1 |
| Himmelfarb, J | 1 |
| Yeung, CK | 1 |
| Fu, Q | 1 |
| Zhao, M | 1 |
| Wang, D | 1 |
| Hu, H | 1 |
| Guo, C | 1 |
| Chen, W | 1 |
| Li, Q | 1 |
| Chen, B | 1 |
| Meyer, KA | 1 |
| Benton, TZ | 1 |
| Bennett, BJ | 1 |
| Jacobs, DR | 1 |
| Lloyd-Jones, DM | 1 |
| Gross, MD | 1 |
| Carr, JJ | 1 |
| Gordon-Larsen, P | 1 |
| Zeisel, SH | 1 |
| Bain, MA | 1 |
| Faull, R | 1 |
| Fornasini, G | 1 |
| Milne, RW | 1 |
| Evans, AM | 1 |
4 reviews available for trimethyloxamine and Disease Exacerbation
| Article | Year |
|---|---|
Molecular Mechanisms Underlying the Cardiovascular Toxicity of Specific Uremic Solutes.
Topics: Basic Helix-Loop-Helix Transcription Factors; Blood Platelets; Cardiovascular Diseases; Disease Prog | 2020 |
Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis.
Topics: Animals; Atherosclerosis; Clinical Trials as Topic; Cytokines; Disease Progression; Dysbiosis; Fatty | 2020 |
Dysbiosis-Related Advanced Glycation Endproducts and Trimethylamine N-Oxide in Chronic Kidney Disease.
Topics: Animals; Cardiovascular Diseases; Disease Progression; Dysbiosis; Gastrointestinal Microbiome; Glyca | 2021 |
The role of splanchnic congestion and the intestinal microenvironment in the pathogenesis of advanced heart failure.
Topics: Disease Progression; Enterocytes; Fatty Acids, Volatile; Gastrointestinal Microbiome; Heart Failure; | 2019 |
17 other studies available for trimethyloxamine and Disease Exacerbation
| Article | Year |
|---|---|
Serum lysophospholipidome of dietary origin as a suitable susceptibility/risk biomarker of human hypercholesterolemia: A cross-sectional study.
Topics: Animals; Biomarkers; Cholesterol, LDL; Cricetinae; Cross-Sectional Studies; Diet; Dietary Fats; Dise | 2022 |
Microbiota-derived Trimethylamine N-oxide Predicts Cardiovascular Risk After STEMI.
Topics: Aged; Biomarkers; Coronary Angiography; Disease Progression; Female; Follow-Up Studies; Gastrointest | 2019 |
Association Between Plasma Trimethylamine N-oxide and Neoatherosclerosis in Patients With Very Late Stent Thrombosis.
Topics: Atherosclerosis; Biomarkers; Coronary Vessels; Disease Progression; Drug-Eluting Stents; Female; Fol | 2020 |
Trimethylamine N-oxide promotes atherosclerosis via CD36-dependent MAPK/JNK pathway.
Topics: Animals; Apolipoproteins E; Atherosclerosis; CD36 Antigens; Cytokines; Disease Models, Animal; Disea | 2018 |
A potential relationship between gut microbes and atrial fibrillation: Trimethylamine N-oxide, a gut microbe-derived metabolite, facilitates the progression of atrial fibrillation.
Topics: Animals; Atrial Fibrillation; Disease Progression; Dogs; Gastrointestinal Microbiome; Heart Atria; I | 2018 |
Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure: results from BIOSTAT-CHF.
Topics: Biomarkers, Pharmacological; Disease Progression; Europe; Female; Heart Failure; Hospitalization; Hu | 2019 |
Trimethylamine N-oxide and risk of heart failure progression: marker or mediator of disease.
Topics: Biomarkers; Disease Progression; Heart Failure; Humans; Methylamines | 2019 |
The interplay between microbiota-dependent metabolite trimethylamine N-oxide, Transforming growth factor β/SMAD signaling and inflammasome activation in chronic kidney disease patients: A new mechanistic perspective.
Topics: Adult; Case-Control Studies; Disease Progression; Female; Humans; Interleukin-1beta; Male; Methylami | 2019 |
Trimethylamine N-oxide attenuates high-fat high-cholesterol diet-induced steatohepatitis by reducing hepatic cholesterol overload in rats.
Topics: Administration, Oral; Animals; Cholesterol, Dietary; Diet, High-Fat; Disease Models, Animal; Disease | 2019 |
Urinary metabolomic changes as a predictive biomarker of asthma exacerbation.
Topics: Adult; Aged; Asthma; Biomarkers; Carnitine; Cohort Studies; Disease Progression; Female; Gas Chromat | 2014 |
Serum metabonomic analysis of apoE(-/-) mice reveals progression axes for atherosclerosis based on NMR spectroscopy.
Topics: Animals; Atherosclerosis; Biomarkers; Cholesterol, HDL; Cholesterol, LDL; Choline; Diet, High-Fat; D | 2014 |
L-Carnitine intake and high trimethylamine N-oxide plasma levels correlate with low aortic lesions in ApoE(-/-) transgenic mice expressing CETP.
Topics: Animals; Apolipoproteins E; Atherosclerosis; Carnitine; Cells, Cultured; Cholesterol Ester Transfer | 2016 |
Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure.
Topics: Animals; Bacteria; Cardiomegaly; Choline; Diet; Disease Models, Animal; Disease Progression; Fibrosi | 2016 |
Association of FMO3 Variants and Trimethylamine N-Oxide Concentration, Disease Progression, and Mortality in CKD Patients.
Topics: Biomarkers; Disease Progression; Female; Humans; Male; Methylamines; Middle Aged; Oxygenases; Polymo | 2016 |
Coronary Plaque Characterization Assessed by Optical Coherence Tomography and Plasma Trimethylamine-N-oxide Levels in Patients With Coronary Artery Disease.
Topics: Biomarkers; Coronary Artery Disease; Disease Progression; Female; Humans; Male; Methylamines; Middle | 2016 |
Microbiota-Dependent Metabolite Trimethylamine N-Oxide and Coronary Artery Calcium in the Coronary Artery Risk Development in Young Adults Study (CARDIA).
Topics: Adult; Atherosclerosis; Black or African American; Carotid Intima-Media Thickness; Coronary Artery D | 2016 |
Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis.
Topics: Adult; Biomarkers; Case-Control Studies; Disease Progression; Female; Follow-Up Studies; Humans; Kid | 2006 |