Page last updated: 2024-10-20

trimethyloxamine and Disbacteriosis

trimethyloxamine has been researched along with Disbacteriosis in 44 studies

trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.

Research Excerpts

ExcerptRelevanceReference
" Gut dysbiosis increases with aging, and it has been associated with the impairment of gut barrier function leading to the leakage of harmful metabolites such as trimethylamine (TMA)."9.41The Role of the Gut Microbiome and Trimethylamine Oxide in Atherosclerosis and Age-Related Disease. ( Al-Arawe, N; El Hage, R; Hinterseher, I, 2023)
"Iron-overload leads to gut dysbiosis/inflammation and disturbance of metabolites, and deferiprone alleviates those conditions more effectively in WT than in those that are thalassemic."8.12Deferiprone has less benefits on gut microbiota and metabolites in high iron-diet induced iron overload thalassemic mice than in iron overload wild-type mice: A preclinical study. ( Buddhasiri, S; Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Kittichotirat, W; Kumfu, S; Nawara, W; Sarichai, P; Sriwichaiin, S; Thiennimitr, P; Thonusin, C, 2022)
"Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis."8.02Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021)
" Gut dysbiosis increases with aging, and it has been associated with the impairment of gut barrier function leading to the leakage of harmful metabolites such as trimethylamine (TMA)."5.41The Role of the Gut Microbiome and Trimethylamine Oxide in Atherosclerosis and Age-Related Disease. ( Al-Arawe, N; El Hage, R; Hinterseher, I, 2023)
"Iron-overload leads to gut dysbiosis/inflammation and disturbance of metabolites, and deferiprone alleviates those conditions more effectively in WT than in those that are thalassemic."4.12Deferiprone has less benefits on gut microbiota and metabolites in high iron-diet induced iron overload thalassemic mice than in iron overload wild-type mice: A preclinical study. ( Buddhasiri, S; Chattipakorn, N; Chattipakorn, SC; Fucharoen, S; Kittichotirat, W; Kumfu, S; Nawara, W; Sarichai, P; Sriwichaiin, S; Thiennimitr, P; Thonusin, C, 2022)
"Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis."4.02Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021)
"Trimethylamine-N-oxide (TMAO), a gut-microbiota-dependent metabolite generated from its dietary precursors such as choline, has been identified as an independent risk factor for atherosclerosis."4.02Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality. ( Du, Y; Hong, B; Li, X; Su, C; Wang, L; Yang, Y; Zhang, X, 2021)
"Choline is a water-soluble nutrient essential for human life."2.66The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases. ( Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A, 2020)
"Inflammation is the key for the initiation and progression of atherosclerosis."2.66Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis. ( Chen, YH; Kao, HL; Liu, SF; Wu, MS; Wu, WK; Yang, KC; Yeh, CF, 2020)
"Dysbiosis is associated with intestinal inflammation and reduced integrity of the gut barrier, which in turn increases circulating levels of bacterial structural components and microbial metabolites that may facilitate the development of CVD."2.58The gut microbiota as a novel regulator of cardiovascular function and disease. ( Battson, ML; Gentile, CL; Lee, DM; Weir, TL, 2018)
"Gut dysbiosis was associated with increased levels of TMAO, immature OCN-expressing EPCs, and CAD."1.62Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease. ( Ahmad, A; Corban, MT; Horwath, IE; Lerman, A; Lerman, LO; Loeffler, DL; Marietta, EV; Murray, JA; Ozcan, I; Sara, JD; Toya, T, 2021)
"Obesity is considered an important factor that increases the risk of colorectal cancer (CRC)."1.56Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer. ( Gómez-Millán, J; Laborda-Illanes, A; Medina, JA; Ordóñez, R; Otero, A; Plaza-Andrade, I; Queipo-Ortuño, MI; Ramos-Molina, B; Sánchez-Alcoholado, L, 2020)
"This dysbiosis was correlated with the severity of the disease."1.42Dysbiosis of Gut Microbiota With Reduced Trimethylamine-N-Oxide Level in Patients With Large-Artery Atherosclerotic Stroke or Transient Ischemic Attack. ( Chen, Q; He, Y; Liao, SX; Liu, FT; Pan, SY; Wang, S; Xia, GH; Yin, J; You, C; Zhou, HW; Zhou, L; Zhu, JJ, 2015)

Research

Studies (44)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's17 (38.64)24.3611
2020's27 (61.36)2.80

Authors

AuthorsStudies
Annunziata, G1
Ciampaglia, R1
Capò, X1
Guerra, F1
Sureda, A1
Tenore, GC1
Novellino, E1
Bin-Jumah, MN1
Gilani, SJ1
Hosawi, S1
Al-Abbasi, FA2
Zeyadi, M1
Imam, SS1
Alshehri, S1
Ghoneim, MM1
Nadeem, MS1
Kazmi, I1
Lanz, M1
Janeiro, MH1
Milagro, FI1
Puerta, E1
Ludwig, IA1
Pineda-Lucena, A1
Ramírez, MJ1
Solas, M1
Sriwichaiin, S1
Thiennimitr, P1
Thonusin, C1
Sarichai, P1
Buddhasiri, S1
Kumfu, S1
Nawara, W1
Kittichotirat, W1
Fucharoen, S1
Chattipakorn, N1
Chattipakorn, SC1
Schoch, L3
Sutelman, P3
Suades, R3
Badimon, L3
Moreno-Indias, I3
Vilahur, G3
El Hage, R1
Al-Arawe, N1
Hinterseher, I1
Hemmati, M1
Kashanipoor, S1
Mazaheri, P1
Alibabaei, F1
Babaeizad, A1
Asli, S1
Mohammadi, S1
Gorgin, AH1
Ghods, K1
Yousefi, B1
Eslami, M1
Craven, H1
Erlandsson, H1
McGuinness, D1
McGuinness, DH1
Mafra, D1
Ijaz, UZ1
Bergman, P2
Shiels, PG1
Stenvinkel, P2
Papa, A1
Santini, P1
De Lucia, SS1
Maresca, R1
Porfidia, A1
Pignatelli, P1
Gasbarrini, A1
Violi, F1
Pola, R1
Chan, MM1
Yang, X1
Wang, H2
Saaoud, F1
Sun, Y1
Fong, D1
Hardin, SJ1
Singh, M1
Eyob, W1
Molnar, JC1
Homme, RP1
George, AK1
Tyagi, SC1
Wang, J1
Gu, X1
Yang, J2
Wei, Y1
Zhao, Y1
Moludi, J1
Maleki, V1
Jafari-Vayghyan, H1
Vaghef-Mehrabany, E1
Alizadeh, M1
Koay, YC1
Chen, YC1
Wali, JA1
Luk, AWS1
Li, M1
Doma, H1
Reimark, R1
Zaldivia, MTK1
Habtom, HT1
Franks, AE1
Fusco-Allison, G1
Holmes, A1
Simpson, SJ1
Peter, K1
O'Sullivan, JF1
Zhang, B1
Wang, X1
Xia, R1
Li, C1
Arias, N1
Arboleya, S1
Allison, J1
Kaliszewska, A1
Higarza, SG1
Gueimonde, M1
Arias, JL1
Sánchez-Alcoholado, L1
Ordóñez, R1
Otero, A1
Plaza-Andrade, I1
Laborda-Illanes, A1
Medina, JA1
Ramos-Molina, B1
Gómez-Millán, J1
Queipo-Ortuño, MI1
Yeh, CF1
Chen, YH1
Liu, SF1
Kao, HL2
Wu, MS3
Yang, KC1
Wu, WK3
Naqvi, S1
Asar, TO1
Kumar, V1
Alhayyani, S1
Kamal, MA1
Anwar, F1
Zhao, J1
Ning, X1
Liu, B1
Dong, R1
Bai, M1
Sun, S1
Baragetti, A1
Severgnini, M1
Olmastroni, E1
Dioguardi, CC1
Mattavelli, E1
Angius, A1
Rotta, L1
Cibella, J1
Caredda, G1
Consolandi, C1
Grigore, L1
Pellegatta, F1
Giavarini, F1
Caruso, D1
Norata, GD1
Catapano, AL1
Peano, C1
Du, D1
Tang, W1
Zhou, C1
Sun, X1
Wei, Z1
Zhong, J1
Huang, Z1
Zhao, X1
Chen, Y1
Li, L2
Zhai, J1
Yu, B1
Yang, D1
Wang, Q1
Chang, Y1
Li, J2
Zhang, P1
Zhang, H1
Li, Y1
Toya, T1
Ozcan, I1
Corban, MT1
Sara, JD1
Marietta, EV1
Ahmad, A1
Horwath, IE1
Loeffler, DL1
Murray, JA1
Lerman, LO1
Lerman, A1
Li, X3
Su, C2
Jiang, Z1
Yang, Y2
Zhang, Y1
Yang, M1
Zhang, X2
Du, Y2
Zhang, J2
Wang, L2
Jiang, J1
Hong, B2
Taguchi, K1
Fukami, K1
Elias, BC1
Brooks, CR1
Yuzefpolskaya, M1
Bohn, B1
Javaid, A1
Mondellini, GM1
Braghieri, L1
Pinsino, A1
Onat, D1
Cagliostro, B1
Kim, A1
Takeda, K1
Naka, Y1
Farr, M1
Sayer, GT1
Uriel, N1
Nandakumar, R1
Mohan, S1
Colombo, PC1
Demmer, RT1
Xu, KY1
Xia, GH2
Lu, JQ1
Chen, MX1
Zhen, X1
Wang, S2
You, C2
Nie, J1
Zhou, HW2
Yin, J3
Cui, X1
Ye, L1
Jin, L1
Wang, W1
Li, S1
Bao, M1
Wu, S1
Geng, B1
Zhou, X2
Cai, J1
Leng, J1
Proudman, C1
Darby, A1
Blow, F1
Townsend, N1
Miller, A1
Swann, J1
Battson, ML1
Lee, DM1
Weir, TL1
Gentile, CL1
Li, DY1
Tang, WHW1
Missailidis, C1
Neogi, U1
Trøseid, M1
Nowak, P1
Bielinska, K1
Radkowski, M1
Grochowska, M1
Perlejewski, K1
Huc, T1
Jaworska, K1
Motooka, D1
Nakamura, S1
Ufnal, M1
Chen, CC1
Liu, PY1
Panyod, S1
Liao, BY1
Chen, PC1
Kuo, HC1
Kuo, CH1
Chiu, THT1
Chen, RA1
Chuang, HL1
Huang, YT1
Zou, HB1
Hsu, CC1
Chang, TY1
Lin, CL1
Ho, CT1
Yu, HT1
Sheen, LY2
Gong, J1
Noel, S1
Pluznick, JL1
Hamad, ARA1
Rabb, H1
Arduini, A1
Zammit, VA1
Bonomini, M1
Jin, M1
Qian, Z1
Xu, W1
Srinivasa, S1
Fitch, KV1
Lo, J1
Kadar, H1
Knight, R2
Wong, K1
Abbara, S1
Gauguier, D1
Capeau, J1
Boccara, F1
Grinspoon, SK1
Liao, SX1
He, Y1
Liu, FT1
Zhu, JJ1
Chen, Q1
Zhou, L1
Pan, SY1
Milani, C1
Ferrario, C1
Turroni, F1
Duranti, S1
Mangifesta, M1
van Sinderen, D1
Ventura, M1
Bergeron, N1
Williams, PT1
Lamendella, R1
Faghihnia, N1
Grube, A1
Wang, Z1
Jansson, JK1
Hazen, SL1
Krauss, RM1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Washed Microbiota Transplantation (WMT) for Chronic Kidney Disease (CKD): a Open Label, Multicenter Trial[NCT05838118]100 participants (Anticipated)Interventional2023-04-20Recruiting
Investigation on the Effect of Carnitine Supplement on Gut Microbiota and TMAO Production Capacity[NCT02838732]56 participants (Actual)Interventional2016-05-18Completed
Association Analysis of Cardiovascular and Nervous System Diseases and Intestinal Microbiome Based on Multi-omics Big Data and Related Applications[NCT06099496]490 participants (Anticipated)Observational [Patient Registry]2023-04-01Recruiting
A Randomised, Double-blinded, Cross-over, Placebo- Controlled Pilot Study to Investigate the Effect of Tomato Extract on TMAO in Overweight or Obese Adults[NCT04160481]37 participants (Actual)Interventional2019-11-12Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

18 reviews available for trimethyloxamine and Disbacteriosis

ArticleYear
Polycystic ovary syndrome and cardiovascular risk. Could trimethylamine N-oxide (TMAO) be a major player? A potential upgrade forward in the DOGMA theory.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 143

    Topics: Animals; Bacteria; Cardiovascular Diseases; Dysbiosis; Female; Gastrointestinal Microbiome; Heart Di

2021
Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients.
    Nutrients, 2021, Sep-29, Volume: 13, Issue:10

    Topics: Biodiversity; Biomarkers; Carnitine; Choline; Dietary Supplements; Disease Susceptibility; Dysbiosis

2021
The Role of the Gut Microbiome and Trimethylamine Oxide in Atherosclerosis and Age-Related Disease.
    International journal of molecular sciences, 2023, Jan-25, Volume: 24, Issue:3

    Topics: Aged; Aging; Animals; Atherosclerosis; Dysbiosis; Gastrointestinal Microbiome; Humans; Methylamines

2023
Importance of gut microbiota metabolites in the development of cardiovascular diseases (CVD).
    Life sciences, 2023, Sep-15, Volume: 329

    Topics: Atherosclerosis; Cardiovascular Diseases; Dysbiosis; Gastrointestinal Microbiome; Humans; Inflammati

2023
Gut dysbiosis-related thrombosis in inflammatory bowel disease: Potential disease mechanisms and emerging therapeutic strategies.
    Thrombosis research, 2023, Volume: 232

    Topics: Dysbiosis; Endotoxemia; Gastrointestinal Diseases; Humans; Inflammatory Bowel Diseases; Lipopolysacc

2023
The Microbial Metabolite Trimethylamine N-Oxide Links Vascular Dysfunctions and the Autoimmune Disease Rheumatoid Arthritis.
    Nutrients, 2019, Aug-07, Volume: 11, Issue:8

    Topics: Amyloid; Animals; Arthritis, Rheumatoid; Autoimmune Diseases; Cardiovascular Diseases; Diet; Dysbios

2019
Diet-induced chronic syndrome, metabolically transformed trimethylamine-N-oxide, and the cardiovascular functions.
    Reviews in cardiovascular medicine, 2019, Sep-30, Volume: 20, Issue:3

    Topics: Animals; Atherosclerosis; Bacteria; Diet, High-Fat; Dysbiosis; Endothelium, Vascular; Gastrointestin

2019
Metabolic endotoxemia and cardiovascular disease: A systematic review about potential roles of prebiotics and probiotics.
    Clinical and experimental pharmacology & physiology, 2020, Volume: 47, Issue:6

    Topics: Animals; Bacteria; Cardiovascular Diseases; Dysbiosis; Endotoxemia; Gastrointestinal Microbiome; Hea

2020
Gut microbiota in coronary artery disease: a friend or foe?
    Bioscience reports, 2020, 05-29, Volume: 40, Issue:5

    Topics: Animals; Bacteria; Coronary Artery Disease; Coronary Vessels; Dysbiosis; Gastrointestinal Microbiome

2020
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
    Nutrients, 2020, Aug-05, Volume: 12, Issue:8

    Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestina

2020
Mutual Interplay of Host Immune System and Gut Microbiota in the Immunopathology of Atherosclerosis.
    International journal of molecular sciences, 2020, Nov-19, Volume: 21, Issue:22

    Topics: Animals; Atherosclerosis; Clinical Trials as Topic; Cytokines; Disease Progression; Dysbiosis; Fatty

2020
A cross-talk between gut microbiome, salt and hypertension.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2021, Volume: 134

    Topics: Animals; Bacteria; Blood Pressure; Diet, Healthy; Diet, Sodium-Restricted; Dietary Fiber; Dietary Su

2021
Specific alterations in gut microbiota in patients with chronic kidney disease: an updated systematic review.
    Renal failure, 2021, Volume: 43, Issue:1

    Topics: Bacteria; Dysbiosis; Gastrointestinal Microbiome; Humans; Methylamines; Renal Insufficiency, Chronic

2021
Dysbiosis-Related Advanced Glycation Endproducts and Trimethylamine N-Oxide in Chronic Kidney Disease.
    Toxins, 2021, 05-19, Volume: 13, Issue:5

    Topics: Animals; Cardiovascular Diseases; Disease Progression; Dysbiosis; Gastrointestinal Microbiome; Glyca

2021
The gut microbiota as a novel regulator of cardiovascular function and disease.
    The Journal of nutritional biochemistry, 2018, Volume: 56

    Topics: Aging; Animals; Anti-Bacterial Agents; Atherosclerosis; Bile Acids and Salts; Cardiovascular Disease

2018
Contributory Role of Gut Microbiota and Their Metabolites Toward Cardiovascular Complications in Chronic Kidney Disease.
    Seminars in nephrology, 2018, Volume: 38, Issue:2

    Topics: Animals; Cardiovascular Diseases; Cresols; Diet Therapy; Dietary Supplements; Dysbiosis; Enzyme Inhi

2018
Gut Microbiota-Kidney Cross-Talk in Acute Kidney Injury.
    Seminars in nephrology, 2019, Volume: 39, Issue:1

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Dysbiosis; Fatty Acids, Volatile; Gastrointestinal Mic

2019
The role of intestinal microbiota in cardiovascular disease.
    Journal of cellular and molecular medicine, 2019, Volume: 23, Issue:4

    Topics: Bile Acids and Salts; Cardiovascular Diseases; Dysbiosis; Fatty Acids; Gastrointestinal Microbiome;

2019

Trials

3 trials available for trimethyloxamine and Disbacteriosis

ArticleYear
The gut microbiome dysbiosis is recovered by restoring a normal diet in hypercholesterolemic pigs.
    European journal of clinical investigation, 2023, Volume: 53, Issue:4

    Topics: Animals; Cholesterol; Diet; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Noncommunicable

2023
The gut microbiome dysbiosis is recovered by restoring a normal diet in hypercholesterolemic pigs.
    European journal of clinical investigation, 2023, Volume: 53, Issue:4

    Topics: Animals; Cholesterol; Diet; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Noncommunicable

2023
The gut microbiome dysbiosis is recovered by restoring a normal diet in hypercholesterolemic pigs.
    European journal of clinical investigation, 2023, Volume: 53, Issue:4

    Topics: Animals; Cholesterol; Diet; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Noncommunicable

2023
The gut microbiome dysbiosis is recovered by restoring a normal diet in hypercholesterolemic pigs.
    European journal of clinical investigation, 2023, Volume: 53, Issue:4

    Topics: Animals; Cholesterol; Diet; Diet, High-Fat; Dysbiosis; Gastrointestinal Microbiome; Noncommunicable

2023
Effect of DLT-SML on Chronic Stable Angina Through Ameliorating Inflammation, Correcting Dyslipidemia, and Regulating Gut Microbiota.
    Journal of cardiovascular pharmacology, 2021, 02-19, Volume: 77, Issue:4

    Topics: Adult; Aged; Angina, Stable; Anti-Inflammatory Agents; Bacteria; Biomarkers; China; Cytokines; Drug

2021
Diets high in resistant starch increase plasma levels of trimethylamine-N-oxide, a gut microbiome metabolite associated with CVD risk.
    The British journal of nutrition, 2016, Volume: 116, Issue:12

    Topics: Adult; Biomarkers; Body Mass Index; California; Cardiovascular Diseases; Cross-Over Studies; Diet, C

2016

Other Studies

23 other studies available for trimethyloxamine and Disbacteriosis

ArticleYear
Trimethylamine N-oxide (TMAO) drives insulin resistance and cognitive deficiencies in a senescence accelerated mouse model.
    Mechanisms of ageing and development, 2022, Volume: 204

    Topics: Animals; Cognition; Dementia; Disease Models, Animal; Dysbiosis; Gastrointestinal Microbiome; Insuli

2022
Deferiprone has less benefits on gut microbiota and metabolites in high iron-diet induced iron overload thalassemic mice than in iron overload wild-type mice: A preclinical study.
    Life sciences, 2022, Oct-15, Volume: 307

    Topics: Animals; Cytokines; Deferiprone; Diet; Dysbiosis; Gastrointestinal Microbiome; Inflammation; Iron; I

2022
A normative microbiome is not restored following kidney transplantation.
    Clinical science (London, England : 1979), 2023, 10-31, Volume: 137, Issue:20

    Topics: Dysbiosis; Gastrointestinal Microbiome; Humans; Kidney Transplantation; Microbiota; Renal Insufficie

2023
Gut Microbiota Dysbiosis and Increased Plasma LPS and TMAO Levels in Patients With Preeclampsia.
    Frontiers in cellular and infection microbiology, 2019, Volume: 9

    Topics: Adult; Biomarkers; Case-Control Studies; Dysbiosis; Feces; Female; Gastrointestinal Microbiome; Huma

2019
Plasma levels of trimethylamine-N-oxide can be increased with 'healthy' and 'unhealthy' diets and do not correlate with the extent of atherosclerosis but with plaque instability.
    Cardiovascular research, 2021, 01-21, Volume: 117, Issue:2

    Topics: Animal Feed; Animals; Atherosclerosis; Bacteria; Biomarkers; Carotid Artery Diseases; Choline; Coron

2021
Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer.
    International journal of molecular sciences, 2020, Sep-16, Volume: 21, Issue:18

    Topics: Aged; Bacteria; Biomarkers; Body Mass Index; Colorectal Neoplasms; Dysbiosis; Feces; Female; Gastroi

2020
Gut Microbiota Functional Dysbiosis Relates to Individual Diet in Subclinical Carotid Atherosclerosis.
    Nutrients, 2021, Jan-21, Volume: 13, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Bacteria; Carnitine; Carotid Artery Diseases; Choline; Diet; Dysbios

2021
Fecal Microbiota Transplantation Is a Promising Method to Restore Gut Microbiota Dysbiosis and Relieve Neurological Deficits after Traumatic Brain Injury.
    Oxidative medicine and cellular longevity, 2021, Volume: 2021

    Topics: Animals; Brain; Brain Injuries, Traumatic; Dysbiosis; Fecal Microbiota Transplantation; Gastrointest

2021
Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease.
    PloS one, 2021, Volume: 16, Issue:3

    Topics: AC133 Antigen; Adult; Aged; Antigens, CD34; Case-Control Studies; Cells, Cultured; Clostridiales; Co

2021
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
    NPJ biofilms and microbiomes, 2021, 04-16, Volume: 7, Issue:1

    Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility;

2021
Levels of Trimethylamine N-Oxide Remain Elevated Long Term After Left Ventricular Assist Device and Heart Transplantation and Are Independent From Measures of Inflammation and Gut Dysbiosis.
    Circulation. Heart failure, 2021, Volume: 14, Issue:6

    Topics: Aged; Aged, 80 and over; Dysbiosis; Female; Gastrointestinal Microbiome; Heart Failure; Heart Transp

2021
Metformin alleviates choline diet-induced TMAO elevation in C57BL/6J mice by influencing gut-microbiota composition and functionality.
    Nutrition & diabetes, 2021, 07-31, Volume: 11, Issue:1

    Topics: Akkermansia; Animals; Atherosclerosis; Bifidobacterium; Choline; Diabetes Mellitus, Type 2; Diet; Dy

2021
Impaired renal function and dysbiosis of gut microbiota contribute to increased trimethylamine-N-oxide in chronic kidney disease patients.
    Scientific reports, 2017, 05-03, Volume: 7, Issue:1

    Topics: Adult; Aged; Animals; Betaine; Carnitine; Case-Control Studies; Choline; Clostridiaceae; Dysbiosis;

2017
Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients.
    Scientific reports, 2018, 01-12, Volume: 8, Issue:1

    Topics: Adult; Aged; Bacteria; Butyrates; Dysbiosis; Female; Gastrointestinal Microbiome; Heart Failure; Hum

2018
Exploration of the Fecal Microbiota and Biomarker Discovery in Equine Grass Sickness.
    Journal of proteome research, 2018, 03-02, Volume: 17, Issue:3

    Topics: Acetylcarnitine; Animals; Bacteroidetes; Biomarkers; Clostridium botulinum; Cresols; Dysbiosis; Fece

2018
The microbial metabolite trimethylamine-N-oxide in association with inflammation and microbial dysregulation in three HIV cohorts at various disease stages.
    AIDS (London, England), 2018, 07-31, Volume: 32, Issue:12

    Topics: Adult; Aged; Bacterial Translocation; Cardiovascular Diseases; Cluster Analysis; DNA, Bacterial; DNA

2018
High salt intake increases plasma trimethylamine N-oxide (TMAO) concentration and produces gut dysbiosis in rats.
    Nutrition (Burbank, Los Angeles County, Calif.), 2018, Volume: 54

    Topics: Animals; Dysbiosis; Feces; Gastrointestinal Microbiome; Intestinal Diseases; Male; Methylamines; Rat

2018
Identification of TMAO-producer phenotype and host-diet-gut dysbiosis by carnitine challenge test in human and germ-free mice.
    Gut, 2019, Volume: 68, Issue:8

    Topics: Animals; Cardiovascular Diseases; Carnitine; Diet; Dysbiosis; Feeding Behavior; Gastrointestinal Mic

2019
Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful?
    Gut, 2020, Volume: 69, Issue:2

    Topics: Animals; Carnitine; Diet; Dysbiosis; Humans; Methylamines; Mice; Phenotype

2020
Response to the letter: Identification of trimethylamine N-oxide (TMAO)-producer phenotype is interesting, but is it helpful?
    Gut, 2020, Volume: 69, Issue:3

    Topics: Animals; Carnitine; Diet; Dysbiosis; Humans; Methylamines; Mice; Phenotype

2020
Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine.
    AIDS (London, England), 2015, Feb-20, Volume: 29, Issue:4

    Topics: Choline; Coronary Artery Disease; Dysbiosis; Female; HIV Infections; Humans; Intestinal Diseases; Ma

2015
Dysbiosis of Gut Microbiota With Reduced Trimethylamine-N-Oxide Level in Patients With Large-Artery Atherosclerotic Stroke or Transient Ischemic Attack.
    Journal of the American Heart Association, 2015, Nov-23, Volume: 4, Issue:11

    Topics: Aged; Aged, 80 and over; Asymptomatic Diseases; Bacteria; Carotid Artery Diseases; Case-Control Stud

2015
The human gut microbiota and its interactive connections to diet.
    Journal of human nutrition and dietetics : the official journal of the British Dietetic Association, 2016, Volume: 29, Issue:5

    Topics: Animals; Autoimmune Diseases; Bile Acids and Salts; Diet, Healthy; Diet, Western; Dysbiosis; Fatty A

2016