trimethyloxamine has been researched along with Diabetes Mellitus in 12 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Diabetes Mellitus: A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Nowadays, diabetic kidney disease (DKD) has become one of the most threatening to the end-stage renal diseases, and the early prevention of DKD is inevitable for Diabetes Mellitus (DM) patients." | 1.91 | Zuogui-Jiangtang-Yishen decoction prevents diabetic kidney disease: Intervene pyroptosis induced by trimethylamine n-oxide through the mROS-NLRP3 axis. ( Huang, JH; Hui, BP; Lin, QX; Liu, X; Liu, Z; Peng, YJ; Wang, Y; Xie, J; Yi, ZY; Yu, R; Zhang, SH; Zhao, D, 2023) |
| "This case-cohort study included Chronic Renal Insufficiency Cohort participants with baseline diabetes, estimated glomerular filtration rate <60 mL/min/1." | 1.91 | Association of urine and plasma ADMA with atherosclerotic risk in DKD cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study. ( Anderson, AH; Bhat, Z; Brown, J; Brunengraber, H; Charleston, J; Chen, J; Feldman, HI; He, J; Hostetter, TH; Hsu, CY; Ix, JH; Kimmel, PL; Mehta, R; Rao, P; Sapa, H; Schelling, JR; Schrauben, SJ; Seegmiller, JC; Shafi, T; Shlipak, MG; Townsend, R; Vasan, RS; Xie, D; Zhang, X, 2023) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 6 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, D | 1 |
| Lu, Y | 1 |
| Yuan, S | 1 |
| Cai, X | 1 |
| He, Y | 1 |
| Chen, J | 2 |
| Wu, Q | 1 |
| He, D | 1 |
| Fang, A | 1 |
| Bo, Y | 1 |
| Song, P | 1 |
| Bogaert, D | 1 |
| Tsilidis, K | 1 |
| Larsson, SC | 1 |
| Yu, H | 1 |
| Zhu, H | 1 |
| Theodoratou, E | 1 |
| Zhu, Y | 1 |
| Li, X | 2 |
| Sapa, H | 2 |
| Gutiérrez, OM | 1 |
| Shlipak, MG | 2 |
| Katz, R | 1 |
| Ix, JH | 2 |
| Sarnak, MJ | 1 |
| Cushman, M | 1 |
| Rhee, EP | 1 |
| Kimmel, PL | 2 |
| Vasan, RS | 2 |
| Schrauben, SJ | 2 |
| Feldman, HI | 2 |
| Seegmiller, JC | 2 |
| Brunengraber, H | 2 |
| Hostetter, TH | 2 |
| Schelling, JR | 2 |
| Huang, YL | 1 |
| Xiang, Q | 1 |
| Zou, JJ | 1 |
| Wu, Y | 1 |
| Yu, R | 2 |
| Yi, ZY | 1 |
| Peng, YJ | 1 |
| Hui, BP | 1 |
| Liu, Z | 1 |
| Lin, QX | 1 |
| Zhao, D | 1 |
| Wang, Y | 1 |
| Liu, X | 1 |
| Xie, J | 1 |
| Zhang, SH | 1 |
| Huang, JH | 1 |
| Xie, D | 1 |
| Zhang, X | 1 |
| Anderson, AH | 1 |
| Hsu, CY | 1 |
| Shafi, T | 1 |
| Mehta, R | 1 |
| Bhat, Z | 1 |
| Brown, J | 1 |
| Charleston, J | 1 |
| He, J | 1 |
| Rao, P | 1 |
| Townsend, R | 1 |
| Sun, T | 1 |
| Zhang, Y | 1 |
| Yin, J | 1 |
| Peng, X | 1 |
| Zhou, L | 1 |
| Huang, S | 1 |
| Wen, Y | 1 |
| Cao, B | 1 |
| Chen, L | 1 |
| Yang, W | 1 |
| Tan, A | 1 |
| Cheng, J | 1 |
| Liu, L | 1 |
| Oellgaard, J | 1 |
| Winther, SA | 1 |
| Hansen, TS | 1 |
| Rossing, P | 1 |
| von Scholten, BJ | 1 |
| Nowiński, A | 1 |
| Ufnal, M | 1 |
| Cash, JG | 1 |
| Konaniah, E | 1 |
| Hegde, N | 1 |
| Kuhel, DG | 1 |
| Watanabe, M | 1 |
| Romick-Rosendale, L | 1 |
| Hui, DY | 1 |
| Mueller, DM | 1 |
| Allenspach, M | 1 |
| Othman, A | 1 |
| Saely, CH | 1 |
| Muendlein, A | 1 |
| Vonbank, A | 1 |
| Drexel, H | 1 |
| von Eckardstein, A | 1 |
| Obeid, R | 1 |
| Awwad, HM | 1 |
| Rabagny, Y | 1 |
| Graeber, S | 1 |
| Herrmann, W | 1 |
| Geisel, J | 1 |
| Dambrova, M | 1 |
| Latkovskis, G | 1 |
| Kuka, J | 1 |
| Strele, I | 1 |
| Konrade, I | 1 |
| Grinberga, S | 1 |
| Hartmane, D | 1 |
| Pugovics, O | 1 |
| Erglis, A | 1 |
| Liepinsh, E | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946] | 45 participants (Anticipated) | Interventional | 2023-04-15 | Recruiting | |||
| Effect of 1 Year Vitamin D or D Plus B-vitamins on Bone Markers in Elderly People[NCT02586181] | 93 participants (Actual) | Interventional | 2009-08-31 | Completed | |||
| B-Vitamins and Polyneuropathy in Patients With Type 2 Diabetes[NCT02588898] | 212 participants (Actual) | Observational | 2009-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for trimethyloxamine and Diabetes Mellitus
| Article | Year |
|---|---|
Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis.
Topics: Cardiovascular Diseases; Diabetes Mellitus; Gastrointestinal Microbiome; Humans; Hypertension; Methy | 2022 |
Trimethylamine N-oxide (TMAO) as a New Potential Therapeutic Target for Insulin Resistance and Cancer.
Topics: Animals; Antineoplastic Agents; Diabetes Mellitus; Drug Delivery Systems; Gastrointestinal Microbiom | 2017 |
Trimethylamine N-oxide: A harmful, protective or diagnostic marker in lifestyle diseases?
Topics: Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Diet; Gastrointestinal Microbiome; Homeostas | 2018 |
9 other studies available for trimethyloxamine and Diabetes Mellitus
| Article | Year |
|---|---|
Association of Uremic Solutes With Cardiovascular Death in Diabetic Kidney Disease.
Topics: Arginine; Biomarkers; Cardiovascular Diseases; Diabetes Mellitus; Diabetic Nephropathies; Humans; Me | 2022 |
Zuogui Jiangtang Shuxin formula Ameliorates diabetic cardiomyopathy mice
Topics: Animals; Diabetes Mellitus; Diabetic Cardiomyopathies; Glycolipids; Mice; RNA, Ribosomal, 16S; Tande | 2023 |
Zuogui-Jiangtang-Yishen decoction prevents diabetic kidney disease: Intervene pyroptosis induced by trimethylamine n-oxide through the mROS-NLRP3 axis.
Topics: Animals; Chromatography, Liquid; Diabetes Mellitus; Diabetic Nephropathies; Drugs, Chinese Herbal; H | 2023 |
Association of urine and plasma ADMA with atherosclerotic risk in DKD cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study.
Topics: Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus; D | 2023 |
Association of Gut Microbiota-Dependent Metabolite Trimethylamine N-Oxide with First Ischemic Stroke.
Topics: Age Factors; Alcohol Drinking; Body Mass Index; Case-Control Studies; China; Chromatography, Liquid; | 2021 |
Therapeutic reduction of lysophospholipids in the digestive tract recapitulates the metabolic benefits of bariatric surgery and promotes diabetes remission.
Topics: Animals; Biphenyl Compounds; Diabetes Mellitus; Diet, High-Fat; Dietary Carbohydrates; Female; Gastr | 2018 |
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Cor | 2015 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Ga | 2016 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Ga | 2016 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Ga | 2016 |
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Ga | 2016 |
Diabetes is Associated with Higher Trimethylamine N-oxide Plasma Levels.
Topics: Age Factors; Aged; Animals; Body Mass Index; Cardiovascular Diseases; Carnitine; Diabetes Mellitus; | 2016 |