Page last updated: 2024-10-20

trimethyloxamine and Coronary Disease

trimethyloxamine has been researched along with Coronary Disease in 16 studies

trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.

Coronary Disease: An imbalance between myocardial functional requirements and the capacity of the CORONARY VESSELS to supply sufficient blood flow. It is a form of MYOCARDIAL ISCHEMIA (insufficient blood supply to the heart muscle) caused by a decreased capacity of the coronary vessels.

Research Excerpts

ExcerptRelevanceReference
"Riboflavin is a cofactor in TMAO synthesis."5.56Circulating trimethyllysine and risk of acute myocardial infarction in patients with suspected stable coronary heart disease. ( Berge, RK; Bjørnestad, EØ; Dhar, I; Løland, K; Nilsen, DWT; Nordrehaug, JE; Nygaard, E; Nygård, O; Olset, H; Pedersen, EKR; Svardal, A; Svingen, GFT; Tell, GS; Ueland, PM, 2020)
"Atherosclerotic coronary heart disease is a common cardiovascular disease with high morbidity and mortality."3.01Intestinal Flora Metabolite Trimethylamine Oxide Is Inextricably Linked to Coronary Heart Disease. ( Hu, H; Jing, L; Tian, H; Xiang, Q; Zhai, C; Zhang, H, 2023)
"Meta-analysis and dose-response analysis of hazard ratio data from prospective observational studies reporting on the association between TMAO plasma concentrations and the incidence of MACE in patients with CHD were conducted."2.66Trimethylamine-N-oxide has prognostic value in coronary heart disease: a meta-analysis and dose-response analysis. ( Liao, PD; Wang, L; Yao, ME; Zhao, XJ, 2020)
"Riboflavin is a cofactor in TMAO synthesis."1.56Circulating trimethyllysine and risk of acute myocardial infarction in patients with suspected stable coronary heart disease. ( Berge, RK; Bjørnestad, EØ; Dhar, I; Løland, K; Nilsen, DWT; Nordrehaug, JE; Nygaard, E; Nygård, O; Olset, H; Pedersen, EKR; Svardal, A; Svingen, GFT; Tell, GS; Ueland, PM, 2020)

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's5 (31.25)24.3611
2020's11 (68.75)2.80

Authors

AuthorsStudies
Liu, Y1
Zheng, G1
Jin, X1
Fan, T1
Chen, Z1
Sheng, X1
Zhou, P1
Zhao, XN1
Ma, YY1
Tang, TJ1
Wang, SS1
Wang, L2
Huang, JL1
Zhang, H1
Jing, L1
Zhai, C1
Xiang, Q1
Tian, H1
Hu, H1
Yao, ME1
Liao, PD1
Zhao, XJ1
Heidenreich, PA1
Mamic, P1
Heianza, Y1
Ma, W1
DiDonato, JA1
Sun, Q2
Rimm, EB2
Hu, FB2
Rexrode, KM1
Manson, JE1
Qi, L1
Bjørnestad, EØ1
Olset, H1
Dhar, I1
Løland, K1
Pedersen, EKR1
Svingen, GFT1
Svardal, A1
Berge, RK1
Ueland, PM1
Tell, GS1
Nilsen, DWT1
Nordrehaug, JE1
Nygaard, E1
Nygård, O1
Patanè, S1
Rodelo-Haad, C1
Pendon-Ruiz de Mier, MV1
Soriano, S1
Rodríguez, M1
Santamaria, R1
Amrein, ML1
Lopez-Ayala, P1
Walter, J1
Widmer, V1
Mueller, C1
Liu, G1
Li, J1
Li, Y1
Hu, Y1
Franke, AA1
Liang, L1
Chan, AT1
Mukamal, KJ1
Dong, Z1
Liang, Z1
Guo, M1
Hu, S1
Shen, Z1
Hai, X1
Kehrmann, J1
Menzel, J1
Saeedghalati, M1
Obeid, R1
Schulze, C1
Holzendorf, V1
Farahpour, F1
Reinsch, N1
Klein-Hitpass, L1
Streeck, H1
Hoffmann, D1
Buer, J1
Esser, S1
Yu, D1
Shu, XO1
Rivera, ES1
Zhang, X1
Cai, Q1
Calcutt, MW1
Xiang, YB1
Li, H1
Gao, YT1
Wang, TJ1
Zheng, W1
Mueller, DM1
Allenspach, M1
Othman, A1
Saely, CH1
Muendlein, A1
Vonbank, A1
Drexel, H1
von Eckardstein, A1
Knudsen, A1
Christensen, TE1
Thorsteinsson, K1
Ghotbi, AA1
Hasbak, P1
Lebech, AM1
Nielsen, SD1
Hov, JR1
Berge, R1
Ripa, RS1
Kjær, A1
Trøseid, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
A Prospective, Epidemiologic and Multicentre Trial to Determine the Cardiovascular Risk, New Cardiovascular Events and the Cardiovascular Diseases in HIV-infected Patients: 15 Year Follow up[NCT04330287]2,000 participants (Anticipated)Observational2020-05-11Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for trimethyloxamine and Coronary Disease

ArticleYear
Virtual screening analysis of natural flavonoids as trimethylamine (TMA)-lyase inhibitors for coronary heart disease.
    Journal of food biochemistry, 2022, Volume: 46, Issue:12

    Topics: Coronary Disease; Flavonoids; Hesperidin; Humans; Lyases; Molecular Docking Simulation

2022
Intestinal Flora Metabolite Trimethylamine Oxide Is Inextricably Linked to Coronary Heart Disease.
    Journal of cardiovascular pharmacology, 2023, 03-01, Volume: 81, Issue:3

    Topics: Biomarkers; Coronary Disease; Gastrointestinal Microbiome; Humans; Methylamines

2023
Trimethylamine-N-oxide has prognostic value in coronary heart disease: a meta-analysis and dose-response analysis.
    BMC cardiovascular disorders, 2020, 01-09, Volume: 20, Issue:1

    Topics: Aged; Aged, 80 and over; Biomarkers; Coronary Disease; Female; Humans; Incidence; Male; Methylamines

2020

Other Studies

13 other studies available for trimethyloxamine and Coronary Disease

ArticleYear
Influence of Gut Microbiota and Trimethylamine N-Oxide in Patients with Coronary Heart Disease.
    International heart journal, 2022, Jul-30, Volume: 63, Issue:4

    Topics: Coronary Disease; Gastrointestinal Microbiome; Humans; Methylamines; Microbiota; Phylogeny

2022
Is Our Diet Turning Our Gut Microbiome Against Us?
    Journal of the American College of Cardiology, 2020, 02-25, Volume: 75, Issue:7

    Topics: Coronary Disease; Diet; Gastrointestinal Microbiome; Humans; Methylamines

2020
Long-Term Changes in Gut Microbial Metabolite Trimethylamine N-Oxide and Coronary Heart Disease Risk.
    Journal of the American College of Cardiology, 2020, 02-25, Volume: 75, Issue:7

    Topics: Adult; Case-Control Studies; Coronary Disease; Diet, Healthy; Female; Gastrointestinal Microbiome; H

2020
Circulating trimethyllysine and risk of acute myocardial infarction in patients with suspected stable coronary heart disease.
    Journal of internal medicine, 2020, Volume: 288, Issue:4

    Topics: Aged; Biomarkers; Coronary Disease; Female; Heart Disease Risk Factors; Humans; Lysine; Male; Methyl

2020
Long-Term Changes in Gut Microbial Metabolite TMAO, CHD Risk, and its Complex Regulatory Network.
    Journal of the American College of Cardiology, 2020, 06-23, Volume: 75, Issue:24

    Topics: Coronary Disease; Gastrointestinal Microbiome; Humans; Methylamines

2020
Trimethylamine N-Oxide and Coronary Heart Disease: Should We Consider the Kidney Function?
    Journal of the American College of Cardiology, 2020, 06-23, Volume: 75, Issue:24

    Topics: Coronary Disease; Gastrointestinal Microbiome; Humans; Kidney; Methylamines

2020
Coronary Heart Disease and TMAO Concentrations.
    Journal of the American College of Cardiology, 2020, 06-23, Volume: 75, Issue:24

    Topics: Coronary Disease; Gastrointestinal Microbiome; Humans; Methylamines

2020
Gut microbiota-derived metabolites and risk of coronary artery disease: a prospective study among US men and women.
    The American journal of clinical nutrition, 2021, 07-01, Volume: 114, Issue:1

    Topics: 4-Butyrolactone; Adult; Case-Control Studies; Coronary Disease; Diet; Female; Gastrointestinal Micro

2021
The Association between Plasma Levels of Trimethylamine N-Oxide and the Risk of Coronary Heart Disease in Chinese Patients with or without Type 2 Diabetes Mellitus.
    Disease markers, 2018, Volume: 2018

    Topics: Aged; China; Coronary Disease; Creatine Kinase, MB Form; Diabetes Mellitus, Type 2; Female; Humans;

2018
Gut Microbiota in Human Immunodeficiency Virus-Infected Individuals Linked to Coronary Heart Disease.
    The Journal of infectious diseases, 2019, 01-09, Volume: 219, Issue:3

    Topics: Adult; Aged; Bacteroides; Biodiversity; Coronary Disease; Female; Gastrointestinal Microbiome; HIV I

2019
Urinary Levels of Trimethylamine-N-Oxide and Incident Coronary Heart Disease: A Prospective Investigation Among Urban Chinese Adults.
    Journal of the American Heart Association, 2019, 01-08, Volume: 8, Issue:1

    Topics: Adult; Aged; Biomarkers; Case-Control Studies; China; Coronary Disease; Female; Follow-Up Studies; H

2019
Plasma levels of trimethylamine-N-oxide are confounded by impaired kidney function and poor metabolic control.
    Atherosclerosis, 2015, Volume: 243, Issue:2

    Topics: Aged; Betaine; Biomarkers; Blood Glucose; Choline; Chromatography, Liquid; Coronary Angiography; Cor

2015
Microbiota-Dependent Marker TMAO is Not Associated With Decreased Myocardial Perfusion in Well-Treated HIV-Infected Patients as Assessed by 82Rubidium PET/CT.
    Journal of acquired immune deficiency syndromes (1999), 2016, 08-01, Volume: 72, Issue:4

    Topics: Biomarkers; Cardiovascular System; Coronary Disease; Cross-Sectional Studies; Female; Gastrointestin

2016