Page last updated: 2024-10-20

trimethyloxamine and Colorectal Neoplasms

trimethyloxamine has been researched along with Colorectal Neoplasms in 7 studies

trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.

Colorectal Neoplasms: Tumors or cancer of the COLON or the RECTUM or both. Risk factors for colorectal cancer include chronic ULCERATIVE COLITIS; FAMILIAL POLYPOSIS COLI; exposure to ASBESTOS; and irradiation of the CERVIX UTERI.

Research Excerpts

ExcerptRelevanceReference
"Among gut microbiota-derived metabolites, trimethylamine-N-oxide (TMAO) is receiving increased attention due to its possible role in the carcinogenesis of colorectal cancer (CRC)."9.12Emerging role of trimethylamine-N-oxide (TMAO) in colorectal cancer. ( Dalal, N; Jalandra, R; Khosla, A; Kumar, A; Sharma, M; Singh, R; Solanki, PR; Verma, D; Yadav, AK, 2021)
"Few studies have examined associations between plasma choline metabolites and risk of colorectal cancer."7.80Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study. ( Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Caudill, MA; Cheng, TY; Cushing-Haugen, KL; Green, R; Lane, DS; Malysheva, O; Miller, JW; Neuhouser, ML; Ulrich, CM; Xiao, L; Zheng, Y, 2014)
"Among gut microbiota-derived metabolites, trimethylamine-N-oxide (TMAO) is receiving increased attention due to its possible role in the carcinogenesis of colorectal cancer (CRC)."5.12Emerging role of trimethylamine-N-oxide (TMAO) in colorectal cancer. ( Dalal, N; Jalandra, R; Khosla, A; Kumar, A; Sharma, M; Singh, R; Solanki, PR; Verma, D; Yadav, AK, 2021)
"Few studies have examined associations between plasma choline metabolites and risk of colorectal cancer."3.80Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study. ( Bae, S; Bailey, LB; Beresford, SA; Brown, EC; Caudill, MA; Cheng, TY; Cushing-Haugen, KL; Green, R; Lane, DS; Malysheva, O; Miller, JW; Neuhouser, ML; Ulrich, CM; Xiao, L; Zheng, Y, 2014)
"Obesity is considered an important factor that increases the risk of colorectal cancer (CRC)."1.56Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer. ( Gómez-Millán, J; Laborda-Illanes, A; Medina, JA; Ordóñez, R; Otero, A; Plaza-Andrade, I; Queipo-Ortuño, MI; Ramos-Molina, B; Sánchez-Alcoholado, L, 2020)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (42.86)24.3611
2020's4 (57.14)2.80

Authors

AuthorsStudies
Jalandra, R1
Dalal, N1
Yadav, AK1
Verma, D1
Sharma, M1
Singh, R1
Khosla, A1
Kumar, A1
Solanki, PR1
Yang, S1
Dai, H1
Lu, Y1
Li, R1
Gao, C1
Pan, S1
Duizer, C1
de Zoete, MR1
Sánchez-Alcoholado, L1
Ordóñez, R1
Otero, A1
Plaza-Andrade, I1
Laborda-Illanes, A1
Medina, JA1
Ramos-Molina, B1
Gómez-Millán, J1
Queipo-Ortuño, MI1
Liu, X1
Liu, H1
Yuan, C1
Zhang, Y1
Wang, W1
Hu, S1
Liu, L1
Wang, Y1
Bae, S1
Ulrich, CM1
Neuhouser, ML1
Malysheva, O1
Bailey, LB1
Xiao, L1
Brown, EC1
Cushing-Haugen, KL1
Zheng, Y1
Cheng, TY1
Miller, JW1
Green, R1
Lane, DS1
Beresford, SA1
Caudill, MA1
Xu, R1
Wang, Q1
Li, L1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Impact of Diet and Gut Microbiota on Trimethylamine-N-oxide Production and Fate in Humans[NCT02558673]40 participants (Actual)Interventional2014-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for trimethyloxamine and Colorectal Neoplasms

ArticleYear
Emerging role of trimethylamine-N-oxide (TMAO) in colorectal cancer.
    Applied microbiology and biotechnology, 2021, Volume: 105, Issue:20

    Topics: Colorectal Neoplasms; Humans; Methylamines; Oxides

2021
The Role of Microbiota-Derived Metabolites in Colorectal Cancer.
    International journal of molecular sciences, 2023, Apr-28, Volume: 24, Issue:9

    Topics: Animals; Bacteria; Bile Acids and Salts; Colorectal Neoplasms; Fatty Acids, Volatile; Gastrointestin

2023

Other Studies

5 other studies available for trimethyloxamine and Colorectal Neoplasms

ArticleYear
Trimethylamine N-Oxide Promotes Cell Proliferation and Angiogenesis in Colorectal Cancer.
    Journal of immunology research, 2022, Volume: 2022

    Topics: Animals; Cell Proliferation; Colorectal Neoplasms; Methylamines; Mice; Neovascularization, Pathologi

2022
Gut Microbiota-Mediated Inflammation and Gut Permeability in Patients with Obesity and Colorectal Cancer.
    International journal of molecular sciences, 2020, Sep-16, Volume: 21, Issue:18

    Topics: Aged; Bacteria; Biomarkers; Body Mass Index; Colorectal Neoplasms; Dysbiosis; Feces; Female; Gastroi

2020
Preoperative serum TMAO level is a new prognostic marker for colorectal cancer.
    Biomarkers in medicine, 2017, Volume: 11, Issue:5

    Topics: Adult; Aged; Biomarkers, Tumor; Colorectal Neoplasms; Disease-Free Survival; Female; Humans; Male; M

2017
Plasma choline metabolites and colorectal cancer risk in the Women's Health Initiative Observational Study.
    Cancer research, 2014, Dec-15, Volume: 74, Issue:24

    Topics: Aged; Betaine; Choline; Colorectal Neoplasms; Female; Humans; Methylamines; Middle Aged; Risk Factor

2014
A genome-wide systems analysis reveals strong link between colorectal cancer and trimethylamine N-oxide (TMAO), a gut microbial metabolite of dietary meat and fat.
    BMC genomics, 2015, Volume: 16 Suppl 7

    Topics: Algorithms; Colorectal Neoplasms; Dietary Fats; Epigenesis, Genetic; Gastrointestinal Microbiome; Ge

2015