trimethyloxamine has been researched along with Cardiac Failure in 58 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Carnitine has been associated with cardiac energy metabolism and heart failure, but the association between its precursors-trimethyllysine (TML) and γ-butyrobetaine (GBB)-and heart failure with preserved ejection fraction (HFpEF) remains unclear." | 8.12 | Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events. ( Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L, 2022) |
| "Few studies have examined the associations of trimethylamine-N-oxide (TMAO) and its precursors (choline, betaine, dimethylglycine, and L-carnitine) with the risk of atrial fibrillation (AF) and heart failure (HF)." | 8.02 | Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study. ( Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E, 2021) |
| "Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients, is both elevated in the circulation of patients having heart failure and heralds worse overall prognosis." | 7.83 | Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure. ( Bhushan, S; Bradley, J; Hazen, SL; Lefer, DJ; Organ, CL; Otsuka, H; Polhemus, DJ; Tang, WH; Trivedi, R; Wang, Z; Wu, Y, 2016) |
| "Carnitine has been associated with cardiac energy metabolism and heart failure, but the association between its precursors-trimethyllysine (TML) and γ-butyrobetaine (GBB)-and heart failure with preserved ejection fraction (HFpEF) remains unclear." | 4.12 | Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events. ( Dong, E; Gao, J; Huang, M; Ji, L; Li, C; Wang, DW; Wang, Y; Wei, H; Wu, J; Zhang, Q; Zhao, C; Zhao, M; Zheng, L, 2022) |
| "Few studies have examined the associations of trimethylamine-N-oxide (TMAO) and its precursors (choline, betaine, dimethylglycine, and L-carnitine) with the risk of atrial fibrillation (AF) and heart failure (HF)." | 4.02 | Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study. ( Alonso-Gómez, A; Bulló, M; Clish, C; Corella, D; Estruch, R; Fiol, M; Fitó, M; Guasch-Ferré, M; Hernández-Alonso, P; Hu, FB; Li, J; Liang, L; Martínez-González, MA; Papandreou, C; Ros, E; Ruiz-Canela, M; Salas-Salvadó, J; Santos-Lozano, JM; Serra-Majem, L; Toledo, E, 2021) |
| "Trimethylamine N-oxide (TMAO), a gut-related metabolite, is associated with heart failure (HF) outcomes." | 4.02 | Association of gut-related metabolites with outcome in acute heart failure. ( Bernieh, D; Cassambai, S; Heaney, LM; Israr, MZ; Jones, DJL; Ng, LL; Salzano, A; Suzuki, T; Yazaki, Y, 2021) |
| "Background Patients at increased risk for coronary artery disease and adverse prognosis during heart failure exhibit increased levels of circulating trimethylamine N-oxide (TMAO), a metabolite formed in the metabolism of dietary phosphatidylcholine." | 3.96 | Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure. ( Goodchild, TT; Gupta, N; Hazen, SL; Lefer, DJ; Li, Z; Organ, CL; Polhemus, DJ; Sharp, TE; Tang, WHW, 2020) |
| "To determine if differences exist in plasma concentrations of TMAO, choline, or l-carnitine among dogs with DMVD and congestive heart failure (CHF), dogs with asymptomatic DMVD, and healthy control dogs." | 3.91 | A pilot study investigating circulating trimethylamine N-oxide and its precursors in dogs with degenerative mitral valve disease with or without congestive heart failure. ( Freeman, LM; Karlin, ET; Rush, JE, 2019) |
| "Trimethylamine N-oxide (TMAO), a gut microbe-dependent metabolite of dietary choline and other trimethylamine-containing nutrients, is both elevated in the circulation of patients having heart failure and heralds worse overall prognosis." | 3.83 | Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure. ( Bhushan, S; Bradley, J; Hazen, SL; Lefer, DJ; Organ, CL; Otsuka, H; Polhemus, DJ; Tang, WH; Trivedi, R; Wang, Z; Wu, Y, 2016) |
| "This case-cohort study included Chronic Renal Insufficiency Cohort participants with baseline diabetes, estimated glomerular filtration rate <60 mL/min/1." | 1.91 | Association of urine and plasma ADMA with atherosclerotic risk in DKD cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study. ( Anderson, AH; Bhat, Z; Brown, J; Brunengraber, H; Charleston, J; Chen, J; Feldman, HI; He, J; Hostetter, TH; Hsu, CY; Ix, JH; Kimmel, PL; Mehta, R; Rao, P; Sapa, H; Schelling, JR; Schrauben, SJ; Seegmiller, JC; Shafi, T; Shlipak, MG; Townsend, R; Vasan, RS; Xie, D; Zhang, X, 2023) |
| "Patients with congestive heart failure (HF) develop intestinal wall edema due to venous congestion, which impairs absorption function and allows bacterial overgrowth." | 1.72 | Gut microbiome in heart failure and aortic stenosis. ( Dvorožňáková, M; Fülöp, P; Fülöpová, Z; Šoltys, K; Vachalcová, M; Valočik, G, 2022) |
| "Cardiac function, plasma TMAO level, cardiac hypertrophy and fibrosis, expression of inflammatory, electrophysiological studies and signaling pathway were analyzed at the sixth week after AB surgery." | 1.56 | 3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice. ( Fu, H; Huang, H; Jiang, X; Kong, B; Shuai, W; Wang, G, 2020) |
| "TMAO-treated rats with heart failure had lower blood pressure and urinated more than untreated rats with the condition." | 1.56 | TMAO, a seafood-derived molecule, produces diuresis and reduces mortality in heart failure rats. ( Derzsi, L; Dobrowolski, L; Gawrys-Kopczynska, M; Holyst, R; Jaworska, K; Konop, M; Kraszewska, K; Maksymiuk, K; Mogilnicka, I; Pilz, M; Samborowska, E; Sozanski, K; Ufnal, M, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 19 (32.76) | 24.3611 |
| 2020's | 39 (67.24) | 2.80 |
| Authors | Studies |
|---|---|
| Lv, S | 1 |
| Wang, Y | 4 |
| Zhang, W | 1 |
| Shang, H | 2 |
| Bin-Jumah, MN | 1 |
| Gilani, SJ | 1 |
| Hosawi, S | 1 |
| Al-Abbasi, FA | 1 |
| Zeyadi, M | 1 |
| Imam, SS | 1 |
| Alshehri, S | 1 |
| Ghoneim, MM | 1 |
| Nadeem, MS | 1 |
| Kazmi, I | 1 |
| Chen, G | 1 |
| He, L | 1 |
| Dou, X | 1 |
| Liu, T | 1 |
| Konieczny, RA | 1 |
| Kuliczkowski, W | 2 |
| Salzano, A | 7 |
| Cassambai, S | 4 |
| Yazaki, Y | 7 |
| Israr, MZ | 6 |
| Bernieh, D | 4 |
| Wong, M | 2 |
| Suzuki, T | 9 |
| Gąsecka, A | 1 |
| Rzepa, Ł | 1 |
| Konwerski, M | 1 |
| Zawadzka, M | 1 |
| Wysocki, K | 1 |
| Budnik, M | 1 |
| Czub, P | 1 |
| Wilimski, R | 1 |
| Wondołkowski, M | 1 |
| Wilczyńska-Burlikowska, J | 1 |
| Scisło, P | 1 |
| Konop, M | 2 |
| Huczek, Z | 1 |
| Kochman, J | 1 |
| Kochanowski, J | 1 |
| Opolski, G | 1 |
| Filipiak, KJ | 1 |
| Ufnal, M | 3 |
| Kapłon-Cieślicka, A | 1 |
| Li, N | 1 |
| Zhou, J | 1 |
| Chen, R | 1 |
| Li, J | 3 |
| Zhao, X | 1 |
| Zhou, P | 1 |
| Liu, C | 1 |
| Song, L | 1 |
| Liao, Z | 1 |
| Wang, X | 2 |
| Yan, S | 1 |
| Zhao, H | 1 |
| Yan, H | 1 |
| Anderson, KM | 1 |
| Ferranti, EP | 1 |
| Alagha, EC | 1 |
| Mykityshyn, E | 1 |
| French, CE | 1 |
| Reilly, CM | 1 |
| Qiu, WD | 1 |
| Xiao, XJ | 1 |
| Xia, S | 1 |
| Gao, ZP | 1 |
| Li, LW | 1 |
| Konieczny, R | 1 |
| Żurawska-Płaksej, E | 1 |
| Kaaz, K | 1 |
| Czapor-Irzabek, H | 1 |
| Bombała, W | 1 |
| Mysiak, A | 1 |
| Yoshida, Y | 2 |
| Shimizu, I | 1 |
| Shimada, A | 1 |
| Nakahara, K | 1 |
| Yanagisawa, S | 1 |
| Kubo, M | 1 |
| Fukuda, S | 1 |
| Ishii, C | 1 |
| Yamamoto, H | 1 |
| Ishikawa, T | 1 |
| Kano, K | 1 |
| Aoki, J | 1 |
| Katsuumi, G | 1 |
| Suda, M | 1 |
| Ozaki, K | 1 |
| Okuda, S | 1 |
| Ohta, S | 1 |
| Okamoto, S | 1 |
| Minokoshi, Y | 1 |
| Oda, K | 1 |
| Sasaoka, T | 1 |
| Abe, M | 1 |
| Sakimura, K | 1 |
| Kubota, Y | 1 |
| Yoshimura, N | 1 |
| Kajimura, S | 1 |
| Zuriaga, M | 1 |
| Walsh, K | 1 |
| Soga, T | 1 |
| Minamino, T | 1 |
| Wei, H | 2 |
| Zhao, M | 2 |
| Wu, J | 1 |
| Li, C | 2 |
| Huang, M | 2 |
| Gao, J | 2 |
| Zhang, Q | 2 |
| Ji, L | 2 |
| Zhao, C | 2 |
| Dong, E | 2 |
| Zheng, L | 2 |
| Wang, DW | 2 |
| Fülöp, P | 1 |
| Dvorožňáková, M | 1 |
| Vachalcová, M | 1 |
| Fülöpová, Z | 1 |
| Šoltys, K | 1 |
| Valočik, G | 1 |
| Crisci, G | 1 |
| Cittadini, A | 1 |
| Bossone, E | 1 |
| Weng, JQ | 1 |
| Li, JB | 1 |
| Yuan, MF | 1 |
| Yao, TT | 1 |
| Zhang, JF | 1 |
| Zeng, YY | 1 |
| Zhao, J | 1 |
| Li, Y | 1 |
| Xu, K | 1 |
| Shen, XX | 1 |
| Gui, XY | 2 |
| Rabkin, SW | 2 |
| Schrauben, SJ | 1 |
| Sapa, H | 1 |
| Xie, D | 1 |
| Zhang, X | 2 |
| Anderson, AH | 1 |
| Shlipak, MG | 1 |
| Hsu, CY | 1 |
| Shafi, T | 1 |
| Mehta, R | 1 |
| Bhat, Z | 1 |
| Brown, J | 1 |
| Charleston, J | 1 |
| Chen, J | 1 |
| He, J | 1 |
| Ix, JH | 1 |
| Rao, P | 1 |
| Townsend, R | 1 |
| Kimmel, PL | 1 |
| Vasan, RS | 1 |
| Feldman, HI | 1 |
| Seegmiller, JC | 1 |
| Brunengraber, H | 1 |
| Hostetter, TH | 1 |
| Schelling, JR | 1 |
| Cui, H | 1 |
| Han, S | 1 |
| Dai, Y | 1 |
| Xie, W | 1 |
| Zheng, R | 1 |
| Sun, Y | 2 |
| Xia, X | 1 |
| Deng, X | 1 |
| Cao, Y | 1 |
| Zhang, M | 1 |
| Belli, M | 1 |
| Barone, L | 1 |
| Longo, S | 1 |
| Prandi, FR | 1 |
| Lecis, D | 1 |
| Mollace, R | 1 |
| Margonato, D | 1 |
| Muscoli, S | 1 |
| Sergi, D | 1 |
| Federici, M | 1 |
| Barillà, F | 1 |
| Heaney, LM | 3 |
| Kanagala, P | 1 |
| Singh, A | 1 |
| Arnold, JR | 1 |
| Gulsin, GS | 1 |
| Squire, IB | 1 |
| McCann, GP | 1 |
| Ng, LL | 6 |
| Formiga, F | 1 |
| Ferreira Teles, CI | 1 |
| Chivite, D | 1 |
| Kuehn, BM | 1 |
| Zhou, X | 3 |
| Jin, M | 2 |
| Liu, L | 1 |
| Yu, Z | 1 |
| Lu, X | 1 |
| Zhang, H | 1 |
| Wang, G | 1 |
| Kong, B | 1 |
| Shuai, W | 1 |
| Fu, H | 1 |
| Jiang, X | 1 |
| Huang, H | 1 |
| Jin, B | 1 |
| Ji, F | 1 |
| Zuo, A | 1 |
| Liu, H | 1 |
| Qi, L | 1 |
| He, Y | 1 |
| Wang, Q | 1 |
| Zhao, P | 1 |
| Organ, CL | 2 |
| Li, Z | 1 |
| Sharp, TE | 1 |
| Polhemus, DJ | 2 |
| Gupta, N | 1 |
| Goodchild, TT | 1 |
| Tang, WHW | 1 |
| Hazen, SL | 3 |
| Lefer, DJ | 2 |
| Gawrys-Kopczynska, M | 1 |
| Maksymiuk, K | 1 |
| Kraszewska, K | 2 |
| Derzsi, L | 1 |
| Sozanski, K | 1 |
| Holyst, R | 1 |
| Pilz, M | 1 |
| Samborowska, E | 2 |
| Dobrowolski, L | 1 |
| Jaworska, K | 2 |
| Mogilnicka, I | 2 |
| Aizawa, K | 1 |
| Negishi, K | 1 |
| Saitoh, Y | 1 |
| Kimura, N | 1 |
| Kono, K | 1 |
| Heaney, L | 1 |
| Lai, F | 1 |
| Imai, Y | 1 |
| Kario, K | 1 |
| Nagai, R | 1 |
| Zhang, Y | 1 |
| Ke, B | 1 |
| Du, J | 1 |
| Drapala, A | 1 |
| Szudzik, M | 1 |
| Chabowski, D | 1 |
| Dong, Z | 2 |
| Liang, Z | 1 |
| Liu, W | 1 |
| Zhao, L | 1 |
| Wang, S | 1 |
| Hai, X | 2 |
| Yu, K | 1 |
| Li, W | 1 |
| Huang, A | 1 |
| Zhu, H | 1 |
| Liu, X | 1 |
| Huang, X | 1 |
| Huang, Y | 2 |
| Cai, X | 1 |
| Lu, J | 1 |
| Atherton, JJ | 1 |
| Punyadeera, C | 1 |
| Zheng, S | 1 |
| Shen, Z | 1 |
| Luo, Y | 1 |
| Papandreou, C | 1 |
| Bulló, M | 1 |
| Hernández-Alonso, P | 1 |
| Ruiz-Canela, M | 1 |
| Guasch-Ferré, M | 1 |
| Toledo, E | 1 |
| Clish, C | 1 |
| Corella, D | 1 |
| Estruch, R | 1 |
| Ros, E | 1 |
| Fitó, M | 1 |
| Alonso-Gómez, A | 1 |
| Fiol, M | 1 |
| Santos-Lozano, JM | 1 |
| Serra-Majem, L | 1 |
| Liang, L | 1 |
| Martínez-González, MA | 1 |
| Hu, FB | 1 |
| Salas-Salvadó, J | 1 |
| Jones, DJL | 2 |
| Mollar, A | 1 |
| Marrachelli, VG | 1 |
| Núñez, E | 1 |
| Monleon, D | 1 |
| Bodí, V | 1 |
| Sanchis, J | 1 |
| Navarro, D | 1 |
| Núñez, J | 1 |
| Kinugasa, Y | 1 |
| Nakamura, K | 1 |
| Kamitani, H | 1 |
| Hirai, M | 1 |
| Yanagihara, K | 1 |
| Kato, M | 1 |
| Yamamoto, K | 1 |
| Yuzefpolskaya, M | 1 |
| Bohn, B | 1 |
| Javaid, A | 1 |
| Mondellini, GM | 1 |
| Braghieri, L | 1 |
| Pinsino, A | 1 |
| Onat, D | 1 |
| Cagliostro, B | 1 |
| Kim, A | 1 |
| Takeda, K | 1 |
| Naka, Y | 1 |
| Farr, M | 1 |
| Sayer, GT | 1 |
| Uriel, N | 1 |
| Nandakumar, R | 1 |
| Mohan, S | 1 |
| Colombo, PC | 1 |
| Demmer, RT | 1 |
| Yu, T | 1 |
| Shen, X | 1 |
| Ni, L | 1 |
| Wang, Z | 3 |
| Subramaniam, S | 1 |
| Fletcher, C | 1 |
| Cui, X | 1 |
| Ye, L | 1 |
| Jin, L | 1 |
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| Li, L | 1 |
| Geng, B | 1 |
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| Cai, J | 1 |
| Voors, AA | 2 |
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| Cleland, JG | 2 |
| Dickstein, K | 1 |
| Filippatos, G | 1 |
| Hillege, HL | 1 |
| Lang, CC | 2 |
| Ponikowski, P | 1 |
| Samani, NJ | 2 |
| van Veldhuisen, DJ | 1 |
| Zannad, F | 1 |
| Zwinderman, AH | 1 |
| Metra, M | 2 |
| Karlin, ET | 1 |
| Rush, JE | 1 |
| Freeman, LM | 1 |
| Chioncel, O | 1 |
| Ambrosy, AP | 1 |
| Polsinelli, VB | 1 |
| Marteau, L | 1 |
| Shah, SJ | 1 |
| Qian, Z | 1 |
| Yin, J | 1 |
| Xu, W | 1 |
| Li, X | 1 |
| Wang, J | 1 |
| Nelson, CP | 1 |
| Trøseid, M | 1 |
| Ueland, T | 1 |
| Hov, JR | 1 |
| Svardal, A | 1 |
| Gregersen, I | 1 |
| Dahl, CP | 1 |
| Aakhus, S | 1 |
| Gude, E | 1 |
| Bjørndal, B | 1 |
| Halvorsen, B | 1 |
| Karlsen, TH | 1 |
| Aukrust, P | 1 |
| Gullestad, L | 1 |
| Berge, RK | 1 |
| Yndestad, A | 1 |
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| Fan, Y | 1 |
| Levison, B | 1 |
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| Bhushan, S | 1 |
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| Trivedi, R | 1 |
| Bhandari, SS | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Association Analysis of Cardiovascular and Nervous System Diseases and Intestinal Microbiome Based on Multi-omics Big Data and Related Applications[NCT06099496] | 490 participants (Anticipated) | Observational [Patient Registry] | 2023-04-01 | Recruiting | |||
| GutHeart: Targeting Gut Microbiota to Treat Heart Failure[NCT02637167] | Phase 2 | 150 participants (Anticipated) | Interventional | 2016-03-11 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
18 reviews available for trimethyloxamine and Cardiac Failure
| Article | Year |
|---|---|
Trimethylamine oxide: a potential target for heart failure therapy.
Topics: Cardiotonic Agents; Carnitine; Choline; Diuretics; Gastrointestinal Microbiome; Heart Failure; Human | 2022 |
Pathobiological Relationship of Excessive Dietary Intake of Choline/L-Carnitine: A TMAO Precursor-Associated Aggravation in Heart Failure in Sarcopenic Patients.
Topics: Biodiversity; Biomarkers; Carnitine; Choline; Dietary Supplements; Disease Susceptibility; Dysbiosis | 2021 |
Association of Trimethylamine-N-Oxide Levels with Risk of Cardiovascular Disease and Mortality among Elderly Subjects: A Systematic Review and Meta-Analysis.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Heart Failure; Humans; Methylamines; Oxides; Prospective | 2022 |
Trimethylamine N-oxide in cardiovascular disease.
Topics: Cardiovascular Diseases; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines | 2022 |
The Gut Axis Involvement in Heart Failure: Focus on Trimethylamine N-oxide.
Topics: Choline; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines | 2022 |
The heart and gut relationship: a systematic review of the evaluation of the microbiome and trimethylamine-N-oxide (TMAO) in heart failure.
Topics: Heart Failure; Humans; Methylamines; Microbiota; Oxides; RNA, Ribosomal, 16S | 2022 |
C-Reactive Protein, Interleukin-6, Trimethylamine-N-Oxide, Syndecan-1, Nitric Oxide, and Tumor Necrosis Factor Receptor-1 in Heart Failure with Preserved Versus Reduced Ejection Fraction: a Meta-Analysis.
Topics: Biomarkers; C-Reactive Protein; Heart Failure; Humans; Interleukin-6; Natriuretic Peptide, Brain; Ni | 2023 |
C-Reactive Protein, Interleukin-6, Trimethylamine-N-Oxide, Syndecan-1, Nitric Oxide, and Tumor Necrosis Factor Receptor-1 in Heart Failure with Preserved Versus Reduced Ejection Fraction: a Meta-Analysis.
Topics: Biomarkers; C-Reactive Protein; Heart Failure; Humans; Interleukin-6; Natriuretic Peptide, Brain; Ni | 2023 |
C-Reactive Protein, Interleukin-6, Trimethylamine-N-Oxide, Syndecan-1, Nitric Oxide, and Tumor Necrosis Factor Receptor-1 in Heart Failure with Preserved Versus Reduced Ejection Fraction: a Meta-Analysis.
Topics: Biomarkers; C-Reactive Protein; Heart Failure; Humans; Interleukin-6; Natriuretic Peptide, Brain; Ni | 2023 |
C-Reactive Protein, Interleukin-6, Trimethylamine-N-Oxide, Syndecan-1, Nitric Oxide, and Tumor Necrosis Factor Receptor-1 in Heart Failure with Preserved Versus Reduced Ejection Fraction: a Meta-Analysis.
Topics: Biomarkers; C-Reactive Protein; Heart Failure; Humans; Interleukin-6; Natriuretic Peptide, Brain; Ni | 2023 |
Gut microbiota and integrative traditional Chinese and western medicine in prevention and treatment of heart failure.
Topics: Drugs, Chinese Herbal; Gastrointestinal Microbiome; Heart Failure; Humans; Medicine, Chinese Traditi | 2023 |
Gut Microbiota Composition and Cardiovascular Disease: A Potential New Therapeutic Target?
Topics: Cardiovascular Diseases; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines | 2023 |
Impact of intestinal microbiota in patients with heart failure: A systematic review.
Topics: Biomarkers; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines; Prognosis | 2019 |
The Gut Axis Involvement in Heart Failure: Focus on Trimethylamine N-oxide.
Topics: Biomarkers; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines; Prognosis; Stroke Volu | 2020 |
TMAO: how gut microbiota contributes to heart failure.
Topics: Gastrointestinal Microbiome; Heart Failure; Humans; Intestinal Mucosa; Methylamines | 2021 |
Gut microbiota-derived trimethylamine N-oxide is associated with poor prognosis in patients with heart failure.
Topics: Cause of Death; Gastrointestinal Microbiome; Heart Failure; Heart Transplantation; Hospitalization; | 2020 |
Trimethylamine N-oxide: breathe new life.
Topics: Animals; Brain Diseases; Heart Failure; Humans; Methylamines; Neoplasms; Obesity; Thrombosis | 2018 |
The role of splanchnic congestion and the intestinal microenvironment in the pathogenesis of advanced heart failure.
Topics: Disease Progression; Enterocytes; Fatty Acids, Volatile; Gastrointestinal Microbiome; Heart Failure; | 2019 |
The role of intestinal microbiota in cardiovascular disease.
Topics: Bile Acids and Salts; Cardiovascular Diseases; Dysbiosis; Fatty Acids; Gastrointestinal Microbiome; | 2019 |
Intersections Between Microbiome and Heart Failure: Revisiting the Gut Hypothesis.
Topics: Female; Gastrointestinal Microbiome; Heart Failure; Homeostasis; Humans; Male; Methylamines; Microbi | 2015 |
Exploring the Microbiome in Heart Failure.
Topics: Cardio-Renal Syndrome; Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines; Microbiota | 2016 |
1 trial available for trimethyloxamine and Cardiac Failure
| Article | Year |
|---|---|
Bacterial metabolites trimethylamine N-oxide and butyrate as surrogates of small intestinal bacterial overgrowth in patients with a recent decompensated heart failure.
Topics: Aged; Bacteria; Biomarkers; Blind Loop Syndrome; Breath Tests; Butyrates; Female; Heart Failure; Hum | 2021 |
39 other studies available for trimethyloxamine and Cardiac Failure
| Article | Year |
|---|---|
Trimethylamine-N-oxide (TMAO) versus echocardiographic, biochemical and histopathological indices of heart failure in patients with severe aortic stenosis: Rationale and design of the prospective, observational TASTE study.
Topics: Aortic Valve Stenosis; Echocardiography; Heart Failure; Humans; Methylamines; Oxides; Prospective St | 2022 |
Association between trimethylamine N-oxide and prognosis of patients with acute myocardial infarction and heart failure.
Topics: C-Reactive Protein; Heart Failure; Humans; Myocardial Infarction; Prognosis | 2022 |
[Predictive value of plasma TMAO combined with NT-proBNP on the prognosis and length of hospitalization of patients with ischemic heart failure].
Topics: Aged; Biomarkers; Female; Heart Failure; Hospitalization; Humans; Male; Methylamines; Middle Aged; N | 2022 |
All-Cause Mortality and Trimethylamine N-Oxide Levels in Patients with Cardiovascular Disease.
Topics: Atrial Fibrillation; Biomarkers; Cardiovascular Diseases; Female; Heart Failure; Humans; Male; Methy | 2022 |
Brown adipose tissue dysfunction promotes heart failure via a trimethylamine N-oxide-dependent mechanism.
Topics: Adipocytes, Brown; Adipose Tissue, Brown; Animals; Choline; Heart Failure; Methylamines; Mice; Myoca | 2022 |
Association of Systemic Trimethyllysine With Heart Failure With Preserved Ejection Fraction and Cardiovascular Events.
Topics: Carnitine; Cross-Sectional Studies; Heart Failure; Humans; Prospective Studies; Stroke Volume | 2022 |
Gut microbiome in heart failure and aortic stenosis.
Topics: Aortic Valve Stenosis; Gastrointestinal Microbiome; Heart Failure; Humans; Lipopolysaccharides; Meth | 2022 |
Heart failure and trimethylamine N-oxide: time to transform a 'gut feeling' in a fact?
Topics: Heart Failure; Humans; Methylamines | 2023 |
Effects of Buyang Huanwu Decoction on Intestinal Barrier, Intestinal Flora, and Trimethylamine Oxide in Rats with Heart Failure.
Topics: Animals; Chromatography, Liquid; Claudin-1; Drugs, Chinese Herbal; Gastrointestinal Microbiome; Hear | 2023 |
Association of urine and plasma ADMA with atherosclerotic risk in DKD cardiovascular disease risk in diabetic kidney disease: findings from the Chronic Renal Insufficiency Cohort (CRIC) study.
Topics: Arginine; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Cohort Studies; Diabetes Mellitus; D | 2023 |
Combined use of trimethylamine N-oxide with BNP for risk stratification in heart failure with preserved ejection fraction: findings from the DIAMONDHFpEF study.
Topics: Aged; Biomarkers; Case-Control Studies; Female; Heart Failure; Humans; Male; Methylamines; Middle Ag | 2020 |
Gut Microbes Role in Heart Failure Explored.
Topics: Atherosclerosis; Bacteria; Butyrates; Diet; Dietary Fiber; Gastrointestinal Microbiome; Heart Failur | 2019 |
Trimethylamine N-oxide and cardiovascular outcomes in patients with chronic heart failure after myocardial infarction.
Topics: Aged; Aged, 80 and over; Biomarkers; Female; Follow-Up Studies; Heart Failure; Humans; Male; Methyla | 2020 |
3,3-Dimethyl-1-butanol attenuates cardiac remodeling in pressure-overload-induced heart failure mice.
Topics: Animals; Cardiomegaly; Disease Models, Animal; Echocardiography; Electrocardiography; Fibroblasts; H | 2020 |
Destructive Role of TMAO in T-Tubule and Excitation-Contraction Coupling in the Adult Cardiomyocytes.
Topics: Animals; Calcium; Cells, Cultured; Excitation Contraction Coupling; Heart Failure; Male; Membrane Pr | 2020 |
Nonlethal Inhibition of Gut Microbial Trimethylamine N-oxide Production Improves Cardiac Function and Remodeling in a Murine Model of Heart Failure.
Topics: Animals; Bacteria; Bacterial Proteins; Choline; Disease Models, Animal; Down-Regulation; Enzyme Inhi | 2020 |
TMAO, a seafood-derived molecule, produces diuresis and reduces mortality in heart failure rats.
Topics: Angiotensins; Animals; Diuresis; Gene Expression Regulation; Heart Failure; Kidney; Male; Methylamin | 2020 |
Ethnic differences in association of outcomes with trimethylamine N-oxide in acute heart failure patients.
Topics: Cohort Studies; Heart Failure; Humans; Methylamines | 2020 |
Heart Failure Disturbs Gut-Blood Barrier and Increases Plasma Trimethylamine, a Toxic Bacterial Metabolite.
Topics: Animals; Bacteria; Chromatography, High Pressure Liquid; Feces; Gastrointestinal Microbiome; Heart F | 2020 |
The correlation between plasma trimethylamine N-oxide level and heart failure classification in northern Chinese patients.
Topics: Biomarkers; China; Heart Failure; Humans; Methylamines; Predictive Value of Tests; Prognosis | 2020 |
Should patients with heart failure listen to their gut?
Topics: Gastrointestinal Microbiome; Heart Failure; Humans; Methylamines; Prognosis | 2020 |
Trimethylamine N-Oxide is Associated with Heart Failure Risk in Patients with Preserved Ejection Fraction.
Topics: Biomarkers; Heart Failure; Humans; Methylamines; Natriuretic Peptide, Brain; Peptide Fragments; Prog | 2021 |
Choline Metabolism and Risk of Atrial Fibrillation and Heart Failure in the PREDIMED Study.
Topics: Aged; Atrial Fibrillation; Betaine; Carnitine; Case-Control Studies; Choline; Female; Heart Failure; | 2021 |
Association of gut-related metabolites with outcome in acute heart failure.
Topics: Acetylcarnitine; Acute Disease; Aged; Aged, 80 and over; Betaine; Carnitine; Choline; Female; Gastro | 2021 |
Trimethylamine N-oxide and outcomes in patients hospitalized with acute heart failure and preserved ejection fraction.
Topics: Aftercare; Heart Failure; Humans; Methylamines; Patient Discharge; Risk Factors; Stroke Volume | 2021 |
Levels of Trimethylamine N-Oxide Remain Elevated Long Term After Left Ventricular Assist Device and Heart Transplantation and Are Independent From Measures of Inflammation and Gut Dysbiosis.
Topics: Aged; Aged, 80 and over; Dysbiosis; Female; Gastrointestinal Microbiome; Heart Failure; Heart Transp | 2021 |
FMO3-TMAO axis modulates the clinical outcome in chronic heart-failure patients with reduced ejection fraction: evidence from an Asian population.
Topics: Carnitine; Choline; Chronic Disease; Heart Failure; Humans; Methylamines; Oxygenases; Prospective St | 2022 |
Metagenomic and metabolomic analyses unveil dysbiosis of gut microbiota in chronic heart failure patients.
Topics: Adult; Aged; Bacteria; Butyrates; Dysbiosis; Female; Gastrointestinal Microbiome; Heart Failure; Hum | 2018 |
Association with outcomes and response to treatment of trimethylamine N-oxide in heart failure: results from BIOSTAT-CHF.
Topics: Biomarkers, Pharmacological; Disease Progression; Europe; Female; Heart Failure; Hospitalization; Hu | 2019 |
A pilot study investigating circulating trimethylamine N-oxide and its precursors in dogs with degenerative mitral valve disease with or without congestive heart failure.
Topics: Animals; Carnitine; Case-Control Studies; Choline; Cross-Sectional Studies; Dog Diseases; Dogs; Echo | 2019 |
Trimethylamine N-oxide and risk of heart failure progression: marker or mediator of disease.
Topics: Biomarkers; Disease Progression; Heart Failure; Humans; Methylamines | 2019 |
Reductions in gut microbiota‑derived metabolite trimethylamine N‑oxide in the circulation may ameliorate myocardial infarction‑induced heart failure in rats, possibly by inhibiting interleukin‑8 secretion.
Topics: Animals; Gastrointestinal Microbiome; Heart Failure; Hexanols; Interleukin-8; Male; Methylamines; My | 2019 |
Geographical location affects the levels and association of trimethylamine N-oxide with heart failure mortality in BIOSTAT-CHF: a post-hoc analysis.
Topics: Aged; Aged, 80 and over; Female; Heart Failure; Humans; Internationality; Male; Methylamines; Middle | 2019 |
Microbiota-dependent metabolite trimethylamine-N-oxide is associated with disease severity and survival of patients with chronic heart failure.
Topics: Aged; Betaine; Biomarkers; Choline; Chronic Disease; Female; Heart Failure; Humans; Intestinal Mucos | 2015 |
Prognostic value of elevated levels of intestinal microbe-generated metabolite trimethylamine-N-oxide in patients with heart failure: refining the gut hypothesis.
Topics: Aged; Biomarkers; Female; Follow-Up Studies; Heart Failure; Humans; Intestinal Mucosa; Intestines; K | 2014 |
Gut feelings about heart failure.
Topics: Female; Heart Failure; Humans; Intestinal Mucosa; Male; Methylamines; Microbiota; Risk Assessment | 2014 |
Choline Diet and Its Gut Microbe-Derived Metabolite, Trimethylamine N-Oxide, Exacerbate Pressure Overload-Induced Heart Failure.
Topics: Animals; Bacteria; Cardiomegaly; Choline; Diet; Disease Models, Animal; Disease Progression; Fibrosi | 2016 |
Trimethylamine N-oxide and prognosis in acute heart failure.
Topics: Acute Disease; Aged; Aged, 80 and over; Biomarkers; Chi-Square Distribution; Chromatography, Liquid; | 2016 |
Trimethylamine-N-oxide (TMAO) predicts fatal outcomes in community-acquired pneumonia patients without evident coronary artery disease.
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cause of Death; Cerebrovascular Disorde | 2016 |