trimethyloxamine has been researched along with Arteriosclerosis, Coronary in 32 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Trimethylamine N-oxide (TMAO) is reportedly associated with deteriorating metabolic profiles and cardiovascular diseases." | 8.31 | Association of Circulating Trimethylamine-N Oxide With Malnutrition and the Risk of Coronary Artery Disease in Patients With Maintenance Hemodialysis. ( Huang, Y; Liu, J; Peng, L; Tang, C; Wang, H; Wei, X; Yuan, X, 2023) |
| " Trimethylamine N-oxide (TMAO) is reportedly associated with deteriorating metabolic profiles and cardiovascular diseases." | 4.31 | Association of Circulating Trimethylamine-N Oxide With Malnutrition and the Risk of Coronary Artery Disease in Patients With Maintenance Hemodialysis. ( Huang, Y; Liu, J; Peng, L; Tang, C; Wang, H; Wei, X; Yuan, X, 2023) |
| "Inflammation is believed to play a key role by providing matrix-degrading metalloproteinases and also by inducing death of matrix-synthesizing smooth muscle cells." | 2.50 | Biomarkers of plaque instability. ( Shah, PK, 2014) |
| "45." | 1.62 | Association of plasma trimethylamine N-Oxide level with healed culprit plaques examined by optical coherence tomography in patients with ST-Segment elevation myocardial infarction. ( Chen, R; Chen, Y; Li, J; Liu, C; Sheng, Z; Song, L; Tan, Y; Yan, H; Zhao, H; Zhou, J; Zhou, P, 2021) |
| "Gut dysbiosis was associated with increased levels of TMAO, immature OCN-expressing EPCs, and CAD." | 1.62 | Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease. ( Ahmad, A; Corban, MT; Horwath, IE; Lerman, A; Lerman, LO; Loeffler, DL; Marietta, EV; Murray, JA; Ozcan, I; Sara, JD; Toya, T, 2021) |
| "The median TMAO levels in patients with STEMI and healthy controls were 2." | 1.51 | Relation of Circulating Trimethylamine N-Oxide With Coronary Atherosclerotic Burden in Patients With ST-segment Elevation Myocardial Infarction. ( Chen, R; Chen, Y; Li, J; Liu, C; Sheng, Z; Song, L; Tan, Y; Yan, H; Zhao, H; Zhou, J; Zhou, P, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 17 (53.13) | 24.3611 |
| 2020's | 15 (46.88) | 2.80 |
| Authors | Studies |
|---|---|
| Li, Y | 1 |
| Cui, M | 1 |
| Sun, J | 1 |
| Wei, Q | 1 |
| Liu, M | 1 |
| Zhang, J | 2 |
| Qi, H | 1 |
| Zhao, L | 1 |
| Fang, H | 1 |
| Chen, Z | 1 |
| Lü, S | 1 |
| Amrein, M | 1 |
| Li, XS | 4 |
| Walter, J | 1 |
| Wang, Z | 5 |
| Zimmermann, T | 1 |
| Strebel, I | 1 |
| Honegger, U | 1 |
| Leu, K | 1 |
| Schäfer, I | 1 |
| Twerenbold, R | 1 |
| Puelacher, C | 1 |
| Glarner, N | 1 |
| Nestelberger, T | 1 |
| Koechlin, L | 1 |
| Ceresa, B | 1 |
| Haaf, P | 1 |
| Bakula, A | 1 |
| Zellweger, M | 1 |
| Hazen, SL | 5 |
| Mueller, C | 1 |
| Kuo, CH | 1 |
| Liu, CH | 1 |
| Wang, JH | 1 |
| Hsu, BG | 1 |
| Bjørnestad, EØ | 1 |
| Dhar, I | 1 |
| Svingen, GFT | 1 |
| Pedersen, ER | 1 |
| Ørn, S | 1 |
| Svenningsson, MM | 1 |
| Tell, GS | 1 |
| Ueland, PM | 1 |
| Sulo, G | 1 |
| Laaksonen, R | 1 |
| Nygård, O | 1 |
| Badran, M | 1 |
| Khalyfa, A | 1 |
| Ericsson, AC | 1 |
| Puech, C | 1 |
| McAdams, Z | 1 |
| Bender, SB | 1 |
| Gozal, D | 1 |
| Huang, Y | 2 |
| Zhang, H | 1 |
| Fan, X | 1 |
| Wang, J | 2 |
| Yin, Y | 1 |
| Zhang, Y | 1 |
| Shi, K | 1 |
| Yu, F | 1 |
| Yuan, X | 1 |
| Wei, X | 1 |
| Liu, J | 1 |
| Tang, C | 1 |
| Peng, L | 1 |
| Wang, H | 1 |
| Koay, YC | 1 |
| Chen, YC | 1 |
| Wali, JA | 1 |
| Luk, AWS | 1 |
| Li, M | 1 |
| Doma, H | 1 |
| Reimark, R | 1 |
| Zaldivia, MTK | 1 |
| Habtom, HT | 1 |
| Franks, AE | 1 |
| Fusco-Allison, G | 1 |
| Yang, J | 2 |
| Holmes, A | 1 |
| Simpson, SJ | 1 |
| Peter, K | 1 |
| O'Sullivan, JF | 1 |
| Zhang, B | 1 |
| Wang, X | 2 |
| Xia, R | 1 |
| Li, C | 1 |
| Heianza, Y | 1 |
| Qi, L | 1 |
| Bin Waleed, K | 1 |
| Lu, Y | 1 |
| Liu, Q | 1 |
| Zeng, F | 1 |
| Tu, H | 1 |
| Wei, Y | 1 |
| Xu, S | 1 |
| Zhang, Z | 1 |
| Rongfeng, Y | 1 |
| Fan, A | 1 |
| Altaf, A | 1 |
| Chang, J | 1 |
| Wang, L | 2 |
| Li, J | 4 |
| Sheng, Z | 3 |
| Tan, Y | 3 |
| Zhou, P | 3 |
| Liu, C | 3 |
| Zhao, H | 3 |
| Song, L | 3 |
| Zhou, J | 3 |
| Chen, R | 2 |
| Chen, Y | 3 |
| Yan, H | 3 |
| Tang, WHW | 1 |
| Wu, Y | 4 |
| Khaw, KT | 1 |
| Wareham, NJ | 1 |
| Nieuwdorp, M | 1 |
| Boekholdt, SM | 1 |
| Ma, R | 1 |
| Fu, W | 1 |
| Hu, X | 1 |
| Jiang, H | 1 |
| Toya, T | 1 |
| Ozcan, I | 1 |
| Corban, MT | 1 |
| Sara, JD | 1 |
| Marietta, EV | 1 |
| Ahmad, A | 1 |
| Horwath, IE | 1 |
| Loeffler, DL | 1 |
| Murray, JA | 1 |
| Lerman, LO | 1 |
| Lerman, A | 1 |
| Liu, X | 1 |
| Xie, Z | 1 |
| Sun, M | 1 |
| Cui, J | 1 |
| Zhang, F | 1 |
| Yin, L | 1 |
| Huang, D | 1 |
| Hou, J | 1 |
| Tian, J | 1 |
| Yu, B | 1 |
| Malik, M | 1 |
| Suboc, TM | 1 |
| Tyagi, S | 1 |
| Salzman, N | 1 |
| Ying, R | 1 |
| Tanner, MJ | 1 |
| Kakarla, M | 1 |
| Baker, JE | 1 |
| Widlansky, ME | 1 |
| Qian, H | 1 |
| Sun, Z | 1 |
| Qiao, S | 1 |
| Xu, B | 1 |
| Gao, R | 1 |
| Trøseid, M | 2 |
| Mayerhofer, CCK | 1 |
| Broch, K | 1 |
| Arora, S | 1 |
| Svardal, A | 2 |
| Hov, JR | 1 |
| Andreassen, AK | 1 |
| Gude, E | 1 |
| Karason, K | 1 |
| Dellgren, G | 1 |
| Berge, RK | 2 |
| Gullestad, L | 1 |
| Aukrust, P | 2 |
| Ueland, T | 2 |
| Shah, PK | 1 |
| Srinivasa, S | 1 |
| Fitch, KV | 1 |
| Lo, J | 1 |
| Kadar, H | 1 |
| Knight, R | 1 |
| Wong, K | 1 |
| Abbara, S | 1 |
| Gauguier, D | 1 |
| Capeau, J | 1 |
| Boccara, F | 1 |
| Grinspoon, SK | 1 |
| Stubbs, JR | 1 |
| House, JA | 1 |
| Ocque, AJ | 1 |
| Zhang, S | 1 |
| Johnson, C | 1 |
| Kimber, C | 1 |
| Schmidt, K | 1 |
| Gupta, A | 1 |
| Wetmore, JB | 1 |
| Nolin, TD | 1 |
| Spertus, JA | 1 |
| Yu, AS | 1 |
| Haissman, JM | 1 |
| Knudsen, A | 1 |
| Hoel, H | 1 |
| Kjær, A | 1 |
| Kristoffersen, US | 1 |
| Katzenstein, TL | 1 |
| Lebech, AM | 1 |
| Nielsen, SD | 1 |
| Mafune, A | 1 |
| Iwamoto, T | 1 |
| Tsutsumi, Y | 1 |
| Nakashima, A | 1 |
| Yamamoto, I | 1 |
| Yokoyama, K | 1 |
| Yokoo, T | 1 |
| Urashima, M | 1 |
| Spector, R | 1 |
| Senthong, V | 3 |
| Hudec, T | 1 |
| Coughlin, J | 1 |
| Levison, B | 1 |
| Tang, WH | 3 |
| Fan, Y | 2 |
| Ottiger, M | 1 |
| Nickler, M | 1 |
| Steuer, C | 1 |
| Odermatt, J | 1 |
| Huber, A | 1 |
| Christ-Crain, M | 1 |
| Henzen, C | 1 |
| Hoess, C | 1 |
| Thomann, R | 1 |
| Zimmerli, W | 1 |
| Mueller, B | 1 |
| Schuetz, P | 1 |
| Fu, Q | 1 |
| Zhao, M | 1 |
| Wang, D | 1 |
| Hu, H | 1 |
| Guo, C | 1 |
| Chen, W | 1 |
| Li, Q | 1 |
| Zheng, L | 1 |
| Chen, B | 1 |
| Meyer, KA | 1 |
| Benton, TZ | 1 |
| Bennett, BJ | 1 |
| Jacobs, DR | 1 |
| Lloyd-Jones, DM | 1 |
| Gross, MD | 1 |
| Carr, JJ | 1 |
| Gordon-Larsen, P | 1 |
| Zeisel, SH | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| BASEL VIII Trial - Biochemical and Electrocardiographic Signatures in the Detection of Exercise-induced Myocardial Ischemia[NCT01838148] | 4,000 participants (Anticipated) | Observational | 2004-05-31 | Recruiting | |||
| Effect of Probiotic Supplementation on Endothelial Function in Men With Coronary Artery Disease[NCT01952834] | Phase 4 | 21 participants (Actual) | Interventional | 2013-06-30 | Completed | ||
| Pre-intervention and Post-intervention Optical Coherence Tomography Examination for Culprit Lesion in Patients With ST-segment Elevation Myocardial Infarction[NCT03593928] | 400 participants (Anticipated) | Observational | 2017-03-29 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
A measurement of endothelial function in humans that reports the percent change in brachial artery diameter to a flow stimulus in the arm induced by 5 minutes of occlusion of flow to the arm. It is measured as the percent change from baseline diameter. (NCT01952834)
Timeframe: % Change before and after 6 weeks of daily Probiotic
| Intervention | percent change (Mean) |
|---|---|
| GoodBelly Probiotic and Vancomycin | 1.2 |
Flow Mediated Dilation is measured as the percent change in brachial artery diameter as measured by high resolution ultrasound based on arterial diameter prior to and following 5 minute flow occlusion to the forearm . We measured the percent change in brachial diameter before vancomycin was started and again 10 days after vancomycin (NCT01952834)
Timeframe: Change before and after 10 days of Vancomycin, approximately 12 weeks from baseline
| Intervention | percent change (Mean) |
|---|---|
| GoodBelly Probiotic and Vancomycin | -0.2 |
Circulating cytokine measured in the plasma (NCT01952834)
Timeframe: Change before and after 6 weeks of daily Probiotic
| Intervention | pg/mL (Mean) |
|---|---|
| GoodBelly Probiotic and Vancomycin | -3.5 |
This is a circulating plasma cytokine (NCT01952834)
Timeframe: Change before and after 6 weeks of probiotic
| Intervention | pg/mL (Mean) |
|---|---|
| Probiotic Supplementation | -10.4 |
5 reviews available for trimethyloxamine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
[Gut microbiota and its metabolite trimethylamine-N-oxide (TMAO): a novel regulator in coronary artery disease].
Topics: Coronary Artery Disease; Gastrointestinal Microbiome; Humans; Methylamines; Oxides | 2021 |
The Role of Gut Microbiota and Trimethylamine N-oxide in Cardiovascular Diseases.
Topics: Cardiovascular Diseases; Coronary Artery Disease; Gastrointestinal Microbiome; Humans; Methylamines; | 2023 |
Gut microbiota in coronary artery disease: a friend or foe?
Topics: Animals; Bacteria; Coronary Artery Disease; Coronary Vessels; Dysbiosis; Gastrointestinal Microbiome | 2020 |
Biomarkers of plaque instability.
Topics: Antigens, Human Platelet; Apolipoprotein A-I; Atherosclerosis; Biomarkers; C-Reactive Protein; Coron | 2014 |
New Insight into the Dietary Cause of Atherosclerosis: Implications for Pharmacology.
Topics: Animals; Cholesterol; Coronary Artery Disease; Diet; Diet, Vegetarian; Humans; Hydroxymethylglutaryl | 2016 |
2 trials available for trimethyloxamine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Association of trimethylamine N-oxide with coronary atherosclerotic burden in patients with non-ST-segment elevation myocardial infarction.
Topics: Adolescent; Adult; Aged; Atherosclerosis; Biomarkers; Cardiovascular Diseases; Coronary Artery Disea | 2020 |
Lactobacillus plantarum 299v Supplementation Improves Vascular Endothelial Function and Reduces Inflammatory Biomarkers in Men With Stable Coronary Artery Disease.
Topics: Adipokines; Adult; Aged; Biomarkers; Coronary Artery Disease; Cytokines; Endothelium, Vascular; Fatt | 2018 |
25 other studies available for trimethyloxamine and Arteriosclerosis, Coronary
| Article | Year |
|---|---|
Gut microbiota-dependent metabolite trimethylamine N-oxide (TMAO) and cardiovascular risk in patients with suspected functionally relevant coronary artery disease (fCAD).
Topics: Betaine; Cardiovascular Diseases; Carnitine; Choline; Coronary Artery Disease; Gastrointestinal Micr | 2022 |
Serum Trimethylamine N-Oxide Levels Correlate with Metabolic Syndrome in Coronary Artery Disease Patients.
Topics: Biomarkers; C-Reactive Protein; Coronary Artery Disease; Glucose; Humans; Metabolic Syndrome; Methyl | 2022 |
Circulating trimethylamine N-oxide levels do not predict 10-year survival in patients with or without coronary heart disease.
Topics: Adult; Biomarkers; Coronary Artery Disease; Humans; Methylamines; Prospective Studies; Risk Factors; | 2022 |
Gut microbiota mediate vascular dysfunction in a murine model of sleep apnoea: effect of probiotics.
Topics: Animals; Coronary Artery Disease; Disease Models, Animal; Gastrointestinal Microbiome; Hypoxia; Mice | 2023 |
Association of Circulating Trimethylamine-N Oxide With Malnutrition and the Risk of Coronary Artery Disease in Patients With Maintenance Hemodialysis.
Topics: Cardiovascular Diseases; Coronary Artery Disease; Humans; Malnutrition; Oxides; Renal Dialysis | 2023 |
Plasma levels of trimethylamine-N-oxide can be increased with 'healthy' and 'unhealthy' diets and do not correlate with the extent of atherosclerosis but with plaque instability.
Topics: Animal Feed; Animals; Atherosclerosis; Bacteria; Biomarkers; Carotid Artery Diseases; Choline; Coron | 2021 |
Reply: TMAO Changes and Coronary Heart Disease Risk: Potential Impact and Study Considerations.
Topics: Coronary Artery Disease; Gastrointestinal Microbiome; Humans; Methylamines | 2020 |
Association of plasma trimethylamine N-Oxide level with healed culprit plaques examined by optical coherence tomography in patients with ST-Segment elevation myocardial infarction.
Topics: Aged; Biomarkers; Chromatography, Liquid; Coronary Artery Disease; Coronary Vessels; Female; Humans; | 2021 |
Plasma trimethylamine N-oxide (TMAO) levels predict future risk of coronary artery disease in apparently healthy individuals in the EPIC-Norfolk prospective population study.
Topics: Aged; Case-Control Studies; Choline; Coronary Artery Disease; Correlation of Data; Female; Gastroint | 2021 |
TMAO: a potential mediator of clopidogrel resistance.
Topics: Animals; Biomarkers; Blood Platelets; Clopidogrel; Coronary Artery Disease; Disease Models, Animal; | 2021 |
Compositional change of gut microbiome and osteocalcin expressing endothelial progenitor cells in patients with coronary artery disease.
Topics: AC133 Antigen; Adult; Aged; Antigens, CD34; Case-Control Studies; Cells, Cultured; Clostridiales; Co | 2021 |
Plasma trimethylamine N-oxide is associated with vulnerable plaque characteristics in CAD patients as assessed by optical coherence tomography.
Topics: Aged; Biomarkers; Coronary Artery Disease; Cross-Sectional Studies; Female; Humans; Male; Methylamin | 2018 |
Relation of Circulating Trimethylamine N-Oxide With Coronary Atherosclerotic Burden in Patients With ST-segment Elevation Myocardial Infarction.
Topics: Atherosclerosis; Biomarkers; Coronary Angiography; Coronary Artery Disease; Coronary Vessels; Female | 2019 |
Plasma Trimethylamine N-Oxide as a Novel Biomarker for Plaque Rupture in Patients With ST-Segment-Elevation Myocardial Infarction.
Topics: Aged; Biomarkers; Chromatography, High Pressure Liquid; Coronary Artery Disease; Cross-Sectional Stu | 2019 |
The carnitine-butyrobetaine-TMAO pathway after cardiac transplant: Impact on cardiac allograft vasculopathy and acute rejection.
Topics: Acute Disease; Adult; Aged; Betaine; Carnitine; Coronary Artery Disease; Cyclosporine; Everolimus; F | 2019 |
Plaque burden in HIV-infected patients is associated with serum intestinal microbiota-generated trimethylamine.
Topics: Choline; Coronary Artery Disease; Dysbiosis; Female; HIV Infections; Humans; Intestinal Diseases; Ma | 2015 |
Serum Trimethylamine-N-Oxide is Elevated in CKD and Correlates with Coronary Atherosclerosis Burden.
Topics: Aged; Coronary Artery Disease; Cross-Sectional Studies; Female; Humans; Kidney Transplantation; Male | 2016 |
Microbiota-Dependent Marker TMAO Is Elevated in Silent Ischemia but Is Not Associated With First-Time Myocardial Infarction in HIV Infection.
Topics: Adolescent; Adult; Aged; Biomarkers; Case-Control Studies; Cohort Studies; Coronary Artery Disease; | 2016 |
Associations among serum trimethylamine-N-oxide (TMAO) levels, kidney function and infarcted coronary artery number in patients undergoing cardiovascular surgery: a cross-sectional study.
Topics: Aged; Biomarkers; Cardiac Surgical Procedures; Chi-Square Distribution; Chromatography, High Pressur | 2016 |
Plasma Trimethylamine N-Oxide, a Gut Microbe-Generated Phosphatidylcholine Metabolite, Is Associated With Atherosclerotic Burden.
Topics: Aged; Biomarkers; Cohort Studies; Coronary Angiography; Coronary Artery Disease; Female; Humans; Mal | 2016 |
Intestinal Microbiota-Generated Metabolite Trimethylamine-N-Oxide and 5-Year Mortality Risk in Stable Coronary Artery Disease: The Contributory Role of Intestinal Microbiota in a COURAGE-Like Patient Cohort.
Topics: Aged; Cardiovascular Agents; Coronary Artery Disease; Coronary Stenosis; Epidemiologic Methods; Fema | 2016 |
Trimethylamine-N-oxide (TMAO) predicts fatal outcomes in community-acquired pneumonia patients without evident coronary artery disease.
Topics: Age Factors; Aged; Aged, 80 and over; Anti-Bacterial Agents; Cause of Death; Cerebrovascular Disorde | 2016 |
Coronary Plaque Characterization Assessed by Optical Coherence Tomography and Plasma Trimethylamine-N-oxide Levels in Patients With Coronary Artery Disease.
Topics: Biomarkers; Coronary Artery Disease; Disease Progression; Female; Humans; Male; Methylamines; Middle | 2016 |
Trimethylamine N-Oxide and Mortality Risk in Patients With Peripheral Artery Disease.
Topics: Aged; Carotid Stenosis; Cause of Death; Cohort Studies; Computed Tomography Angiography; Coronary An | 2016 |
Microbiota-Dependent Metabolite Trimethylamine N-Oxide and Coronary Artery Calcium in the Coronary Artery Risk Development in Young Adults Study (CARDIA).
Topics: Adult; Atherosclerosis; Black or African American; Carotid Intima-Media Thickness; Coronary Artery D | 2016 |