trimethyloxamine has been researched along with Amyotrophic Lateral Sclerosis in 2 studies
trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.
Amyotrophic Lateral Sclerosis: A degenerative disorder affecting upper MOTOR NEURONS in the brain and lower motor neurons in the brain stem and SPINAL CORD. Disease onset is usually after the age of 50 and the process is usually fatal within 3 to 6 years. Clinical manifestations include progressive weakness, atrophy, FASCICULATION, hyperreflexia, DYSARTHRIA, dysphagia, and eventual paralysis of respiratory function. Pathologic features include the replacement of motor neurons with fibrous ASTROCYTES and atrophy of anterior SPINAL NERVE ROOTS and corticospinal tracts. (From Adams et al., Principles of Neurology, 6th ed, pp1089-94)
| Excerpt | Relevance | Reference |
|---|---|---|
| "The aim of this study was to determine whether patients with amyotrophic lateral sclerosis (ALS) exhibit higher plasma levels of formaldehyde (FA) than controls, and to look for alterations in levels of FA precursors." | 7.96 | Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. ( Arachchige, BJ; Aylward, J; Henderson, R; Lee, A; McCombe, PA; Reed, S, 2020) |
| "The aim of this study was to determine whether patients with amyotrophic lateral sclerosis (ALS) exhibit higher plasma levels of formaldehyde (FA) than controls, and to look for alterations in levels of FA precursors." | 3.96 | Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels. ( Arachchige, BJ; Aylward, J; Henderson, R; Lee, A; McCombe, PA; Reed, S, 2020) |
| "The carnitine concentration was significantly higher in patients than in their spouses, while there were no significant differences in the concentrations of other metabolites." | 1.56 | Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis. ( Chen, L; Chen, Y; Fan, D; Zhao, M; Zheng, L, 2020) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lee, A | 1 |
| Arachchige, BJ | 1 |
| Reed, S | 1 |
| Henderson, R | 1 |
| Aylward, J | 1 |
| McCombe, PA | 1 |
| Chen, L | 1 |
| Chen, Y | 1 |
| Zhao, M | 1 |
| Zheng, L | 1 |
| Fan, D | 1 |
2 other studies available for trimethyloxamine and Amyotrophic Lateral Sclerosis
| Article | Year |
|---|---|
Plasma from some patients with amyotrophic lateral sclerosis exhibits elevated formaldehyde levels.
Topics: Aged; Amyotrophic Lateral Sclerosis; Biomarkers; Female; Formaldehyde; Humans; Male; Methylamines; M | 2020 |
Changes in the concentrations of trimethylamine N-oxide (TMAO) and its precursors in patients with amyotrophic lateral sclerosis.
Topics: Amyotrophic Lateral Sclerosis; Betaine; Carnitine; Choline; Female; Gastrointestinal Microbiome; Hum | 2020 |