Page last updated: 2024-10-20

trimethyloxamine and Acute Coronary Syndrome

trimethyloxamine has been researched along with Acute Coronary Syndrome in 9 studies

trimethyloxamine: used in manufacture of quaternary ammonium cpds; insect attractant; warming agent for gas; oxidant; structure
trimethylamine N-oxide : A tertiary amine oxide resulting from the oxidation of the amino group of trimethylamine.

Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.

Research Excerpts

ExcerptRelevanceReference
"Trimethyllysine (TML) serves as a nutrient precursor of the gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) and is associated with incident cardiovascular (CV) events in stable subjects."5.51Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes. ( Chung, YM; Gu, X; Hazen, BJ; Hazen, SL; Hurd, AG; Levison, BS; Li, L; Li, XS; Lüscher, TF; Mach, F; Matter, CM; Nanchen, D; Nissen, SE; Obeid, S; Pratt, A; Räber, L; Tang, WHW; Wang, Z; Wu, Y, 2019)
"ACS and incident post-STEMI MACE may be associated with the gut bacteria choline metabolite TMAO."1.56Gut microbial taxa as potential predictive biomarkers for acute coronary syndrome and post-STEMI cardiovascular events. ( Dou, J; Gao, J; Liu, Y; Ma, J; Ren, M; Wang, J; Wang, JX; Yan, KT; Zhang, X, 2020)
"Trimethyllysine (TML) serves as a nutrient precursor of the gut microbiota-derived metabolite trimethylamine N-oxide (TMAO) and is associated with incident cardiovascular (CV) events in stable subjects."1.51Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes. ( Chung, YM; Gu, X; Hazen, BJ; Hazen, SL; Hurd, AG; Levison, BS; Li, L; Li, XS; Lüscher, TF; Mach, F; Matter, CM; Nanchen, D; Nissen, SE; Obeid, S; Pratt, A; Räber, L; Tang, WHW; Wang, Z; Wu, Y, 2019)
"Betaine is a major osmolyte, also important in methyl group metabolism."1.40Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study. ( Atkinson, W; Bellamy, D; Chambers, ST; Elmslie, JL; Frampton, CM; George, PM; Ho, M; Lever, M; McEntyre, CJ; Molyneux, SL; Richards, AM; Slow, S; Troughton, RW; Young, JM, 2014)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's6 (66.67)24.3611
2020's3 (33.33)2.80

Authors

AuthorsStudies
Konieczny, RA1
Żurawska-Płaksej, E1
Kaaz, K1
Czapor-Irzabek, H1
Bombała, W1
Mysiak, A1
Kuliczkowski, W1
Gao, J1
Yan, KT1
Wang, JX1
Dou, J1
Wang, J1
Ren, M1
Ma, J1
Zhang, X1
Liu, Y1
Tascanov, MB1
Tanriverdi, Z1
Gungoren, F1
Besli, F1
Erkus, ME1
Koyuncu, I1
Gonel, A1
Genc Tapar, G1
Li, XS2
Obeid, S2
Wang, Z2
Hazen, BJ1
Li, L2
Wu, Y2
Hurd, AG1
Gu, X1
Pratt, A1
Levison, BS1
Chung, YM2
Nissen, SE1
Tang, WHW1
Mach, F2
Räber, L2
Nanchen, D2
Matter, CM2
Lüscher, TF2
Hazen, SL2
Schiattarella, GG1
Trimarco, B1
Lever, M1
George, PM1
Slow, S1
Bellamy, D1
Young, JM1
Ho, M1
McEntyre, CJ1
Elmslie, JL1
Atkinson, W1
Molyneux, SL1
Troughton, RW1
Frampton, CM1
Richards, AM1
Chambers, ST1
Klingenberg, R1
Gencer, B1
Windecker, S1
Rodondi, N1
Muller, O1
Miranda, MX1
Alamri, HS1
Gogonea, V1
Tang, WH1
Fernández-Ruiz, I1
Trøseid, M1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effects of a Whole Food Based Nutritional Formulation on Trimethylamine N-oxide and Cardiometabolic Endpoints in Healthy Adults.[NCT05795946]45 participants (Anticipated)Interventional2023-04-15Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

9 other studies available for trimethyloxamine and Acute Coronary Syndrome

ArticleYear
Citrulline and long-term mortality in patients with cardiovascular disease.
    Advances in clinical and experimental medicine : official organ Wroclaw Medical University, 2022, Volume: 31, Issue:10

    Topics: Acute Coronary Syndrome; Biomarkers; Cardiovascular Diseases; Citrulline; Female; Humans; Male; Midd

2022
Gut microbial taxa as potential predictive biomarkers for acute coronary syndrome and post-STEMI cardiovascular events.
    Scientific reports, 2020, 02-14, Volume: 10, Issue:1

    Topics: Acute Coronary Syndrome; Adult; Biomarkers; Female; Gastrointestinal Microbiome; Humans; Male; Methy

2020
Comparisons of microbiota-generated metabolites in patients with young and elderly acute coronary syndrome.
    Anatolian journal of cardiology, 2020, Volume: 24, Issue:3

    Topics: Acute Coronary Syndrome; Adult; Age Factors; Aged; Biomarkers; Choline; Female; Humans; Male; Methyl

2020
Trimethyllysine, a trimethylamine N-oxide precursor, provides near- and long-term prognostic value in patients presenting with acute coronary syndromes.
    European heart journal, 2019, 08-21, Volume: 40, Issue:32

    Topics: Acute Coronary Syndrome; Aged; Female; Humans; Lysine; Male; Methylamines; Middle Aged; Prognosis; P

2019
Microbial metabolites as predictive biomarkers: a paradigm shift for cardiovascular risk stratification.
    European heart journal, 2019, 08-21, Volume: 40, Issue:32

    Topics: Acute Coronary Syndrome; Biomarkers; Cardiovascular Diseases; Humans; Lysine; Methylamines; Prognosi

2019
Betaine and Trimethylamine-N-Oxide as Predictors of Cardiovascular Outcomes Show Different Patterns in Diabetes Mellitus: An Observational Study.
    PloS one, 2014, Volume: 9, Issue:12

    Topics: Acute Coronary Syndrome; Aged; Aged, 80 and over; Betaine; Biomarkers; Cardiovascular Diseases; Case

2014
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors.
    European heart journal, 2017, Mar-14, Volume: 38, Issue:11

    Topics: Acute Coronary Syndrome; Biomarkers; Cardiotonic Agents; Case-Control Studies; Female; Gastrointesti

2017
Acute coronary syndromes: Microbial-dependent TMAO as a prognostic marker in ACS.
    Nature reviews. Cardiology, 2017, Volume: 14, Issue:3

    Topics: Acute Coronary Syndrome; Gastrointestinal Microbiome; Humans; Methylamines; Prognosis; Risk Factors

2017
Gut microbiota and acute coronary syndromes: ready for use in the emergency room?
    European heart journal, 2017, 03-14, Volume: 38, Issue:11

    Topics: Acute Coronary Syndrome; Emergency Service, Hospital; Gastrointestinal Microbiome; Humans; Methylami

2017