trimethylamine has been researched along with Renal Insufficiency, Chronic in 14 studies
Renal Insufficiency, Chronic: Conditions in which the KIDNEYS perform below the normal level for more than three months. Chronic kidney insufficiency is classified by five stages according to the decline in GLOMERULAR FILTRATION RATE and the degree of kidney damage (as measured by the level of PROTEINURIA). The most severe form is the end-stage renal disease (CHRONIC KIDNEY FAILURE). (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota." | 5.91 | Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023) |
| " Trimethylamine-N-oxide (TMAO) and trimethylamine (TMA) are gut microbiota-derived metabolites, and both are known uraemic toxins that are implicated in CKD, atherosclerosis, colorectal cancer and cardiovascular risk." | 4.02 | Rapid Detection of Gut Microbial Metabolite Trimethylamine N-Oxide for Chronic Kidney Disease Prevention. ( Chang, YC; Chu, YH; Tain, YL; Wang, CC; Wang, CH; Yang, HW, 2021) |
| "Choline is a water-soluble nutrient essential for human life." | 2.66 | The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases. ( Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A, 2020) |
| "Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota." | 1.91 | Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023) |
| "Trimethylamine was used as a probe substrate to assess FMO activity." | 1.51 | Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease. ( Leblond, FA; Nolin, TD; Pichette, V; Prokopienko, AJ; Schrum, DP; Stubbs, JR; West, RE, 2019) |
| "Isoprene was detected in the range 57." | 1.39 | Detection of potential chronic kidney disease markers in breath using gas chromatography with mass-spectral detection coupled with thermal desorption method. ( Amann, A; Faber, J; Grabowska-Polanowska, B; Miarka, P; Pietrzycka, A; Skowron, M; Sliwka, I, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (57.14) | 24.3611 |
| 2020's | 6 (42.86) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, YC | 1 |
| Chu, YH | 1 |
| Wang, CC | 1 |
| Wang, CH | 1 |
| Tain, YL | 2 |
| Yang, HW | 1 |
| Chen, G | 1 |
| He, L | 1 |
| Dou, X | 1 |
| Liu, T | 1 |
| Chang-Chien, GP | 1 |
| Lin, S | 1 |
| Hou, CY | 1 |
| Hsu, CN | 1 |
| Yong, C | 1 |
| Huang, GS | 1 |
| Ge, HW | 1 |
| Sun, QM | 1 |
| Gao, K | 1 |
| Zhou, EC | 1 |
| Craven, H | 1 |
| Erlandsson, H | 1 |
| McGuinness, D | 1 |
| McGuinness, DH | 1 |
| Mafra, D | 2 |
| Ijaz, UZ | 1 |
| Bergman, P | 2 |
| Shiels, PG | 1 |
| Stenvinkel, P | 2 |
| Pelletier, CC | 1 |
| Croyal, M | 1 |
| Ene, L | 1 |
| Aguesse, A | 1 |
| Billon-Crossouard, S | 1 |
| Krempf, M | 1 |
| Lemoine, S | 1 |
| Guebre-Egziabher, F | 1 |
| Juillard, L | 1 |
| Soulage, CO | 1 |
| Prokopienko, AJ | 1 |
| West, RE | 1 |
| Schrum, DP | 1 |
| Stubbs, JR | 1 |
| Leblond, FA | 1 |
| Pichette, V | 1 |
| Nolin, TD | 1 |
| Dai, Q | 1 |
| Zhang, H | 1 |
| Liu, Y | 1 |
| Arias, N | 1 |
| Arboleya, S | 1 |
| Allison, J | 1 |
| Kaliszewska, A | 1 |
| Higarza, SG | 1 |
| Gueimonde, M | 1 |
| Arias, JL | 1 |
| Shen, TD | 1 |
| Cheung, KWK | 1 |
| Hsueh, CH | 1 |
| Zhao, P | 1 |
| Meyer, TW | 1 |
| Zhang, L | 1 |
| Huang, SM | 1 |
| Giacomini, KM | 1 |
| Grabowska-Polanowska, B | 2 |
| Skowron, M | 2 |
| Miarka, P | 2 |
| Pietrzycka, A | 2 |
| Śliwka, I | 2 |
| Borges, NA | 1 |
| Qureshi, AR | 1 |
| Lindholm, B | 1 |
| Moraes, C | 1 |
| Stockler-Pinto, MB | 1 |
| Faber, J | 1 |
| Amann, A | 1 |
4 reviews available for trimethylamine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Association of Trimethylamine-N-Oxide Levels with Risk of Cardiovascular Disease and Mortality among Elderly Subjects: A Systematic Review and Meta-Analysis.
Topics: Aged; Biomarkers; Cardiovascular Diseases; Heart Failure; Humans; Methylamines; Oxides; Prospective | 2022 |
[Effect of traditional Chinese medicine in attenuating chronic kidney disease and its complications by regulating gut microbiota-derived metabolite trimethylamine N-oxide: a review].
Topics: Gastrointestinal Microbiome; Humans; Medicine, Chinese Traditional; Renal Insufficiency, Chronic | 2023 |
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestina | 2020 |
Diet and Gut Microbiota in Health and Disease.
Topics: Animals; Bacteria; Choline; Diet; Dietary Carbohydrates; Dysbiosis; Fecal Microbiota Transplantation | 2017 |
1 trial available for trimethylamine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Effects of Probiotic Supplementation on Trimethylamine-N-Oxide Plasma Levels in Hemodialysis Patients: a Pilot Study.
Topics: Adult; Aged; Bifidobacterium longum; Dietary Supplements; Double-Blind Method; Female; Humans; Lacto | 2019 |
9 other studies available for trimethylamine and Renal Insufficiency, Chronic
| Article | Year |
|---|---|
Rapid Detection of Gut Microbial Metabolite Trimethylamine N-Oxide for Chronic Kidney Disease Prevention.
Topics: Atherosclerosis; Gastrointestinal Microbiome; Humans; Manganese Compounds; Methylamines; Oxides; Ren | 2021 |
Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension.
Topics: Animals; Female; Humans; Hypertension; Hypertrophy; Methylamines; Oxides; Pregnancy; Rats; Renal Ins | 2023 |
A normative microbiome is not restored following kidney transplantation.
Topics: Dysbiosis; Gastrointestinal Microbiome; Humans; Kidney Transplantation; Microbiota; Renal Insufficie | 2023 |
Elevation of Trimethylamine-N-Oxide in Chronic Kidney Disease: Contribution of Decreased Glomerular Filtration Rate.
Topics: Adult; Betaine; Choline; Creatinine; Female; Gastrointestinal Microbiome; Glomerular Filtration Rate | 2019 |
Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease.
Topics: Activation, Metabolic; Animals; Blood Urea Nitrogen; Creatinine; Cytochrome P-450 CYP1A2; Disease Mo | 2019 |
[Trimethylamine-N-oxide and cardiovascular events in chronic kidney disease].
Topics: Biomarkers; Cardiovascular Diseases; Humans; Methylamines; Oxides; Renal Insufficiency, Chronic | 2019 |
The Effect of Uremic Solutes on the Organic Cation Transporter 2.
Topics: Biological Transport; Dimethylamines; Glomerular Filtration Rate; Glucuronates; Glutathione Disulfid | 2017 |
The application of chromatographic breath analysis in the search of volatile biomarkers of chronic kidney disease and coexisting type 2 diabetes mellitus.
Topics: Acetone; Adult; Biomarkers; Butadienes; Case-Control Studies; Diabetes Mellitus, Type 2; Exhalation; | 2017 |
Detection of potential chronic kidney disease markers in breath using gas chromatography with mass-spectral detection coupled with thermal desorption method.
Topics: Adult; Aged; Aged, 80 and over; Biomarkers; Breath Tests; Butadienes; Case-Control Studies; Female; | 2013 |