Page last updated: 2024-10-20

trimethylamine and Pregnancy

trimethylamine has been researched along with Pregnancy in 14 studies

Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.

Research Excerpts

ExcerptRelevanceReference
"Gut microbiota-dependent metabolites, in particular trimethylamine (TMA), are linked to hypertension."7.96Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure. ( Chan, JYH; Chang-Chien, GP; Hou, CY; Hsu, CN; Lee, WC; Lin, S; Tain, YL; Wu, KLH; Yu, HR, 2020)
"Alterations of gut metabolites, such as SCFAs and trimethylamine (TMA), and microbial composition are associated with the development of hypertension."7.91Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2019)
"Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota."5.91Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023)
"Gut microbiota-dependent metabolites, in particular trimethylamine (TMA), are linked to hypertension."3.96Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure. ( Chan, JYH; Chang-Chien, GP; Hou, CY; Hsu, CN; Lee, WC; Lin, S; Tain, YL; Wu, KLH; Yu, HR, 2020)
"Alterations of gut metabolites, such as SCFAs and trimethylamine (TMA), and microbial composition are associated with the development of hypertension."3.91Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2019)
"Offspring hypertension is associated with increases in the plasma TMAO concentration and oxidative stress and shifts in gut microbiota."1.91Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension. ( Chang-Chien, GP; Hou, CY; Hsu, CN; Lin, S; Tain, YL, 2023)
"Triclosan is a broad-spectrum antimicrobial, and was thought to affect intrauterine development, but the mechanism remains unclear."1.72Multiple mediation effects on association between prenatal triclosan exposure and birth outcomes. ( Cao, Y; Chang, X; Dai, Y; Guo, J; Liang, W; Lu, D; Lv, S; Qi, X; Wang, Z; Wu, C; Zhang, J; Zhang, L; Zhou, Z, 2022)
"Trimethylamine (TMA) is an aliphatic amine, and its blood levels can increase after ingestion of certain foods, such as fish, and during disease states, such as chronic renal failure."1.28Teratogenic and macromolecular synthesis inhibitory effects of trimethylamine on mouse embryos in culture. ( Guest, I; Varma, DR, 1992)
" Although methylamines exert several toxic effects including inhibition of protein turnover and oocyte RNA synthesis, their reproductive toxicity has not been investigated."1.28Developmental toxicity of methylamines in mice. ( Guest, I; Varma, DR, 1991)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (35.71)18.2507
2000's1 (7.14)29.6817
2010's3 (21.43)24.3611
2020's5 (35.71)2.80

Authors

AuthorsStudies
Zhang, J1
Wang, Z1
Dai, Y1
Zhang, L1
Guo, J1
Lv, S1
Qi, X1
Lu, D1
Liang, W1
Cao, Y1
Wu, C1
Chang, X1
Zhou, Z1
Tain, YL3
Chang-Chien, GP3
Lin, S3
Hou, CY3
Hsu, CN3
Banks, M1
Amirghasemi, F1
Mitchell, E1
Mousavi, MPS1
Nagy, RA1
Homminga, I1
Jia, C1
Liu, F1
Anderson, JLC1
Hoek, A1
Tietge, UJF1
Chan, JYH1
Yu, HR1
Lee, WC1
Wu, KLH1
Palinski, W1
Luthra, G1
Vuckovic, I1
Bangdiwala, A1
Gray, H1
Redmon, JB1
Barrett, ES1
Sathyanarayana, S1
Nguyen, RHN1
Swan, SH1
Zhang, S1
Dzeja, P1
Macura, SI1
Nair, KS1
Heaton, RC2
Wray, S2
Eisner, DA1
Guest, I3
Varma, DR3
Squirrell, JM1
Lane, M1
Bavister, BD1
Taggart, MJ1

Other Studies

14 other studies available for trimethylamine and Pregnancy

ArticleYear
Multiple mediation effects on association between prenatal triclosan exposure and birth outcomes.
    Environmental research, 2022, Volume: 215, Issue:Pt 1

    Topics: Acetylcarnitine; Bayes Theorem; Betaine; Choline; Cohort Studies; Estradiol; Female; Humans; Leptin;

2022
Iodomethylcholine Inhibits Trimethylamine-N-Oxide Production and Averts Maternal Chronic Kidney Disease-Programmed Offspring Hypertension.
    International journal of molecular sciences, 2023, Jan-09, Volume: 24, Issue:2

    Topics: Animals; Female; Humans; Hypertension; Hypertrophy; Methylamines; Oxides; Pregnancy; Rats; Renal Ins

2023
Home-Based Electrochemical Rapid Sensor (HERS): A Diagnostic Tool for Bacterial Vaginosis.
    Sensors (Basel, Switzerland), 2023, Feb-08, Volume: 23, Issue:4

    Topics: Animals; Body Fluids; Borates; Female; Flowers; Humans; Pregnancy; Vaginosis, Bacterial

2023
Trimethylamine-N-oxide is present in human follicular fluid and is a negative predictor of embryo quality.
    Human reproduction (Oxford, England), 2020, 01-01, Volume: 35, Issue:1

    Topics: Cross-Sectional Studies; Female; Fertilization in Vitro; Follicular Fluid; Humans; Methylamines; Net

2020
Targeting on Gut Microbiota-Derived Metabolite Trimethylamine to Protect Adult Male Rat Offspring against Hypertension Programmed by Combined Maternal High-Fructose Intake and Dioxin Exposure.
    International journal of molecular sciences, 2020, Jul-31, Volume: 21, Issue:15

    Topics: Animals; Diet, Carbohydrate Loading; Dioxins; Female; Fructose; Gastrointestinal Microbiome; Hyperte

2020
A Gut Feeling About Developmental Programming Mechanisms: Trimethylamine-N-Oxide May Enhance Atherosclerosis in Offspring of Hypercholesterolemic Mice.
    Arteriosclerosis, thrombosis, and vascular biology, 2017, Volume: 37, Issue:11

    Topics: Animals; Atherosclerosis; Bile Acids and Salts; Female; Hypercholesterolemia; Methylamines; Mice; Ox

2017
First and second trimester urinary metabolic profiles and fetal growth restriction: an exploratory nested case-control study within the infant development and environment study.
    BMC pregnancy and childbirth, 2018, 02-08, Volume: 18, Issue:1

    Topics: Acetates; Adult; Case-Control Studies; Female; Fetal Growth Retardation; Formates; Gestational Age;

2018
Targeting on Gut Microbial Metabolite Trimethylamine-N-Oxide and Short-Chain Fatty Acid to Prevent Maternal High-Fructose-Diet-Induced Developmental Programming of Hypertension in Adult Male Offspring.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:18

    Topics: Acetates; Animals; Blood Pressure; Dietary Supplements; Fatty Acids, Volatile; Female; Fructose; Gas

2019
Effects of metabolic inhibition and changes of intracellular pH on potassium permeability and contraction of rat uterus.
    The Journal of physiology, 1993, Volume: 465

    Topics: Adenosine Triphosphate; Animals; Antimetabolites; Cell Hypoxia; Cyanides; Female; Glyburide; Hydroge

1993
Selective growth inhibition of the male progeny of mice treated with trimethylamine during pregnancy.
    Canadian journal of physiology and pharmacology, 1993, Volume: 71, Issue:2

    Topics: Animals; Birth Weight; Body Weight; Brain; DNA; Dose-Response Relationship, Drug; Embryonic and Feta

1993
Altering intracellular pH disrupts development and cellular organization in preimplantation hamster embryos.
    Biology of reproduction, 2001, Volume: 64, Issue:6

    Topics: Actin Cytoskeleton; Animals; Blastomeres; Cell Nucleus; Cricetinae; Culture Media; Culture Technique

2001
Teratogenic and macromolecular synthesis inhibitory effects of trimethylamine on mouse embryos in culture.
    Journal of toxicology and environmental health, 1992, Volume: 36, Issue:1

    Topics: Abnormalities, Drug-Induced; Animals; Ascorbic Acid; Culture Techniques; DNA; Embryo, Mammalian; Emb

1992
The effects of intracellular and extracellular alkalinization on contractions of the isolated rat uterus.
    Pflugers Archiv : European journal of physiology, 1992, Volume: 422, Issue:1

    Topics: Alkalies; Ammonia; Animals; Extracellular Space; Female; Intracellular Membranes; Methylamines; Pota

1992
Developmental toxicity of methylamines in mice.
    Journal of toxicology and environmental health, 1991, Volume: 32, Issue:3

    Topics: Animals; Culture Techniques; Dimethylamines; Dose-Response Relationship, Drug; Embryo, Mammalian; Em

1991