Page last updated: 2024-10-20

trimethylamine and Obesity

trimethylamine has been researched along with Obesity in 5 studies

Obesity: A status with BODY WEIGHT that is grossly above the recommended standards, usually due to accumulation of excess FATS in the body. The standards may vary with age, sex, genetic or cultural background. In the BODY MASS INDEX, a BMI greater than 30.0 kg/m2 is considered obese, and a BMI greater than 40.0 kg/m2 is considered morbidly obese (MORBID OBESITY).

Research Excerpts

ExcerptRelevanceReference
"Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the human host."5.72Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms. ( Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B, 2022)
"Obesity has repeatedly been linked to reorganization of the gut microbiome, yet to this point obesity therapeutics have been targeted exclusively toward the human host."1.72Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms. ( Allen, FM; Anderson, JT; Armstrong, AR; Banerjee, R; Brown, AL; Brown, JM; Buffa, JA; Burrows, A; Cook, K; Ferguson, D; Finney, C; Fung, KK; Garcia-Garcia, JC; Gliniak, CM; Goudarzi, M; Gromovsky, AD; Hazen, SL; Helsley, RN; Horak, A; Keshavarzian, A; Lusis, AJ; Mak, TD; Massey, W; McMillan, A; Mehrabian, M; Neumann, C; Orabi, D; Osborn, LJ; Sangwan, N; Schugar, RC; Swanson, G; Wang, Z; Willard, B, 2022)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's1 (20.00)24.3611
2020's3 (60.00)2.80

Authors

AuthorsStudies
Schugar, RC1
Gliniak, CM1
Osborn, LJ1
Massey, W1
Sangwan, N1
Horak, A1
Banerjee, R1
Orabi, D1
Helsley, RN1
Brown, AL1
Burrows, A1
Finney, C1
Fung, KK1
Allen, FM1
Ferguson, D1
Gromovsky, AD1
Neumann, C1
Cook, K1
McMillan, A1
Buffa, JA1
Anderson, JT1
Mehrabian, M1
Goudarzi, M1
Willard, B1
Mak, TD1
Armstrong, AR1
Swanson, G1
Keshavarzian, A1
Garcia-Garcia, JC1
Wang, Z1
Lusis, AJ1
Hazen, SL1
Brown, JM1
Rehman, A1
Tyree, SM1
Fehlbaum, S1
DunnGalvin, G1
Panagos, CG1
Guy, B1
Patel, S1
Dinan, TG1
Duttaroy, AK1
Duss, R1
Steinert, RE1
Argyridou, S1
Davies, MJ1
Biddle, GJH1
Bernieh, D1
Suzuki, T1
Dawkins, NP1
Rowlands, AV1
Khunti, K1
Smith, AC1
Yates, T1
Angiletta, CJ1
Griffin, LE1
Steele, CN1
Baer, DJ1
Novotny, JA1
Davy, KP1
Neilson, AP1
Eisen, EJ1
Jones, EE1
Rajendran, KG1
Hall, IH1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effects of an 8-week Vegan Diet on Trimethylamine-N-Oxide (TMAO) Levels and Post-challenge Glucose Levels in Individuals With Dysglycaemia (The Plant Your Health Study)[NCT03315988]28 participants (Actual)Interventional2017-10-04Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for trimethylamine and Obesity

ArticleYear
A water-soluble tomato extract rich in secondary plant metabolites lowers trimethylamine-n-oxide and modulates gut microbiota: a randomized, double-blind, placebo-controlled cross-over study in overweight and obese adults.
    The Journal of nutrition, 2023, Volume: 153, Issue:1

    Topics: Adult; Cross-Over Studies; Gastrointestinal Microbiome; Humans; Methylamines; Obesity; Overweight; O

2023
Evaluation of an 8-Week Vegan Diet on Plasma Trimethylamine-N-Oxide and Postchallenge Glucose in Adults with Dysglycemia or Obesity.
    The Journal of nutrition, 2021, 07-01, Volume: 151, Issue:7

    Topics: Adult; Diet, Vegan; Female; Glucose; Humans; Male; Methylamines; Obesity; Oxides; Prospective Studie

2021
Impact of short-term flavanol supplementation on fasting plasma trimethylamine N-oxide concentrations in obese adults.
    Food & function, 2018, Oct-17, Volume: 9, Issue:10

    Topics: Adult; Body Mass Index; Chocolate; Fasting; Female; Flavonoids; Humans; Male; Methylamines; Middle A

2018

Other Studies

2 other studies available for trimethylamine and Obesity

ArticleYear
Gut microbe-targeted choline trimethylamine lyase inhibition improves obesity via rewiring of host circadian rhythms.
    eLife, 2022, 01-24, Volume: 11

    Topics: Animals; Choline; Circadian Rhythm; Diet, High-Fat; Enzyme Inhibitors; Gastrointestinal Microbiome;

2022
Effect of trimethylamine-carbomethoxyborane on growth traits and lipid metabolism in lines of mice selected for high and low fat content.
    Growth, development, and aging : GDA, 1996,Spring, Volume: 60, Issue:1

    Topics: Adipose Tissue; Animals; Animals, Newborn; Body Composition; Boranes; Cholesterol; Cholesterol 7-alp

1996