trimethylamine has been researched along with Metabolism, Inborn Errors in 76 studies
Metabolism, Inborn Errors: Errors in metabolic processes resulting from inborn genetic mutations that are inherited or acquired in utero.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The fish odour syndrome was diagnosed in 11 subjects: the percentage of total trimethylamine excreted in their urine samples that was oxidised to trimethylamine N-oxide was < 55% under normal dietary conditions and < 25% after oral challenge with trimethylamine (in normal subjects > 80% of trimethylamine was N-oxidised)." | 5.07 | The fish odour syndrome: biochemical, familial, and clinical aspects. ( Ayesh, R; Mitchell, SC; Smith, RL; Zhang, A, 1993) |
| "An oral trimethylamine challenge test has been used to confirm the heterozygous status of patients with 'fish-odour syndrome'." | 3.69 | Fish odour syndrome: verification of carrier detection test. ( Mitchell, S; Smith, R; Zhang, AQ, 1995) |
| " Beginning with a single propositus, who had been previously diagnosed at the age of 10 as suffering from trimethylaminuria (fish-odour syndrome), both her parents and two sisters were investigated biochemically with respect to their ability to N-oxidize trimethylamine (TMA), both when derived from the diet and when administered exogenously." | 3.67 | Trimethylaminuria ('fish-odour syndrome'): a study of an affected family. ( Al-Waiz, M; Ayesh, R; Idle, JR; Mitchell, SC; Smith, RL, 1988) |
| "Trimethylamine (TMA) is a volatile, foul-smelling, diet-derived amine, primarily generated in the colon and metabolized in the liver to its odorless N-oxide (TMAO)." | 2.66 | Treatments of trimethylaminuria: where we are and where we might be heading. ( Leroux, JC; Schmidt, AC, 2020) |
| "Trimethylamine (TMA) is a tertiary amine with a characteristic fishy odour." | 2.53 | The complex metabolism of trimethylamine in humans: endogenous and exogenous sources. ( Bhargava, B; Chhibber-Goel, J; Gaur, A; Parakh, N; Sharma, A; Singhal, V, 2016) |
| "Riboflavin is an effective treatment." | 1.62 | Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin. ( Alibrandi, S; D'Angelo, R; Donato, L; Giofrè, SV; Rao, G; Scimone, C; Sidoti, A, 2021) |
| "Trimethylamine N-oxygenation was catalyzed largely by FMO3 and not by FMO1 or FMO5." | 1.37 | Developmental variations in metabolic capacity of flavin-containing mono-oxygenase 3 in childhood. ( Cashman, JR; Denton, T; Kozono, M; Leeder, JS; Shimizu, M; Yamazaki, H, 2011) |
| "Trimethylamine (TMA) is a volatile substance produced in the gut, absorbed into the blood and further metabolized by healthy individuals into trimethylamine-N-oxide (TMAO) by TMA-oxidase and then excreted in urine." | 1.33 | Diagnosis of suspected trimethylaminuria by NMR spectroscopy. ( Arêas, JA; Lanfer-Marquez, UM; Podadera, P; Sipahi, AM, 2005) |
| "Trimethylamine itself has the powerful aroma of rotting fish, and this confers upon the sufferer a highly objectionable body odor, which can be destructive to the personal, social, and work life of the affected individual." | 1.31 | Trimethylaminuria: the fish malodor syndrome. ( Mitchell, SC; Smith, RL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (6.58) | 18.7374 |
| 1990's | 28 (36.84) | 18.2507 |
| 2000's | 23 (30.26) | 29.6817 |
| 2010's | 13 (17.11) | 24.3611 |
| 2020's | 7 (9.21) | 2.80 |
| Authors | Studies |
|---|---|
| Alibrandi, S | 2 |
| Nicita, F | 1 |
| Donato, L | 2 |
| Scimone, C | 3 |
| Rinaldi, C | 2 |
| D'Angelo, R | 3 |
| Sidoti, A | 3 |
| Shimizu, M | 7 |
| Yamamoto, A | 1 |
| Makiguchi, M | 1 |
| Shimamura, E | 1 |
| Yokota, Y | 1 |
| Harano, M | 1 |
| Yamazaki, H | 8 |
| Fadhlaoui, K | 1 |
| Arnal, ME | 1 |
| Martineau, M | 1 |
| Camponova, P | 1 |
| Ollivier, B | 1 |
| O'Toole, PW | 1 |
| Brugère, JF | 1 |
| Schmidt, AC | 1 |
| Leroux, JC | 1 |
| Dionisio, L | 1 |
| Stupniki, S | 1 |
| Oyama, S | 1 |
| Aztiria, E | 1 |
| Alda, M | 1 |
| Spitzmaul, G | 1 |
| Giofrè, SV | 1 |
| Rao, G | 1 |
| Veyrat-Durebex, C | 1 |
| Benz-de-Bretagne, I | 1 |
| Clavier, V | 1 |
| Bruno, C | 1 |
| Andres, CR | 1 |
| Antar, C | 1 |
| Hennart, B | 1 |
| Maillot, F | 1 |
| Nadal-Desbarats, L | 1 |
| Blasco, H | 1 |
| Gao, C | 1 |
| Catucci, G | 1 |
| Castrignanò, S | 1 |
| Gilardi, G | 1 |
| Sadeghi, SJ | 1 |
| Kılıç, M | 1 |
| McConnell, A | 1 |
| Bonnin, R | 1 |
| Bellis, W | 1 |
| Tarchichi, T | 1 |
| Wong, K | 1 |
| Fisher, MM | 1 |
| Palomo, P | 1 |
| Zapata, F | 1 |
| Bawle, EV | 1 |
| Esposito, T | 1 |
| Bruschetta, D | 1 |
| Ruggeri, A | 1 |
| Oliveira, A | 1 |
| Faria, A | 1 |
| Oliva, M | 1 |
| Chhibber-Goel, J | 1 |
| Gaur, A | 1 |
| Singhal, V | 1 |
| Parakh, N | 1 |
| Bhargava, B | 1 |
| Sharma, A | 1 |
| Guo, Y | 1 |
| Hwang, LD | 1 |
| Li, J | 1 |
| Eades, J | 1 |
| Yu, CW | 1 |
| Mansfield, C | 1 |
| Burdick-Will, A | 1 |
| Chang, X | 1 |
| Chen, Y | 1 |
| Duke, FF | 1 |
| Zhang, J | 3 |
| Fakharzadeh, S | 1 |
| Fennessey, P | 1 |
| Keating, BJ | 1 |
| Jiang, H | 1 |
| Hakonarson, H | 1 |
| Reed, DR | 1 |
| Preti, G | 3 |
| Montoya Alvarez, T | 1 |
| Díaz Guardiola, P | 1 |
| Elviro, R | 1 |
| Wevers, R | 1 |
| Astuto, M | 1 |
| Arena, G | 1 |
| Ferla, L | 1 |
| Murabito, P | 1 |
| Gullo, A | 1 |
| Nanayakkara, PW | 1 |
| Meijboom, M | 1 |
| Kramer, MH | 1 |
| Wevers, RA | 1 |
| Jakobs, C | 1 |
| Denton, T | 1 |
| Kozono, M | 1 |
| Cashman, JR | 9 |
| Leeder, JS | 1 |
| Li, M | 1 |
| Al-Sarraf, A | 1 |
| Sinclair, G | 1 |
| Frohlich, J | 1 |
| Kobayashi, Y | 1 |
| Hayashi, S | 1 |
| Aoki, Y | 1 |
| Lundén, A | 1 |
| Marklund, S | 1 |
| Gustafsson, V | 1 |
| Andersson, L | 1 |
| Fraser-Andrews, EA | 1 |
| Manning, NJ | 1 |
| Ashton, GH | 1 |
| Eldridge, P | 1 |
| McGrath, J | 1 |
| Menagé, Hdu P | 1 |
| Camp, K | 1 |
| Fakharzadeh, SS | 1 |
| Fennessey, PV | 1 |
| Hines, RN | 1 |
| Mamer, OA | 3 |
| Mitchell, SC | 10 |
| Nguyen, GP | 1 |
| Schlenk, D | 1 |
| Smith, RL | 12 |
| Tjoa, SS | 1 |
| Williams, DE | 1 |
| Yannicelli, S | 1 |
| Pardini, RS | 1 |
| Sapien, RE | 1 |
| Tran, Q | 1 |
| Lattard, V | 1 |
| Hernandez, D | 1 |
| Addou, S | 1 |
| Lee, D | 1 |
| Orengo, C | 1 |
| Shephard, EA | 3 |
| Phillips, IR | 3 |
| Fujieda, M | 1 |
| Togashi, M | 1 |
| Saito, T | 1 |
| Kamataki, T | 2 |
| Menna, VJ | 1 |
| Varma, S | 1 |
| Podadera, P | 1 |
| Sipahi, AM | 1 |
| Arêas, JA | 1 |
| Lanfer-Marquez, UM | 1 |
| Busby, MG | 1 |
| Fischer, L | 1 |
| da Costa, KA | 1 |
| Thompson, D | 1 |
| Mar, MH | 1 |
| Zeisel, SH | 1 |
| Dolan, C | 1 |
| Shields, DC | 1 |
| Stanton, A | 1 |
| O'Brien, E | 1 |
| Lambert, DM | 2 |
| O'Brien, JK | 1 |
| Treacy, EP | 5 |
| Teresa, E | 1 |
| Lonardo, F | 1 |
| Fiumara, A | 1 |
| Lombardi, C | 1 |
| Russo, P | 1 |
| Zuppi, C | 1 |
| Scarano, G | 1 |
| Musumeci, S | 1 |
| Gianfrancesco, F | 1 |
| Fujita, H | 2 |
| Aoyama, T | 1 |
| Gunji, T | 1 |
| Ferrari, ND | 1 |
| Nield, LS | 1 |
| Arseculeratne, G | 1 |
| Wong, AK | 1 |
| Goudie, DR | 1 |
| Ferguson, J | 1 |
| Hsu, WY | 1 |
| Lo, WY | 1 |
| Lai, CC | 1 |
| Tsai, FJ | 1 |
| Tsai, CH | 1 |
| Tsai, Y | 1 |
| Lin, WD | 1 |
| Chao, MC | 1 |
| Werner, D | 1 |
| Johnson, DW | 1 |
| King, GS | 1 |
| Pettit, BR | 1 |
| Leonard, JV | 1 |
| Spellacy, E | 1 |
| Watts, RW | 1 |
| Goolamali, SK | 1 |
| Treacy, E | 2 |
| Johnson, D | 1 |
| Pitt, JJ | 1 |
| Danks, DM | 2 |
| Ruocco, V | 1 |
| Florio, M | 1 |
| Hadidi, HF | 1 |
| Cholerton, S | 1 |
| Atkinson, S | 1 |
| Irshaid, YM | 1 |
| Rawashdeh, NM | 1 |
| Idle, JR | 4 |
| Walker, V | 1 |
| Ayesh, R | 6 |
| Zhang, A | 1 |
| Chen, H | 1 |
| Aiello, F | 1 |
| Sela, BA | 1 |
| Trau, H | 1 |
| Spira, A | 1 |
| Zhang, AQ | 3 |
| Mitchell, S | 1 |
| Smith, R | 1 |
| Holmes, HC | 1 |
| Burns, SP | 1 |
| Michelakakis, H | 1 |
| Kordoni, V | 1 |
| Bain, MD | 1 |
| Chalmers, RA | 1 |
| Rafter, JE | 1 |
| Iles, RA | 1 |
| Fernández, MS | 1 |
| Gutiérrez, C | 1 |
| Vila, JJ | 1 |
| López, A | 1 |
| Ibáñez, V | 1 |
| Sangüesa, C | 1 |
| Lluna, J | 1 |
| Barrios, JE | 1 |
| Maschke, S | 1 |
| Wahl, A | 1 |
| Azaroual, N | 1 |
| Boulet, O | 1 |
| Crunelle, V | 1 |
| Imbenotte, M | 1 |
| Foulard, M | 1 |
| Vermeersch, G | 1 |
| Lhermitte, M | 1 |
| Bi, YA | 1 |
| Lin, J | 2 |
| Youil, R | 2 |
| Knight, M | 3 |
| Forrest, S | 1 |
| McConnell, HW | 1 |
| Brewster, M | 1 |
| Dolphin, CT | 2 |
| Janmohamed, A | 1 |
| Riley, JH | 1 |
| Thithapandha, A | 1 |
| Akerman, BR | 3 |
| Chow, LM | 2 |
| Bibeau, C | 2 |
| Bruce, AG | 1 |
| Forrest, SM | 2 |
| Yamaguchi, S | 1 |
| Kugel, H | 1 |
| Heindel, W | 1 |
| Roth, B | 1 |
| Ernst, S | 1 |
| Lackner, K | 1 |
| Lemass, H | 1 |
| Greenberg, C | 1 |
| Zschocke, J | 1 |
| Kohlmueller, D | 1 |
| Quak, E | 1 |
| Meissner, T | 1 |
| Hoffmann, GF | 1 |
| Mayatepek, E | 1 |
| Choinière, L | 1 |
| Kroemer, H | 1 |
| Eichelbaum, M | 1 |
| Pauszek, ME | 1 |
| Leopold, DA | 1 |
| Mozell, MM | 1 |
| Youngentob, SL | 1 |
| Wright, HN | 1 |
| al-Waiz, M | 3 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Phase II Study to Evaluate Oral Chlorophyllin in Hemorrhagic Cystitis Secondary to Radiation Therapy for Pelvic Malignancies[NCT05348239] | Phase 2 | 24 participants (Anticipated) | Interventional | 2022-03-26 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 reviews available for trimethylamine and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Archaea, specific genetic traits, and development of improved bacterial live biotherapeutic products: another face of next-generation probiotics.
Topics: Animals; Archaea; Biological Therapy; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Hu | 2020 |
Treatments of trimethylaminuria: where we are and where we might be heading.
Topics: Animals; Humans; Metabolism, Inborn Errors; Methylamines; Oxygenases | 2020 |
The complex metabolism of trimethylamine in humans: endogenous and exogenous sources.
Topics: Air Pollutants; Animals; Atherosclerosis; Diet; Humans; Metabolism, Inborn Errors; Methylamines; Neo | 2016 |
Biochemical and clinical aspects of the human flavin-containing monooxygenase form 3 (FMO3) related to trimethylaminuria.
Topics: Animals; Clinical Trials as Topic; Diet; Genotype; Humans; Hypertension; Liver; Metabolic Diseases; | 2003 |
Trimethylaminuria and a human FMO3 mutation database.
Topics: Alleles; Animals; Databases, Genetic; Genetic Variation; Humans; Metabolism, Inborn Errors; Methylam | 2003 |
Trimethylaminuria in a girl with Prader-Willi syndrome and del(15)(q11q13).
Topics: Animals; Child; Choline; Chromosome Deletion; Chromosomes, Human, Pair 15; Diet; Female; Fishes; Hum | 1993 |
The fish-odor syndrome.
Topics: Diet; Halitosis; Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Sweat; Syndrome | 1996 |
[Trimethylaminuria].
Topics: Diagnosis, Differential; Humans; Metabolism, Inborn Errors; Methylamines; Mutation; Oxygenases; Prog | 1998 |
2 trials available for trimethylamine and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Effects of the dietary supplements, activated charcoal and copper chlorophyllin, on urinary excretion of trimethylamine in Japanese trimethylaminuria patients.
Topics: Adult; Charcoal; Chlorophyllides; Diet; Dietary Supplements; Drug Therapy, Combination; Female; Huma | 2004 |
The fish odour syndrome: biochemical, familial, and clinical aspects.
Topics: Adolescent; Adult; Animals; Female; Fishes; Humans; Infant; Male; Mental Disorders; Metabolism, Inbo | 1993 |
66 other studies available for trimethylamine and Metabolism, Inborn Errors
| Article | Year |
|---|---|
Adaptive Modelling of Mutated FMO3 Enzyme Could Unveil Unexplored Scenarios Linking Variant Haplotypes to TMAU Phenotypes.
Topics: Adult; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Models, Molecular; Mutation; N | 2021 |
A family study of compound variants of flavin-containing monooxygenase 3 (FMO3) in Japanese subjects found by urinary phenotyping for trimethylaminuria.
Topics: Child; East Asian People; Female; Humans; Infant; Metabolism, Inborn Errors; Oxygenases | 2023 |
Novel variants in outer protein surface of flavin-containing monooxygenase 3 found in an Argentinian case with impaired capacity for trimethylamine N-oxygenation.
Topics: Argentina; Cell Membrane; Child; Female; Humans; Metabolism, Inborn Errors; Methylamines; Oxygen; Ox | 2020 |
Antiretroviral treatment leading to secondary trimethylaminuria: Genetic associations and successful management with riboflavin.
Topics: Adult; Anti-Retroviral Agents; HIV Infections; Humans; Magnetic Resonance Imaging; Male; Metabolism, | 2021 |
Quality consideration for the validation of urine TMA and TMAO measurement by nuclear magnetic resonance spectroscopy in Fish Odor Syndrome.
Topics: Calibration; Female; Humans; Magnetic Resonance Spectroscopy; Metabolism, Inborn Errors; Methylamine | 2021 |
Inactivation mechanism of N61S mutant of human FMO3 towards trimethylamine.
Topics: Computer Simulation; Humans; In Vitro Techniques; Metabolism, Inborn Errors; Methylamines; Mutation; | 2017 |
Primary trimethylaminuria (fish odor syndrome) and hypothyroidism in an adolescent.
Topics: Adolescent; Humans; Hypothyroidism; Male; Metabolism, Inborn Errors; Methylamines; Metronidazole; Mu | 2017 |
Something fishy going on.
Topics: Adult; Dietary Supplements; Humans; Male; Metabolism, Inborn Errors; Methylamines; Odorants | 2018 |
Index of suspicion.
Topics: Adolescent; Anticoagulants; Diagnosis, Differential; Diet Therapy; Embolism, Paradoxical; Female; Ga | 2013 |
Fish odor syndrome (trimethylaminuria) supporting the possible FMO3 down expression in childhood: a case report.
Topics: Biomarkers; Child; Down-Regulation; Female; Genetic Markers; Humans; Metabolism, Inborn Errors; Meth | 2014 |
Fish Malodour syndrome in a child.
Topics: Child, Preschool; Diagnosis, Differential; Diet Therapy; Female; Humans; Hygiene; Metabolism, Inborn | 2015 |
Genetic analysis of impaired trimethylamine metabolism using whole exome sequencing.
Topics: Adolescent; Adult; Aged; Choline; DNA; Female; Genetic Testing; Genotype; Humans; INDEL Mutation; Ma | 2017 |
[Dietetic approach to trimethylaminuria].
Topics: Adult; Female; Humans; Metabolism, Inborn Errors; Methylamines | 2010 |
Perioperative recommendations in a child with Fish Odor syndrome.
Topics: Adenoidectomy; Anesthesia, Intravenous; Anesthetics, Intravenous; Child; Humans; Male; Metabolism, I | 2009 |
What have we here? A man or a fish?
Topics: Humans; Liver; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Mutation; Odorants; Oxyge | 2010 |
Developmental variations in metabolic capacity of flavin-containing mono-oxygenase 3 in childhood.
Topics: Age Factors; Antioxidants; Child Development; Female; Gene Expression; Humans; Infant; Infant, Newbo | 2011 |
Fish odour syndrome.
Topics: Aged; Female; Fluorobenzenes; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholester | 2011 |
Variants in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Topics: Adult; Alleles; Child, Preschool; DNA Mutational Analysis; Escherichia coli; Female; Gene Frequency; | 2012 |
A nonsense mutation in the FMO3 gene underlies fishy off-flavor in cow's milk.
Topics: Amino Acid Substitution; Animals; Arginine; Cattle; Codon, Nonsense; Exons; Female; Genetic Carrier | 2002 |
Fish odour syndrome with features of both primary and secondary trimethylaminuria.
Topics: Biomarkers; Female; Humans; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants | 2003 |
Trimethylaminuria (fish odor syndrome) related to the choline concentration of infant formula.
Topics: Choline; Halitosis; Humans; Infant; Infant Food; Male; Metabolism, Inborn Errors; Methylamines; Odor | 2003 |
Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.
Topics: Amino Acid Sequence; Base Sequence; DNA Primers; Humans; Metabolism, Inborn Errors; Methylamines; Mo | 2003 |
Question from the clinician: malodorous breath, hair, and body.
Topics: Child; Hair; Halitosis; Humans; Metabolism, Inborn Errors; Methylamines; Odorants | 2004 |
Diagnosis of suspected trimethylaminuria by NMR spectroscopy.
Topics: Adult; Amines; Animals; Choline; Diet; Dogfish; Humans; Magnetic Resonance Spectroscopy; Male; Metab | 2005 |
Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria.
Topics: Betaine; Choline; Dietary Supplements; Dietetics; Dose-Response Relationship, Drug; Food Analysis; H | 2004 |
Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians.
Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Genetic Predispositio | 2005 |
A spectrum of molecular variation in a cohort of Italian families with trimethylaminuria: identification of three novel mutations of the FM03 gene.
Topics: Cohort Studies; DNA Mutational Analysis; Female; Frameshift Mutation; Gene Deletion; Haplotypes; Het | 2006 |
Three novel single nucleotide polymorphisms of the FMO3 gene in a Japanese population.
Topics: Alleles; Amino Acid Substitution; Asian People; Base Sequence; Exons; Female; Haplotypes; Humans; Ja | 2006 |
Stop codon mutations in the flavin-containing monooxygenase 3 (FMO3) gene responsible for trimethylaminuria in a Japanese population.
Topics: Adolescent; Adult; Child; Child, Preschool; Codon, Nonsense; Female; Humans; Infant; Japan; Male; Me | 2007 |
Smelling like dead fish: a case of trimethylaminuria in an adolescent.
Topics: Adolescent; Anti-Infective Agents; Biomarkers; Carnitine; Choline; Creatinine; Humans; Male; Metabol | 2006 |
Trimethylaminuria (fish-odor syndrome): a case report.
Topics: Adult; Antioxidants; Consanguinity; Humans; Male; Metabolism, Inborn Errors; Methylamines; Mutation; | 2007 |
Transient trimethylaminuria related to menstruation.
Topics: Adult; Female; Heterozygote; Homozygote; Humans; Menstruation; Metabolism, Inborn Errors; Methylamin | 2007 |
Rapid screening assay of trimethylaminuria in urine with matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Topics: Child, Preschool; Female; Humans; Infant; Metabolism, Inborn Errors; Methylamines; Reproducibility o | 2007 |
[Trimethylaminuria (fish-odour syndrome)--hints for a new therapeutic option with desmopressin].
Topics: Antidiuretic Agents; Child, Preschool; Deamino Arginine Vasopressin; Fish Products; Humans; Male; Me | 2007 |
A flow injection electrospray ionization tandem mass spectrometric method for the simultaneous measurement of trimethylamine and trimethylamine N-oxide in urine.
Topics: Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Spectrometry, Mass, Electrospray Ionizati | 2008 |
The analysis of trimethylamine in body fluids by a direct medium resolution mass spectrometric method.
Topics: Female; Humans; Mass Spectrometry; Metabolism, Inborn Errors; Methylamines | 1984 |
Trimethylaminuria.
Topics: Animals; Child; Choline; Creatinine; Diet; Female; Fishes; Humans; Meat; Metabolism, Inborn Errors; | 1980 |
Trimethylaminuria, fish odour syndrome: a new method of detection and response to treatment with metronidazole.
Topics: Adult; Child; Female; Humans; Male; Mass Spectrometry; Metabolism, Inborn Errors; Methylamines; Metr | 1995 |
Fish-odor syndrome: an olfactory diagnosis.
Topics: Diet; Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Sweat; Syndrome | 1995 |
The N-oxidation of trimethylamine in a Jordanian population.
Topics: Adult; Ethnicity; Female; Humans; Jordan; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged | 1995 |
The fish odour syndrome.
Topics: Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidation-Reduction; Syndrome | 1993 |
[Trimethylaminuria: fish-odor syndrome].
Topics: Adult; Female; Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Respiration; Sweat | 1993 |
Fish odour syndrome: verification of carrier detection test.
Topics: Adult; Female; Genetic Carrier Screening; Humans; Male; Metabolism, Inborn Errors; Methylamines; Odo | 1995 |
Discontinuous distribution of N-oxidation of dietary-derived trimethylamine in a British population.
Topics: Adult; Diet; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odorants; O | 1996 |
Choline and L-carnitine as precursors of trimethylamine.
Topics: Animals; Carnitine; Child, Preschool; Choline; Female; Fishes; Humans; Magnetic Resonance Spectrosco | 1997 |
Congenital intrahepatic portocaval shunt associated with trimethylaminuria.
Topics: Arteriovenous Malformations; Child; Child, Preschool; Female; Follow-Up Studies; Humans; Infant; Liv | 1997 |
1H-NMR analysis of trimethylamine in urine for the diagnosis of fish-odour syndrome.
Topics: Amine Oxidase (Copper-Containing); Female; Humans; Liver; Magnetic Resonance Spectroscopy; Male; Met | 1997 |
Human flavin-containing monooxygenase form 3: cDNA expression of the enzymes containing amino acid substitutions observed in individuals with trimethylaminuria.
Topics: DNA, Complementary; Humans; Metabolism, Inborn Errors; Methylamines; Mutation; Odorants; Oxygenases; | 1997 |
Trimethylaminuria associated with seizures and behavioural disturbance: a case report.
Topics: Adolescent; Child; Child Behavior Disorders; Choline; Diagnosis, Differential; Epilepsy, Complex Par | 1997 |
Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome.
Topics: Amino Acid Sequence; Animals; Base Sequence; Humans; Metabolism, Inborn Errors; Methylamines; Molecu | 1997 |
Structural organization of the human flavin-containing monooxygenase 3 gene (FMO3), the favored candidate for fish-odor syndrome, determined directly from genomic DNA.
Topics: Exons; Flavin-Adenine Dinucleotide; Humans; Introns; Metabolism, Inborn Errors; Methylamines; Molecu | 1997 |
A pharmacogenetic study of trimethylaminuria in Orientals.
Topics: Adult; Asian People; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Middle Aged; Odo | 1997 |
Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.
Topics: Adolescent; Adult; Child; Child, Preschool; Cloning, Molecular; DNA, Complementary; Haplotypes; Huma | 1998 |
Proton MR spectroscopy in infants with cerebral energy deficiency due to hypoxia and metabolic disorders.
Topics: Aspartic Acid; Basal Ganglia; Brain; Brain Diseases, Metabolic; Child, Preschool; Follow-Up Studies; | 1998 |
Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.
Topics: Adult; Alleles; Amino Acid Substitution; Child; Child, Preschool; Cohort Studies; DNA; DNA Mutationa | 1999 |
Mild trimethylaminuria caused by common variants in FMO3 gene.
Topics: Adult; Child; Genes, Recessive; Genetic Variation; Humans; Metabolism, Inborn Errors; Methylamines; | 1999 |
Measurement of trimethylamine and trimethylamine N-oxide independently in urine by fast atom bombardment mass spectrometry.
Topics: Case-Control Studies; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Reference Value | 1999 |
Trimethylaminuria: the fish malodor syndrome.
Topics: Humans; Metabolism, Inborn Errors; Methylamines; Oxidation-Reduction; Polymorphism, Genetic | 2001 |
A novel deletion in the flavin-containing monooxygenase gene (FMO3) in a Greek patient with trimethylaminuria.
Topics: Adolescent; Base Sequence; Blotting, Southern; DNA Primers; Exons; Gene Deletion; Greece; Homozygote | 2001 |
Determination of trimethylamine and related aliphatic amines in human urine by head-space gas chromatography.
Topics: Amines; Chromatography, Gas; Humans; Metabolism, Inborn Errors; Methylamines; Odorants | 1992 |
Metabolism of verapamil in a family pedigree with deficient N-oxidation of trimethylamine.
Topics: Adult; Aged; Dealkylation; Female; Heterozygote; Humans; Male; Metabolism, Inborn Errors; Methylamin | 1991 |
Fishing for a diagnosis.
Topics: Adolescent; Choline; Humans; Male; Metabolism, Inborn Errors; Methylamines; Odorants | 1991 |
Fish-odor syndrome presenting as dysosmia.
Topics: Adult; Female; Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Smell | 1990 |
Trimethylaminuria: the detection of carriers using a trimethylamine load test.
Topics: Administration, Oral; Adult; Genetic Carrier Screening; Humans; Male; Metabolism, Inborn Errors; Met | 1989 |
Trimethylaminuria (fish-odour syndrome): an inborn error of oxidative metabolism.
Topics: Animals; Child; Female; Fishes; Humans; Metabolism, Inborn Errors; Methylamines; Odorants; Oxidation | 1987 |
Trimethylaminuria ('fish-odour syndrome'): a study of an affected family.
Topics: Adult; Female; Humans; Male; Metabolism, Inborn Errors; Methylamines; Syndrome | 1988 |