trimethylamine has been researched along with Kidney Failure, Chronic in 7 studies
Kidney Failure, Chronic: The end-stage of CHRONIC RENAL INSUFFICIENCY. It is characterized by the severe irreversible kidney damage (as measured by the level of PROTEINURIA) and the reduction in GLOMERULAR FILTRATION RATE to less than 15 ml per min (Kidney Foundation: Kidney Disease Outcome Quality Initiative, 2002). These patients generally require HEMODIALYSIS or KIDNEY TRANSPLANTATION.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The changes of intestinal bacteria in ESRD patients have contributed to the accumulation of gut-derived uremic toxins such as TMAO, indoxyl sulfate and indole-3-acetic acid." | 2.82 | [Gut-derived uremic toxin trimethylamine-N-oxide in cardiovascular disease under end-stage renal disease: an injury mechanism and therapeutic target]. ( Ren, Y; Wang, Z; Xue, J, 2022) |
| "L-Carnitine has important roles in intermediary metabolism and patients with end-stage renal disease who are undergoing hemodialysis may develop a secondary L-carnitine deficiency." | 2.72 | Oral L-carnitine: metabolite formation and hemodialysis. ( Bain, MA; Evans, AM; Faull, R; Milne, RW, 2006) |
| "Trimethylamine (TMA) is a volatile tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods containing TMA, or by the intake of food containing precursors to TMA such as trimethylamine-N-oxide (TMNO), choline and L-carnitine." | 2.43 | Trimethylamine: metabolic, pharmacokinetic and safety aspects. ( Bain, MA; Evans, AM; Fornasini, G, 2005) |
| "Trimethylamine (TMA) is a short-chain tertiary aliphatic amine that is derived from the diet either directly from the consumption of foods high in TMA or by the intake of food high in precursors to TMA, such as trimethylamine-N-oxide (TMNO), choline and L-carnitine." | 1.33 | Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis. ( Bain, MA; Evans, AM; Faull, R; Fornasini, G; Milne, RW, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (14.29) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (42.86) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 2 (28.57) | 2.80 |
| Authors | Studies |
|---|---|
| Chang, D | 1 |
| Xu, X | 1 |
| Yang, Z | 1 |
| Ma, T | 1 |
| Nie, J | 1 |
| Dong, J | 1 |
| Ren, Y | 1 |
| Wang, Z | 1 |
| Xue, J | 1 |
| Grabowska-Polanowska, B | 1 |
| Miarka, P | 1 |
| Skowron, M | 1 |
| Chmiel, G | 1 |
| Pietrzycka, A | 1 |
| Śliwka, I | 1 |
| Bain, MA | 3 |
| Fornasini, G | 2 |
| Evans, AM | 3 |
| Faull, R | 2 |
| Milne, RW | 2 |
| Ihle, BU | 1 |
| Cox, RW | 1 |
| Dunn, SR | 1 |
| Simenhoff, ML | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Impact of Diet and Gut Microbiota on Trimethylamine-N-oxide Production and Fate in Humans[NCT02558673] | 40 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for trimethylamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
[Gut-derived uremic toxin trimethylamine-N-oxide in cardiovascular disease under end-stage renal disease: an injury mechanism and therapeutic target].
Topics: Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Methylamines; Oxides; Uremic Toxins | 2022 |
Trimethylamine: metabolic, pharmacokinetic and safety aspects.
Topics: Animals; Humans; Kidney Failure, Chronic; Methylamines | 2005 |
1 trial available for trimethylamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Oral L-carnitine: metabolite formation and hemodialysis.
Topics: Administration, Oral; Adult; Aged; Carnitine; Humans; Kidney Failure, Chronic; Male; Methylamines; M | 2006 |
4 other studies available for trimethylamine and Kidney Failure, Chronic
| Article | Year |
|---|---|
Trimethylamine-N-oxide (TMAO) and clinical outcomes in patients with end-stage kidney disease receiving peritoneal dialysis.
Topics: Biomarkers; Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Oxides; Peritoneal Dialysis; P | 2022 |
Breath analysis as promising indicator of hemodialysis efficiency.
Topics: Biomarkers; Breath Tests; Butadienes; Creatinine; Female; Gas Chromatography-Mass Spectrometry; Hemi | 2019 |
Accumulation of trimethylamine and trimethylamine-N-oxide in end-stage renal disease patients undergoing haemodialysis.
Topics: Adult; Biomarkers; Case-Control Studies; Disease Progression; Female; Follow-Up Studies; Humans; Kid | 2006 |
Determination of body burden of uremic toxins.
Topics: Adolescent; Adult; Child; Dimethylamines; Extracellular Space; Female; Humans; Intracellular Fluid; | 1984 |