trimethylamine has been researched along with Hepatitis in 2 studies
Hepatitis: INFLAMMATION of the LIVER.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 2 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Helsley, RN | 1 |
| Miyata, T | 1 |
| Kadam, A | 1 |
| Varadharajan, V | 1 |
| Sangwan, N | 1 |
| Huang, EC | 1 |
| Banerjee, R | 1 |
| Brown, AL | 1 |
| Fung, KK | 1 |
| Massey, WJ | 1 |
| Neumann, C | 1 |
| Orabi, D | 1 |
| Osborn, LJ | 1 |
| Schugar, RC | 1 |
| McMullen, MR | 1 |
| Bellar, A | 1 |
| Poulsen, KL | 1 |
| Kim, A | 1 |
| Pathak, V | 1 |
| Mrdjen, M | 1 |
| Anderson, JT | 1 |
| Willard, B | 1 |
| McClain, CJ | 1 |
| Mitchell, M | 1 |
| McCullough, AJ | 1 |
| Radaeva, S | 1 |
| Barton, B | 1 |
| Szabo, G | 1 |
| Dasarathy, S | 1 |
| Garcia-Garcia, JC | 1 |
| Rotroff, DM | 1 |
| Allende, DS | 1 |
| Wang, Z | 1 |
| Hazen, SL | 1 |
| Nagy, LE | 1 |
| Brown, JM | 1 |
| Lim, T | 1 |
| Ryu, J | 1 |
| Lee, K | 1 |
| Park, SY | 1 |
| Hwang, KT | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind Randomized Controlled Trial of Anakinra, Pentoxifylline, and Zinc Compared to Methylprednisolone in Severe Acute Alcoholic Hepatitis[NCT01809132] | Phase 2/Phase 3 | 104 participants (Actual) | Interventional | 2013-09-30 | Completed | ||
| Comparison of ALD, NASH, and Healthy Control Patients[NCT03224949] | 500 participants (Anticipated) | Observational | 2017-06-19 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Death at 180 days (NCT01809132)
Timeframe: Time to event up to 6 months
| Intervention | Participants (Count of Participants) |
|---|---|
| Anakinra & Pentoxifylline & Zinc Sulfate | 17 |
| Methylprednisolone | 22 |
| Observational | 0 |
"Model of End Stage Liver Disease Score calculated from serum bilirubin, serum creatinine, and the international normalized ratio for prothrombin time (INR). MELD score ranges from 6-40. A higher score indicates a lesser outcome.~The Model for End Stage Liver Disease scoring system is based on the INR, total serum bilirubin and serum creatinine. The measure reflects 90 day prognosis of alcohol associated liver disease from the time of measurement and therefore can only be assessed on subjects who are alive at the specified time point since lab values from that time point are required for the measure." (NCT01809132)
Timeframe: 180 Days
| Intervention | score on a scale (Mean) |
|---|---|
| Anakinra & Pentoxifylline & Zinc Sulfate | 15.81 |
| Methylprednisolone | 11.85 |
"Model of End Stage Liver Disease Score calculated from serum bilirubin, serum creatinine, and the international normalized ratio for prothrombin time (INR). MELD score ranges from 6-40. A higher score indicates a lesser outcome.~The Model for End Stage Liver Disease scoring system is based on the INR, total serum bilirubin and serum creatinine. The measure reflects 90 day prognosis of alcohol associated liver disease from the time of measurement and therefore can only be assessed on subjects who are alive at the specified time point since lab values from that time point are required for the measure." (NCT01809132)
Timeframe: 28 days
| Intervention | score on a scale (Mean) |
|---|---|
| Anakinra & Pentoxifylline & Zinc Sulfate | 22.57 |
| Methylprednisolone | 20.95 |
"Model of End Stage Liver Disease Score calculated from serum bilirubin, serum creatinine, and the international normalized ratio for prothrombin time (INR). MELD score ranges from 6-40. A higher score indicates a lesser outcome.~The Model for End Stage Liver Disease scoring system is based on the INR, total serum bilirubin and serum creatinine. The measure reflects 90 day prognosis of alcohol associated liver disease from the time of measurement and therefore can only be assessed on subjects who are alive at the specified time point since lab values from that time point are required for the measure." (NCT01809132)
Timeframe: 90 Days
| Intervention | score on a scale (Mean) |
|---|---|
| Anakinra & Pentoxifylline & Zinc Sulfate | 15.50 |
| Methylprednisolone | 16.38 |
2 other studies available for trimethylamine and Hepatitis
| Article | Year |
|---|---|
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury, Chronic; Ethanol; Female; Gastrointestina | 2022 |
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury, Chronic; Ethanol; Female; Gastrointestina | 2022 |
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury, Chronic; Ethanol; Female; Gastrointestina | 2022 |
Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice.
Topics: Animals; Bacteria; Chemical and Drug Induced Liver Injury, Chronic; Ethanol; Female; Gastrointestina | 2022 |
Protective Effects of Black Raspberry (
Topics: Animals; Anthocyanins; Cecum; Choline; Cyclooxygenase 2; Diet, High-Fat; Dietary Supplements; Eating | 2020 |