Page last updated: 2024-10-20

trimethylamine and Fatty Liver, Nonalcoholic

trimethylamine has been researched along with Fatty Liver, Nonalcoholic in 7 studies

Research Excerpts

ExcerptRelevanceReference
"Evidence shows that trimethylamine (TMA)/trimethylamine-N-oxide (TMAO) is closely related to non-alcoholic fatty liver disease (NAFLD)."8.12Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine. ( Cao, P; Chen, Q; Deng, W; Gong, Z; Guo, J; Li, X; Pei, M; Shi, C; Wang, L; Wang, Y; Zhang, L, 2022)
"Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disorder with complicated pathophysiology."5.72Possible correlation between high circulatory levels of trimethylamine-N-oxide and 2177G>C polymorphisms of hepatic flavin containing monooxygenase 3 in Kurdish Population with non-alcoholic fatty liver disease. ( Abdi, M; Ghaderi, D; Moloudi, MR; Moradzad, M; Rahmani, K; Sheikh Esmaeili, F; Vahabzadeh, Z, 2022)
"Evidence shows that trimethylamine (TMA)/trimethylamine-N-oxide (TMAO) is closely related to non-alcoholic fatty liver disease (NAFLD)."4.12Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine. ( Cao, P; Chen, Q; Deng, W; Gong, Z; Guo, J; Li, X; Pei, M; Shi, C; Wang, L; Wang, Y; Zhang, L, 2022)
"Choline is a water-soluble nutrient essential for human life."2.66The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases. ( Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A, 2020)
"The spectrum of NAFLD includes non-alcoholic fatty liver, non-alcoholic steatohepatitis, liver cirrhosis, and even hepatocellular carcinoma."2.61Microbial metabolites in non-alcoholic fatty liver disease. ( Fan, JG; Zhou, D, 2019)
"Non-alcoholic fatty liver disease (NAFLD) is a multifactorial disorder with complicated pathophysiology."1.72Possible correlation between high circulatory levels of trimethylamine-N-oxide and 2177G>C polymorphisms of hepatic flavin containing monooxygenase 3 in Kurdish Population with non-alcoholic fatty liver disease. ( Abdi, M; Ghaderi, D; Moloudi, MR; Moradzad, M; Rahmani, K; Sheikh Esmaeili, F; Vahabzadeh, Z, 2022)
"Liver fibrosis is one main histological characteristic of nonalcoholic steatohepatitis (NASH), a disease paralleling a worldwide surge in metabolic syndromes with no approved therapies."1.72Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis. ( Ding, BS; Mo, C; Xiao, C; Zhang, J; Zhou, D, 2022)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (28.57)24.3611
2020's5 (71.43)2.80

Authors

AuthorsStudies
Shi, C1
Pei, M1
Wang, Y1
Chen, Q1
Cao, P1
Zhang, L1
Guo, J1
Deng, W1
Wang, L1
Li, X1
Gong, Z1
Moradzad, M1
Abdi, M1
Sheikh Esmaeili, F1
Ghaderi, D1
Rahmani, K1
Moloudi, MR1
Vahabzadeh, Z1
Zhou, D2
Zhang, J1
Xiao, C1
Mo, C1
Ding, BS1
Arias, N1
Arboleya, S1
Allison, J1
Kaliszewska, A1
Higarza, SG1
Gueimonde, M1
Arias, JL1
Flores-Guerrero, JL1
Post, A1
van Dijk, PR1
Connelly, MA1
Garcia, E1
Navis, G1
Bakker, SJL1
Dullaart, RPF1
Chu, H1
Duan, Y1
Yang, L1
Schnabl, B1
Fan, JG1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Alterations of Gut Microbiota and Metabolites in Asian Patients With Alcohol-associated Liver Disease[NCT05448144]200 participants (Anticipated)Observational2022-06-01Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for trimethylamine and Fatty Liver, Nonalcoholic

ArticleYear
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
    Nutrients, 2020, Aug-05, Volume: 12, Issue:8

    Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestina

2020
Small metabolites, possible big changes: a microbiota-centered view of non-alcoholic fatty liver disease.
    Gut, 2019, Volume: 68, Issue:2

    Topics: Bile Acids and Salts; Disease Progression; Dysbiosis; Ethanol; Fatty Acids, Volatile; Gastrointestin

2019
Microbial metabolites in non-alcoholic fatty liver disease.
    World journal of gastroenterology, 2019, May-07, Volume: 25, Issue:17

    Topics: Bile Acids and Salts; Disease Progression; Ethanol; Fatty Acids, Volatile; Fermentation; Gastrointes

2019

Other Studies

4 other studies available for trimethylamine and Fatty Liver, Nonalcoholic

ArticleYear
Changes of flavin-containing monooxygenases and trimethylamine-N-oxide may be involved in the promotion of non-alcoholic fatty liver disease by intestinal microbiota metabolite trimethylamine.
    Biochemical and biophysical research communications, 2022, 02-26, Volume: 594

    Topics: Animals; Cell Line; Endoplasmic Reticulum Chaperone BiP; Gastrointestinal Microbiome; Gene Silencing

2022
Possible correlation between high circulatory levels of trimethylamine-N-oxide and 2177G>C polymorphisms of hepatic flavin containing monooxygenase 3 in Kurdish Population with non-alcoholic fatty liver disease.
    Molecular biology reports, 2022, Volume: 49, Issue:7

    Topics: Case-Control Studies; Chromatography, Liquid; Flavins; Humans; Methylamines; Mixed Function Oxygenas

2022
Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis.
    Frontiers in immunology, 2022, Volume: 13

    Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Liver Cirrhosis; Methylamines; Mice; N

2022
Circulating trimethylamine-N-oxide is associated with all-cause mortality in subjects with nonalcoholic fatty liver disease.
    Liver international : official journal of the International Association for the Study of the Liver, 2021, Volume: 41, Issue:10

    Topics: Biomarkers; Cohort Studies; Humans; Methylamines; Non-alcoholic Fatty Liver Disease; Oxides; Prospec

2021