trimethylamine has been researched along with Disease Models, Animal in 15 studies
Disease Models, Animal: Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis." | 8.02 | Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021) |
| "Trimethylamine-N-oxide (TMAO), a derivative from the gut microbiota metabolite trimethylamine (TMA), has been identified to be an independent risk factor for promoting atherosclerosis." | 4.02 | Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome. ( Du, Y; Hong, B; Jiang, J; Jiang, Z; Li, X; Su, C; Wang, L; Yang, M; Yang, Y; Zhang, J; Zhang, X; Zhang, Y, 2021) |
| " Furthermore, unlike chronic dietary choline, TML supplementation in mice failed to elevate plasma TMAO or heighten thrombosis potential in vivo." | 3.88 | Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk. ( Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y, 2018) |
| "The functional significance of gap-junction (GJ) channels in seizure susceptibility and induction and maintenance of seizures in the developing rat brain was investigated on the 4-aminopyridine (4-AP) in vivo epilepsy model." | 3.73 | The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats. ( Gajda, Z; Gyengési, E; Hermesz, E; Szente, M; Szupera, Z, 2006) |
| "The possible role of gap junctions in the manifestation and control of the duration of seizures was tested on the 4-aminopyridine-induced epilepsy model in rats in vivo, by using electrophysiologic, pharmacologic, and molecular biologic techniques." | 3.72 | Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo. ( Ali, KS; Gajda, Z; Gyengési, E; Hermesz, E; Szente, M, 2003) |
| "Liver fibrosis is one main histological characteristic of nonalcoholic steatohepatitis (NASH), a disease paralleling a worldwide surge in metabolic syndromes with no approved therapies." | 1.72 | Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis. ( Ding, BS; Mo, C; Xiao, C; Zhang, J; Zhou, D, 2022) |
| "Trimethylamine was used as a probe substrate to assess FMO activity." | 1.51 | Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease. ( Leblond, FA; Nolin, TD; Pichette, V; Prokopienko, AJ; Schrum, DP; Stubbs, JR; West, RE, 2019) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (6.67) | 18.2507 |
| 2000's | 6 (40.00) | 29.6817 |
| 2010's | 5 (33.33) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, D | 1 |
| Zhang, J | 2 |
| Xiao, C | 1 |
| Mo, C | 1 |
| Ding, BS | 1 |
| Prokopienko, AJ | 1 |
| West, RE | 1 |
| Schrum, DP | 1 |
| Stubbs, JR | 1 |
| Leblond, FA | 1 |
| Pichette, V | 1 |
| Nolin, TD | 1 |
| Liu, J | 1 |
| Zhang, T | 1 |
| Wang, Y | 2 |
| Si, C | 1 |
| Wang, X | 1 |
| Wang, RT | 1 |
| Lv, Z | 1 |
| Li, X | 1 |
| Su, C | 1 |
| Jiang, Z | 2 |
| Yang, Y | 1 |
| Zhang, Y | 1 |
| Yang, M | 1 |
| Zhang, X | 1 |
| Du, Y | 1 |
| Wang, L | 1 |
| Jiang, J | 1 |
| Hong, B | 1 |
| Li, XS | 1 |
| Wang, Z | 2 |
| Cajka, T | 1 |
| Buffa, JA | 1 |
| Nemet, I | 1 |
| Hurd, AG | 1 |
| Gu, X | 1 |
| Skye, SM | 1 |
| Roberts, AB | 1 |
| Wu, Y | 1 |
| Li, L | 1 |
| Shahen, CJ | 1 |
| Wagner, MA | 1 |
| Hartiala, JA | 1 |
| Kerby, RL | 1 |
| Romano, KA | 1 |
| Han, Y | 1 |
| Obeid, S | 1 |
| Lüscher, TF | 1 |
| Allayee, H | 2 |
| Rey, FE | 1 |
| DiDonato, JA | 1 |
| Fiehn, O | 1 |
| Tang, WHW | 1 |
| Hazen, SL | 2 |
| Shih, DM | 1 |
| Zhu, W | 1 |
| Schugar, RC | 1 |
| Meng, Y | 1 |
| Jia, X | 1 |
| Miikeda, A | 1 |
| Zieger, M | 1 |
| Lee, R | 1 |
| Graham, M | 1 |
| Cantor, RM | 1 |
| Mueller, C | 1 |
| Brown, JM | 1 |
| Lusis, AJ | 1 |
| Chen, Y | 1 |
| Weng, Z | 1 |
| Liu, Q | 1 |
| Shao, W | 1 |
| Guo, W | 1 |
| Chen, C | 1 |
| Jiao, L | 1 |
| Wang, Q | 1 |
| Lu, Q | 1 |
| Sun, H | 1 |
| Gu, A | 1 |
| Hu, H | 1 |
| Yang, W | 1 |
| Zhang, S | 1 |
| Zhu, J | 1 |
| Jiang, H | 1 |
| Jia, D | 1 |
| Ou, T | 1 |
| Qi, Z | 1 |
| Zou, Y | 1 |
| Qian, J | 1 |
| Sun, A | 1 |
| Ge, J | 1 |
| Johnston, JB | 1 |
| Silva, C | 1 |
| Hiebert, T | 1 |
| Buist, R | 1 |
| Dawood, MR | 1 |
| Peeling, J | 1 |
| Power, C | 1 |
| Gajda, Z | 2 |
| Gyengési, E | 2 |
| Hermesz, E | 2 |
| Ali, KS | 1 |
| Szente, M | 2 |
| Utzinger, J | 1 |
| Xiao, SH | 1 |
| Xue, J | 1 |
| Nicholson, JK | 1 |
| Tanner, M | 1 |
| Singer, BH | 1 |
| Holmes, E | 1 |
| Proulx, E | 1 |
| Leshchenko, Y | 1 |
| Kokarovtseva, L | 1 |
| Khokhotva, V | 1 |
| El-Beheiry, M | 1 |
| Snead, OC | 1 |
| Perez Velazquez, JL | 1 |
| Szupera, Z | 1 |
| Wang, YJ | 1 |
| Ho, YS | 1 |
| Lo, MJ | 1 |
| Lin, JK | 1 |
| Köhling, R | 1 |
| Gladwell, SJ | 1 |
| Bracci, E | 1 |
| Vreugdenhil, M | 1 |
| Jefferys, JG | 1 |
15 other studies available for trimethylamine and Disease Models, Animal
| Article | Year |
|---|---|
Trimethylamine-N-oxide (TMAO) mediates the crosstalk between the gut microbiota and hepatic vascular niche to alleviate liver fibrosis in nonalcoholic steatohepatitis.
Topics: Animals; Disease Models, Animal; Gastrointestinal Microbiome; Liver Cirrhosis; Methylamines; Mice; N | 2022 |
Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease.
Topics: Activation, Metabolic; Animals; Blood Urea Nitrogen; Creatinine; Cytochrome P-450 CYP1A2; Disease Mo | 2019 |
Baicalin ameliorates neuropathology in repeated cerebral ischemia-reperfusion injury model mice by remodeling the gut microbiota.
Topics: Animals; Brain; Clusterin; Cytokines; Disease Models, Animal; Flavonoids; Gastrointestinal Microbiom | 2020 |
Berberine attenuates choline-induced atherosclerosis by inhibiting trimethylamine and trimethylamine-N-oxide production via manipulating the gut microbiome.
Topics: Animals; Atherosclerosis; Berberine; Choline; Diet; Disease Models, Animal; Disease Susceptibility; | 2021 |
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Mo | 2018 |
Genetic Deficiency of Flavin-Containing Monooxygenase 3 ( Fmo3) Protects Against Thrombosis but Has Only a Minor Effect on Plasma Lipid Levels-Brief Report.
Topics: Animals; Atherosclerosis; Choline; Disease Models, Animal; Lipid Metabolism; Methylamines; Mice; Mic | 2019 |
FMO3 and its metabolite TMAO contribute to the formation of gallstones.
Topics: Animals; Atherosclerosis; ATP Binding Cassette Transporter, Subfamily G, Member 5; ATP Binding Casse | 2019 |
Gut microbe-derived metabolite trimethylamine N-oxide accelerates fibroblast-myofibroblast differentiation and induces cardiac fibrosis.
Topics: Animals; Cell Differentiation; Collagen Type I; Disease Models, Animal; Fibroblasts; Fibrosis; Gastr | 2019 |
Neurovirulence depends on virus input titer in brain in feline immunodeficiency virus infection: evidence for activation of innate immunity and neuronal injury.
Topics: Animals; Animals, Newborn; Aspartic Acid; Brain; Cats; CD4-Positive T-Lymphocytes; Cells, Cultured; | 2002 |
Involvement of gap junctions in the manifestation and control of the duration of seizures in rats in vivo.
Topics: 4-Aminopyridine; Animals; Carbenoxolone; Cerebral Cortex; Connexin 43; Connexins; Disease Models, An | 2003 |
System level metabolic effects of a Schistosoma japonicum infection in the Syrian hamster.
Topics: Animals; Carboxylic Acids; Citric Acid Cycle; Cresols; Cricetinae; Disease Models, Animal; Fatty Aci | 2006 |
Functional contribution of specific brain areas to absence seizures: role of thalamic gap-junctional coupling.
Topics: Animals; Animals, Newborn; Brain Mapping; Carbenoxolone; Disease Models, Animal; Electrodes; Electro | 2006 |
The functional significance of gap junction channels in the epileptogenicity and seizure susceptibility of juvenile rats.
Topics: 4-Aminopyridine; Animals; Animals, Newborn; Carbenoxolone; Connexins; Cortical Synchronization; Dise | 2006 |
Oxidative modification of DNA bases in rat liver and lung during chemical carcinogenesis and aging.
Topics: 2-Acetylaminofluorene; Adenine; Aging; Animals; Antineoplastic Agents; Disease Models, Animal; DNA D | 1995 |
Prolonged epileptiform bursting induced by 0-Mg(2+) in rat hippocampal slices depends on gap junctional coupling.
Topics: Action Potentials; Anesthetics, Inhalation; Animals; Anti-Ulcer Agents; Carbenoxolone; Cell Communic | 2001 |