Page last updated: 2024-10-20

trimethylamine and Diabetes Mellitus, Type 2

trimethylamine has been researched along with Diabetes Mellitus, Type 2 in 6 studies

Diabetes Mellitus, Type 2: A subclass of DIABETES MELLITUS that is not INSULIN-responsive or dependent (NIDDM). It is characterized initially by INSULIN RESISTANCE and HYPERINSULINEMIA; and eventually by GLUCOSE INTOLERANCE; HYPERGLYCEMIA; and overt diabetes. Type II diabetes mellitus is no longer considered a disease exclusively found in adults. Patients seldom develop KETOSIS but often exhibit OBESITY.

Research Excerpts

ExcerptRelevanceReference
"Betaine is highly individual in overweight people with diabetes."9.20Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. ( Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S, 2015)
"Betaine is highly individual in overweight people with diabetes."5.20Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period. ( Chambers, ST; Elmslie, JL; Florkowski, CM; George, PM; Krebs, JD; Lever, M; Lunt, H; McEntyre, CJ; Slow, S, 2015)
"The relationship between sodium glucose co-transporter 2 inhibitors (SGLT2i) and trimethylamine N-oxide (TMAO) following acute myocardial infarction (AMI) is not yet explored."4.31Alterations in trimethylamine-N-oxide in response to Empagliflozin therapy: a secondary analysis of the EMMY trial. ( Aziz, F; Curcic, P; Hermann, M; Kolesnik, E; Mangge, H; Meinitzer, A; Pferschy, PN; Sourij, H; Tripolt, NJ; von Lewinski, D, 2023)
"Historically, the focus of type II diabetes mellitus (T2DM) research has been on host metabolism and hormone action."2.72The Gut Microbial Endocrine Organ in Type 2 Diabetes. ( Brown, JM; Massey, W, 2021)
"Incident type 2 diabetes was ascertained during follow-up visits."1.72Serum trimethylamine-N-oxide is associated with incident type 2 diabetes in middle-aged and older adults: a prospective cohort study. ( Chen, S; Chen, YM; Fang, AP; Huang, BX; Huang, RZ; Huang, ZH; Li, SY; Lin, XL; Lu, XT; Ma, JF; Zhu, HL, 2022)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (33.33)24.3611
2020's4 (66.67)2.80

Authors

AuthorsStudies
Li, SY1
Chen, S1
Lu, XT1
Fang, AP1
Chen, YM1
Huang, RZ1
Lin, XL1
Huang, ZH1
Ma, JF1
Huang, BX1
Zhu, HL1
Aziz, F1
Tripolt, NJ1
Pferschy, PN1
Kolesnik, E1
Mangge, H1
Curcic, P1
Hermann, M1
Meinitzer, A1
von Lewinski, D1
Sourij, H1
Winther, SA1
Rossing, P1
Massey, W1
Brown, JM1
Grabowska-Polanowska, B1
Skowron, M1
Miarka, P1
Pietrzycka, A1
ƚliwka, I1
McEntyre, CJ1
Lever, M1
Chambers, ST1
George, PM1
Slow, S1
Elmslie, JL1
Florkowski, CM1
Lunt, H1
Krebs, JD1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Guangzhou Nutrition and Health Study (GNHS): A Multiomics-based Study[NCT03179657]5,118 participants (Actual)Observational2008-07-01Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for trimethylamine and Diabetes Mellitus, Type 2

ArticleYear
The Gut Microbial Endocrine Organ in Type 2 Diabetes.
    Endocrinology, 2021, 02-01, Volume: 162, Issue:2

    Topics: Amino Acids, Aromatic; Bile Acids and Salts; Diabetes Mellitus, Type 2; Endocrine System; Fatty Acid

2021

Trials

1 trial available for trimethylamine and Diabetes Mellitus, Type 2

ArticleYear
Variation of betaine, N,N-dimethylglycine, choline, glycerophosphorylcholine, taurine and trimethylamine-N-oxide in the plasma and urine of overweight people with type 2 diabetes over a two-year period.
    Annals of clinical biochemistry, 2015, Volume: 52, Issue:Pt 3

    Topics: Aged; Betaine; Choline; Diabetes Mellitus, Type 2; Female; Glycerylphosphorylcholine; Humans; Male;

2015

Other Studies

4 other studies available for trimethylamine and Diabetes Mellitus, Type 2

ArticleYear
Serum trimethylamine-N-oxide is associated with incident type 2 diabetes in middle-aged and older adults: a prospective cohort study.
    Journal of translational medicine, 2022, 08-18, Volume: 20, Issue:1

    Topics: Aged; Blood Glucose; Diabetes Mellitus, Type 2; Glycated Hemoglobin; Humans; Insulin; Methylamines;

2022
Alterations in trimethylamine-N-oxide in response to Empagliflozin therapy: a secondary analysis of the EMMY trial.
    Cardiovascular diabetology, 2023, 07-20, Volume: 22, Issue:1

    Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Male; Middle Aged; Myocardial Infarction; Oxides; S

2023
TMAO: Trimethylamine-N-Oxide or Time to Minimize Intake of Animal Products?
    The Journal of clinical endocrinology and metabolism, 2020, 12-01, Volume: 105, Issue:12

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Methylamines; Oxides; Plasma

2020
The application of chromatographic breath analysis in the search of volatile biomarkers of chronic kidney disease and coexisting type 2 diabetes mellitus.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2017, Aug-15, Volume: 1060

    Topics: Acetone; Adult; Biomarkers; Butadienes; Case-Control Studies; Diabetes Mellitus, Type 2; Exhalation;

2017