trimethylamine and Cardiovascular Diseases

trimethylamine has been researched along with Cardiovascular Diseases in 39 studies

Research

Studies (39)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (2.56)29.6817
2010's15 (38.46)24.3611
2020's23 (58.97)2.80

Authors

AuthorsStudies
Chang, D; Dong, J; Ma, T; Nie, J; Xu, X; Yang, Z1
Drapała, A; Grzywacz, T; Karwowski, WJ; Konop, M; Kłodzińska, EM; Laskowska, AK; Nowiński, A; Rybka, M; Waraksa, E1
Chen, G; Dou, X; He, L; Liu, T1
Bo, Y; Bogaert, D; Cai, X; Chen, J; Fang, A; He, D; He, Y; Larsson, SC; Li, D; Li, X; Lu, Y; Song, P; Theodoratou, E; Tsilidis, K; Wu, Q; Yu, H; Yuan, S; Zhu, H; Zhu, Y1
Abecia, L; Anguita, J; Fornari, T; García-Cañas, V; García-Risco, MR; Peña-Cearra, A; Rodríguez, H; Simó, C1
Bean, LD; Harris, RE; Milks, MW; Raman, SV; Smart, SM; Wing, JJ1
Ren, Y; Wang, Z; Xue, J1
Bode, LM; Eggers, M; Jahn, D; Jasper, J; Lubitz, W; Moser, J; Neubauer, K; Piskol, F; Reijerse, E; Slusarenko, A1
Buawangpong, N; Chattipakorn, N; Chattipakorn, SC; Chindapan, N; Devahastin, S; Phrommintikul, A; Pinyopornpanish, K1
Blanco, R; Daimiel, L; Dávalos, A; Díez-Ricote, L; Micó, V; Ordovás, JM; Ruiz-Valderrey, P; Tomé-Carneiro, J1
Huang, Y; Liu, J; Peng, L; Tang, C; Wang, H; Wei, X; Yuan, X1
An, JP; Lee, H; Liu, X; Wang, Y1
Bielak-Zmijewska, A; Grochowska, M; Hutsch, T; Jaworska, K; Konop, M; Mosieniak, G; Perlejewski, K; Radkowski, M; Sikora, E; Ufnal, M1
Bielak-Zmijewska, A; Filipiak, K; Gasecka, A; Hering, D; Hołyst, R; Jaworska, K; Kapłon-Cieślicka, A; Konwerski, M; Mosieniak, G; Pilz, M; Sikora, E; Ufnal, M1
Dai, Q; Liu, Y; Zhang, H1
Arnal, ME; Brugère, JF; Camponova, P; Fadhlaoui, K; Martineau, M; O'Toole, PW; Ollivier, B1
von Eckardstein, A1
Rossing, P; Winther, SA1
Chen, C; He, Y; Huang, Z; Lei, W; Liang, Z; Luo, H; Qi, Y; Shui, X; Zhu, Y1
Allison, J; Arboleya, S; Arias, JL; Arias, N; Gueimonde, M; Higarza, SG; Kaliszewska, A1
Anderson, CAM; Bradley, R1
He, M; Liu, Y; Tan, CP; Xu, YJ1
Mueller, NT; Tilves, C1
He, S; Jiang, H; Jiang, W; Zhuo, C1
Bordoni, L; Gabbianelli, R; Kalinowski, L; Lewicki, L; Olek, RA; Pelikant-Malecka, I; Petracci, I; Piangerelli, M; Radulska, A; Samulak, JJ1
Chen, ZY; He, Z1
Aadland, EK; Bertram, HC; Brejnrod, AD; Eng, Ø; Graff, IE; Holthe, A; Jacques, H; Kiilerich, P; Kristiansen, K; Lavigne, C; Liaset, B; Mellgren, G; Schmedes, M; Sundekilde, UK; Young, JF1
Allayee, H; Buffa, JA; Cajka, T; DiDonato, JA; Fiehn, O; Gu, X; Han, Y; Hartiala, JA; Hazen, SL; Hurd, AG; Kerby, RL; Li, L; Li, XS; Lüscher, TF; Nemet, I; Obeid, S; Rey, FE; Roberts, AB; Romano, KA; Shahen, CJ; Skye, SM; Tang, WHW; Wagner, MA; Wang, Z; Wu, Y1
Chen, Y; Jameson, E; Quareshy, M1
Kris-Etherton, PM; Petersen, KS; Tindall, AM1
Bry, L; Crothers, J1
Miller, MJ1
Arduini, A; Lopaschuk, GD; Ussher, JR1
Hazen, SL; Tang, WH1
Kirsop, J; Li, D; Tang, WH1
Awwad, HM; Geisel, J; Graeber, S; Herrmann, W; Obeid, R; Rabagny, Y1
Fennema, D; Phillips, IR; Shephard, EA1
Fricker, G; Garbade, SF; Kratzer, F; Langhans, CD; Okun, JG; Schmidt, KV; Schuhmann, V; Stremmel, W1
Dolan, C; Lambert, DM; O'Brien, E; O'Brien, JK; Shields, DC; Stanton, A; Treacy, EP1

Reviews

14 review(s) available for trimethylamine and Cardiovascular Diseases

ArticleYear
Association of Trimethylamine-N-Oxide Levels with Risk of Cardiovascular Disease and Mortality among Elderly Subjects: A Systematic Review and Meta-Analysis.
    Cardiorenal medicine, 2022, Volume: 12, Issue:2

    Topics: Aged; Biomarkers; Cardiovascular Diseases; Heart Failure; Humans; Methylamines; Oxides; Prospective Studies; Renal Insufficiency, Chronic; Risk Factors

2022
Gut microbiota-derived metabolite trimethylamine-N-oxide and multiple health outcomes: an umbrella review and updated meta-analysis.
    The American journal of clinical nutrition, 2022, 07-06, Volume: 116, Issue:1

    Topics: Cardiovascular Diseases; Diabetes Mellitus; Gastrointestinal Microbiome; Humans; Hypertension; Methylamines; Neoplasms; Oxides; Risk Factors

2022
[Gut-derived uremic toxin trimethylamine-N-oxide in cardiovascular disease under end-stage renal disease: an injury mechanism and therapeutic target].
    Sheng wu yi xue gong cheng xue za zhi = Journal of biomedical engineering = Shengwu yixue gongchengxue zazhi, 2022, Aug-25, Volume: 39, Issue:4

    Topics: Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Methylamines; Oxides; Uremic Toxins

2022
Archaea, specific genetic traits, and development of improved bacterial live biotherapeutic products: another face of next-generation probiotics.
    Applied microbiology and biotechnology, 2020, Volume: 104, Issue:11

    Topics: Animals; Archaea; Biological Therapy; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Humans; Metabolism, Inborn Errors; Methylamines; Mice; Probiotics

2020
Gut microbiota metabolites as integral mediators in cardiovascular diseases (Review).
    International journal of molecular medicine, 2020, Volume: 46, Issue:3

    Topics: Amino Acids; Animals; Bile Acids and Salts; Cardiovascular Diseases; Fatty Acids; Gastrointestinal Microbiome; Humans; Metabolic Networks and Pathways; Methylamines; Risk Factors

2020
The Relationship between Choline Bioavailability from Diet, Intestinal Microbiota Composition, and Its Modulation of Human Diseases.
    Nutrients, 2020, Aug-05, Volume: 12, Issue:8

    Topics: Animals; Biological Availability; Cardiovascular Diseases; Choline; Diet; Dysbiosis; Gastrointestinal Microbiome; Genotype; Humans; Inflammatory Bowel Diseases; Liver; Methylamines; Non-alcoholic Fatty Liver Disease; Renal Insufficiency, Chronic

2020
Gut microbiota-derived trimethylamine-N-oxide: A bridge between dietary fatty acid and cardiovascular disease?
    Food research international (Ottawa, Ont.), 2020, Volume: 138, Issue:Pt B

    Topics: Cardiovascular Diseases; Fatty Acids; Gastrointestinal Microbiome; Humans; Methylamines; Oxides

2020
Trimethylamine/Trimethylamine-N-Oxide as a Key Between Diet and Cardiovascular Diseases.
    Cardiovascular toxicology, 2021, Volume: 21, Issue:8

    Topics: Animals; Bacteria; Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Heart Disease Risk Factors; Humans; Methylamines; Risk Assessment

2021
Methodological considerations for the identification of choline and carnitine-degrading bacteria in the gut.
    Methods (San Diego, Calif.), 2018, 10-01, Volume: 149

    Topics: Amino Acid Sequence; Cardiovascular Diseases; Carnitine; Choline; Computational Biology; Diet; Gastrointestinal Microbiome; Humans; Klebsiella pneumoniae; Methylamines; Proteus mirabilis

2018
Dietary Patterns Affect the Gut Microbiome-The Link to Risk of Cardiometabolic Diseases.
    The Journal of nutrition, 2018, 09-01, Volume: 148, Issue:9

    Topics: Bacteria; Bile Acids and Salts; Cardiovascular Diseases; Diet; Diet, Mediterranean; Diet, Vegetarian; Fatty Acids, Volatile; Gastrointestinal Microbiome; Humans; Metabolic Diseases; Methylamines; Risk Factors

2018
Gut microbiota metabolism of L-carnitine and cardiovascular risk.
    Atherosclerosis, 2013, Volume: 231, Issue:2

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Diet; Dietary Supplements; Humans; Insulin Resistance; Intestines; Liver; Methylamines; Mice; Microbiota; Muscle, Skeletal; Myocardial Ischemia; Phosphatidylcholines; Risk

2013
The contributory role of gut microbiota in cardiovascular disease.
    The Journal of clinical investigation, 2014, Volume: 124, Issue:10

    Topics: Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Choline; Diet; Female; Food; Humans; Intestines; Male; Methylamines; Microbiota; Oxygenases; Phosphatidylcholines

2014
Listening to Our Gut: Contribution of Gut Microbiota and Cardiovascular Risk in Diabetes Pathogenesis.
    Current diabetes reports, 2015, Volume: 15, Issue:9

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus; Diet; Gastrointestinal Microbiome; Humans; Methylamines; Risk Factors

2015
Trimethylamine and Trimethylamine N-Oxide, a Flavin-Containing Monooxygenase 3 (FMO3)-Mediated Host-Microbiome Metabolic Axis Implicated in Health and Disease.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:11

    Topics: Animals; Cardiovascular Diseases; Gastrointestinal Microbiome; Host-Pathogen Interactions; Humans; Methylamines; Oxygenases

2016

Trials

1 trial(s) available for trimethylamine and Cardiovascular Diseases

ArticleYear
The Effect of Lean-Seafood and Non-Seafood Diets on Fecal Metabolites and Gut Microbiome: Results from a Randomized Crossover Intervention Study.
    Molecular nutrition & food research, 2019, Volume: 63, Issue:1

    Topics: Adolescent; Adult; Aged; Cardiovascular Diseases; Cross-Over Studies; Diet; Feces; Female; Gastrointestinal Microbiome; Humans; Male; Metabolome; Methylamines; Middle Aged; Risk Factors; Seafood

2019

Other Studies

24 other study(ies) available for trimethylamine and Cardiovascular Diseases

ArticleYear
Trimethylamine-N-oxide (TMAO) and clinical outcomes in patients with end-stage kidney disease receiving peritoneal dialysis.
    Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis, 2022, Volume: 42, Issue:6

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Kidney Failure, Chronic; Oxides; Peritoneal Dialysis; Peritonitis; Prospective Studies; Retrospective Studies; Risk Factors

2022
Electrophoretic Determination of Trimethylamine (TMA) in Biological Samples as a Novel Potential Biomarker of Cardiovascular Diseases Methodological Approach.
    International journal of environmental research and public health, 2021, 11-23, Volume: 18, Issue:23

    Topics: Biomarkers; Cardiovascular Diseases; Gastrointestinal Microbiome; Humans; Methylamines

2021
Resazurin-based high-throughput screening method for the discovery of dietary phytochemicals to target microbial transformation of L-carnitine into trimethylamine, a gut metabolite associated with cardiovascular disease.
    Food & function, 2022, May-23, Volume: 13, Issue:10

    Topics: Cardiovascular Diseases; Carnitine; Gastrointestinal Microbiome; High-Throughput Screening Assays; Humans; Methylamines; Oxazines; Phytochemicals; Xanthenes

2022
Transferrin predicts trimethylamine-N-oxide levels and is a potential biomarker of cardiovascular disease.
    BMC cardiovascular disorders, 2022, 05-10, Volume: 22, Issue:1

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Methylamines; Oxides; Transferrin

2022
Two-component carnitine monooxygenase from Escherichia coli: functional characterization, inhibition and mutagenesis of the molecular interface.
    Bioscience reports, 2022, 09-30, Volume: 42, Issue:9

    Topics: Cardiovascular Diseases; Carnitine; Disulfides; Escherichia coli; Flavin Mononucleotide; Humans; Methylamines; Methylhydrazines; Mixed Function Oxygenases; Mutagenesis; Oxidoreductases; Oxygenases; Sulfinic Acids

2022
Increased plasma trimethylamine-
    Food & function, 2022, Oct-03, Volume: 13, Issue:19

    Topics: Aged; Biomarkers; Blood Glucose; Cardiovascular Diseases; Cognitive Dysfunction; Heart Disease Risk Factors; Humans; Lipids; Methylamines; Middle Aged; Oxides; Risk Factors

2022
TMAO Upregulates Members of the miR-17/92 Cluster and Impacts Targets Associated with Atherosclerosis.
    International journal of molecular sciences, 2022, Oct-11, Volume: 23, Issue:20

    Topics: Animals; Atherosclerosis; Betaine; Cardiovascular Diseases; Carnitine; Choline; Humans; Inflammation; Methylamines; Mice; MicroRNAs

2022
Association of Circulating Trimethylamine-N Oxide With Malnutrition and the Risk of Coronary Artery Disease in Patients With Maintenance Hemodialysis.
    Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation, 2023, Volume: 33, Issue:3

    Topics: Cardiovascular Diseases; Coronary Artery Disease; Humans; Malnutrition; Oxides; Renal Dialysis

2023
Identification of Polymethoxyflavones (PMFs) from Orange Peel and Their Inhibitory Effects on the Formation of Trimethylamine (TMA) and Trimethylamine-N-oxide (TMAO) Using cntA/B and cutC/D Enzymes and Molecular Docking.
    Journal of agricultural and food chemistry, 2023, Nov-01, Volume: 71, Issue:43

    Topics: Cardiovascular Diseases; Citrus sinensis; Methylamines; Molecular Docking Simulation; Oxides

2023
Trimethylamine But Not Trimethylamine Oxide Increases With Age in Rat Plasma and Affects Smooth Muscle Cells Viability.
    The journals of gerontology. Series A, Biological sciences and medical sciences, 2020, 06-18, Volume: 75, Issue:7

    Topics: Age Factors; Animals; Cardiovascular Diseases; Cell Culture Techniques; Cell Survival; Gastrointestinal Microbiome; Humans; Male; Methylamines; Myocytes, Smooth Muscle; Rats; Rats, Inbred WKY; Rats, Sprague-Dawley; Risk Factors

2020
TMA, A Forgotten Uremic Toxin, but Not TMAO, Is Involved in Cardiovascular Pathology.
    Toxins, 2019, 08-26, Volume: 11, Issue:9

    Topics: Adult; Aged; Animals; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cell Survival; Cells, Cultured; Female; Glomerular Filtration Rate; Healthy Volunteers; Humans; Male; Methylamines; Myocytes, Cardiac; Rats

2019
[Trimethylamine-N-oxide and cardiovascular events in chronic kidney disease].
    Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences, 2019, Nov-28, Volume: 44, Issue:11

    Topics: Biomarkers; Cardiovascular Diseases; Humans; Methylamines; Oxides; Renal Insufficiency, Chronic

2019
Trimethyllysine and trimethylamine-N-oxide - pathogenic factors or surrogate markers of increased cardiovascular disease risk?
    Journal of internal medicine, 2020, Volume: 288, Issue:4

    Topics: Biomarkers; Cardiovascular Diseases; Coronary Disease; Humans; Lysine; Methylamines; Myocardial Infarction; Oxides; Virulence Factors

2020
TMAO: Trimethylamine-N-Oxide or Time to Minimize Intake of Animal Products?
    The Journal of clinical endocrinology and metabolism, 2020, 12-01, Volume: 105, Issue:12

    Topics: Animals; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Humans; Methylamines; Oxides; Plasma

2020
The potential of novel plant protein foods to improve dietary patterns and markers of cardiovascular health.
    The American journal of clinical nutrition, 2020, 11-11, Volume: 112, Issue:5

    Topics: Adult; Animals; Cardiovascular Diseases; Cross-Over Studies; Humans; Meat; Methylamines; Oxides; Risk Factors

2020
Trimethylamine N-oxide variation in humans: the product of a diet-microbiota interaction?
    The American journal of clinical nutrition, 2021, 06-01, Volume: 113, Issue:6

    Topics: Cardiovascular Diseases; Diet; Gastrointestinal Microbiome; Hispanic or Latino; Humans; Methylamines; Microbiota; Oxides; Public Health

2021
Mitochondrial DNA copy number and trimethylamine levels in the blood: New insights on cardiovascular disease biomarkers.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2021, Volume: 35, Issue:7

    Topics: Aged; Biomarkers; Cardiovascular Diseases; Case-Control Studies; Cohort Studies; DNA Copy Number Variations; DNA, Mitochondrial; Female; Gastrointestinal Tract; Humans; Male; Methylamines; Risk Factors

2021
What Are Missing Parts in the Research Story of Trimethylamine-N-oxide (TMAO)?
    Journal of agricultural and food chemistry, 2017, Jul-05, Volume: 65, Issue:26

    Topics: Animals; Cardiovascular Diseases; Cattle; Gastrointestinal Microbiome; Humans; Intestinal Mucosa; Intestines; Methylamines; Red Meat

2017
Untargeted metabolomics identifies trimethyllysine, a TMAO-producing nutrient precursor, as a predictor of incident cardiovascular disease risk.
    JCI insight, 2018, 03-22, Volume: 3, Issue:6

    Topics: Aged; Animals; Atherosclerosis; Cardiovascular Diseases; Carnitine; Cholesterol; Choline; Disease Models, Animal; Feces; Female; Gastrointestinal Microbiome; Genome-Wide Association Study; Humans; Lysine; Male; Metabolomics; Methylamines; Mice; Mice, Inbred C57BL; Middle Aged; Nutrients; Risk Factors; Thrombosis

2018
Gutting TMA to Save the Heart.
    Cell host & microbe, 2018, 10-10, Volume: 24, Issue:4

    Topics: Animals; Cardiovascular Diseases; Choline; Diet; Gastrointestinal Microbiome; Gastrointestinal Tract; Host Microbial Interactions; Humans; Methylamines; Mice; Mice, Knockout

2018
Risk factors for cardiovascular disease: a cautionary tale of diet-microbiome interactions.
    Journal of the American College of Nutrition, 2013, Volume: 32, Issue:2

    Topics: Cardiovascular Diseases; Carnitine; Choline; Diet; Gastrointestinal Tract; Humans; Methylamines; Microbiota; Risk Factors

2013
Plasma trimethylamine N-oxide concentration is associated with choline, phospholipids, and methyl metabolism.
    The American journal of clinical nutrition, 2016, Volume: 103, Issue:3

    Topics: Aged; Bacteria; Betaine; Cardiovascular Diseases; Choline; Creatinine; Diabetes Mellitus; Female; Gastrointestinal Microbiome; Humans; Lipoproteins, HDL; Male; Methylamines; Methylation; Middle Aged; Phosphatidylcholines; Phospholipids; S-Adenosylhomocysteine; S-Adenosylmethionine; Sex Factors

2016
Blood Trimethylamine-N-Oxide Originates from Microbiota Mediated Breakdown of Phosphatidylcholine and Absorption from Small Intestine.
    PloS one, 2017, Volume: 12, Issue:1

    Topics: Aged; Cardiovascular Diseases; Gas Chromatography-Mass Spectrometry; Humans; Intestine, Small; Male; Methylamines; Microbiota; Mixed Function Oxygenases; Oxides; Phosphatidylcholines; Rifamycins; Rifaximin; Risk Factors; Spectrometry, Mass, Electrospray Ionization

2017
Polymorphisms of the Flavin containing monooxygenase 3 (FMO3) gene do not predispose to essential hypertension in Caucasians.
    BMC medical genetics, 2005, Dec-02, Volume: 6

    Topics: Adult; Aged; Aged, 80 and over; Cardiovascular Diseases; Case-Control Studies; Genetic Predisposition to Disease; Genotype; Haplotypes; Humans; Hypertension; Metabolism, Inborn Errors; Methylamines; Middle Aged; Mutation, Missense; Oxygenases; Polymorphism, Genetic; Risk Factors; White People

2005