trimethoprim has been researched along with Vesicoureteral Reflux in 24 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| " They were aged 2-12 years at the start of prophylaxis which was given in a daily dose of approximately 10 mg sulphamethoxazole (SMX) and 2 mg trimethoprim (TMP)/kg body weight for at least 6 months and for up to 6 years." | 3.66 | Normal somatic growth in children receiving low-dose prophylactic co-trimoxazole. ( Paton, AM; Preece, MA; Smellie, JM, 1983) |
| "Since risk of renal scarring is believed to occur more frequently in young people, and since recurrent urinary infections mainly affect girls, the age and sex of subjects are important in the design of a prophylactic regimen." | 2.40 | Antibacterial prophylaxis in children with urinary tract infection. ( Bollgren, I, 1999) |
| "When pyelonephritis was present, piglets were randomized to receive either standard antibiotics or antibiotics and 2 mg." | 1.30 | Adjunctive oral corticosteroids reduce renal scarring: the piglet model of reflux and acute experimental pyelonephritis. ( Chandra, R; Majd, M; Park, JS; Pohl, HG; Rushton, HG, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (62.50) | 18.7374 |
| 1990's | 4 (16.67) | 18.2507 |
| 2000's | 4 (16.67) | 29.6817 |
| 2010's | 1 (4.17) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shaikh, N | 1 |
| Hoberman, A | 1 |
| Keren, R | 1 |
| Ivanova, A | 1 |
| Gotman, N | 1 |
| Chesney, RW | 1 |
| Carpenter, MA | 1 |
| Moxey-Mims, M | 1 |
| Wald, ER | 1 |
| Lidefelt, KJ | 1 |
| Herthelius, M | 1 |
| Hausmann, R | 1 |
| Ismaili, K | 1 |
| Hall, M | 1 |
| Piepsz, A | 1 |
| Wissing, KM | 1 |
| Collier, F | 1 |
| Schulman, C | 1 |
| Avni, FE | 1 |
| Grasso, M | 1 |
| Torelli, F | 1 |
| Blanco, S | 1 |
| Fortuna, F | 1 |
| Baruffi, M | 1 |
| Smellie, JM | 5 |
| Asscher, AW | 1 |
| Witherington, R | 1 |
| Branan, WJ | 1 |
| Wray, BB | 1 |
| Best, GK | 1 |
| Preece, MA | 1 |
| Paton, AM | 1 |
| Koff, SA | 1 |
| Murtagh, DS | 1 |
| Scott, JE | 1 |
| Swallow, V | 1 |
| Coulthard, MG | 1 |
| Lambert, HJ | 1 |
| Lee, RE | 1 |
| Pohl, HG | 1 |
| Rushton, HG | 1 |
| Park, JS | 1 |
| Chandra, R | 1 |
| Majd, M | 1 |
| Bollgren, I | 1 |
| Savage, DC | 1 |
| Howie, G | 1 |
| Adler, K | 1 |
| Wilson, MI | 1 |
| Friedland, GW | 1 |
| Grüneberg, RN | 2 |
| Leakey, A | 1 |
| Atkin, WS | 1 |
| Servadio, C | 1 |
| Normand, IC | 1 |
| Gordon, AC | 1 |
| Thomas, DF | 1 |
| Arthur, RJ | 1 |
| Irving, HC | 1 |
| Smith, SE | 1 |
| Hanson, E | 1 |
| Hansson, S | 1 |
| Jodal, U | 1 |
| Belman, AB | 1 |
| Skoog, SJ | 1 |
| Bantock, HM | 1 |
| Prescod, N | 1 |
| Leumann, EP | 1 |
| Anders, D | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Evaluation of the Effectiveness of Antibiotic Prophylaxis in Children With a History of Upper Urinary Tract Infections:a Multicentre Randomised Study[NCT00156546] | Phase 4 | 660 participants | Interventional | 2000-05-31 | Active, not recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for trimethoprim and Vesicoureteral Reflux
| Article | Year |
|---|---|
Antibacterial prophylaxis in children with urinary tract infection.
Topics: Anti-Infective Agents, Urinary; Child; Cicatrix; Drug Resistance, Microbial; Female; Humans; Infant; | 1999 |
Recurrent urinary tract infections in infants and children.
Topics: Bacteriuria; Child; Child, Preschool; Coitus; Female; Humans; Infant; Male; New Zealand; Nitrofurant | 1977 |
[Recent aspects in urinary tract infections in children (author's transl)].
Topics: Ampicillin; Bacteriuria; Carbenicillin; Child, Preschool; Drug Combinations; Escherichia coli; Genta | 1974 |
4 trials available for trimethoprim and Vesicoureteral Reflux
| Article | Year |
|---|---|
Predictors of Antimicrobial Resistance among Pathogens Causing Urinary Tract Infection in Children.
Topics: Amoxicillin; Anti-Infective Agents; Cephalosporins; Child; Child, Preschool; Drug Resistance, Bacter | 2016 |
Antenatal hydronephrosis: infants with minor postnatal dilatation do not need prophylaxis.
Topics: Anti-Infective Agents, Urinary; Child, Preschool; Female; Follow-Up Studies; Humans; Hydronephrosis; | 2008 |
Screening of newborn babies for familial ureteric reflux.
Topics: Female; Genetic Linkage; Humans; Infant, Newborn; Kidney; Male; Neonatal Screening; Pregnancy; Radio | 1997 |
Controlled trial of therapy in covert bacteriuria of childhood.
Topics: Ampicillin; Bacteriuria; Child; Child, Preschool; Clinical Trials as Topic; Drug Therapy, Combinatio | 1975 |
17 other studies available for trimethoprim and Vesicoureteral Reflux
| Article | Year |
|---|---|
[Vesicoureteral reflux. Waiting attitude as the initial measure is significant].
Topics: Age Factors; Child, Preschool; Female; Follow-Up Studies; Humans; Hydronephrosis; Infant; Infant, Ne | 2003 |
Primary vesicoureteral reflux detected in neonates with a history of fetal renal pelvis dilatation: a prospective clinical and imaging study.
Topics: Anti-Infective Agents, Urinary; Antibiotic Prophylaxis; Chelating Agents; Chromium Radioisotopes; Ed | 2006 |
Lazy bladder syndrome (the infrequent voider) causing a vesicoureteral reflux in the child.
Topics: Algorithms; Anti-Infective Agents, Urinary; Child, Preschool; Female; Humans; Syndrome; Treatment Ou | 2007 |
[Preventive antibiotic therapy of recurring urinary tract infections in children].
Topics: Child; Child, Preschool; Female; Humans; Infant; Male; Methenamine; Nalidixic Acid; Nitrofurantoin; | 1981 |
Urinary tract infection.
Topics: Adolescent; Adult; Aged; Bacteriuria; Child; Child, Preschool; Cystitis; Escherichia coli; Female; F | 1981 |
Malacoplakia associated with vesicoureteral reflux and selective immunoglobulin A deficiency.
Topics: Anti-Infective Agents, Urinary; Bethanechol; Bethanechol Compounds; Child, Preschool; Drug Combinati | 1984 |
Normal somatic growth in children receiving low-dose prophylactic co-trimoxazole.
Topics: Body Height; Body Weight; Child; Child, Preschool; Drug Combinations; Female; Growth; Humans; Sulfam | 1983 |
The uninhibited bladder in children: effect of treatment on recurrence of urinary infection and on vesicoureteral reflux resolution.
Topics: Adolescent; Anti-Infective Agents, Urinary; Child; Child, Preschool; Drug Combinations; Female; Huma | 1983 |
Adjunctive oral corticosteroids reduce renal scarring: the piglet model of reflux and acute experimental pyelonephritis.
Topics: Acute Disease; Animals; Anti-Infective Agents, Urinary; Cicatrix; Drug Therapy, Combination; Glucoco | 1999 |
Long-term low-dose co-trimoxazole in prophylaxis of childhood urinary tract infection: clinical aspects.
Topics: Child; Child, Preschool; Drug Combinations; Female; Follow-Up Studies; Hematologic Diseases; Humans; | 1976 |
Conservative vs. surgical treatment of vesicoureteral reflux.
Topics: Adolescent; Adult; Age Factors; Ampicillin; Child; Child, Preschool; Female; Humans; Infant; Kidney | 1975 |
Bacteriuria, reflux, and renal scarring.
Topics: Anti-Bacterial Agents; Bacteriuria; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn | 1975 |
Prenatally diagnosed reflux: a follow-up study.
Topics: Female; Fetal Diseases; Follow-Up Studies; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Diagno | 1990 |
Trimethoprim-sulphadiazine prophylaxis in children with vesico-ureteric reflux.
Topics: Anti-Infective Agents, Urinary; Child; Child, Preschool; Drug Combinations; Drug Resistance, Microbi | 1989 |
Nonsurgical approach to the management of vesicoureteral reflux in children.
Topics: Anti-Infective Agents; Child; Child, Preschool; Creatinine; Drug Combinations; Female; Humans; Infan | 1989 |
Prophylactic co-trimoxazole and trimethoprim in the management of urinary tract infection in children.
Topics: Child; Drug Resistance, Microbial; Enterobacteriaceae; Female; Humans; Intestines; Male; Patient Com | 1988 |
[Urinary tract infections in childhood].
Topics: Anti-Infective Agents, Urinary; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; | 1988 |