trimethoprim has been researched along with Uremia in 5 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Uremia: A clinical syndrome associated with the retention of renal waste products or uremic toxins in the blood. It is usually the result of RENAL INSUFFICIENCY. Most uremic toxins are end products of protein or nitrogen CATABOLISM, such as UREA or CREATININE. Severe uremia can lead to multiple organ dysfunctions with a constellation of symptoms.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Malmborg, AS | 1 |
| Rane, A | 1 |
| Lichtenwalner, DM | 1 |
| Suh, B | 1 |
| Lorber, B | 1 |
| Rudnick, MR | 1 |
| Craig, WA | 3 |
| Kunin, CM | 2 |
| Uehling, DT | 1 |
| Yuill, GM | 1 |
| Welling, PG | 1 |
| Amidon, GL | 1 |
5 other studies available for trimethoprim and Uremia
| Article | Year |
|---|---|
Comparative determination of sulfonamide concentration in serum by chemical and microbiological assay.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Child; Child, Preschool; Drug Resistance, Microbial; | 1984 |
Correction of drug binding defects in uremia in vitro by anion exchange resin treatment.
Topics: Adult; Aged; Anion Exchange Resins; Blood Proteins; Dialysis; Female; Humans; Hydrogen-Ion Concentra | 1982 |
Trimethoprim therapy for urinary tract infection. Long-term prophylaxis in a uremic patient.
Topics: Adult; Female; Humans; Proteus mirabilis; Recurrence; Time Factors; Trimethoprim; Uremia; Urinary Tr | 1978 |
Megaloblastic anaemia due to trimethoprim-sulphamethoxazole therapy in uraemia.
Topics: Adult; Anemia, Macrocytic; Anti-Infective Agents; Female; Folic Acid Antagonists; Humans; Pyrimidine | 1973 |
Pharmacokinetics of trimethoprim and sulfamethoxazole in normal subjects and in patients with renal failure.
Topics: Administration, Oral; Ammonium Chloride; Bicarbonates; Drug Combinations; Humans; Kidney Failure, Ch | 1973 |