trimethoprim has been researched along with Trypanosomiasis, African in 1 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Trypanosomiasis, African: A disease endemic among people and animals in Central Africa. It is caused by various species of trypanosomes, particularly T. gambiense and T. rhodesiense. Its second host is the TSETSE FLY. Involvement of the central nervous system produces African sleeping sickness. Nagana is a rapidly fatal trypanosomiasis of horses and other animals.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chowdhury, SF | 1 |
| Villamor, VB | 1 |
| Guerrero, RH | 1 |
| Leal, I | 1 |
| Brun, R | 1 |
| Croft, SL | 1 |
| Goodman, JM | 1 |
| Maes, L | 1 |
| Ruiz-Perez, LM | 1 |
| Pacanowska, DG | 1 |
| Gilbert, IH | 1 |
1 other study available for trimethoprim and Trypanosomiasis, African
| Article | Year |
|---|---|
Design, synthesis, and evaluation of inhibitors of trypanosomal and leishmanial dihydrofolate reductase.
Topics: Animals; Drug Design; Folic Acid Antagonists; Humans; In Vitro Techniques; Leishmania infantum; Leis | 1999 |