trimethoprim has been researched along with Toxoplasmosis, Congenital in 2 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Toxoplasmosis, Congenital: Prenatal protozoal infection with TOXOPLASMA gondii which is associated with injury to the developing fetal nervous system. The severity of this condition is related to the stage of pregnancy during which the infection occurs; first trimester infections are associated with a greater degree of neurologic dysfunction. Clinical features include HYDROCEPHALUS; MICROCEPHALY; deafness; cerebral calcifications; SEIZURES; and psychomotor retardation. Signs of a systemic infection may also be present at birth, including fever, rash, and hepatosplenomegaly. (From Adams et al., Principles of Neurology, 6th ed, p735)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ocular toxoplasmosis is a frequent cause of ocular inflammation which threatens central visual acuity." | 2.38 | [Treatment of ocular toxoplasmosis. Part 1: Basic principles and diagnosis]. ( Mittelviefhaus, H, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 1 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Nguyen, BT | 1 |
| Stadtsbaeder, S | 1 |
| Mittelviefhaus, H | 1 |
1 review available for trimethoprim and Toxoplasmosis, Congenital
| Article | Year |
|---|---|
[Treatment of ocular toxoplasmosis. Part 1: Basic principles and diagnosis].
Topics: Clindamycin; Humans; Infant; Infant, Newborn; Pyrimethamine; Toxoplasmosis, Congenital; Toxoplasmosi | 1993 |
1 other study available for trimethoprim and Toxoplasmosis, Congenital
| Article | Year |
|---|---|
[Therapeutic future of trimethoprim-sulfamethoxazole in toxoplasmosis].
Topics: Animals; Drug Combinations; Female; Humans; Mice; Pregnancy; Sulfamethoxazole; Toxoplasmosis; Toxopl | 1983 |