trimethoprim has been researched along with Symptom Cluster in 8 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "If the vasculitis is secondary to an underlying disease, such as lymphoma, therapy should be directed at the primary disease." | 2.37 | Pulmonary vasculitis. ( Fauci, AS; Leavitt, RY, 1986) |
| "The syndrome is characterised by fever, an itchy erythema with edema, confluent papules and purpura of the hands and feet in a "gloves and socks" distribution." | 1.30 | [Drug-induced papular-purpuric gloves and socks syndrome]. ( Ballmer-Weber, BK; Brand, CU; Hunziker, TK; van Rooijen, MM; Yawalkar, N, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Grasso, M | 1 |
| Torelli, F | 1 |
| Blanco, S | 1 |
| Fortuna, F | 1 |
| Baruffi, M | 1 |
| Nolph, MB | 1 |
| Dion, MW | 1 |
| van Rooijen, MM | 1 |
| Brand, CU | 1 |
| Ballmer-Weber, BK | 1 |
| Yawalkar, N | 1 |
| Hunziker, TK | 1 |
| Leavitt, RY | 1 |
| Fauci, AS | 1 |
| Bahemuka, M | 1 |
| Shemena, AR | 1 |
| Panayiotopoulos, CP | 1 |
| al-Aska, AK | 1 |
| Obeid, T | 1 |
| Daif, AK | 1 |
| Gossius, G | 1 |
| Vorland, L | 1 |
| First, LR | 1 |
| Smith, BR | 1 |
| Lipton, J | 1 |
| Nathan, DG | 1 |
| Parkman, R | 1 |
| Rappeport, JM | 1 |
| Tauchnitz, C | 1 |
| Ellorhaoui, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Azacitidine (AZA) Combined With N-Acetyl-L-cysteine (NAC) for Prolonged Isolated Thrombocytopenia (PIT) After Hematopoietic Stem Cell Transplantation (HSCT)[NCT05126004] | Phase 2 | 100 participants (Anticipated) | Interventional | 2021-12-01 | Not yet recruiting | ||
| A Prospective Study of Patients With Isolated Thrombocytopenia Following Hematopoietic Stem Cell Transplantation[NCT02487563] | Phase 3 | 97 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
The total number of megakaryocytes as well as the platelet-shedding megakaryocytes of bone marrow smears (per cm2) was counted and cross-checked by blinded observers. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment
| Intervention | cells/cm^2 (Median) |
|---|---|
| Experimental Group 1 | 6.7 |
| Experimental Group 2 | 7.5 |
| Control Group | 3.3 |
Platelet response refers to a sustained increase (stable or increasing level) of at least 30×10E9/L independent of transfusion for 3 days. (NCT02487563)
Timeframe: Up to 4 weeks after the treatment
| Intervention | Participants (Count of Participants) |
|---|---|
| Experimental Group 1 | 20 |
| Experimental Group 2 | 22 |
| Control Group | 6 |
1 review available for trimethoprim and Symptom Cluster
| Article | Year |
|---|---|
Pulmonary vasculitis.
Topics: Adrenal Cortex Hormones; Azathioprine; Behcet Syndrome; Chlorambucil; Connective Tissue Diseases; Cy | 1986 |
1 trial available for trimethoprim and Symptom Cluster
| Article | Year |
|---|---|
[Acute dysuria/pollakisuria syndrome in women].
Topics: Acute Disease; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Administration | 1986 |
6 other studies available for trimethoprim and Symptom Cluster
| Article | Year |
|---|---|
Lazy bladder syndrome (the infrequent voider) causing a vesicoureteral reflux in the child.
Topics: Algorithms; Anti-Infective Agents, Urinary; Child, Preschool; Female; Humans; Syndrome; Treatment Ou | 2007 |
Raeder's syndrome associated with internal carotid artery dilation and sinusitis.
Topics: Adult; Carotid Artery Diseases; Carotid Artery, Internal; Dilatation, Pathologic; Facial Neuralgia; | 1982 |
[Drug-induced papular-purpuric gloves and socks syndrome].
Topics: Aged; Edema; Erythema; Foot Dermatoses; Hand Dermatoses; Humans; Male; Pruritus; Purpura; Skin Disea | 1999 |
Neurological syndromes of brucellosis.
Topics: Adult; Brucella abortus; Brucellosis; Cerebrovascular Disorders; Drug Combinations; Drug Resistance, | 1988 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
Isolated thrombocytopenia after allogeneic bone marrow transplantation: existence of transient and chronic thrombocytopenic syndromes.
Topics: Actuarial Analysis; Adolescent; Adult; Azathioprine; Bone Marrow; Bone Marrow Transplantation; Child | 1985 |
[Antibacterial chemotherapy of the chronic bronchitis syndrome].
Topics: Ampicillin; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Carbenicillin; Cephalosporins; | 1974 |