trimethoprim has been researched along with Short Bowel Syndrome in 2 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Short Bowel Syndrome: A malabsorption syndrome resulting from extensive operative resection of the SMALL INTESTINE, the absorptive region of the GASTROINTESTINAL TRACT.
| Excerpt | Relevance | Reference |
|---|---|---|
| " JI, JC, and sham piglets commenced parenteral nutrition on day 0 and received ampicillin and trimethoprim-sulfadoxine on days 0-4 for prevention of line sepsis." | 3.85 | In a Neonatal Piglet Model of Intestinal Failure, Administration of Antibiotics and Lack of Enteral Nutrition Have a Greater Impact on Intestinal Microflora Than Surgical Resection Alone. ( Levesque, CL; Li, J; Lim, D; St Pierre, B; Turner, J; Wales, P; Wizzard, P, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Levesque, CL | 1 |
| Turner, J | 1 |
| Li, J | 1 |
| Wizzard, P | 1 |
| St Pierre, B | 1 |
| Lim, D | 1 |
| Wales, P | 1 |
| Menardi, G | 1 |
| Guggenbichler, JP | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Absorption of Antibiotics With High Oral Bioavailability in Short-bowel Syndrome : a Monocentric Pilot Study[NCT05302531] | Phase 1 | 10 participants (Anticipated) | Interventional | 2022-12-09 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 other studies available for trimethoprim and Short Bowel Syndrome
| Article | Year |
|---|---|
In a Neonatal Piglet Model of Intestinal Failure, Administration of Antibiotics and Lack of Enteral Nutrition Have a Greater Impact on Intestinal Microflora Than Surgical Resection Alone.
Topics: Ampicillin; Animals; Animals, Newborn; Anti-Bacterial Agents; Disease Models, Animal; DNA, Bacterial | 2017 |
Bioavailability of oral antibiotics in children with short-bowel syndrome.
Topics: Administration, Oral; Anti-Bacterial Agents; Biological Availability; Cephalexin; Child; Child, Pres | 1984 |