trimethoprim has been researched along with Sarcoma, Kaposi in 9 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Sarcoma, Kaposi: A multicentric, malignant neoplastic vascular proliferation characterized by the development of bluish-red cutaneous nodules, usually on the lower extremities, most often on the toes or feet, and slowly increasing in size and number and spreading to more proximal areas. The tumors have endothelium-lined channels and vascular spaces admixed with variably sized aggregates of spindle-shaped cells, and often remain confined to the skin and subcutaneous tissue, but widespread visceral involvement may occur. Kaposi's sarcoma occurs spontaneously in Jewish and Italian males in Europe and the United States. An aggressive variant in young children is endemic in some areas of Africa. A third form occurs in about 0.04% of kidney transplant patients. There is also a high incidence in AIDS patients. (From Dorland, 27th ed & Holland et al., Cancer Medicine, 3d ed, pp2105-7) HHV-8 is the suspected cause.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The safety and efficacy of sulfamethoxazole and trimethoprim in the prevention of Pneumocystis carinii pneumonia associated with the acquired immunodeficiency syndrome (AIDS) were evaluated." | 5.06 | Safety and efficacy of sulfamethoxazole and trimethoprim chemoprophylaxis for Pneumocystis carinii pneumonia in AIDS. ( Dickinson, GM; Fischl, MA; La Voie, L, 1988) |
| "The cause of AIDS is unknown." | 1.27 | Infectious complications of the acquired immune deficiency syndrome. ( Armstrong, D; Gold, JW, 1984) |
| "A patient with Kaposi's sarcoma and the acquired immune deficiency syndrome became acutely febrile and dyspneic." | 1.27 | Pneumocystis with normal chest X-ray film and arterial oxygen tension. Early diagnosis in a patient with the acquired immune deficiency syndrome. ( Goodman, JL; Tashkin, DP, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abderrahim, E | 1 |
| Jbali, H | 1 |
| Ounissi, M | 1 |
| Hedri, H | 1 |
| Bakir, S | 1 |
| Ben Abdallah, T | 1 |
| Ben Maïz, H | 1 |
| Kheder, A | 1 |
| Gold, JW | 1 |
| Armstrong, D | 1 |
| Mitsuyasu, R | 1 |
| Groopman, J | 1 |
| Volberding, P | 1 |
| Vogt, M | 1 |
| Bettex, JD | 1 |
| Lüthy, R | 1 |
| Goodman, JL | 1 |
| Tashkin, DP | 1 |
| Masur, H | 1 |
| Frazer, IH | 1 |
| Donald, KJ | 1 |
| Fischl, MA | 1 |
| Dickinson, GM | 1 |
| La Voie, L | 1 |
| Gibson, PG | 1 |
| Bryant, DH | 1 |
| Harkness, J | 1 |
| Munro, VF | 1 |
| Penny, R | 1 |
| Cooper, DA | 1 |
1 review available for trimethoprim and Sarcoma, Kaposi
| Article | Year |
|---|---|
[Acquired immunodeficiency syndrome (AIDS). A 2-year review].
Topics: Acquired Immunodeficiency Syndrome; Antibodies, Viral; B-Lymphocytes; beta 2-Microglobulin; Biopteri | 1983 |
1 trial available for trimethoprim and Sarcoma, Kaposi
| Article | Year |
|---|---|
Safety and efficacy of sulfamethoxazole and trimethoprim chemoprophylaxis for Pneumocystis carinii pneumonia in AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Therapy, Combination; Humans; Male; Middle Aged; Pne | 1988 |
7 other studies available for trimethoprim and Sarcoma, Kaposi
| Article | Year |
|---|---|
[Association of disseminated nocardiosis and Kaposi's sarcoma after kidney transplantation].
Topics: Adult; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Drug Therapy, Combination; Humans; Imi | 2009 |
Infectious complications of the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bacterial Infections; Cytomegalovirus Infections; Drug Co | 1984 |
Cutaneous reaction to trimethoprim-sulfamethoxazole in patients with AIDS and Kaposi's sarcoma.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Drug Eruptions; Humans; Pneumonia, Pneumocyst | 1983 |
Pneumocystis with normal chest X-ray film and arterial oxygen tension. Early diagnosis in a patient with the acquired immune deficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoscopy; Humans; Male; Oxygen; Pneumonia, Pneumocyst | 1983 |
Immunotherapy and therapy of complications of AIDS.
Topics: Acquired Immunodeficiency Syndrome; Drug Combinations; Humans; Immunotherapy; Pentamidine; Pneumonia | 1984 |
First International Conference on the Acquired Immunodeficiency Syndrome.
Topics: Acquired Immunodeficiency Syndrome; Africa; Antibodies, Viral; Antiviral Agents; Deltaretrovirus; Dr | 1985 |
Pulmonary manifestations of the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Bronchoscopy; Drug Combinations; Humans; Lung Diseases; L | 1987 |