trimethoprim has been researched along with Rhabdomyolysis in 5 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Rhabdomyolysis: Necrosis or disintegration of skeletal muscle often followed by myoglobinuria.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we describe the occurrence of severe combined immunodeficiency (SCID) with megaloblastic anemia, leukopenia, atypical hemolytic uremic syndrome, and neurologic abnormalities in which hydroxocobalamin and folate therapy provided partial immune reconstitution." | 3.79 | Severe combined immunodeficiency resulting from mutations in MTHFD1. ( Baluarte, HJ; Bergqvist, AG; Ganesh, J; Heltzer, M; Keller, MD; Orange, JS; Paessler, M; Rosenblatt, DS; Watkins, D, 2013) |
| "A patient with acquired immunodeficiency syndrome (AIDS) developed rash, fever, neutropenia, and elevated liver function tests during an initial course of trimethoprim-sulfamethoxazole (TMP-SMX) therapy." | 3.67 | Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS. ( Arnold, PA; Guglielmo, BJ; Hollander, H, 1988) |
| "Hypokalaemic rhabdomyolysis is unusual, but the association between hypokalaemia and rhabdomyolysis can be overlooked if intracellular potassium leakage normalizes serum potassium by the time of presentation." | 1.34 | Hypokalaemic rhabdomyolysis. ( Kessel, B; Kishore, B; Thurlow, V, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (20.00) | 29.6817 |
| 2010's | 2 (40.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Non, LR | 1 |
| Patel, R | 1 |
| Esmaeeli, A | 1 |
| Despotovic, V | 1 |
| Keller, MD | 1 |
| Ganesh, J | 1 |
| Heltzer, M | 1 |
| Paessler, M | 1 |
| Bergqvist, AG | 1 |
| Baluarte, HJ | 1 |
| Watkins, D | 1 |
| Rosenblatt, DS | 1 |
| Orange, JS | 1 |
| Kishore, B | 1 |
| Thurlow, V | 1 |
| Kessel, B | 1 |
| Wasserheit, JN | 1 |
| Dugdale, DC | 1 |
| Agosti, JM | 1 |
| Arnold, PA | 1 |
| Guglielmo, BJ | 1 |
| Hollander, H | 1 |
5 other studies available for trimethoprim and Rhabdomyolysis
| Article | Year |
|---|---|
Typhoid Fever Complicated by Hemophagocytic Lymphohistiocytosis and Rhabdomyolysis.
Topics: Disk Diffusion Antimicrobial Tests; Drug Combinations; Drug Resistance, Bacterial; Drug Therapy, Com | 2015 |
Severe combined immunodeficiency resulting from mutations in MTHFD1.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Anemia, Megaloblastic; Bone Marrow Examination; Cardiomyopathies; | 2013 |
Hypokalaemic rhabdomyolysis.
Topics: Alcoholism; Calcium; Creatine Kinase; Female; Humans; Hypokalemia; Liver Function Tests; Magnesium; | 2007 |
Rhabdomyolysis and acute renal failure: a new presentation of acute brucellosis.
Topics: Acute Disease; Acute Kidney Injury; Adult; Brucellosis; Doxycycline; Drug Combinations; Humans; Male | 1984 |
Severe hypersensitivity reaction upon rechallenge with trimethoprim-sulfamethoxazole in a patient with AIDS.
Topics: Acquired Immunodeficiency Syndrome; Adult; Dermatitis, Exfoliative; Drug Combinations; Drug Hypersen | 1988 |