trimethoprim has been researched along with Retinal Degeneration in 1 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Retinal Degeneration: A retrogressive pathological change in the retina, focal or generalized, caused by genetic defects, inflammation, trauma, vascular disease, or aging. Degeneration affecting predominantly the macula lutea of the retina is MACULAR DEGENERATION. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p304)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Retinal degenerations are a large cluster of diseases characterized by the irreversible loss of light-sensitive photoreceptors that impairs the vision of 9." | 1.48 | A Drug-Tunable Gene Therapy for Broad-Spectrum Protection against Retinal Degeneration. ( Ash, JD; Boye, SE; Boye, SL; Imam, AA; Keuthan, CJ; Santiago, CP, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Santiago, CP | 1 |
| Keuthan, CJ | 1 |
| Boye, SL | 1 |
| Boye, SE | 1 |
| Imam, AA | 1 |
| Ash, JD | 1 |
1 other study available for trimethoprim and Retinal Degeneration
| Article | Year |
|---|---|
A Drug-Tunable Gene Therapy for Broad-Spectrum Protection against Retinal Degeneration.
Topics: Animals; Dependovirus; Gene Expression Regulation; Genetic Therapy; Humans; Leukemia Inhibitory Fact | 2018 |