Page last updated: 2024-11-05

trimethoprim and Primary Peritonitis

trimethoprim has been researched along with Primary Peritonitis in 14 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Research Excerpts

ExcerptRelevanceReference
"The extensive use of invasive procedures and of long-term norfloxacin prophylaxis in the management of cirrhotic patients may have influenced the epidemiology of bacterial infections in cirrhosis."7.71Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. ( Arroyo, V; Colmenero, J; Fernández, J; Gómez, J; Navasa, M; Rodés, J; Vila, J, 2002)
"Trimethoprim-sulfadiazine and gentamicin sulfate decreased early mortality in an established model of fibrinous peritonitis in the rat."7.67Efficacies of trimethoprim-sulfadiazine and gentamicin sulfate in the treatment of fibrinous peritonitis in rats. ( Benson, CE; Emms, SG, 1987)
" The dosage yielded too high plasma trimethoprim concentrations, while sulfamethoxazole dialysate concentrations were too low."5.27Pharmacokinetics of cefradine, sulfamethoxazole and trimethoprim and their metabolites in a patient with peritonitis undergoing continuous ambulatory peritoneal dialysis. ( Berden, JH; Hekster, YA; Martea, M; Voets, AJ; Vree, TB, 1987)
"Vancomycin was found to be appropriate in particular because of the resistance characteristics of bacterial isolates."5.27[Treatment of peritonitis during continuous ambulatory peritoneal dialysis (CAPD) with co-trimoxazole, cefazolin or vancomycin]. ( Binswanger, U; König, U; Müller, U, 1987)
"The extensive use of invasive procedures and of long-term norfloxacin prophylaxis in the management of cirrhotic patients may have influenced the epidemiology of bacterial infections in cirrhosis."3.71Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. ( Arroyo, V; Colmenero, J; Fernández, J; Gómez, J; Navasa, M; Rodés, J; Vila, J, 2002)
"Trimethoprim-sulfadiazine and gentamicin sulfate decreased early mortality in an established model of fibrinous peritonitis in the rat."3.67Efficacies of trimethoprim-sulfadiazine and gentamicin sulfate in the treatment of fibrinous peritonitis in rats. ( Benson, CE; Emms, SG, 1987)
"It is concluded that initial treatment of CAPD peritonitis with co-trimoxazole is justified by the high proportion of sensitive germs and that it represents a safe, efficient and inexpensive treatment."1.27Treatment of peritonitis in continuous ambulatory peritoneal dialysis patients with co-trimoxazole. ( Favre, H; Glasson, P, 1984)
" The dosage yielded too high plasma trimethoprim concentrations, while sulfamethoxazole dialysate concentrations were too low."1.27Pharmacokinetics of cefradine, sulfamethoxazole and trimethoprim and their metabolites in a patient with peritonitis undergoing continuous ambulatory peritoneal dialysis. ( Berden, JH; Hekster, YA; Martea, M; Voets, AJ; Vree, TB, 1987)
"Vancomycin was found to be appropriate in particular because of the resistance characteristics of bacterial isolates."1.27[Treatment of peritonitis during continuous ambulatory peritoneal dialysis (CAPD) with co-trimoxazole, cefazolin or vancomycin]. ( Binswanger, U; König, U; Müller, U, 1987)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-199011 (78.57)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Glasson, P1
Favre, H1
Winslow, DL1
Steele, ML1
de Fremont, JF1
Schmit, JL1
Thomas, D1
Coevoet, B1
Eb, F1
Laurence, G1
Orfila, J1
Fournier, A1
Singlas, E1
Colin, JN1
Rottembourg, J1
Meessen, JP1
de Martin, A1
Legrain, M1
Simon, P1
Tilgner, SL1
Anstey, SI1
Fernández, J1
Navasa, M1
Gómez, J1
Colmenero, J1
Vila, J1
Arroyo, V1
Rodés, J1
Tally, FP1
Gorbach, SL1
Goris, RJ2
van Bebber, IP2
Mollen, RM2
Koopman, JP2
Morris, AJ1
Henderson, GK1
Bremner, DA1
Collins, JF1
Martea, M1
Hekster, YA1
Vree, TB1
Voets, AJ1
Berden, JH1
König, U1
Müller, U1
Binswanger, U1
Höllwarth, M1
Graf, D1
Kurz, R1
Sauer, H1
Emms, SG1
Benson, CE1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Patterns of Antibiotic Resistant Bacterial Infections in Liver Intensive Care Unit[NCT03855709]200 participants (Anticipated)Observational2019-05-31Not yet recruiting
Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis in Patients With Acute Variceal Bleeding[NCT00838864]Phase 479 participants (Actual)Interventional2009-03-31Completed
Comparison of Daily Norfloxacin Versus Weekly Ciprofloxacin for the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients[NCT01542801]Phase 4124 participants (Actual)Interventional2011-08-31Completed
Rifaximin Versus Norfloxacin in the Primary Prophylaxis of Spontaneous Bacterial Peritonitis[NCT04159870]Phase 3322 participants (Anticipated)Interventional2019-11-05Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

1 review available for trimethoprim and Primary Peritonitis

ArticleYear
Antibiotics in surgery.
    Advances in surgery, 1975, Volume: 9

    Topics: Anti-Bacterial Agents; Bacterial Infections; Biliary Tract Diseases; Burns; Catheterization; Cephalo

1975

Trials

1 trial available for trimethoprim and Primary Peritonitis

ArticleYear
[Antibiotic treatment of perforated appendicitis in childhood--a prospective study].
    Zeitschrift fur Kinderchirurgie : organ der Deutschen, der Schweizerischen und der Osterreichischen Gesellschaft fur Kinderchirurgie = Surgery in infancy and childhood, 1986, Volume: 41, Issue:1

    Topics: Anti-Bacterial Agents; Appendectomy; Appendicitis; Child; Clinical Trials as Topic; Drug Combination

1986

Other Studies

12 other studies available for trimethoprim and Primary Peritonitis

ArticleYear
Treatment of peritonitis in continuous ambulatory peritoneal dialysis patients with co-trimoxazole.
    Nephron, 1984, Volume: 36, Issue:1

    Topics: Adult; Aged; Anti-Infective Agents, Urinary; Bacterial Infections; Drug Combinations; Female; Humans

1984
Listeria bacteremia and peritonitis associated with a peritoneovenous shunt: successful treatment with sulfamethoxazole and trimethoprim.
    The Journal of infectious diseases, 1984, Volume: 149, Issue:5

    Topics: Aged; Humans; Listeriosis; Male; Peritoneovenous Shunt; Peritonitis; Postoperative Complications; Se

1984
[Treatment of peritonitis in continuous ambulatory peritoneal dialysis ].
    Pathologie-biologie, 1982, Volume: 30, Issue:6 Pt 2

    Topics: Adult; Aged; Amphotericin B; Anti-Bacterial Agents; Candidiasis; Drug Combinations; Humans; Kidney F

1982
Pharmacokinetics of sulfamethoxazole--trimethoprim combination during chronic peritoneal dialysis: effect of peritonitis.
    European journal of clinical pharmacology, 1982, Volume: 21, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Aged; Drug Combinations; Female; Humans; Kidney Failure, Ch

1982
Nocardial peritonitis in a cat.
    Australian veterinary journal, 1996, Volume: 74, Issue:6

    Topics: Animals; Anti-Infective Agents; Cat Diseases; Cats; Combined Modality Therapy; Drainage; Fluid Thera

1996
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Does selective decontamination of the gastrointestinal tract prevent multiple organ failure? An experimental study.
    Archives of surgery (Chicago, Ill. : 1960), 1991, Volume: 126, Issue:5

    Topics: Animals; Digestive System; Enterobacteriaceae; Enterobacteriaceae Infections; Feces; Lymph Nodes; Ma

1991
Decontamination of the gastrointestinal tract and prevention of multiple organ failure. An experimental study.
    Progress in clinical and biological research, 1989, Volume: 308

    Topics: Animals; Digestive System; Disinfection; Enterobacteriaceae; Male; Multiple Organ Failure; Peritonit

1989
Relapsing peritonitis in a patient undergoing continuous ambulatory peritoneal dialysis due to Corynebacterium aquaticum.
    The Journal of infection, 1986, Volume: 13, Issue:2

    Topics: Adult; Anti-Bacterial Agents; Corynebacterium; Corynebacterium Infections; Diabetic Nephropathies; D

1986
Pharmacokinetics of cefradine, sulfamethoxazole and trimethoprim and their metabolites in a patient with peritonitis undergoing continuous ambulatory peritoneal dialysis.
    Pharmaceutisch weekblad. Scientific edition, 1987, Apr-24, Volume: 9, Issue:2

    Topics: Anti-Infective Agents, Urinary; Cephalosporins; Cephradine; Drug Combinations; Half-Life; Humans; Ki

1987
[Treatment of peritonitis during continuous ambulatory peritoneal dialysis (CAPD) with co-trimoxazole, cefazolin or vancomycin].
    Klinische Wochenschrift, 1987, Jul-15, Volume: 65, Issue:12

    Topics: Anti-Bacterial Agents; Anti-Infective Agents; Aspergillus; Bacteria; Candida; Cefazolin; Drug Combin

1987
Efficacies of trimethoprim-sulfadiazine and gentamicin sulfate in the treatment of fibrinous peritonitis in rats.
    American journal of veterinary research, 1987, Volume: 48, Issue:4

    Topics: Animals; Disease Models, Animal; Drug Combinations; Gentamicins; Male; Peritonitis; Rats; Rats, Inbr

1987