trimethoprim has been researched along with Porphyrias in 1 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Porphyrias: A diverse group of metabolic diseases characterized by errors in the biosynthetic pathway of HEME in the LIVER, the BONE MARROW, or both. They are classified by the deficiency of specific enzymes, the tissue site of enzyme defect, or the clinical features that include neurological (acute) or cutaneous (skin lesions). Porphyrias can be hereditary or acquired as a result of toxicity to the hepatic or erythropoietic marrow tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The porphyrias are a group of diseases which may be complicated by acute neurological crises having serious morbidity and a high rate of mortality." | 1.27 | Otolaryngologic complications of acute porphyria. ( Hockman, M; Kallenbach, J; Lewis, M; Zaltzman, M; Zwi, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Lewis, M | 1 |
| Kallenbach, J | 1 |
| Hockman, M | 1 |
| Zaltzman, M | 1 |
| Zwi, S | 1 |
1 other study available for trimethoprim and Porphyrias
| Article | Year |
|---|---|
Otolaryngologic complications of acute porphyria.
Topics: Acute Disease; Adult; Drug Combinations; Female; Humans; Pneumonia, Aspiration; Porphyrias; Quadripl | 1983 |