trimethoprim has been researched along with Pneumocystis Infections in 14 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Pneumocystis Infections: Infections with species in the genus PNEUMOCYSTIS, a fungus causing interstitial plasma cell pneumonia (PNEUMONIA, PNEUMOCYSTIS) and other infections in humans and other MAMMALS. Immunocompromised patients, especially those with AIDS, are particularly susceptible to these infections. Extrapulmonary sites are rare but seen occasionally.
| Excerpt | Relevance | Reference |
|---|---|---|
| " The panel members discussed the use of valacyclovir (Valtrex) to provide prophylaxis for herpes zoster, trimethoprim/sulfamethoxazole for Pneumocystis, and acyclovir (Zovirax) for varicella zoster." | 3.70 | Infectious complications of pentostatin therapy. ( Cabanillas, F; Dang, N; Drapkin, R; Foss, F; O'Brien, S; Vose, JM, 2000) |
| "We report a case of P carinii infection presenting as bilateral aural polyps, otitis media and mastoiditis in human immunodeficiency (HIV)-positive patient with no history of prior or concomitant P carinii infection." | 2.41 | Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient. ( Elmahallawy, M; Horsfield, C; Praveen, CV; Terry, RM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 8 (57.14) | 18.2507 |
| 2000's | 5 (35.71) | 29.6817 |
| 2010's | 1 (7.14) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gangjee, A | 1 |
| Shi, J | 1 |
| Queener, SF | 1 |
| Barrows, LR | 1 |
| Kisliuk, RL | 1 |
| Vinker-Shuster, M | 1 |
| Stepensky, P | 1 |
| Temper, V | 1 |
| Shayovitz, V | 1 |
| Masarwa, R | 1 |
| Averbuch, D | 1 |
| Ma, L | 1 |
| Jia, Q | 1 |
| Kovacs, JA | 1 |
| Rodriguez, M | 1 |
| Fishman, JA | 1 |
| Mehlhorn, H | 1 |
| Dankert, W | 1 |
| Hartman, PG | 1 |
| Then, RL | 1 |
| Hughes, WT | 1 |
| Killmar, JT | 1 |
| Oz, HS | 1 |
| Patey, O | 1 |
| Salvanet, A | 1 |
| Serrhini, A | 1 |
| Lafaix, C | 1 |
| Brun-Pascaud, M | 1 |
| Chau, F | 1 |
| Garry, L | 1 |
| Jacobus, D | 1 |
| Derouin, F | 1 |
| Girard, PM | 1 |
| Ruggli, GM | 1 |
| Weber, R | 1 |
| Messmer, EP | 1 |
| Font, RL | 1 |
| Moll, C | 1 |
| Bernauer, W | 1 |
| Machado, CM | 1 |
| Macedo, MC | 1 |
| Medeiros, RS | 1 |
| Massumoto, C | 1 |
| Silva, AC | 1 |
| Castelli, JB | 1 |
| Silva, RL | 1 |
| Ostronoff, M | 1 |
| Dulley, FL | 1 |
| Patel, SK | 1 |
| Philpott, JM | 1 |
| McPartlin, DW | 1 |
| Vasconcelles, MJ | 1 |
| Bernardo, MV | 1 |
| King, C | 1 |
| Weller, EA | 1 |
| Antin, JH | 1 |
| Vose, JM | 1 |
| Cabanillas, F | 1 |
| O'Brien, S | 1 |
| Dang, N | 1 |
| Drapkin, R | 1 |
| Foss, F | 1 |
| Praveen, CV | 1 |
| Terry, RM | 1 |
| Elmahallawy, M | 1 |
| Horsfield, C | 1 |
3 reviews available for trimethoprim and Pneumocystis Infections
| Article | Year |
|---|---|
Prevention of infection due to Pneumocystis spp. in human immunodeficiency virus-negative immunocompromised patients.
Topics: AIDS-Related Opportunistic Infections; Antifungal Agents; Bone Marrow Transplantation; Humans; Immun | 2004 |
An unusual case of Pneumocystis carinii presenting as an aural mass.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Dapsone; Drug Therapy, Combinat | 1999 |
Pneumocystis carinii infection in bilateral aural polyps in a human immunodeficiency virus-positive patient.
Topics: Adult; AIDS-Related Opportunistic Infections; Antifungal Agents; Dapsone; Ear Neoplasms; Ear, Middle | 2002 |
2 trials available for trimethoprim and Pneumocystis Infections
| Article | Year |
|---|---|
Gram-negative Bacteremia in Children With Hematologic Malignancies and Following Hematopoietic Stem Cell Transplantation: Epidemiology, Resistance, and Outcome.
Topics: Adolescent; Allografts; Bacteremia; Child; Child, Preschool; Drug Combinations; Drug Resistance, Bac | 2019 |
Aerosolized pentamidine as pneumocystis prophylaxis after bone marrow transplantation is inferior to other regimens and is associated with decreased survival and an increased risk of other infections.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Antifungal Agents; Bone Ma | 2000 |
9 other studies available for trimethoprim and Pneumocystis Infections
| Article | Year |
|---|---|
Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents.
Topics: Animals; Antineoplastic Agents; Disease Models, Animal; Folic Acid Antagonists; Fungal Proteins; Hum | 1993 |
Development of a yeast assay for rapid screening of inhibitors of human-derived Pneumocystis carinii dihydrofolate reductase.
Topics: Animals; Drug Evaluation, Preclinical; Folic Acid Antagonists; Humans; Pneumocystis; Pneumocystis In | 2002 |
A pilot study on the efficacy of epiroprim against developmental stages of Toxoplasma gondii and Pneumocystis carinii in animal models.
Topics: Animals; Anti-Bacterial Agents; Anti-Infective Agents; Dapsone; Drug Therapy, Combination; Female; F | 1995 |
Relative potency of 10 drugs with anti-Pneumocystis carinii activity in an animal model.
Topics: Animals; Anti-Infective Agents; Atovaquone; Azithromycin; Clarithromycin; Clindamycin; Clinical Tria | 1994 |
Pneumocystis carinii choroidopathy in AIDS patients.
Topics: Adult; AIDS-Related Opportunistic Infections; Angiography; Choroiditis; Humans; Male; Pneumocystis I | 1993 |
Combination of PS-15, epiroprim, or pyrimethamine with dapsone in prophylaxis of Toxoplasma gondii and Pneumocystis carinii dual infection in a rat model.
Topics: Animals; Anti-Bacterial Agents; Antiprotozoal Agents; Dapsone; Drug Therapy, Combination; Folic Acid | 1996 |
Pneumocystis carinii infection of the conjunctiva in a patient with acquired immune deficiency syndrome.
Topics: Adult; AIDS-Related Opportunistic Infections; Anti-Infective Agents; Conjunctiva; Conjunctival Disea | 1997 |
Primary Pneumocystis carinii prophylaxis with aerosolized pentamidine after bone marrow transplantation.
Topics: Aerosols; Bone Marrow Transplantation; Female; Humans; Immunocompromised Host; Male; Pentamidine; Pn | 1998 |
Infectious complications of pentostatin therapy.
Topics: Acyclovir; Anti-Infective Agents; Anti-Infective Agents, Urinary; Antibiotics, Antineoplastic; Antib | 2000 |