trimethoprim has been researched along with Plague in 3 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Plague: An acute infectious disease caused by YERSINIA PESTIS that affects humans, wild rodents, and their ectoparasites. This condition persists due to its firm entrenchment in sylvatic rodent-flea ecosystems throughout the world. Bubonic plague is the most common form.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of exogenic addition of purines and pyrimidines on trimethoprim sensitivity was studied in 134 vaccinal and virulent strains of the plague causative agent isolated at various periods in 12 natural plague foci." | 7.67 | [Study of trimethoprim sensitivity in strains of Yersinia pestis isolated from various natural foci of plague]. ( Kravchenko, AN; Mishan'kin, BN, 1989) |
| "The effect of exogenic addition of purines and pyrimidines on trimethoprim sensitivity was studied in 134 vaccinal and virulent strains of the plague causative agent isolated at various periods in 12 natural plague foci." | 3.67 | [Study of trimethoprim sensitivity in strains of Yersinia pestis isolated from various natural foci of plague]. ( Kravchenko, AN; Mishan'kin, BN, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kravchenko, AN | 1 |
| Mishan'kin, BN | 1 |
| Butler, T | 1 |
| Bell, WR | 1 |
| Arnold, K | 1 |
3 other studies available for trimethoprim and Plague
| Article | Year |
|---|---|
[Study of trimethoprim sensitivity in strains of Yersinia pestis isolated from various natural foci of plague].
Topics: Drug Resistance, Microbial; Microbial Sensitivity Tests; Plague; Thymidine; Thymine; Trimethoprim; U | 1989 |
Letter: Co-trimoxazole in bubonic plague.
Topics: Adolescent; Adult; Child; Female; Humans; Male; Middle Aged; Plague; Sulfamethoxazole; Time Factors; | 1973 |
Yersinia pestis infection in Vietnam. I. Clinical and hematologic aspects.
Topics: Adolescent; Adult; Aged; Antibodies, Bacterial; Blood; Blood Cell Count; Child; Child, Preschool; Ch | 1974 |