trimethoprim has been researched along with Pancytopenia in 16 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Pancytopenia: Deficiency of all three cell elements of the blood, erythrocytes, leukocytes and platelets.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The authors report a case of fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy in a patient with folic acid deficiency." | 7.66 | [Fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy (author's transl)]. ( Bald, P; Barale, F; Boillot, A; Daoudal, P; Rozenbaum, A; Stimmesse, B, 1979) |
| "In 8 of 18 homosexual men with the acquired immunodeficiency syndrome (AIDS) and Pneumocystis carinii pneumonia (PCP) treated with intravenous co-trimoxazole (trimethoprim-sulphamethoxazole) apparent drug-related complications developed during the course of acute therapy." | 3.66 | Complications of co-trimoxazole in treatment of AIDS-associated Pneumocystis carinii pneumonia in homosexual men. ( Abrams, DI; Ammann, AJ; Golden, JA; Jaffe, HS; Lewis, BJ, 1983) |
| "The authors report a case of fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy in a patient with folic acid deficiency." | 3.66 | [Fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy (author's transl)]. ( Bald, P; Barale, F; Boillot, A; Daoudal, P; Rozenbaum, A; Stimmesse, B, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (87.50) | 18.7374 |
| 1990's | 1 (6.25) | 18.2507 |
| 2000's | 1 (6.25) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sathi, N | 1 |
| Dawson, J | 1 |
| Jaffe, HS | 1 |
| Abrams, DI | 1 |
| Ammann, AJ | 1 |
| Lewis, BJ | 1 |
| Golden, JA | 1 |
| Le Blanc, C | 1 |
| Bricard, H | 1 |
| Levrot, A | 1 |
| Leroy, G | 1 |
| Trovero, C | 1 |
| Quesnel, J | 1 |
| Chanu, B | 1 |
| Kernbaum, S | 1 |
| Uzzan, B | 1 |
| Faille, A | 1 |
| Blasetti, A | 1 |
| Rouffy, J | 1 |
| Stimmesse, B | 1 |
| Daoudal, P | 1 |
| Boillot, A | 1 |
| Bald, P | 1 |
| Rozenbaum, A | 1 |
| Barale, F | 1 |
| Blackwell, EA | 1 |
| Hawson, GA | 1 |
| Leer, J | 1 |
| Bain, B | 1 |
| Casthelat, J | 1 |
| Jaouen, E | 1 |
| Deroide, JP | 1 |
| Verbov, JL | 2 |
| McKinsey, DS | 1 |
| Durfee, D | 1 |
| Kurtin, PJ | 1 |
| Jeurissen, ME | 1 |
| Boerbooms, AM | 1 |
| van de Putte, LB | 1 |
| Thevenet, JP | 1 |
| Ristori, JM | 1 |
| Cure, H | 1 |
| Mizony, MH | 1 |
| Bussiere, JL | 1 |
| Ng, HW | 1 |
| Macfarlane, AW | 1 |
| Graham, RM | 1 |
| Maricic, M | 1 |
| Davis, M | 1 |
| Gall, EP | 1 |
| Thomas, DR | 1 |
| Dover, JS | 1 |
| Camp, RD | 1 |
| Uppenkamp, M | 1 |
| Hoensch, H | 1 |
| König, E | 1 |
| Przybilla, CG | 1 |
| Ohnhaus, EE | 1 |
| Gordon-Smith, EC | 1 |
16 other studies available for trimethoprim and Pancytopenia
| Article | Year |
|---|---|
Methotrexate-induced pancytopenia associated with co-prescription of penicillin and trimethoprim.
Topics: Anti-Infective Agents; Antirheumatic Agents; Arthritis, Rheumatoid; Drug Prescriptions; Humans; Medi | 2007 |
Complications of co-trimoxazole in treatment of AIDS-associated Pneumocystis carinii pneumonia in homosexual men.
Topics: Acquired Immunodeficiency Syndrome; Adult; Drug Combinations; Fever; Headache; Homosexuality; Humans | 1983 |
[Pancytopenia associated with sulfamethoxazole-trimethoprime I.V. therapy (author's transl)].
Topics: Aged; Drug Combinations; Humans; Injections, Intravenous; Male; Pancytopenia; Sulfamethoxazole; Trim | 1981 |
[Bone marrow aplasia induced by sulfamethoxazole-trimethoprim. Evidence of an allergic mechanism].
Topics: Drug Hypersensitivity; Female; Humans; Middle Aged; Pancytopenia; Sulfamethoxazole; Trimethoprim | 1981 |
[Fatal pancytopenia associated with sulfamethoxazole-trimethoprim therapy (author's transl)].
Topics: Drug Combinations; Folic Acid Deficiency; Humans; Male; Middle Aged; Pancytopenia; Sulfamethoxazole; | 1979 |
Acute pancytopenia due to megaloblastic arrest in association with co-trimoxazole.
Topics: Acute Disease; Aged; Anemia, Megaloblastic; Bone Marrow Diseases; Drug Combinations; Erythrocytes, A | 1978 |
[Pancytopenia resulting from treatment with sulfamethoxazole-trimethoprim].
Topics: Aged; Drug Combinations; Female; Humans; Pancytopenia; Sulfamethoxazole; Trimethoprim | 1978 |
Methotrexate and trimethoprim-sulphamethoxazole.
Topics: Aged; Drug Interactions; Female; Humans; Methotrexate; Pancytopenia; Skin Ulcer; Trimethoprim | 1991 |
Megaloblastic pancytopenia associated with dapsone and trimethoprim treatment of Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome.
Topics: Acquired Immunodeficiency Syndrome; Adult; Dapsone; Drug Therapy, Combination; Humans; Male; Pancyto | 1989 |
Pancytopenia and methotrexate with trimethoprim-sulfamethoxazole.
Topics: Aged; Aged, 80 and over; Drug Combinations; Drug Interactions; Female; Humans; Methotrexate; Pancyto | 1989 |
[Pancytopenia during treatment of rheumatoid arthritis with methotrexate after administration of trimethoprim-sulfamethoxazole].
Topics: Anti-Infective Agents; Arthritis, Rheumatoid; Drug Combinations; Drug Synergism; Drug Therapy, Combi | 1987 |
Near fatal drug interactions with methotrexate given for psoriasis.
Topics: Aged; Aged, 80 and over; Drug Interactions; Female; Humans; Methotrexate; Naproxen; Necrosis; Pancyt | 1987 |
Megaloblastic pancytopenia in a patient receiving concurrent methotrexate and trimethoprim-sulfamethoxazole treatment.
Topics: Abscess; Breast Diseases; Cough; Drug Combinations; Erythrocytes; Erythrocytes, Abnormal; Female; Fo | 1986 |
Pancytopenia induced by the interaction between methotrexate and trimethoprim-sulfamethoxazole.
Topics: Aged; Aged, 80 and over; Anti-Infective Agents; Drug Combinations; Drug Therapy, Combination; Female | 1987 |
[Pancytopenia and Salmonella infantis infection].
Topics: Anti-Infective Agents; Drug Combinations; Female; Gastroenteritis; Humans; Middle Aged; Pancytopenia | 1986 |
Treatment of aplastic anemias.
Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Antifungal Agents; Antilymphocyte Serum; Bone Marrow | 1985 |