trimethoprim has been researched along with Otosclerosis in 2 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Otosclerosis: Formation of spongy bone in the labyrinth capsule which can progress toward the STAPES (stapedial fixation) or anteriorly toward the COCHLEA leading to conductive, sensorineural, or mixed HEARING LOSS. Several genes are associated with familial otosclerosis with varied clinical signs.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jacob, M | 2 |
| Causse, J | 2 |
| Gaudy, D | 2 |
| Duru, C | 2 |
| Causse, JB | 2 |
| Puech, A | 2 |
2 other studies available for trimethoprim and Otosclerosis
| Article | Year |
|---|---|
[Diffusion of the drug combination sulfamethoxazole-trimethoprim. Microdetermination in the perilymph, blood and urine of subjects with otosclerosis].
Topics: Adult; Aged; Drug Combinations; Female; Humans; Kinetics; Labyrinthine Fluids; Male; Middle Aged; Ot | 1982 |
[Antibacterial therapy in surgery of the inner and middle ear. A study of co-trimoxazole penetration into the perilymph (author's transl)].
Topics: Adult; Aged; Chromatography, Thin Layer; Drug Combinations; Ear, Inner; Ear, Middle; Female; Humans; | 1982 |