trimethoprim has been researched along with Otitis Media with Effusion in 17 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "78 pediatric patients affected by acute otitis media were selected and randomized into two balanced groups of treatment: brodimoprim, at the dosage of 200 mg once-a-day on the first day and of 100 mg once-a-day on the following days, and cefaclor at a dosage of 40 mg/Kg/day in three doses." | 9.07 | Efficacy and tolerability of brodimoprim in bacterial otitis media in children. Controlled study versus cefaclor. ( Bergamini, G; Cantini, L; Dallari, S; Galetti, G; Ghidini, A; Martini, A; Mazzoli, M; Monici Preti, PA, 1993) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 7.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "78 pediatric patients affected by acute otitis media were selected and randomized into two balanced groups of treatment: brodimoprim, at the dosage of 200 mg once-a-day on the first day and of 100 mg once-a-day on the following days, and cefaclor at a dosage of 40 mg/Kg/day in three doses." | 5.07 | Efficacy and tolerability of brodimoprim in bacterial otitis media in children. Controlled study versus cefaclor. ( Bergamini, G; Cantini, L; Dallari, S; Galetti, G; Ghidini, A; Martini, A; Mazzoli, M; Monici Preti, PA, 1993) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 3.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "Otitis media with effusion is the most common cause of hearing loss in children." | 2.65 | Antimicrobial therapy of chronic otitis media with effusion. ( Healy, GB, 1984) |
| "Acute otitis media is commonly caused by pneumococcus and Hemophilus influenzae." | 1.27 | Developments in diagnosing and treating otitis media. ( Eichenwald, H, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 12 (70.59) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schreiner, A | 1 |
| Marks, NJ | 2 |
| Mills, RP | 3 |
| Shaheen, OH | 2 |
| Healy, GB | 1 |
| Kohonen, A | 1 |
| Palmgren, O | 1 |
| Renkonen, OV | 1 |
| Klimek, JJ | 2 |
| Bates, TR | 1 |
| Nightingale, C | 1 |
| Lehmann, WB | 2 |
| Ziemniak, JA | 1 |
| Quintiliani, R | 2 |
| Krause, PJ | 1 |
| Owens, NJ | 1 |
| Nightingale, CH | 1 |
| Roark, R | 1 |
| Petrofski, J | 1 |
| Berson, E | 1 |
| Berman, S | 2 |
| Le, CT | 1 |
| Lindgren, BR | 1 |
| Daly, KA | 1 |
| Giebink, GS | 1 |
| Scaglione, F | 1 |
| Cogo, R | 1 |
| Pintucci, JP | 1 |
| Demartini, G | 1 |
| Dugnani, S | 1 |
| Maccarinelli, G | 1 |
| Fraschini, F | 1 |
| Galetti, G | 1 |
| Martini, A | 1 |
| Bergamini, G | 1 |
| Dallari, S | 1 |
| Ghidini, A | 1 |
| Mazzoli, M | 1 |
| Cantini, L | 1 |
| Monici Preti, PA | 1 |
| Barnett, ED | 1 |
| Teele, DW | 1 |
| Klein, JO | 1 |
| Cabral, HJ | 1 |
| Kharasch, SJ | 1 |
| Pestalozza, G | 1 |
| Romagnoli, M | 1 |
| Tessitore, E | 1 |
| Formica, U | 1 |
| Grose, K | 1 |
| Zerbe, GO | 1 |
| Eichenwald, H | 1 |
| Uttley, AH | 1 |
| McIntyre, MF | 1 |
| Puhakka, H | 1 |
| Haapaniemi, J | 1 |
| Tuohimaa, P | 1 |
| Ruuskanen, O | 1 |
| Eskola, J | 1 |
10 trials available for trimethoprim and Otitis Media with Effusion
| Article | Year |
|---|---|
Cotrimoxazole in the treatment of serous otitis. A follow-up report.
Topics: Child; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Follow-Up Studies; Humans; Mul | 1983 |
Antimicrobial therapy of chronic otitis media with effusion.
Topics: Anti-Bacterial Agents; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Ear Canal; Ear | 1984 |
A controlled trial of cotrimoxazole therapy in serous otitis media.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; H | 1981 |
Practice variations among pediatricians and family physicians in the management of otitis media.
Topics: Child, Preschool; Colorado; Decision Making; Family Practice; Humans; Infant; Male; Middle Ear Venti | 1995 |
Treatment evaluation in otitis media research.
Topics: Child; Child, Preschool; Combined Modality Therapy; Data Interpretation, Statistical; Humans; Infant | 1994 |
Brodimoprim concentrations in bronchial mucosa, bronchial secretions and middle ear effusions.
Topics: Administration, Oral; Adult; Aged; Bronchi; Bronchitis; Chronic Disease; Exudates and Transudates; F | 1993 |
Efficacy and tolerability of brodimoprim in bacterial otitis media in children. Controlled study versus cefaclor.
Topics: Acute Disease; Bacterial Infections; Cefaclor; Child; Child, Preschool; Female; Humans; Male; Otitis | 1993 |
Comparison of ceftriaxone and trimethoprim-sulfamethoxazole for acute otitis media. Greater Boston Otitis Media Study Group.
Topics: Anti-Bacterial Agents; Ceftriaxone; Cephalosporins; Child, Preschool; Drug Therapy, Combination; Fem | 1997 |
Medical management of chronic middle-ear effusion. Results of a clinical trial of prednisone combined with sulfamethoxazole and trimethoprim.
Topics: Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Double-Blind Method; Drug Combin | 1987 |
Peroral prednisolone in the treatment of middle-ear effusion in children: a double-blind study.
Topics: Administration, Oral; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug C | 1985 |
7 other studies available for trimethoprim and Otitis Media with Effusion
| Article | Year |
|---|---|
Pathogenicity of Branhamella catarrhalis.
Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Combinations; Drug Resistance, Microbial; Erythrom | 1984 |
Penetration of trimethoprim--sulfadiazine into middle ear fluid in secretory otitis media.
Topics: Adolescent; Child; Child, Preschool; Ear, Middle; Female; Humans; Infant; Male; Otitis Media; Otitis | 1983 |
Penetration characteristics of trimethoprim-sulfamethoxazole in middle ear fluid of patients with chronic serous otitis media.
Topics: Child; Chronic Disease; Exudates and Transudates; Humans; Otitis Media; Otitis Media with Effusion; | 1980 |
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea | 1982 |
[Diagnostic and therapeutic protocol in otitis media in the 1st year of life].
Topics: Acute Disease; Age Factors; Amoxicillin; Drug Combinations; Humans; Infant; Infant, Newborn; Middle | 1988 |
Developments in diagnosing and treating otitis media.
Topics: Anti-Bacterial Agents; Bacterial Vaccines; Child; Child, Preschool; Drug Combinations; Hearing Disor | 1985 |
A bacteriological study of the middle ear and upper respiratory tract in children with chronic secretory otitis media.
Topics: Adenoidectomy; Ampicillin; Child; Child, Preschool; Ear, External; Ear, Middle; Female; Haemophilus | 1985 |