Page last updated: 2024-11-05

trimethoprim and Neutropenia

trimethoprim has been researched along with Neutropenia in 49 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Neutropenia: A decrease in the number of NEUTROPHILS found in the blood.

Research Excerpts

ExcerptRelevanceReference
"A total of 63 neutropenic patients receiving cytotoxic therapy for acute leukemia were randomly allocated to receive norfloxacin (400 mg every 12 hours) or cotrimoxazole (160/800 mg every 12 hours) to prevent bacterial infection."9.06Comparison of norfloxacin with cotrimoxazole for infection prophylaxis in acute leukemia. The trade-off for reduced gram-negative sepsis. ( Bow, EJ; Louie, TJ; Rayner, E, 1988)
"Oral trimethoprim-sulfamethoxazole (Bactrim) plus erythromycin (TMZ-E) was tested versus placebo (P) as prophylaxis for bacterial infection in a randomized, double-blind trial in adult cancer patients receiving cytotoxic chemotherapy expected to result in significant neutropenia."9.05Prophylaxis of fever and infection in adult cancer patients. A placebo-controlled trial of oral trimethoprim-sulfamethoxazole plus erythromycin. ( Carr, DJ; Johnson, A; Kramer, BS; Pizzo, PA; Rand, KH; Robichaud, KJ; Yucha, JB, 1984)
"The efficacy of orally administered trimethoprim/sulfamethoxazole for infection prevention following induction chemotherapy was evaluated in 43 patients with acute leukemia."9.05Oral trimethoprim/sulfamethoxazole in attempt to prevent infection after induction chemotherapy for acute leukemia. ( Arlin, Z; Armstrong, D; Clarkson, B; Gee, T; Henry, SA; Kempin, S, 1984)
"We conducted a prospective, controlled, randomized trial of oral trimethoprim-sulfamethoxazole treatment in patients with acute leukemia receiving consolidation chemotherapy."9.05Prophylactic trimethoprim-sulfamethoxazole during consolidation chemotherapy for acute leukemia: a controlled trial. ( Armstrong, D; Fialk, MA; Lange, M; Singer, C; Szatrowski, TH; Weiser, B, 1981)
"The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days."7.67Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984)
"6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine."7.67Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986)
"In patients with AIDS, oral therapy with trimethoprim-sulfamethoxazole and with trimethoprim-dapsone are equally effective for mild-to-moderate first episodes of P."6.67Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone. ( Benowitz, N; Hopewell, PC; Lee, B; Leoung, G; Medina, I; Mills, J; Modin, G; Wofsy, CB, 1990)
"A total of 63 neutropenic patients receiving cytotoxic therapy for acute leukemia were randomly allocated to receive norfloxacin (400 mg every 12 hours) or cotrimoxazole (160/800 mg every 12 hours) to prevent bacterial infection."5.06Comparison of norfloxacin with cotrimoxazole for infection prophylaxis in acute leukemia. The trade-off for reduced gram-negative sepsis. ( Bow, EJ; Louie, TJ; Rayner, E, 1988)
"Eighty-four cancer patients at risk of infection because of neutropenia were randomized to receive nalidixic acid as an alternative to trimethoprim-sulfamethoxazole (TMP-SMX) for infection prophylaxis."5.06Selective gut decontamination with nalidixic acid or trimethoprim-sulfamethoxazole for infection prophylaxis in neutropenic cancer patients: relationship of efficacy to antimicrobial spectrum and timing of administration. ( Bow, EJ; Louie, TJ; Rayner, E; Scott, BA, 1987)
"43 patients undergoing treatment for acute leukaemia were randomised to receive either co-trimoxazole alone or co-trimoxazole with framycetin and colistin as antibacterial prophylaxis during periods of neutropenia."5.05Co-trimoxazole alone for prevention of bacterial infection in patients with acute leukaemia. ( Catovsky, D; Darrell, J; Donnelly, P; Galton, DA; Goldman, JM; Johnson, SA; Starke, ID, 1982)
"Of 545 patients expected to develop prolonged neutropenia and randomized to received trimethoprim-sulfamethoxazole (TMP-SMZ) or placebo, 342 were evaluable for occurrence of infection or bacteremia."5.05Trimethoprim-sulfamethoxazole in the prevention of infection in neutropenic patients. EORTC International Antimicrobial Therapy Project Group. ( , 1984)
"Oral trimethoprim-sulfamethoxazole (Bactrim) plus erythromycin (TMZ-E) was tested versus placebo (P) as prophylaxis for bacterial infection in a randomized, double-blind trial in adult cancer patients receiving cytotoxic chemotherapy expected to result in significant neutropenia."5.05Prophylaxis of fever and infection in adult cancer patients. A placebo-controlled trial of oral trimethoprim-sulfamethoxazole plus erythromycin. ( Carr, DJ; Johnson, A; Kramer, BS; Pizzo, PA; Rand, KH; Robichaud, KJ; Yucha, JB, 1984)
"The efficacy of orally administered trimethoprim/sulfamethoxazole for infection prevention following induction chemotherapy was evaluated in 43 patients with acute leukemia."5.05Oral trimethoprim/sulfamethoxazole in attempt to prevent infection after induction chemotherapy for acute leukemia. ( Arlin, Z; Armstrong, D; Clarkson, B; Gee, T; Henry, SA; Kempin, S, 1984)
"We conducted a prospective, controlled, randomized trial of oral trimethoprim-sulfamethoxazole treatment in patients with acute leukemia receiving consolidation chemotherapy."5.05Prophylactic trimethoprim-sulfamethoxazole during consolidation chemotherapy for acute leukemia: a controlled trial. ( Armstrong, D; Fialk, MA; Lange, M; Singer, C; Szatrowski, TH; Weiser, B, 1981)
"The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days."3.67Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984)
"6 out of 7 patients with severe neutropenia associated with the use of amodiaquine for malaria prophylaxis amodiaquine (400 mg weekly) plus proguanil (200 mg daily); 1 of these patients had also taken cotrimoxazole and another had taken sulphaguanidine."3.67Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria. ( Bunch, C; Edwards, G; Hatton, CS; Pasvol, G; Peto, TE; Russell, SJ; Singer, CR; Winstanley, P, 1986)
"In patients with AIDS, oral therapy with trimethoprim-sulfamethoxazole and with trimethoprim-dapsone are equally effective for mild-to-moderate first episodes of P."2.67Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone. ( Benowitz, N; Hopewell, PC; Lee, B; Leoung, G; Medina, I; Mills, J; Modin, G; Wofsy, CB, 1990)
"Norfloxacin has been compared to placebo (136 patients), sulfamethoxazole plus trimethoprim (SXT, 72 patients) and oral vancomycin plus colistin (V/C, 61 patients) for the prevention of alimentary tract-associated infections during and after induction chemotherapy."2.66The tolerability profile of prophylactic norfloxacin in neutropenic patients. ( Corrado, ML; Hesney, M; Struble, WE, 1988)
"Ketoconazole or miconazole was randomly administered to 42 and 46 neutropenic patients respectively."2.65Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. ( Cruciani, M; Klastersky, J; Meunier-Carpentier, F, 1983)
"One hundred children with cancer and bacterial sepsis were observed for one month after completion of antibiotic treatment for subsequent episodes of infection."1.27Post-sepsis prophylaxis in cancer patients. ( Hughes, WT; Patterson, G, 1984)
"Thrombocytopenia was noted between the seventh and 16th day (mean, 10."1.26Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children. ( Asmar, BI; Dajani, AS; Maqbool, S, 1981)

Research

Studies (49)

TimeframeStudies, this research(%)All Research%
pre-199044 (89.80)18.7374
1990's3 (6.12)18.2507
2000's0 (0.00)29.6817
2010's2 (4.08)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Vinker-Shuster, M1
Stepensky, P1
Temper, V1
Shayovitz, V1
Masarwa, R1
Averbuch, D1
Maschmeyer, G1
CarratalĂ , J1
Buchheidt, D1
Hamprecht, A1
Heussel, CP1
Kahl, C1
Lorenz, J1
Neumann, S1
Rieger, C1
Ruhnke, M1
Salwender, H1
Schmidt-Hieber, M1
Azoulay, E1
Starke, ID1
Donnelly, P1
Catovsky, D2
Darrell, J2
Johnson, SA1
Goldman, JM2
Galton, DA2
Meunier-Carpentier, F2
Cruciani, M1
Klastersky, J2
Principi, N1
Marchisio, P1
Biasini, A1
Dalla Villa, A1
Biasini, G1
Riben, PD1
Louie, TJ3
Lank, BA1
Kornachuk, E1
Gurwith, MJ1
Harding, GK1
Ronald, AR1
Zinner, SH1
Leahy, MF1
Humble, MW1
Wolff, LJ1
Kramer, BS1
Carr, DJ1
Rand, KH1
Pizzo, PA1
Johnson, A1
Robichaud, KJ1
Yucha, JB1
Henry, SA1
Armstrong, D2
Kempin, S1
Gee, T1
Arlin, Z1
Clarkson, B1
Hughes, WT1
Patterson, G1
Scaglione, C1
Tormena, AM1
Pavlovsky, S1
Kauffman, CA1
Liepman, MK1
Bergman, AG1
Mioduszewski, J1
Beutler, SM1
Barth, NM1
Bayer, AS1
Rubin, RH1
Swartz, MN1
Ekert, H1
Jurk, IH1
Waters, KD1
Tiedemann, K1
Lanzkowsky, P1
Schaeffer, J1
Bradley, PP1
Warden, GD1
Maxwell, JG1
Rothstein, G1
Weiser, B1
Lange, M1
Fialk, MA1
Singer, C1
Szatrowski, TH1
Malarme, M1
Guess, HA1
Cohen, MS1
Stockman, JA1
Asmar, BI1
Maqbool, S1
Dajani, AS1
Giamarellou, H1
Hawkins, T1
Carter, JM1
Romeril, KR1
Jackson, SR1
Green, GJ1
Enno, A1
Hows, J1
Bateman, CJ1
Geddes, AM1
Ball, AP1
Farrell, ID1
Marty, M1
Gisselbrecht, C1
Samson-Lepors, MJ1
Melikian, V1
Falk, R1
Shah, CP1
Sanghavi, NG1
Amin, VC1
Medina, I1
Mills, J1
Leoung, G1
Hopewell, PC1
Lee, B1
Modin, G1
Benowitz, N1
Wofsy, CB1
Hatton, CS1
Peto, TE1
Bunch, C1
Pasvol, G1
Russell, SJ1
Singer, CR1
Edwards, G1
Winstanley, P1
Figueredo, AT1
Hryniuk, WM1
Strautmanis, I1
Frank, G1
Rendell, S1
Koletzko, B1
Wendel, U1
Bremer, HJ1
Verhoef, J1
Rozenberg-Arska, M1
Dekker, A1
De Pauw, BE1
Novakova, IR1
Ubachs, E1
Hoes, A1
Stalpers, L1
Verhagen, C1
Corrado, ML1
Struble, WE1
Hesney, M1
Bow, EJ2
Rayner, E2
Scott, BA1
Wells, CL1
Ferrieri, P1
Weisdorf, DJ1
Rhame, FS1
Harris, GJ1
Franson, TR1
Unowsky, J1
Chandrasekar, PH1
DeLorenzo, W1
Levine, DP1
Riou, B2
Richard, C2
Rimailho, A2
Auzepy, P2
Coquin, Y1
Rottman, E1
Gordon-Smith, EC1
Spiers, AS1
Tattersall, MH1
Gaya, H1

Reviews

3 reviews available for trimethoprim and Neutropenia

ArticleYear
Supportive care for children with cancer. Guidelines of the Childrens Cancer Study Group. Use of prophylactic antibiotics.
    The American journal of pediatric hematology/oncology, 1984,Fall, Volume: 6, Issue:3

    Topics: Adolescent; Adult; Amphotericin B; Anti-Bacterial Agents; Bacterial Infections; Candidiasis; Child;

1984
Empiric therapy for infections in the febrile, neutropenic, compromised host.
    The Medical clinics of North America, 1995, Volume: 79, Issue:3

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic;

1995
Co-trimoxazole for the treatment of serious infections.
    The Journal of antimicrobial chemotherapy, 1979, Volume: 5, Issue:B

    Topics: Bacterial Infections; Brucellosis; Carrier State; Drug Combinations; Humans; Intestinal Diseases; Ma

1979

Trials

20 trials available for trimethoprim and Neutropenia

ArticleYear
Gram-negative Bacteremia in Children With Hematologic Malignancies and Following Hematopoietic Stem Cell Transplantation: Epidemiology, Resistance, and Outcome.
    Journal of pediatric hematology/oncology, 2019, Volume: 41, Issue:8

    Topics: Adolescent; Allografts; Bacteremia; Child; Child, Preschool; Drug Combinations; Drug Resistance, Bac

2019
Co-trimoxazole alone for prevention of bacterial infection in patients with acute leukaemia.
    Lancet (London, England), 1982, Jan-02, Volume: 1, Issue:8262

    Topics: Acute Disease; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Colistin; Drug Combinati

1982
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1

    Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Keto

1983
Reduction in mortality from gram-negative sepsis in neutropenic patients receiving trimethoprim/sulfamethoxazole therapy.
    Cancer, 1983, May-01, Volume: 51, Issue:9

    Topics: Adult; Aged; Agranulocytosis; Bacterial Infections; Clinical Trials as Topic; Female; Humans; Leukem

1983
Prophylaxis of bacterial infections with oral antibiotics in neutropenic patients. Lessons from the last two EORTC trials and prospects for the future.
    Schweizerische medizinische Wochenschrift. Supplementum, 1983, Volume: 14

    Topics: Administration, Oral; Agranulocytosis; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections;

1983
Trimethoprim-sulfamethoxazole in the prevention of infection in neutropenic patients. EORTC International Antimicrobial Therapy Project Group.
    The Journal of infectious diseases, 1984, Volume: 150, Issue:3

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic; Drug Combina

1984
Prophylaxis of fever and infection in adult cancer patients. A placebo-controlled trial of oral trimethoprim-sulfamethoxazole plus erythromycin.
    Cancer, 1984, Jan-15, Volume: 53, Issue:2

    Topics: Adolescent; Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; D

1984
Oral trimethoprim/sulfamethoxazole in attempt to prevent infection after induction chemotherapy for acute leukemia.
    The American journal of medicine, 1984, Volume: 77, Issue:4

    Topics: Acute Disease; Administration, Oral; Adolescent; Adult; Antineoplastic Agents; Drug Combinations; Dr

1984
[Prophylactic controlled trials with cotrimoxazole in afebrile neutropenic patients with malignant hemopathies].
    Sangre, 1982, Volume: 27, Issue:5

    Topics: Adult; Agranulocytosis; Child; Clinical Trials as Topic; Drug Combinations; Fever; Humans; Infection

1982
Trimethoprim/sulfamethoxazole prophylaxis in neutropenic patients. Reduction of infections and effect on bacterial and fungal flora.
    The American journal of medicine, 1983, Volume: 74, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacteria; Bacterial Infections; Drug Resistance

1983
Prophylactic co-trimoxazole and lactobacilli preparation in neutropenic patients.
    Medical and pediatric oncology, 1980, Volume: 8, Issue:1

    Topics: Agranulocytosis; Anti-Bacterial Agents; Antifungal Agents; Bacterial Infections; Biological Products

1980
Prophylactic trimethoprim-sulfamethoxazole during consolidation chemotherapy for acute leukemia: a controlled trial.
    Annals of internal medicine, 1981, Volume: 95, Issue:4

    Topics: Acute Disease; Adult; Aged; Antineoplastic Agents; Bacterial Infections; Clinical Trials as Topic; D

1981
Vancomycin plus gentamicin and cotrimoxazole for prevention of infections in neutropenic cancer patients (a comparative, placebo-controlled pilot study).
    European journal of cancer & clinical oncology, 1981, Volume: 17, Issue:12

    Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Clinical

1981
Co-trimoxazole for prevention of infection in acute leukaemia.
    Lancet (London, England), 1978, Aug-19, Volume: 2, Issue:8086

    Topics: Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Colistin; Cross Infection;

1978
Oral therapy for Pneumocystis carinii pneumonia in the acquired immunodeficiency syndrome. A controlled trial of trimethoprim-sulfamethoxazole versus trimethoprim-dapsone.
    The New England journal of medicine, 1990, Sep-20, Volume: 323, Issue:12

    Topics: Acquired Immunodeficiency Syndrome; Administration, Oral; Adult; Chemical and Drug Induced Liver Inj

1990
Co-trimoxazole prophylaxis during high-dose chemotherapy of small-cell lung cancer.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1985, Volume: 3, Issue:1

    Topics: Aged; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Small Cell; Cats; Cisplati

1985
Prevention of infection in patients with acute nonlymphocytic leukemia by several drug treatment regimens.
    Haematology and blood transfusion, 1987, Volume: 30

    Topics: Acute Disease; Adult; Anti-Infective Agents; Ciprofloxacin; Clinical Trials as Topic; Colistin; Drug

1987
The tolerability profile of prophylactic norfloxacin in neutropenic patients.
    European journal of cancer & clinical oncology, 1988, Volume: 24 Suppl 1

    Topics: Agranulocytosis; Bacterial Infections; Clinical Trials as Topic; Colistin; Diarrhea; Gastrointestina

1988
Comparison of norfloxacin with cotrimoxazole for infection prophylaxis in acute leukemia. The trade-off for reduced gram-negative sepsis.
    The American journal of medicine, 1988, Volume: 84, Issue:5

    Topics: Acute Disease; Adult; Antineoplastic Agents; Bacterial Infections; Clinical Trials as Topic; Drug Co

1988
Selective gut decontamination with nalidixic acid or trimethoprim-sulfamethoxazole for infection prophylaxis in neutropenic cancer patients: relationship of efficacy to antimicrobial spectrum and timing of administration.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:4

    Topics: Agranulocytosis; Antineoplastic Agents; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dr

1987

Other Studies

26 other studies available for trimethoprim and Neutropenia

ArticleYear
Diagnosis and antimicrobial therapy of lung infiltrates in febrile neutropenic patients (allogeneic SCT excluded): updated guidelines of the Infectious Diseases Working Party (AGIHO) of the German Society of Hematology and Medical Oncology (DGHO).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2015, Volume: 26, Issue:1

    Topics: Anti-Infective Agents; Bronchoalveolar Lavage Fluid; Drug Combinations; Fever; Humans; Lung; Lung Di

2015
Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole).
    Acta paediatrica Scandinavica, 1984, Volume: 73, Issue:6

    Topics: Agranulocytosis; Amoxicillin; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination;

1984
Outbreak of co-trimoxazole- and gentamicin-resistant Klebsiella aerogenes bacteremia in neutropenic patients receiving oral co-trimoxazole prophylaxis.
    Australian and New Zealand journal of medicine, 1983, Volume: 13, Issue:6

    Topics: Aged; Drug Combinations; Drug Resistance, Microbial; Drug Therapy, Combination; Female; Gentamicins;

1983
Post-sepsis prophylaxis in cancer patients.
    Cancer, 1984, Jan-01, Volume: 53, Issue:1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Bacterial Infections; Child; Drug Therapy, Combinati

1984
Preventing infection in neutropenic cancer patients.
    The Western journal of medicine, 1983, Volume: 138, Issue:5

    Topics: Agranulocytosis; Bacterial Infections; Humans; Immunosuppression Therapy; Leukemia; Neutropenia; Sul

1983
Trimethoprim-sulfamethoxazole.
    The New England journal of medicine, 1980, Aug-21, Volume: 303, Issue:8

    Topics: Administration, Oral; Adult; Bacteria; Child; Drug Combinations; Drug Interactions; Drug Resistance,

1980
Prophylactic use of TMP-SMZ in leukemia.
    The Journal of pediatrics, 1982, Volume: 100, Issue:6

    Topics: Agranulocytosis; Child; Drug Combinations; Humans; Leukemia, Lymphoid; Neutropenia; Pulmonary Fibros

1982
Neutropenia and thrombocytopenia in renal allograft recipients treated with trimethoprim-sulfamethoxazole.
    Annals of internal medicine, 1980, Volume: 93, Issue:4

    Topics: Adult; Agranulocytosis; Azathioprine; Bone Marrow; Drug Combinations; Drug Synergism; Humans; Kidney

1980
Drug treatment of otitis media and urinary tract infections.
    American journal of diseases of children (1960), 1982, Volume: 136, Issue:11

    Topics: Agranulocytosis; Child; Humans; Neutropenia; Otitis Media; Sulfamethoxazole; Thrombocytopenia; Trime

1982
Trimethoprim-sulfamethoxazole therapy. Everything's not turning up roses.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:12

    Topics: Bacterial Infections; Child; Drug Combinations; Humans; Neutropenia; Sulfamethoxazole; Thrombocytope

1981
Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children.
    American journal of diseases of children (1960), 1981, Volume: 135, Issue:12

    Topics: Amoxicillin; Anemia; Blood; Child; Child, Preschool; Drug Therapy, Combination; Eosinophilia; Female

1981
Severe trimethoprim induced neutropenia and thrombocytopenia.
    The New Zealand medical journal, 1993, Jun-23, Volume: 106, Issue:958

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Neutropenia; Thrombocytopenia; Trimethoprim

1993
Prophylactic co-trimoxazole in leukaemia.
    Lancet (London, England), 1978, Sep-16, Volume: 2, Issue:8090

    Topics: Drug Combinations; Humans; Infection Control; Leukemia, Myeloid, Acute; Neutropenia; Sulfamethoxazol

1978
[Treatment of febrile episodes in the neutropenic subject: use of the combination of amikacin-colistin-trimethoprim-sulphamethoxazole].
    La Nouvelle presse medicale, 1979, Oct-31, Volume: 8, Issue:42

    Topics: Agranulocytosis; Amikacin; Colistin; Drug Therapy, Combination; Fever; Humans; Kanamycin; Neutropeni

1979
Treatment of febrile episodes in neutropenic patients.
    Scottish medical journal, 1976, Volume: 21, Issue:2

    Topics: Agranulocytosis; Anti-Bacterial Agents; Clindamycin; Drug Combinations; Fever; Humans; Immunosuppres

1976
Efficacy and toxicity of trimethoprimsulfamethoxazole in typhoid fever.
    The Journal of the Association of Physicians of India, 1975, Volume: 23, Issue:5

    Topics: Adolescent; Adult; Child; Chloramphenicol; Drug Combinations; Humans; Neutropenia; Sulfamethoxazole;

1975
Frequency of severe neutropenia associated with amodiaquine prophylaxis against malaria.
    Lancet (London, England), 1986, Feb-22, Volume: 1, Issue:8478

    Topics: Acute Disease; Adult; Agranulocytosis; Amodiaquine; Drug Combinations; Drug Therapy, Combination; Fe

1986
Lithium for treatment of neutropenia in glycogen storage disease type Ib.
    The Journal of pediatrics, 1986, Volume: 109, Issue:5

    Topics: Agranulocytosis; Chlorides; Drug Combinations; Drug Therapy, Combination; Female; Glycogen Storage D

1986
Co-trimoxazole in patients with haematological malignancies: a review of 10-years' clinical experience.
    Current medical research and opinion, 1988, Volume: 11, Issue:1

    Topics: Anti-Infective Agents; Drug Combinations; Humans; Intestines; Leukemia; Neutropenia; Opportunistic I

1988
The importance of surveillance stool cultures during periods of severe neutropenia.
    Infection control : IC, 1987, Volume: 8, Issue:8

    Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Bone Marrow Transplantation; Child; Drug Combinations

1987
Neutropenia induced by short-term oral trimethoprim-sulfamethoxazole therapy; case report.
    Wisconsin medical journal, 1986, Volume: 85, Issue:3

    Topics: Adult; Agranulocytosis; Anti-Infective Agents, Urinary; Drug Combinations; Female; Humans; Neutropen

1986
In vitro and in vivo activity of coumermycin and other antibacterial agents against methicillin-resistant strains of Staphylococcus aureus.
    Chemotherapy, 1986, Volume: 32, Issue:6

    Topics: Aminocoumarins; Animals; Anti-Bacterial Agents; Coumarins; Drug Combinations; Female; Fusidic Acid;

1986
Potential risks of trimethoprim-sulfamethoxazole prophylaxis in neutropenic patients.
    The Journal of infectious diseases, 1985, Volume: 151, Issue:5

    Topics: Agranulocytosis; Drug Combinations; Drug Resistance, Microbial; Humans; Neutropenia; Risk; Sulfameth

1985
[Antibiotic resistance of Escherichia coli. Importance of the resistance to trimethoprim-sulfamethoxazole].
    Annales de medecine interne, 1985, Volume: 136, Issue:5

    Topics: Anti-Bacterial Agents; Bacterial Infections; Drug Combinations; Drug Resistance, Microbial; Escheric

1985
Treatment of aplastic anemias.
    Hospital practice (Office ed.), 1985, May-15, Volume: 20, Issue:5

    Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Antifungal Agents; Antilymphocyte Serum; Bone Marrow

1985
Indications for systemic antibiotic prophylaxis in neutropenic patients.
    British medical journal, 1974, Nov-23, Volume: 4, Issue:5942

    Topics: Adult; Agranulocytosis; Anti-Bacterial Agents; Biguanides; Blood Cell Count; Carbenicillin; Cephalot

1974