trimethoprim has been researched along with Neural Tube Defects in 1 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Neural Tube Defects: Congenital malformations of the central nervous system and adjacent structures related to defective neural tube closure during the first trimester of pregnancy generally occurring between days 18-29 of gestation. Ectodermal and mesodermal malformations (mainly involving the skull and vertebrae) may occur as a result of defects of neural tube closure. (From Joynt, Clinical Neurology, 1992, Ch55, pp31-41)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Abdullah, NL | 1 |
| Gunasekaran, R | 1 |
| Mohd-Zin, SW | 1 |
| Lim, BH | 1 |
| Maniam, P | 1 |
| Mohd-Salleh, AS | 1 |
| Thong, MK | 1 |
| Chik, Z | 1 |
| Nordin, N | 1 |
| Omar, Z | 1 |
| Engkasan, JP | 1 |
| Ganesan, D | 1 |
| Aiezzah, ZN | 1 |
| Ahmad-Annuar, A | 1 |
| Abdul-Aziz, NM | 1 |
1 other study available for trimethoprim and Neural Tube Defects
| Article | Year |
|---|---|
Cranial neural tube defect after trimethoprim exposure.
Topics: Animals; Anti-Infective Agents, Urinary; Female; Germany; Japan; Malaysia; Male; Mice; Neural Tube D | 2018 |