trimethoprim has been researched along with Nervous System Disorders in 9 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Here we describe the occurrence of severe combined immunodeficiency (SCID) with megaloblastic anemia, leukopenia, atypical hemolytic uremic syndrome, and neurologic abnormalities in which hydroxocobalamin and folate therapy provided partial immune reconstitution." | 3.79 | Severe combined immunodeficiency resulting from mutations in MTHFD1. ( Baluarte, HJ; Bergqvist, AG; Ganesh, J; Heltzer, M; Keller, MD; Orange, JS; Paessler, M; Rosenblatt, DS; Watkins, D, 2013) |
| "Whipple's disease is a systemic bacterial infection that once was uniformly fatal and now is treatable with several different antibiotics in most cases." | 2.37 | Whipple's disease. ( Feldman, M, 1986) |
| "Treatment with trimethoprim-sulfamethoxazole with rifampin (5 patients) or tetracycline (1 patient) produced excellent clinical and laboratory response." | 1.27 | Nervous system brucellosis: diagnosis and treatment. ( Al-Kawi, MZ; Bashir, R; Harder, EJ; Jinkins, J, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 8 (88.89) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Keller, MD | 1 |
| Ganesh, J | 1 |
| Heltzer, M | 1 |
| Paessler, M | 1 |
| Bergqvist, AG | 1 |
| Baluarte, HJ | 1 |
| Watkins, D | 1 |
| Rosenblatt, DS | 1 |
| Orange, JS | 1 |
| Mandal, BK | 1 |
| Feldman, M | 1 |
| Davis, RE | 1 |
| Bahemuka, M | 1 |
| Shemena, AR | 1 |
| Panayiotopoulos, CP | 1 |
| al-Aska, AK | 1 |
| Obeid, T | 1 |
| Daif, AK | 1 |
| Feurle, GE | 1 |
| Bashir, R | 1 |
| Al-Kawi, MZ | 1 |
| Harder, EJ | 1 |
| Jinkins, J | 1 |
| Osuntokun, BO | 1 |
| Bademosi, O | 1 |
| Ogunremi, K | 1 |
| Wright, SG | 1 |
| Warot, P | 1 |
| Lambert, P | 1 |
3 reviews available for trimethoprim and Nervous System Disorders
| Article | Year |
|---|---|
Typhoid and paratyphoid fever.
Topics: Carrier State; Chloramphenicol; Drug Combinations; Drug Resistance, Microbial; Humans; Intestinal Pe | 1979 |
Whipple's disease.
Topics: Bacterial Infections; Diagnosis, Differential; Drug Combinations; Eye Diseases; Heart Diseases; Hema | 1986 |
Clinical chemistry of folic acid.
Topics: Absorption; Aged; Alcoholism; Anemia, Sickle Cell; Anticonvulsants; Arthritis, Rheumatoid; Biologica | 1986 |
6 other studies available for trimethoprim and Nervous System Disorders
| Article | Year |
|---|---|
Severe combined immunodeficiency resulting from mutations in MTHFD1.
Topics: 3-Hydroxyacyl CoA Dehydrogenases; Anemia, Megaloblastic; Bone Marrow Examination; Cardiomyopathies; | 2013 |
Neurological syndromes of brucellosis.
Topics: Adult; Brucella abortus; Brucellosis; Cerebrovascular Disorders; Drug Combinations; Drug Resistance, | 1988 |
Pathophysiology of diarrhea in patients with familial amyloid neuropathy.
Topics: Adult; Aged; Amyloidosis; Breath Tests; Celiac Disease; Diarrhea; Drug Combinations; Female; Gastric | 1987 |
Nervous system brucellosis: diagnosis and treatment.
Topics: Adult; Aged; Animals; Brucellosis; Drug Combinations; Female; Humans; Male; Middle Aged; Nervous Sys | 1985 |
Neuropsychiatric manifestations of typhoid fever in 959 patients.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chloramphenicol; Female; Humans; Infant; Male; Men | 1972 |
[Study of the association of sulfamethoxazole and trimethoprim in surinfections in neurologic pathology].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Cross Infection; Female; Folic Acid Antagonists; Hum | 1971 |