Page last updated: 2024-11-05

trimethoprim and Mycoses

trimethoprim has been researched along with Mycoses in 32 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Mycoses: Diseases caused by FUNGI.

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of norfloxacin were compared with those of placebo, vancomycin-polymyxin, and trimethoprim-sulfamethoxazole (TMP/SMX) for prophylaxis of bacterial infections in granulocytopenic patients."9.06Norfloxacin for prevention of bacterial infections in granulocytopenic patients. ( Bartlett, J; Champlin, RE; Deresinski, S; Finley, RS; Ho, WG; Joshi, JH; Karp, J; Levitt, L; Talbot, G; Winston, DJ, 1987)
"In a comparative study of infection prophylaxis, patients with acute leukemia receiving remission induction therapy were assigned either no prophylaxis, sulfamethoxazole and trimethoprim, ketoconazole, or the combination of sulfamethoxazole and trimethoprim and ketoconazole."9.05Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. ( Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T, 1984)
"The efficacy and safety of norfloxacin were compared with those of placebo, vancomycin-polymyxin, and trimethoprim-sulfamethoxazole (TMP/SMX) for prophylaxis of bacterial infections in granulocytopenic patients."5.06Norfloxacin for prevention of bacterial infections in granulocytopenic patients. ( Bartlett, J; Champlin, RE; Deresinski, S; Finley, RS; Ho, WG; Joshi, JH; Karp, J; Levitt, L; Talbot, G; Winston, DJ, 1987)
"Eighty-four cancer patients at risk of infection because of neutropenia were randomized to receive nalidixic acid as an alternative to trimethoprim-sulfamethoxazole (TMP-SMX) for infection prophylaxis."5.06Selective gut decontamination with nalidixic acid or trimethoprim-sulfamethoxazole for infection prophylaxis in neutropenic cancer patients: relationship of efficacy to antimicrobial spectrum and timing of administration. ( Bow, EJ; Louie, TJ; Rayner, E; Scott, BA, 1987)
"In a comparative study of infection prophylaxis, patients with acute leukemia receiving remission induction therapy were assigned either no prophylaxis, sulfamethoxazole and trimethoprim, ketoconazole, or the combination of sulfamethoxazole and trimethoprim and ketoconazole."5.05Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two. ( Bodey, GP; Estey, E; Fainstein, V; Freireich, EJ; Keating, M; Maksymiuk, A; McCredie, KB; Smith, T, 1984)
"Sixty-two profoundly granulocytopenic patients with acute leukemia undergoing induction chemotherapy were prospectively randomized to receive either trimethoprim-sulfamethoxazole plus nystatin or nalidixic acid plus nystatin for prevention of infection."5.05Selective antimicrobial modulation as prophylaxis against infection during granulocytopenia: trimethoprim-sulfamethoxazole vs. nalidixic acid. ( Crowley, J; de Jongh, CA; Newman, KA; Schimpff, SC; Wade, JC; Wiernik, PH, 1983)
" From the published evidence, the most promising associations are, for staphylococcal infections, gentamicin, erythromycin, kanamycin and fusidic acid."4.76Clinical use of rifampicin in combination for non-mycobacterial infections: a survey of published evidence. ( Fowst, G; Nessi, R, 1979)
"Ketoconazole or miconazole was randomly administered to 42 and 46 neutropenic patients respectively."2.65Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients. ( Cruciani, M; Klastersky, J; Meunier-Carpentier, F, 1983)
"Although the incidence of bacterial infections in the two groups was not statistically significantly different, almost twice as many bacterial infections were observed in the group that received the short course of empirical therapy."2.65Empirical antibacterial therapy in febrile, granulocytopenic bone marrow transplant patients. ( Goldman, AI; Kersey, J; McGlave, P; Peterson, PK; Ramsay, NK; Rhame, F, 1984)
" The long-term use of trimethoprim-sulfamethoxazole and ketoconazole as a preventive therapy for infections has also been evaluated."1.28Incidence, severity, and prevention of infections in chronic granulomatous disease. ( Fischer, A; Griscelli, C; Mouy, R; Seger, R; Vilmer, E, 1989)

Research

Studies (32)

TimeframeStudies, this research(%)All Research%
pre-199029 (90.63)18.7374
1990's2 (6.25)18.2507
2000's1 (3.13)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kocatürk, T1
Pineda, R1
Green, LK1
Azar, DT1
Estey, E1
Maksymiuk, A1
Smith, T1
Fainstein, V1
Keating, M1
McCredie, KB1
Freireich, EJ1
Bodey, GP1
Watson, JG1
Jameson, B1
Powles, RL1
McElwain, TJ1
Lawson, DN1
Judson, I1
Morgenstern, GR1
Lumley, H1
Kay, HE1
Rogers, TR1
Meunier-Carpentier, F1
Cruciani, M1
Klastersky, J1
Bow, EJ2
Louie, TJ3
Riben, PD2
McNaughton, RD1
Harding, GK1
Ronald, AR2
Winston, DJ2
Ho, WG2
Champlin, RE2
Gale, RP1
Peterson, PK1
McGlave, P1
Ramsay, NK1
Rhame, F1
Goldman, AI1
Kersey, J1
Hendriks, WD1
Sizoo, W1
Löwenberg, B1
Hagenbeek, A1
Okafor, BC1
Gugnani, HC1
Kauffman, CA1
Liepman, MK1
Bergman, AG1
Mioduszewski, J1
Wade, JC1
de Jongh, CA1
Newman, KA1
Crowley, J1
Wiernik, PH1
Schimpff, SC1
Meares, EM1
Giamarellou, H1
Bambule, J1
Millioud, E1
Grigoriu, D1
Nessi, R1
Fowst, G1
Singh, D1
Kochhar, RC1
Seth, HN1
Havas, L1
Vilde, JL1
Leport, C1
Takabayashi, K1
Koike, T1
Kurasawa, K1
Yamazaki, S1
Sugiyama, T1
Matsumura, R1
Yoshida, H1
Tomioka, H1
Yoshida, S1
Ohshima, H1
Mouy, R1
Fischer, A1
Vilmer, E1
Seger, R1
Griscelli, C1
Günther, I1
Kaben, U1
Dunker, H1
Brijmohan-Günther, R1
Konrad, H1
Karp, J1
Bartlett, J1
Finley, RS1
Joshi, JH1
Talbot, G1
Levitt, L1
Deresinski, S1
Otis, LL1
Terezhalmy, GT1
Rayner, E1
Scott, BA1
Young, LS1
Hughes, WT2
Rivera, GK1
Schell, MJ1
Thornton, D1
Lott, L1
Buchanan, AG1
Rayner, EN1
Parker, SE1
Feldman, S1
Gigliotti, F1
Shenep, J1
Sixbey, J1
Spitzer, G1
Garson, OM1
Marks, MI1
Shapera, RM1
Brazeau, M1
Roy, AD1
Cameron, HM1

Reviews

7 reviews available for trimethoprim and Mycoses

ArticleYear
Infectious complications of bone marrow transplantation.
    Experimental hematology, 1984, Volume: 12, Issue:3

    Topics: Aminoglycosides; Amphotericin B; Anemia, Aplastic; Bacterial Infections; Bone Marrow Transplantation

1984
[Bacteriologic management of patients with decreased resistance].
    Nederlands tijdschrift voor geneeskunde, 1984, Feb-18, Volume: 128, Issue:7

    Topics: Agranulocytosis; Anti-Bacterial Agents; Antisepsis; Bacterial Infections; Drug Combinations; Humans;

1984
Prostatitis and related diseases.
    Disease-a-month : DM, 1980, Volume: 26, Issue:8

    Topics: Acute Disease; Animals; Anti-Bacterial Agents; Bacterial Infections; Bacteriological Techniques; Cal

1980
Empiric therapy for infections in the febrile, neutropenic, compromised host.
    The Medical clinics of North America, 1995, Volume: 79, Issue:3

    Topics: Algorithms; Aminoglycosides; Anti-Bacterial Agents; Bacterial Infections; Clinical Trials as Topic;

1995
Clinical use of rifampicin in combination for non-mycobacterial infections: a survey of published evidence.
    The Journal of international medical research, 1979, Volume: 7, Issue:3

    Topics: Amphotericin B; Cephalosporins; Chloramphenicol; Colistin; Drug Therapy, Combination; Endocarditis,

1979
[Antibiotherapy in chronic familial granulomatosis].
    Pathologie-biologie, 1990, Volume: 38, Issue:4

    Topics: Amphotericin B; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Drug Combination

1990
Prevention of infectious complications in acute lymphoblastic leukemia.
    Seminars in oncology, 1985, Volume: 12, Issue:2

    Topics: Acute Disease; Acyclovir; Anti-Bacterial Agents; Bacterial Infections; Catheterization; Chickenpox;

1985

Trials

10 trials available for trimethoprim and Mycoses

ArticleYear
Infection prophylaxis in acute leukemia. Comparative effectiveness of sulfamethoxazole and trimethoprim, ketoconazole, and a combination of the two.
    Archives of internal medicine, 1984, Volume: 144, Issue:8

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Drug Combinations; Drug Therapy, Combi

1984
Co-trimoxazole versus non-absorbable antibiotics in acute leukaemia.
    Lancet (London, England), 1982, Jan-02, Volume: 1, Issue:8262

    Topics: Acute Disease; Anti-Bacterial Agents; Bone Marrow Transplantation; Clinical Trials as Topic; Colisti

1982
Oral prophylaxis with miconazole or ketoconazole of invasive fungal disease in neutropenic cancer patients.
    European journal of cancer & clinical oncology, 1983, Volume: 19, Issue:1

    Topics: Agranulocytosis; Antifungal Agents; Candidiasis; Drug Combinations; Female; Humans; Imidazoles; Keto

1983
Randomized controlled trial comparing trimethoprim/sulfamethoxazole and trimethoprim for infection prophylaxis in hospitalized granulocytopenic patients.
    The American journal of medicine, 1984, Volume: 76, Issue:2

    Topics: Adult; Agranulocytosis; Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Combinations;

1984
Empirical antibacterial therapy in febrile, granulocytopenic bone marrow transplant patients.
    Antimicrobial agents and chemotherapy, 1984, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Bone Marrow Transpl

1984
Trimethoprim/sulfamethoxazole prophylaxis in neutropenic patients. Reduction of infections and effect on bacterial and fungal flora.
    The American journal of medicine, 1983, Volume: 74, Issue:4

    Topics: Adult; Aged; Agranulocytosis; Antineoplastic Agents; Bacteria; Bacterial Infections; Drug Resistance

1983
Selective antimicrobial modulation as prophylaxis against infection during granulocytopenia: trimethoprim-sulfamethoxazole vs. nalidixic acid.
    The Journal of infectious diseases, 1983, Volume: 147, Issue:4

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Child; Drug Combinations; Female; Hu

1983
Norfloxacin for prevention of bacterial infections in granulocytopenic patients.
    The American journal of medicine, 1987, Jun-26, Volume: 82, Issue:6B

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Bacterial Infections; Drug Combinations; Drug Therapy, Com

1987
Selective gut decontamination with nalidixic acid or trimethoprim-sulfamethoxazole for infection prophylaxis in neutropenic cancer patients: relationship of efficacy to antimicrobial spectrum and timing of administration.
    Antimicrobial agents and chemotherapy, 1987, Volume: 31, Issue:4

    Topics: Agranulocytosis; Antineoplastic Agents; Bacteria; Bacterial Infections; Clinical Trials as Topic; Dr

1987
Successful intermittent chemoprophylaxis for Pneumocystis carinii pneumonitis.
    The New England journal of medicine, 1987, Jun-25, Volume: 316, Issue:26

    Topics: Anti-Infective Agents; Child; Child, Preschool; Drug Administration Schedule; Drug Combinations; Eva

1987

Other Studies

15 other studies available for trimethoprim and Mycoses

ArticleYear
Post-LASIK epithelial dendritic defect associated with Alternaria.
    Cornea, 2007, Volume: 26, Issue:9

    Topics: Alternaria; Amphotericin B; Antifungal Agents; Combined Modality Therapy; Corneal Ulcer; Debridement

2007
Infection complicating bone marrow transplantation: what are the risks and can they be reduced?
    The Journal of hospital infection, 1982, Volume: 3, Issue:2

    Topics: Aminoglycosides; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Bacterial Infections; Blood

1982
Nasal entomophthoromycosis in Nigerian Igbos.
    Tropical and geographical medicine, 1983, Volume: 35, Issue:1

    Topics: Adult; Drug Combinations; Entomophthora; Female; Humans; Male; Middle Aged; Mycoses; Nigeria; Nose D

1983
[Bacterial and fungal rhino-sinusitis].
    Schweizerische Monatsschrift fur Zahnheilkunde = Revue mensuelle suisse d'odonto-stomatologie, 1977, Volume: 87, Issue:11

    Topics: Amphotericin B; Ampicillin; Aspergillus fumigatus; Bacterial Infections; Erythromycin; Humans; Mycos

1977
Rhinoentomophthoromycosis.
    The Journal of laryngology and otology, 1976, Volume: 90, Issue:9

    Topics: Adult; Entomophthora; Fungi; Humans; Male; Mycoses; Nose Diseases; Potassium Iodide; Prednisolone; S

1976
[The treatment of various deep mycoses (South American blastomycosis, nocardiosis, actinomycetoma) with the drug combination sulfamethoxazole+trimethoprim (bactrim, septrin). Review of the literature].
    Mykosen, 1975, Volume: 18, Issue:6

    Topics: Actinomycetales; Actinomycetales Infections; Blastomyces; Blastomycosis; Dapsone; Drug Combinations;

1975
[Pulmonary opportunistic infections in patients with autoimmune diseases].
    Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine, 1989, Volume: 78, Issue:9

    Topics: Adult; Aged; Autoimmune Diseases; Female; Humans; Isoniazid; Lung Diseases, Fungal; Male; Middle Age

1989
Incidence, severity, and prevention of infections in chronic granulomatous disease.
    The Journal of pediatrics, 1989, Volume: 114, Issue:4 Pt 1

    Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Genetic Linkage; Granu

1989
Selective decontamination of the digestive tract and fungal infection in acute leukemia patients.
    Recent results in cancer research. Fortschritte der Krebsforschung. Progres dans les recherches sur le cancer, 1988, Volume: 108

    Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Digestive System; Drug Administration

1988
The granulocytopenic patient: another consideration for antimicrobial prophylaxis.
    Oral surgery, oral medicine, and oral pathology, 1985, Volume: 60, Issue:1

    Topics: Agranulocytosis; Anti-Bacterial Agents; Bacterial Infections; Dental Care for Disabled; Humans; Mout

1985
Management of opportunistic infections complicating the acquired immunodeficiency syndrome.
    The Medical clinics of North America, 1986, Volume: 70, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; Adult; Candidiasis; Cryptococcosis; Drug Combinations; Humans; I

1986
Nystatin prophylaxis of fungal colonization and infection in granulocytopenic patients: correlation of colonization and clinical outcome.
    Clinical and investigative medicine. Medecine clinique et experimentale, 1985, Volume: 8, Issue:2

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anti-Bacterial Agents; Drug Combinations; Female; Fever; H

1985
Lymphoblastic leukemia with marked eosinophilia: a report of two cases.
    Blood, 1973, Volume: 42, Issue:3

    Topics: Adolescent; Blood Cell Count; Bone Marrow Examination; Cytarabine; Eosinophilia; Female; Humans; Kar

1973
Pediatric antimicrobial therapy. V.
    Canadian Medical Association journal, 1973, Sep-01, Volume: 109, Issue:5

    Topics: Amphotericin B; Anti-Infective Agents; Antifungal Agents; Bacterial Infections; Child; Drug Therapy,

1973
Rhinophycomycosis entomophthorae occurring in a chimpanzee in the wild in East Africa.
    The American journal of tropical medicine and hygiene, 1972, Volume: 21, Issue:2

    Topics: Africa, Eastern; Animals; Disease Models, Animal; Female; Fungi; Mycoses; Nose; Nose Diseases; Pan t

1972