trimethoprim has been researched along with Middle Ear Inflammation in 74 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "78 pediatric patients affected by acute otitis media were selected and randomized into two balanced groups of treatment: brodimoprim, at the dosage of 200 mg once-a-day on the first day and of 100 mg once-a-day on the following days, and cefaclor at a dosage of 40 mg/Kg/day in three doses." | 9.07 | Efficacy and tolerability of brodimoprim in bacterial otitis media in children. Controlled study versus cefaclor. ( Bergamini, G; Cantini, L; Dallari, S; Galetti, G; Ghidini, A; Martini, A; Mazzoli, M; Monici Preti, PA, 1993) |
| "Although amoxicillin has long been the preferred drug for treatment of acute otitis media, resistant strains of two relatively common causal organisms have emerged, prompting a search for other antibiotics." | 9.06 | Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media. ( Dulberg, C; Feldman, W; Momy, J, 1988) |
| "We report the hematologic changes in 90 black children who were randomized to receive a 10-day course of either trimethoprim-sulfamethoxazole (TMP-SMZ) or amoxicillin as therapy for acute otitis media." | 9.05 | Similar hematologic changes in children receiving trimethoprim-sulfamethoxazole or amoxicillin for otitis media. ( Doolittle, M; Feldman, S; Hughes, WT; Lott, L; Roberson, P, 1985) |
| "We performed a randomized controlled trial of cefaclor administered twice daily compared with trimethoprim-sulfamethoxazole (TMP-SMZ) administered twice daily for the treatment of acute otitis media." | 9.05 | A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media. ( Feinstein, JC; Johnson, CE; Knapp, LJ; Marchant, CD; Shurin, PA; Turcyzk, VA; Tutihasi, MA; Wasikowski, DE, 1984) |
| "We treated 132 children with acute otitis media in a randomized trial comparing trimethoprim-sulfamethoxazole and ampicillin." | 9.05 | Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media. ( Donner, A; Finkelstein, J; Klein, JO; Pelton, SI; Shurin, PA, 1980) |
| "The tolerabilities of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole (TMP-SMX) suspensions were evaluated in 263 children with otitis media." | 9.05 | Comparative tolerability of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole suspensions in children with otitis media. ( Feder, HM, 1982) |
| "This study was undertaken during the late fall, winter, and early spring months to determine the efficacy of daily trimethoprim/sulfamethoxazole (TMP/SMX) administration in the prevention of recurrent acute otitis media (RAOM) in a specific high-risk pediatric population." | 9.05 | Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. ( Gaskins, JD; Holt, RJ; Kyong, CU; Ward, J; Weart, CW, 1982) |
| "Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection." | 9.04 | Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975) |
| "The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days." | 7.67 | Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984) |
| "Two patients had severe thrombocytopenia while taking trimethoprim-sulfamethoxazole." | 7.66 | Thrombocytopenia secondary to trimethoprim-sulfamethoxazole. ( Hagen, MD; White, RD, 1983) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 7.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media." | 7.65 | Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976) |
| "Eighty adult patients affected by acute bacterial otitis media were selected and randomized into two balanced groups of treatment: 1) brodimoprim 200 mg tablets at the dosage of 2 tablets in single dose on the first day and one tablet on the following days; 2) josamycin 500 mg tablets at the dosage of 3 tablets/day." | 5.07 | Efficacy and tolerability of brodimoprim in otitis. ( Camaioni, A; De Campora, E; Radici, M, 1993) |
| " This open group comparative study was performed either in 68 children affected by bacterial pharyngotonsillitis (37 treated with brodimoprim, 31 with erythromycin 560 mg/kg/8 hours) or in 50 patients affected by otitis media (25 treated with brodimoprim, 25 with amoxicillin/clavulanic acid 50 mg/kg/12 hours) or in 52 patients affected by acute sinusitis (25 treated with brodimoprim, 27 with amoxicillin/clavulanic acid 50 mg/kg/12 hours)." | 5.07 | Efficacy and tolerability of brodimoprim in pediatric infections. ( Bellosta, C; Boccazzi, A; Careddu, P; Tonelli, P, 1993) |
| "78 pediatric patients affected by acute otitis media were selected and randomized into two balanced groups of treatment: brodimoprim, at the dosage of 200 mg once-a-day on the first day and of 100 mg once-a-day on the following days, and cefaclor at a dosage of 40 mg/Kg/day in three doses." | 5.07 | Efficacy and tolerability of brodimoprim in bacterial otitis media in children. Controlled study versus cefaclor. ( Bergamini, G; Cantini, L; Dallari, S; Galetti, G; Ghidini, A; Martini, A; Mazzoli, M; Monici Preti, PA, 1993) |
| "Although amoxicillin has long been the preferred drug for treatment of acute otitis media, resistant strains of two relatively common causal organisms have emerged, prompting a search for other antibiotics." | 5.06 | Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media. ( Dulberg, C; Feldman, W; Momy, J, 1988) |
| "We performed a randomized controlled trial of cefaclor administered twice daily compared with trimethoprim-sulfamethoxazole (TMP-SMZ) administered twice daily for the treatment of acute otitis media." | 5.05 | A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media. ( Feinstein, JC; Johnson, CE; Knapp, LJ; Marchant, CD; Shurin, PA; Turcyzk, VA; Tutihasi, MA; Wasikowski, DE, 1984) |
| "We treated 132 children with acute otitis media in a randomized trial comparing trimethoprim-sulfamethoxazole and ampicillin." | 5.05 | Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media. ( Donner, A; Finkelstein, J; Klein, JO; Pelton, SI; Shurin, PA, 1980) |
| "The tolerabilities of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole (TMP-SMX) suspensions were evaluated in 263 children with otitis media." | 5.05 | Comparative tolerability of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole suspensions in children with otitis media. ( Feder, HM, 1982) |
| "This study was undertaken during the late fall, winter, and early spring months to determine the efficacy of daily trimethoprim/sulfamethoxazole (TMP/SMX) administration in the prevention of recurrent acute otitis media (RAOM) in a specific high-risk pediatric population." | 5.05 | Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole. ( Gaskins, JD; Holt, RJ; Kyong, CU; Ward, J; Weart, CW, 1982) |
| "We report the hematologic changes in 90 black children who were randomized to receive a 10-day course of either trimethoprim-sulfamethoxazole (TMP-SMZ) or amoxicillin as therapy for acute otitis media." | 5.05 | Similar hematologic changes in children receiving trimethoprim-sulfamethoxazole or amoxicillin for otitis media. ( Doolittle, M; Feldman, S; Hughes, WT; Lott, L; Roberson, P, 1985) |
| "Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection." | 5.04 | Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975) |
| "The incidence of hematologic abnormalities was evaluated in 120 children with otitis media treated respectively with cotrimoxazole (trimethoprim-sulfamethoxazole) (group 1), cotrimoxazole plus folinic acid (group 2) and amoxicillin (group 3) in therapeutic doses for ten days." | 3.67 | Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole). ( Biasini, A; Biasini, G; Dalla Villa, A; Marchisio, P; Principi, N, 1984) |
| "Two patients had severe thrombocytopenia while taking trimethoprim-sulfamethoxazole." | 3.66 | Thrombocytopenia secondary to trimethoprim-sulfamethoxazole. ( Hagen, MD; White, RD, 1983) |
| "Penetration into the middle ear of four antibiotics commonly used in treatment of otitis media was studied by administering a single oral dose of amoxicillin, cefaclor, erythromycin-sulfisoxazole, or trimethoprim-sulfamethoxazole to 83 children with chronic serous otitis media." | 3.66 | Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media. ( Klimek, JJ; Krause, PJ; Lehmann, WB; Nightingale, CH; Owens, NJ; Quintiliani, R, 1982) |
| "Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media." | 3.65 | Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976) |
| "Otitis media with effusion is the most common cause of hearing loss in children." | 2.65 | Antimicrobial therapy of chronic otitis media with effusion. ( Healy, GB, 1984) |
| "Antibiotic treatment of acute otitis media (AOM) accounts for a significant number of all antibiotic prescriptions each year." | 2.37 | Dilemmas in primary care: antibiotic treatment of acute otitis media. ( Helling, DK; True, BL, 1986) |
| "Recurrent acute otitis media is common in children." | 1.62 | Recurrent acute otitis media: a survey of current management in England. ( Beasley, C; Bhat, J; Emerson, H; Hampton, T; Hogg, E; Krishnan, M; Lowe, N; Sharma, S; Stevens, K; Whitehall, E, 2021) |
| "Trimethoprim K values were also not affected by model testing sequence (p = 0/760), but were by model type (p = 0." | 1.29 | Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics. ( Canafax, DM; Erdmann, GR; Giebink, GS; Le, CT; Lovdahl, MJ; Russlie, H, 1994) |
| "Antimicrobial treatment of otitis media, especially drug dosing considerations, is largely empiric, with few reported pharmacologic studies of drug distribution into the middle ear." | 1.28 | Experimental animal models for studying antimicrobial pharmacokinetics in otitis media. ( Canafax, DM; Erdmann, GR; Giebink, GS; Juhn, SK; Le, CT; Nonomura, N, 1989) |
| " The small sample volumes were dictated by the chinchilla model of otitis media and our need to collect multiple samples over a 12-h drug dosing interval." | 1.27 | High-performance liquid chromatographic analysis of trimethoprim and sulfamethoxazole in microliter volumes of chinchilla middle ear effusion and serum. ( Canafax, DM; Erdmann, GR; Giebink, GS, 1988) |
| "Acute otitis media is commonly caused by pneumococcus and Hemophilus influenzae." | 1.27 | Developments in diagnosing and treating otitis media. ( Eichenwald, H, 1985) |
| "Thrombocytopenia was noted between the seventh and 16th day (mean, 10." | 1.26 | Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children. ( Asmar, BI; Dajani, AS; Maqbool, S, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 61 (82.43) | 18.7374 |
| 1990's | 9 (12.16) | 18.2507 |
| 2000's | 1 (1.35) | 29.6817 |
| 2010's | 1 (1.35) | 24.3611 |
| 2020's | 2 (2.70) | 2.80 |
| Authors | Studies |
|---|---|
| Hampton, T | 1 |
| Whitehall, E | 1 |
| Beasley, C | 1 |
| Stevens, K | 1 |
| Lowe, N | 1 |
| Hogg, E | 1 |
| Bhat, J | 1 |
| Emerson, H | 1 |
| Krishnan, M | 1 |
| Sharma, S | 1 |
| Taha, A | 1 |
| Adeline, F | 1 |
| Taha, MK | 1 |
| Deghmane, AE | 1 |
| Chi, H | 1 |
| Chiu, NC | 1 |
| Huang, FY | 1 |
| Hsu, CH | 1 |
| Lee, KS | 1 |
| Huang, LM | 1 |
| Hsieh, YC | 1 |
| Katz, L | 1 |
| Bläker, F | 1 |
| Gydé, MC | 1 |
| Principi, N | 1 |
| Marchisio, P | 1 |
| Biasini, A | 1 |
| Dalla Villa, A | 1 |
| Biasini, G | 1 |
| Marks, NJ | 2 |
| Mills, RP | 2 |
| Shaheen, OH | 2 |
| Marchant, CD | 1 |
| Shurin, PA | 4 |
| Turcyzk, VA | 1 |
| Feinstein, JC | 1 |
| Johnson, CE | 1 |
| Wasikowski, DE | 1 |
| Knapp, LJ | 1 |
| Tutihasi, MA | 1 |
| Healy, GB | 1 |
| Goldschmidt, B | 1 |
| Clemente, M | 1 |
| Morera, C | 1 |
| Kohonen, A | 1 |
| Palmgren, O | 1 |
| Renkonen, OV | 1 |
| Nelson, JD | 1 |
| Ginsburg, CM | 1 |
| Mcleland, O | 1 |
| Clahsen, J | 1 |
| Culbertson, MC | 1 |
| Carder, H | 1 |
| Hagen, MD | 1 |
| White, RD | 1 |
| Pelton, SI | 2 |
| Donner, A | 1 |
| Finkelstein, J | 1 |
| Klein, JO | 3 |
| Rubin, RH | 1 |
| Swartz, MN | 1 |
| Thornsberry, C | 1 |
| McDougal, LK | 1 |
| Feder, HM | 1 |
| Feldman, W | 2 |
| Richardson, H | 1 |
| Rennie, B | 1 |
| Dawson, P | 1 |
| Gaskins, JD | 1 |
| Holt, RJ | 1 |
| Kyong, CU | 1 |
| Weart, CW | 1 |
| Ward, J | 1 |
| Guess, HA | 1 |
| Cohen, MS | 1 |
| Klimek, JJ | 2 |
| Bates, TR | 1 |
| Nightingale, C | 1 |
| Lehmann, WB | 2 |
| Ziemniak, JA | 1 |
| Quintiliani, R | 2 |
| Krause, PJ | 1 |
| Owens, NJ | 1 |
| Nightingale, CH | 1 |
| Serra, A | 1 |
| Tringali, G | 1 |
| Toscano, MA | 1 |
| Gismondo, MR | 1 |
| Piaia, F | 1 |
| Asmar, BI | 1 |
| Maqbool, S | 1 |
| Dajani, AS | 1 |
| Hager, C | 1 |
| Bamberg, P | 1 |
| Dorn, G | 1 |
| Adam, D | 1 |
| Jossart, GH | 1 |
| Canafax, DM | 4 |
| Erdmann, GR | 4 |
| Lovdahl, MJ | 2 |
| Russlie, HQ | 1 |
| Juhn, SK | 2 |
| Giebink, GS | 4 |
| Russlie, H | 1 |
| Le, CT | 2 |
| De Campora, E | 1 |
| Radici, M | 1 |
| Camaioni, A | 1 |
| Careddu, P | 1 |
| Bellosta, C | 1 |
| Tonelli, P | 1 |
| Boccazzi, A | 1 |
| Galetti, G | 1 |
| Martini, A | 1 |
| Bergamini, G | 1 |
| Dallari, S | 1 |
| Ghidini, A | 1 |
| Mazzoli, M | 1 |
| Cantini, L | 1 |
| Monici Preti, PA | 1 |
| Barlan, IB | 1 |
| Geha, RS | 1 |
| Schneider, LC | 1 |
| Cooper, J | 1 |
| Inman, JS | 1 |
| Dawson, AF | 1 |
| Stewart, IA | 1 |
| Schwartz, R | 1 |
| Rodriguez, WJ | 1 |
| Ross, S | 1 |
| Khan, WN | 1 |
| Gleckman, R | 1 |
| Alvarez, S | 1 |
| Joubert, DW | 1 |
| Wormser, GP | 1 |
| Keusch, GT | 1 |
| Borkenstein, M | 1 |
| Stögmann, W | 1 |
| Gleispach, H | 1 |
| Gutman, LT | 1 |
| Wilfert, CM | 1 |
| Katz, SL | 1 |
| Eichenwald, HF | 1 |
| McCracken, GH | 1 |
| Steele, TW | 1 |
| Rich, GE | 1 |
| Pechere, JC | 1 |
| Quick, CA | 2 |
| Goodey, RJ | 1 |
| Bowers, M | 1 |
| Vâta, A | 1 |
| Dimitriu, S | 1 |
| Turcu, T | 1 |
| Scheifele, D | 1 |
| Cameron, GG | 1 |
| Pomahac, AC | 1 |
| Johnston, MT | 1 |
| Steinböck, VH | 1 |
| Sischka, O | 1 |
| Solar Boga, A | 1 |
| Fontaiña Martinez, M | 1 |
| Bello Fernandez, A | 1 |
| Arteche Guisasola, JL | 1 |
| Rodriguez Valcarcel, G | 1 |
| Hussain, MA | 1 |
| Ali, EM | 1 |
| Ahmed, HS | 1 |
| Tilden, ME | 1 |
| Rosenbaum, JT | 1 |
| Fraunfelder, FT | 1 |
| Stoddard, J | 1 |
| DeAngelis, C | 1 |
| Nonomura, N | 1 |
| Coffey, JD | 1 |
| Killelea, DE | 1 |
| Momy, J | 1 |
| Dulberg, C | 1 |
| Pestalozza, G | 1 |
| Romagnoli, M | 1 |
| Tessitore, E | 1 |
| Formica, U | 1 |
| Van Hare, GF | 1 |
| True, BL | 1 |
| Helling, DK | 1 |
| Godfrey, AA | 1 |
| Keenan, TD | 1 |
| Summerfield, M | 1 |
| Eichenwald, H | 1 |
| Moorhouse, EC | 1 |
| Hickey, MP | 1 |
| O'Hanrahan, MT | 1 |
| Clarke, PC | 1 |
| Backhouse, CI | 1 |
| Woods, P | 1 |
| Feldman, S | 1 |
| Doolittle, M | 1 |
| Lott, L | 1 |
| Roberson, P | 1 |
| Hughes, WT | 1 |
| Wallace, RB | 1 |
| Marsh, BT | 1 |
| Talbot, DJ | 1 |
| Wagner, D | 1 |
| Heynen, U | 1 |
| Salzberg, R | 1 |
| Lewin, EB | 1 |
| Finland, M | 1 |
| Zalewski, T | 1 |
| Gutkowska, J | 1 |
| Zmudzka, B | 1 |
| Radzikowski, A | 1 |
4 reviews available for trimethoprim and Middle Ear Inflammation
| Article | Year |
|---|---|
Drug therapy reviews: trimethoprim-sulfamethoxazole.
Topics: Acute Disease; Bacteria; Child; Chronic Disease; Diagnostic Errors; Drug Administration Schedule; Dr | 1979 |
Trimethoprim-sulfamethoxazole in the United States.
Topics: Adult; Bacterial Infections; Child; Drug Combinations; Drug Synergism; Dysentery, Bacillary; Humans; | 1979 |
Dilemmas in primary care: antibiotic treatment of acute otitis media.
Topics: Acute Disease; Anti-Bacterial Agents; Drug Combinations; Humans; Otitis Media; Sulfamethoxazole; Tri | 1986 |
[Eusaprim-equivalent to broad spectrum antibiotics].
Topics: Acne Vulgaris; Animals; Anti-Bacterial Agents; Bacteria; Bacterial Infections; Bronchitis; Child; Ch | 1971 |
24 trials available for trimethoprim and Middle Ear Inflammation
| Article | Year |
|---|---|
A double-blind comparative study of trimethoprim-polymyxin B versus trimethoprim-sulfacetamide-polymyxin B otic solutions in the treatment of otorrhea.
Topics: Aged; Bacterial Infections; Child; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; | 1981 |
Cotrimoxazole in the treatment of serous otitis. A follow-up report.
Topics: Child; Chlorpheniramine; Clinical Trials as Topic; Drug Combinations; Follow-Up Studies; Humans; Mul | 1983 |
A randomized controlled trial of cefaclor compared with trimethoprim-sulfamethoxazole for treatment of acute otitis media.
Topics: Acute Disease; Cefaclor; Cephalexin; Child, Preschool; Clinical Trials as Topic; Drug Combinations; | 1984 |
Antimicrobial therapy of chronic otitis media with effusion.
Topics: Anti-Bacterial Agents; Child, Preschool; Clinical Trials as Topic; Drug Combinations; Ear Canal; Ear | 1984 |
Concentrations of antimicrobial agents in middle ear fluid, saliva and tears.
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Body Fluids; Cefaclor; Child; Child, Preschool; Ear, | 1981 |
Trimethoprim-sulfamethoxazole compared with ampicillin in the treatment of acute otitis media.
Topics: Acute Disease; Ampicillin; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Exudates and | 1980 |
Comparative tolerability of ampicillin, amoxicillin, and trimethoprim-sulfamethoxazole suspensions in children with otitis media.
Topics: Amoxicillin; Ampicillin; Child; Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; S | 1982 |
A controlled trial of cotrimoxazole therapy in serous otitis media.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug Combinations; Female; H | 1981 |
A trial comparing cefaclor with co-trimoxazole in the treatment of acute otitis media.
Topics: Cefaclor; Cephalexin; Child; Child, Preschool; Clinical Trials as Topic; Double-Blind Method; Drug C | 1982 |
Chemoprophylaxis of recurrent otitis media using trimethoprim/sulfamethoxazole.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Drug Evaluation; Female; Humans; Infant; Male; O | 1982 |
Efficacy and tolerability of brodimoprim in otitis.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Drug Tolerance; Exudates and Transudat | 1993 |
Efficacy and tolerability of brodimoprim in pediatric infections.
Topics: Adolescent; Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Child; Child, Preschool; Cla | 1993 |
Efficacy and tolerability of brodimoprim in bacterial otitis media in children. Controlled study versus cefaclor.
Topics: Acute Disease; Bacterial Infections; Cefaclor; Child; Child, Preschool; Female; Humans; Male; Otitis | 1993 |
A comparison between co-trimoxazole and amoxycillin in the treatment of acute otitis media in general practice.
Topics: Adolescent; Adult; Amoxicillin; Ampicillin; Child; Child, Preschool; Clinical Trials as Topic; Deafn | 1976 |
Comparison of penicillin and trimethoprim-sulfamethoxazole in the treatment of ear, nose and throat infections.
Topics: Adolescent; Bacteria; Bacterial Infections; Clinical Trials as Topic; Drug Combinations; Drug Evalua | 1975 |
Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.
Topics: Administration, Oral; Ampicillin; Bacterial Infections; Body Weight; Child; Clinical Trials as Topic | 1975 |
Trimethoprim-sulfamethoxazole v. amoxicillin in the treatment of acute otitis media.
Topics: Acute Disease; Adolescent; Amoxicillin; Child; Child, Preschool; Clinical Trials as Topic; Double-Bl | 1988 |
General practice studies with combined pivampicillin/pivmecillinam (Miraxid).
Topics: Adolescent; Adult; Aged; Amdinocillin; Amdinocillin Pivoxil; Amoxicillin; Ampicillin; Drug Combinati | 1985 |
Trimethoprim and amoxycillin in acute otitis media.
Topics: Acute Disease; Amoxicillin; Child; Child, Preschool; Clinical Trials as Topic; Female; Humans; Infan | 1985 |
Similar hematologic changes in children receiving trimethoprim-sulfamethoxazole or amoxicillin for otitis media.
Topics: Amoxicillin; Clinical Trials as Topic; Drug Combinations; Female; Humans; Infant; Leukocyte Count; L | 1985 |
A multi-centre general practice clinical evaluation of pivmecillinam plus pivampicillin ('Miraxid') and co-trimoxazole ('Septrin') in respiratory tract infections.
Topics: Adolescent; Adult; Aged; Amdinocillin; Amdinocillin Pivoxil; Ampicillin; Anti-Infective Agents; Bron | 1985 |
Trimethoprim-sulfamethoxazole in the treatment of infections of the ears, nose, and throat.
Topics: Acute Disease; Bacterial Infections; Chronic Disease; Clinical Trials as Topic; Haemophilus Infectio | 1973 |
[Comparative clinical and bacteriological studies with Bactrim and ampicillin in the pediatrics].
Topics: Ampicillin; Anti-Infective Agents; Bacterial Infections; Bronchitis; Child, Preschool; Clinical Tria | 1972 |
Trimethoprim-sulfamethoxazole in the treatment of bacterial infections: report of clinical trials in Japan.
Topics: Acute Disease; Bacterial Infections; Child; Clinical Trials as Topic; Drug Combinations; Drug Resist | 1973 |
46 other studies available for trimethoprim and Middle Ear Inflammation
| Article | Year |
|---|---|
Recurrent acute otitis media: a survey of current management in England.
Topics: Acute Disease; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Child; Drug Resistance, Microb | 2021 |
Haemophilus influenzae drug resistance in France from 2017 to 2021: consideration for treatment of otitis media.
Topics: Amoxicillin; Amoxicillin-Potassium Clavulanate Combination; Anti-Bacterial Agents; Drug Resistance, | 2022 |
Acute otitis media caused by Streptococcus pneumoniae serotype 19A ST320 clone: epidemiological and clinical characteristics.
Topics: Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Child; Child, Preschool; Drug Resistance, Bac | 2018 |
Left otitis media/interna and right maxillary sinusitis in a Percheron mare.
Topics: Analgesics, Non-Narcotic; Animals; Anti-Infective Agents; Dimethyl Sulfoxide; Drug Combinations; Fac | 2006 |
[Antimicrobial therapy using cotrimoxazole].
Topics: Anti-Infective Agents, Urinary; Bacterial Infections; Drug Combinations; Dysentery, Bacillary; Human | 1981 |
Early and late neutropenia in children treated with cotrimoxazole (trimethoprim-sulfamethoxazole).
Topics: Agranulocytosis; Amoxicillin; Child; Child, Preschool; Drug Combinations; Drug Therapy, Combination; | 1984 |
Therapeutic effect of Potesept syrup in infancy and young childhood.
Topics: Bacterial Infections; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Male; Otit | 1984 |
[Open trial using soltrim in otitis media].
Topics: Adolescent; Adult; Drug Combinations; Drug Evaluation; Female; Humans; Male; Middle Aged; Otitis Med | 1983 |
Penetration of trimethoprim--sulfadiazine into middle ear fluid in secretory otitis media.
Topics: Adolescent; Child; Child, Preschool; Ear, Middle; Female; Humans; Infant; Male; Otitis Media; Otitis | 1983 |
Thrombocytopenia secondary to trimethoprim-sulfamethoxazole.
Topics: Acute Disease; Child, Preschool; Drug Therapy, Combination; Female; Folic Acid; Humans; Male; Middle | 1983 |
Trimethoprim-sulfamethoxazole.
Topics: Administration, Oral; Adult; Bacteria; Child; Drug Combinations; Drug Interactions; Drug Resistance, | 1980 |
Ampicillin-resistant Haemophilus influenzae. 2. Therapeutic considerations.
Topics: Adult; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Child; Chloramphenicol; Drug Combinations; Ha | 1982 |
Drug treatment of otitis media and urinary tract infections.
Topics: Agranulocytosis; Child; Humans; Neutropenia; Otitis Media; Sulfamethoxazole; Thrombocytopenia; Trime | 1982 |
Penetration characteristics of trimethoprim-sulfamethoxazole in middle ear fluid of patients with chronic serous otitis media.
Topics: Child; Chronic Disease; Exudates and Transudates; Humans; Otitis Media; Otitis Media with Effusion; | 1980 |
Penetration of amoxicillin, cefaclor, erythromycin-sulfisoxazole, and trimethoprim-sulfamethoxazole into the middle ear fluid of patients with chronic serous otitis media.
Topics: Amoxicillin; Anti-Bacterial Agents; Cefaclor; Child; Child, Preschool; Drug Therapy, Combination; Ea | 1982 |
[Antibacterial activity of a sulfonamide combination (Kelfiprim) in some otorhinolaryngological diseases].
Topics: Acute Disease; Adolescent; Adult; Bacteria; Bacterial Infections; Chronic Disease; Drug Combinations | 1980 |
Hematologic abnormalities after oral trimethoprim-sulfamethoxazole therapy in children.
Topics: Amoxicillin; Anemia; Blood; Child; Child, Preschool; Drug Therapy, Combination; Eosinophilia; Female | 1981 |
The use of co-trimazine once daily in acute otitis media and maxillary sinusitis in children.
Topics: Acute Disease; Child; Child, Preschool; Drug Combinations; Female; Humans; Infant; Male; Maxillary S | 1980 |
Effect of Streptococcus pneumoniae and influenza A virus on middle ear antimicrobial pharmacokinetics in experimental otitis media.
Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Half-Life; Influenza A virus; Mucous Membra | 1994 |
Comparison of two otitis media models for the study of middle ear antimicrobial pharmacokinetics.
Topics: Amoxicillin; Animals; Anti-Bacterial Agents; Chinchilla; Diffusion; Disease Models, Animal; Ear, Mid | 1994 |
Therapy for patients with recurrent infections and low serum IgG3 levels.
Topics: Antibodies; Asthma; Child, Preschool; Evaluation Studies as Topic; Humans; Immunoglobulin G; Immunog | 1993 |
Antimicrobial treatment of otitis media.
Topics: Child; Drug Resistance, Microbial; Humans; Otitis Media; Streptococcus pneumoniae; Sulfamethoxazole; | 1979 |
Treatment of otitis media with trimethoprim-sulfamethoxazole.
Topics: Ampicillin; Child, Preschool; Drug Combinations; Haemophilus influenzae; Humans; Infant; Otitis Medi | 1979 |
[Sulfametrol/trimethoprim (Lidaprim)--modification of the folic acid level and therapeutic value in pediatrics].
Topics: Age Factors; Bronchopneumonia; Child; Child, Preschool; Drug Combinations; Female; Folic Acid; Human | 1979 |
Use of trimethoprim-sulfamethoxazole in otitis media.
Topics: Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; Sulfamethoxazole; Trimethoprim | 1979 |
Use of trimethoprim-sulfamethoxazole in otitis media. Reply.
Topics: Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; Sulfamethoxazole; Trimethoprim | 1979 |
The rational use of antibiotics in general practice.
Topics: Anti-Bacterial Agents; Bacterial Infections; Cephalosporins; Clindamycin; Drug Combinations; Epididy | 1977 |
Trimethoprim-sulfamethoxazole for otitis media.
Topics: Bacterial Infections; Child, Preschool; Drug Combinations; Humans; Infant; Microbial Sensitivity Tes | 1978 |
Combination chemotherapy of infectious diseases. Chairman's summing-up and conclusions.
Topics: Bacterial Infections; Bronchitis; Drug Combinations; Drug Evaluation; Dysentery, Bacillary; Female; | 1975 |
Antibiotic treatment of secretory otitis media assessed by impedence audiometry.
Topics: Ampicillin; Anti-Bacterial Agents; Audiometry; Child; Child, Preschool; Compliance; Doxycycline; Dru | 1975 |
Results of Poteseptyl treatment in enteric, otic and urinary tract infections.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Combinations; Dysentery, Bacillary; Enterocol | 1977 |
Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae.
Topics: Ampicillin; Child, Preschool; Drug Combinations; Female; Haemophilus Infections; Haemophilus influen | 1976 |
[Experience with a combination of sulfametrol and trimethoprim (Lidaprim) in otorhinilaryngologic infections].
Topics: Adolescent; Adult; Age Factors; Aged; Bacterial Infections; Child; Child, Preschool; Drug Therapy, C | 1975 |
[Red-colored urine: a new case].
Topics: Child, Preschool; Diagnosis, Differential; Drug Combinations; False Positive Reactions; Female; Hema | 1991 |
Otitis media in Sudanese children: presentation and bacteriology.
Topics: Adolescent; Child; Child, Preschool; Drug Resistance, Microbial; Female; Hospitals, Teaching; Humans | 1991 |
Systemic sulfonamides as a cause of bilateral, anterior uveitis.
Topics: Child, Preschool; Drug Combinations; Humans; Male; Otitis Media; Sulfamethizole; Trimethoprim; Uveit | 1991 |
Cost analysis of therapy of acute otitis media.
Topics: Acute Disease; Child; Cost-Benefit Analysis; Drug Combinations; Humans; Otitis Media; Sulfamethoxazo | 1989 |
Experimental animal models for studying antimicrobial pharmacokinetics in otitis media.
Topics: Amoxicillin; Animals; Anti-Infective Agents; Chinchilla; Disease Models, Animal; Ear, Middle; Eustac | 1989 |
Comments on otitis media.
Topics: Anti-Infective Agents; Cefaclor; Colistin; Drug Combinations; Drug Resistance, Microbial; Humans; In | 1989 |
High-performance liquid chromatographic analysis of trimethoprim and sulfamethoxazole in microliter volumes of chinchilla middle ear effusion and serum.
Topics: Animals; Chinchilla; Chromatography, High Pressure Liquid; Otitis Media; Spectrophotometry, Ultravio | 1988 |
[Diagnostic and therapeutic protocol in otitis media in the 1st year of life].
Topics: Acute Disease; Age Factors; Amoxicillin; Drug Combinations; Humans; Infant; Infant, Newborn; Middle | 1988 |
Therapy of acute otitis media caused by Branhamella catarrhalis. Preliminary report.
Topics: Amoxicillin; Clavulanic Acid; Clavulanic Acids; Drug Combinations; Humans; Neisseriaceae; Otitis Med | 1986 |
Trimet v amoxycillin in the treatment of otitis media in children.
Topics: Acute Disease; Amoxicillin; Child; Child, Preschool; Drug Combinations; Humans; Otitis Media; Sulfan | 1985 |
Developments in diagnosing and treating otitis media.
Topics: Anti-Bacterial Agents; Bacterial Vaccines; Child; Child, Preschool; Drug Combinations; Hearing Disor | 1985 |
Trimethoprim-sulfamethoxazole: absorption, excretion, and toxicity in six children.
Topics: Agranulocytosis; Bacterial Infections; Carrier State; Child; Dose-Response Relationship, Drug; Drug | 1973 |
[Effect of Septrin on blood tetrahydrofolate concentration in children].
Topics: Age Factors; Child; Child, Preschool; Drug Combinations; Humans; Infant; Otitis Media; Sulfamethoxaz | 1973 |