Page last updated: 2024-11-05

trimethoprim and Liver Cirrhosis

trimethoprim has been researched along with Liver Cirrhosis in 5 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Liver Cirrhosis: Liver disease in which the normal microcirculation, the gross vascular anatomy, and the hepatic architecture have been variably destroyed and altered with fibrous septa surrounding regenerated or regenerating parenchymal nodules.

Research Excerpts

ExcerptRelevanceReference
"The extensive use of invasive procedures and of long-term norfloxacin prophylaxis in the management of cirrhotic patients may have influenced the epidemiology of bacterial infections in cirrhosis."7.71Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. ( Arroyo, V; Colmenero, J; Fernández, J; Gómez, J; Navasa, M; Rodés, J; Vila, J, 2002)
"The extensive use of invasive procedures and of long-term norfloxacin prophylaxis in the management of cirrhotic patients may have influenced the epidemiology of bacterial infections in cirrhosis."3.71Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis. ( Arroyo, V; Colmenero, J; Fernández, J; Gómez, J; Navasa, M; Rodés, J; Vila, J, 2002)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19904 (80.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Fernández, J1
Navasa, M1
Gómez, J1
Colmenero, J1
Vila, J1
Arroyo, V1
Rodés, J1
Quietzsch, J1
Siegert, E1
Günther, J1
Angelucci, L1
Baldieri, M1
Barba, C1
Lentini, S1
Linari, G1
Stocchi, F1
Destaing, F1
Villand, J1
Carli, H1
Carli, PM1
Martin, F1
Klepping, C1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Patterns of Antibiotic Resistant Bacterial Infections in Liver Intensive Care Unit[NCT03855709]200 participants (Anticipated)Observational2019-05-31Not yet recruiting
Comparison of 3 Days and 7 Days Intravenous Ceftriaxone Prophylaxis in Patients With Acute Variceal Bleeding[NCT00838864]Phase 479 participants (Actual)Interventional2009-03-31Completed
Comparison of Daily Norfloxacin Versus Weekly Ciprofloxacin for the Prevention of Spontaneous Bacterial Peritonitis in Cirrhotic Patients[NCT01542801]Phase 4124 participants (Actual)Interventional2011-08-31Completed
Rifaximin Versus Norfloxacin in the Primary Prophylaxis of Spontaneous Bacterial Peritonitis[NCT04159870]Phase 3322 participants (Anticipated)Interventional2019-11-05Active, not recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Other Studies

5 other studies available for trimethoprim and Liver Cirrhosis

ArticleYear
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
Bacterial infections in cirrhosis: epidemiological changes with invasive procedures and norfloxacin prophylaxis.
    Hepatology (Baltimore, Md.), 2002, Volume: 35, Issue:1

    Topics: Aged; Anti-Infective Agents; Bacterial Infections; Critical Care; Drug Resistance, Microbial; Escher

2002
[Multilobular biliary liver cirrhosis as a purely hepatic form of mucoviscidosis].
    Deutsche Zeitschrift fur Verdauungs- und Stoffwechselkrankheiten, 1979, Volume: 37, Issue:4

    Topics: Child; Cholangitis; Cholecystitis; Cystic Fibrosis; Drug Combinations; Humans; Liver Cirrhosis; Male

1979
[Plasma levels of cotrimoxazole in patients with hepatic insufficiency].
    La Clinica terapeutica, 1977, Apr-30, Volume: 81, Issue:2

    Topics: Aged; Biotransformation; Bronchitis; Drug Combinations; Female; Humans; Liver Cirrhosis; Male; Middl

1977
[Transient agranulocytosis in the course of treatment with sulfamethoxazole-trimethoprim].
    Annales de medecine interne, 1972, Volume: 123, Issue:2

    Topics: Adolescent; Adult; Aged; Agranulocytosis; Anemia, Hemolytic; Anti-Infective Agents; Bone Marrow; Bon

1972
[Clinical study of a new nonfungal antibiotic: the trimethoprim-sulfamethoxazole combination in gastroenterology].
    Revue medico-chirurgicale des maladies du foie, 1971, Volume: 46, Issue:6

    Topics: Adult; Aged; Anti-Infective Agents; Biliary Tract Diseases; Female; Folic Acid Antagonists; Humans;

1971