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trimethoprim and Lipodystrophy, Intestinal

trimethoprim has been researched along with Lipodystrophy, Intestinal in 20 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Research Excerpts

ExcerptRelevanceReference
"Treatment with trimethoprim-sulfamethoxazole resulted in rapid elimination of Whipple's bacilli from the jejunum and complete reversal of the patient's dementia over a 6-mo period."5.27Reversal of dementia associated with Whipple's disease by trimethoprim-sulfamethoxazole, drugs that penetrate the blood-brain barrier. ( Dobbins, WO; Eng, SC; Locksley, RM; Rubin, CE; Ryser, RJ; Schoenknecht, FD, 1984)
"Whipple's disease is a chronic, multisystemic, curable, bacterial infection that usually affects middle-aged men."2.45[Whipple's disease]. ( Puéchal, X, 2009)
"Whipple's disease is a systemic bacterial infection that once was uniformly fatal and now is treatable with several different antibiotics in most cases."2.37Whipple's disease. ( Feldman, M, 1986)
"Whipple's disease is a rare, chronic infection caused by Tropheryma whipplei, an ubiquitary gram positive bacterium."1.37[Of bugs and joints. Oligoarthritis caused by Tropheryma whipplei]. ( Battegay, M; Benz, D; Bloemberg, GV; Koligi, K; Mertz, D; Tyndall, A; Vogt, T; Walker, UA; Winter, L, 2011)
"To our knowledge, cerebellar ataxia in WD has never been formally studied in any large series."1.33Cerebellar ataxia and central nervous system whipple disease. ( Aksamit, AJ; Jones, LK; Josephs, KA; Matthews, BR; Saad, DA, 2005)
"Whipple's disease is a rare systemic illness, with the main clinical feature being severe malabsorption syndrome."1.29Case report: reversal of decreased bone mass by antibiotic treatment in a patient with Whipple's disease. ( Carnevale, V; Iannoni, C; Marcheggiano, A; Mazzuoli, G; Minisola, S; Romagnoli, E; Rosso, R, 1996)
"Treatment with trimethoprim-sulfamethoxazole resulted in rapid elimination of Whipple's bacilli from the jejunum and complete reversal of the patient's dementia over a 6-mo period."1.27Reversal of dementia associated with Whipple's disease by trimethoprim-sulfamethoxazole, drugs that penetrate the blood-brain barrier. ( Dobbins, WO; Eng, SC; Locksley, RM; Rubin, CE; Ryser, RJ; Schoenknecht, FD, 1984)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19909 (45.00)18.7374
1990's3 (15.00)18.2507
2000's4 (20.00)29.6817
2010's3 (15.00)24.3611
2020's1 (5.00)2.80

Authors

AuthorsStudies
Ioannou, P1
Kourtidis, M1
Mytilinis, DO1
Psyllaki, A1
Baliou, S1
Kofteridis, D1
Fenollar, F2
Perreal, C1
Raoult, D2
Puéchal, X1
Karsan, SS1
Karsan, HA1
Karsan, AS1
McMillen, JI1
Koligi, K1
Mertz, D1
Benz, D1
Vogt, T1
Bloemberg, GV1
Winter, L1
Tyndall, A1
Battegay, M1
Walker, UA1
Matthews, BR1
Jones, LK1
Saad, DA1
Aksamit, AJ1
Josephs, KA1
Revilla, FJ1
de la Cruz, R1
Khardori, N1
Espay, AJ1
Viteri, AL1
Greene, JF1
Chandler, JB1
Ryser, RJ1
Locksley, RM1
Eng, SC1
Dobbins, WO1
Schoenknecht, FD1
Rubin, CE1
Tyor, MP1
Simpson, DA1
Wishnow, R1
Gargulinski, RB1
Pawlak, AM1
Carnevale, V1
Minisola, S1
Romagnoli, E1
Rosso, R1
Marcheggiano, A1
Iannoni, C1
Mazzuoli, G1
Haeney, MR1
Ross, IN1
Tauris, P1
Moesner, J1
Morrison, DA1
Gay, RG1
Feldshon, D1
Sampliner, RE1
Feldman, M1
McKinley, R1
Grace, CS1
González, M1
Palma, R1
Smok, G1
Gallo, G1
Lecannelier, E1
Kortsik, CS1
Heine, M1
Staedt, U1
Kirschstein, W1
Gladisch, R1

Reviews

5 reviews available for trimethoprim and Lipodystrophy, Intestinal

ArticleYear
Whipple's disease-associated infective endocarditis: a systematic review.
    Infectious diseases (London, England), 2023, Volume: 55, Issue:7

    Topics: Anti-Bacterial Agents; Endocarditis, Bacterial; Humans; Sepsis; Sulfamethoxazole; Trimethoprim; Whip

2023
[Whipple's disease].
    La Revue de medecine interne, 2009, Volume: 30, Issue:3

    Topics: Administration, Oral; Adolescent; Adult; Age Factors; Aged; Anti-Bacterial Agents; Anti-Infective Ag

2009
Whipple's disease. The Duke connection.
    North Carolina medical journal, 1994, Volume: 55, Issue:6

    Topics: Biopsy; Duodenum; Humans; Intestinal Mucosa; Jejunum; Macrophages; Mesentery; Microscopy, Electron;

1994
Oculofacial-skeletal myorhythmia in central nervous system Whipple's disease: additional case and review of the literature.
    Movement disorders : official journal of the Movement Disorder Society, 1995, Volume: 10, Issue:2

    Topics: Adult; Ceftriaxone; Follow-Up Studies; Humans; Male; Movement Disorders; Oculomotor Muscles; Sulfame

1995
Whipple's disease.
    The American journal of the medical sciences, 1986, Volume: 291, Issue:1

    Topics: Bacterial Infections; Diagnosis, Differential; Drug Combinations; Eye Diseases; Heart Diseases; Hema

1986

Other Studies

15 other studies available for trimethoprim and Lipodystrophy, Intestinal

ArticleYear
Tropheryma whipplei natural resistance to trimethoprim and sulphonamides in vitro.
    International journal of antimicrobial agents, 2014, Volume: 43, Issue:4

    Topics: Drug Resistance, Multiple, Bacterial; Humans; Microbial Sensitivity Tests; Sulfadiazine; Trimethopri

2014
A case of Noonan syndrome and Whipple's disease in the same patient.
    World journal of gastroenterology, 2009, Mar-28, Volume: 15, Issue:12

    Topics: Adult; Anti-Infective Agents; Biopsy; Female; Humans; Macrophages; Noonan Syndrome; Sulfamethoxazole

2009
Infection: How should classic Whipple disease be managed?
    Nature reviews. Gastroenterology & hepatology, 2010, Volume: 7, Issue:5

    Topics: Administration, Oral; Anti-Bacterial Agents; Anti-Infective Agents; Antimalarials; Ceftriaxone; Drug

2010
[Of bugs and joints. Oligoarthritis caused by Tropheryma whipplei].
    Der Internist, 2011, Volume: 52, Issue:7

    Topics: Administration, Oral; Aged; Anti-Bacterial Agents; Arthritis, Infectious; Arthroscopy; Ceftriaxone;

2011
Cerebellar ataxia and central nervous system whipple disease.
    Archives of neurology, 2005, Volume: 62, Issue:4

    Topics: Adult; Age of Onset; Aged; Ceftriaxone; Cerebellar Ataxia; Cerebellum; Comorbidity; Drug Therapy, Co

2005
Teaching NeuroImage: Oculomasticatory myorhythmia: pathognomonic phenomenology of Whipple disease.
    Neurology, 2008, Feb-05, Volume: 70, Issue:6

    Topics: Adult; Anti-Infective Agents; Anti-Infective Agents, Urinary; DNA, Bacterial; Facial Muscles; Humans

2008
Whipple's disease, successful response to sulfamethoxazole-trimethoprim.
    The American journal of gastroenterology, 1981, Volume: 75, Issue:4

    Topics: Drug Combinations; Follow-Up Studies; Humans; Male; Middle Aged; Sulfamethoxazole; Trimethoprim; Whi

1981
Reversal of dementia associated with Whipple's disease by trimethoprim-sulfamethoxazole, drugs that penetrate the blood-brain barrier.
    Gastroenterology, 1984, Volume: 86, Issue:4

    Topics: Aged; Biopsy; Blood-Brain Barrier; Dementia; Drug Therapy, Combination; Humans; Intestine, Small; Ma

1984
Case report: reversal of decreased bone mass by antibiotic treatment in a patient with Whipple's disease.
    The American journal of the medical sciences, 1996, Volume: 311, Issue:3

    Topics: Anti-Infective Agents; Bone Density; Humans; Male; Middle Aged; Osteoporosis; Sulfamethoxazole; Trim

1996
Whipple's disease in a female with impaired cell-mediated immunity unresponsive to co-trimoxazole and levamisole therapy.
    Postgraduate medical journal, 1978, Volume: 54, Issue:627

    Topics: Drug Combinations; Female; Humans; Immunity, Cellular; Intestines; Jejunum; Levamisole; Middle Aged;

1978
Whipple's disease. Clinical and histopathological changes during treatment with sulphamethoxazole-trimethoprim.
    Acta medica Scandinavica, 1978, Volume: 204, Issue:5

    Topics: Adult; Bone Marrow; Drug Combinations; Follow-Up Studies; Humans; Intestinal Mucosa; Jejunum; Male;

1978
Severe pulmonary hypertension in a patient with Whipple's disease.
    The American journal of medicine, 1985, Volume: 79, Issue:2

    Topics: Drug Combinations; Furosemide; Heart Failure; Heart Murmurs; Humans; Hypertension, Pulmonary; Male;

1985
Whipple's disease in an HLA-B27 positive female.
    Australian and New Zealand journal of medicine, 1985, Volume: 15, Issue:6

    Topics: Anti-Infective Agents; Arthritis; Biopsy; Chloramphenicol; Drug Combinations; Female; HLA Antigens;

1985
[Whipple's disease].
    Revista medica de Chile, 1987, Volume: 115, Issue:2

    Topics: Biopsy; Drug Combinations; Female; Humans; Intestinal Mucosa; Male; Middle Aged; Penicillins; Strept

1987
[Malignant tumor-like abdominal lymphoma in Whipple's disease].
    Deutsche medizinische Wochenschrift (1946), 1989, Jul-14, Volume: 114, Issue:28-29

    Topics: Abdominal Neoplasms; Adult; Diagnosis, Differential; Drug Therapy, Combination; Female; Humans; Lymp

1989