Page last updated: 2024-11-05

trimethoprim and Keratitis

trimethoprim has been researched along with Keratitis in 9 studies

Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.

Keratitis: Inflammation of the cornea.

Research Excerpts

ExcerptRelevanceReference
" A 3-month course of chronic keratitis with persistent epithelial defect resolved in 48 h following the use of topical trimethoprim-sulfamethoxazole."3.67Nocardia asteroides keratitis presenting as a persistent epithelial defect. ( Donnenfeld, ED; Nauheim, JS; Perry, HD, 1989)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19902 (22.22)18.7374
1990's1 (11.11)18.2507
2000's2 (22.22)29.6817
2010's3 (33.33)24.3611
2020's1 (11.11)2.80

Authors

AuthorsStudies
Mei, JA1
Johnson, W1
Kinn, B1
Laskey, E1
Nolin, L1
Bhamare, P1
Stalker, C1
Dunman, PM3
Wozniak, RAF3
Chojnacki, M2
Philbrick, A2
Wucher, B1
Reed, JN1
Tomaras, A1
Scherzi, T1
Pecora, N1
Kiernan, DF1
Chin, EK1
Sclafani, LA1
Saidel, MA1
Chuang, CC1
Hsiao, CH1
Tan, HY1
Ma, DH1
Lin, KK1
Chang, CJ1
Huang, YC1
Lee, LH1
Zaidman, GW1
Van Horn, K1
Bucci, FA1
Holland, EJ1
Perry, HD1
Nauheim, JS1
Donnenfeld, ED2
Cohen, EJ1
Barza, M1
Baum, J1

Other Studies

9 other studies available for trimethoprim and Keratitis

ArticleYear
Antimicrobial Activity of a Triple Antibiotic Combination Toward Ocular Pseudomonas aeruginosa Clinical Isolates.
    Translational vision science & technology, 2022, 05-02, Volume: 11, Issue:5

    Topics: Anti-Bacterial Agents; Bacitracin; Drug Combinations; Erythromycin; Framycetin; Humans; Keratitis; L

2022
Development of a Broad-Spectrum Antimicrobial Combination for the Treatment of Staphylococcus aureus and Pseudomonas aeruginosa Corneal Infections.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Cornea; Disease Models, Animal; Drug Resistance, Multiple, Bacterial

2019
A Novel, Broad-Spectrum Antimicrobial Combination for the Treatment of Pseudomonas aeruginosa Corneal Infections.
    Antimicrobial agents and chemotherapy, 2019, Volume: 63, Issue:10

    Topics: Animals; Anti-Bacterial Agents; Cornea; Drug Resistance, Multiple, Bacterial; Drug Therapy, Combinat

2019
Multiple drug-resistant Alcaligenes xylosoxidans keratitis in a sanitation worker.
    Eye & contact lens, 2009, Volume: 35, Issue:4

    Topics: Achromobacter denitrificans; Administration, Topical; Adult; Aminoglycosides; Anti-Bacterial Agents;

2009
Staphylococcus aureus ocular infection: methicillin-resistance, clinical features, and antibiotic susceptibilities.
    PloS one, 2012, Volume: 8, Issue:8

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Clindamycin; Erythromycin; Female; Humans; Keratitis; Male

2012
Topical bactrim versus trimethoprim and sulfonamide against nocardia keratitis.
    Cornea, 2001, Volume: 20, Issue:2

    Topics: Administration, Topical; Adult; Anti-Infective Agents, Local; Cornea; Eye Infections, Bacterial; Hum

2001
Flavobacterium meningosepticum keratitis successfully treated with topical trimethoprim-sulfamethoxazole.
    American journal of ophthalmology, 1991, Jan-15, Volume: 111, Issue:1

    Topics: Administration, Topical; Aged; Aged, 80 and over; Corneal Transplantation; Eye Infections, Bacterial

1991
Nocardia asteroides keratitis presenting as a persistent epithelial defect.
    Cornea, 1989, Volume: 8, Issue:1

    Topics: Aged; Bacteriological Techniques; Cornea; Drug Combinations; Epithelium; Humans; Infusions, Intraven

1989
Treatment of Nocardia keratitis with topical trimethoprim-sulfamethoxazole.
    American journal of ophthalmology, 1985, May-15, Volume: 99, Issue:5

    Topics: Adult; Drug Combinations; Humans; Keratitis; Male; Nocardia Infections; Sulfamethoxazole; Trimethopr

1985