trimethoprim has been researched along with Injuries, Spinal Cord in 7 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Lidaprim, a bactericidal chemotherapeutical substance (combination of sulfametrol and trimethoprim), was administered to 29 patients with transverse lesions of the cord with paraplegia and urinary tract infections." | 9.05 | [Treatment of urinary tract infections in paralytics with spinal cord lesions. Effect and tolerance of co-soltrim (lidaprim)]. ( Kahle, D; Kisten, P, 1981) |
| "Lidaprim, a bactericidal chemotherapeutical substance (combination of sulfametrol and trimethoprim), was administered to 29 patients with transverse lesions of the cord with paraplegia and urinary tract infections." | 5.05 | [Treatment of urinary tract infections in paralytics with spinal cord lesions. Effect and tolerance of co-soltrim (lidaprim)]. ( Kahle, D; Kisten, P, 1981) |
| "We conducted 202 trials in 161 male hospital patients to determine if prophylactic administration of ascorbic acid or antibacterials (trimethoprim-sulfamethoxazole, nalidixic acid, methenamine hippurate or nitrofurantoin macrocrystals) would prevent bacteriuria infections in spinal cord injury patients who had had at least 1 bout of bacteriuria." | 5.05 | Prophylactic antibacterial therapy for preventing urinary tract infections in spinal cord injury patients. ( Kuhlemeier, KV; Lloyd, LK; Stover, SL, 1985) |
| "Antibiotic-associated colitis (pseudomembranous colitis) developed in four patients with spinal cord injury and taking oral trimethoprim-sulfamethoxazole." | 3.67 | Trimethoprim-sulfamethoxazole, pseudomembranous colitis, and spinal cord injury. ( Sugarman, B, 1985) |
| " These results suggest that the long-term use of antimicrobial suppressants can help reduce rates of urinary tract infection in bladder-retrained patients and in patients emptying by intermittent self-catheterization." | 1.26 | Bacteriuria during follow-up in patients with spinal cord injury: II Efficacy of antimicrobial suppressants. ( Erickson, RP; Merritt, JL; Opitz, JL, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maynard, FM | 1 |
| Diokno, AC | 1 |
| Perkash, A | 1 |
| Merritt, JL | 1 |
| Erickson, RP | 1 |
| Opitz, JL | 1 |
| Kisten, P | 1 |
| Kahle, D | 1 |
| Arego, DE | 1 |
| Koch, SJ | 1 |
| Sugarman, B | 1 |
| Kuhlemeier, KV | 1 |
| Stover, SL | 1 |
| Lloyd, LK | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Post-operative Voiding Dysfunction: the Preferred Method for Catheterization[NCT01597544] | 150 participants (Anticipated) | Interventional | 2012-07-31 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for trimethoprim and Injuries, Spinal Cord
| Article | Year |
|---|---|
[Treatment of urinary tract infections in paralytics with spinal cord lesions. Effect and tolerance of co-soltrim (lidaprim)].
Topics: Anti-Bacterial Agents; Bacterial Infections; Bacteriuria; Drug Administration Schedule; Drug Combina | 1981 |
Prophylactic antibacterial therapy for preventing urinary tract infections in spinal cord injury patients.
Topics: Anti-Infective Agents, Urinary; Ascorbic Acid; Bacteriuria; Clinical Trials as Topic; Drug Combinati | 1985 |
5 other studies available for trimethoprim and Injuries, Spinal Cord
| Article | Year |
|---|---|
Urinary infection and complications during clean intermittent catheterization following spinal cord injury.
Topics: Anti-Infective Agents, Urinary; Bacteriuria; Drug Combinations; Female; Hospitalization; Humans; Mal | 1984 |
Experience with the management of deep vein thrombosis in patients with spinal cord injury. Part II: a critical evaluation of the anticoagulant therapy.
Topics: Administration, Oral; Adult; Anticoagulants; Drug Combinations; Drug Interactions; Hematuria; Hepari | 1980 |
Bacteriuria during follow-up in patients with spinal cord injury: II Efficacy of antimicrobial suppressants.
Topics: Anti-Infective Agents, Urinary; Bacteriuria; Follow-Up Studies; Humans; Methenamine; Spinal Cord Inj | 1982 |
Bacteriuria in patients with spinal cord injury.
Topics: Aminoglycosides; Bacteriuria; Catheters, Indwelling; Cephalosporins; Drug Combinations; Humans; Male | 1986 |
Trimethoprim-sulfamethoxazole, pseudomembranous colitis, and spinal cord injury.
Topics: Adult; Anti-Infective Agents, Urinary; Clostridium Infections; Diarrhea; Drug Combinations; Enteroco | 1985 |