trimethoprim has been researched along with Infections, Proteus in 40 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Trimethoprim, in combination with sulfadiazine or sulfamethoxazole was administered orally for 7 to 14 days to 84 dogs with urinary tract infections (UTI)." | 7.66 | Trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections. ( Ling, GV; Ruby, AL, 1979) |
| "Acute lower urinary tract infections were treated in 57 women according to a randomized protocol, using either cefaclor, a cephalosporin whose chemical structure is similar to that of cephalexin, or trimethoprim-sulfamethoxazole combination." | 5.05 | A comparison of cefaclor versus trimethoprim-sulfamethoxazole combination in the treatment of acute urinary infections. ( Rous, SN, 1981) |
| "Ninety patients with urinary tract infections were treated in a randomized double-blind study with either a combination of trimethoprim and sulfamethoxazole (TMP-SMX) or sulfamethoxazole alone (SMX)." | 5.04 | A comparison of trimethorprim-sulfamethoxazole with sulfamethoxazole alone in infections localized to the kidneys. ( Boutros, P; Harding, GK; Lank, B; Ronald, AR, 1975) |
| "A prospective double-blind study was performed in which 30 adult patients with recurrent urinary tract infections due to Escherichia coli, and Proteus mirabilis organisms were treated by twenty-eight-day courses of either ampicillin, 500 mg." | 5.04 | Twenty-eight-day courses of antibiotics for urinary tract infection. ( Cosgrove, MD; Fiorentino, N; Gault, C; Ivler, D, 1976) |
| "Trimethoprim, in combination with sulfadiazine or sulfamethoxazole was administered orally for 7 to 14 days to 84 dogs with urinary tract infections (UTI)." | 3.66 | Trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections. ( Ling, GV; Ruby, AL, 1979) |
| "Colonization of the vaginal introitus with Enterobacteriaceae was cleared dramatically in women receiving trimethoprim-sulfamethoxazole for recurrent urinary tract infections." | 3.65 | The diffusion and concentration of trimethoprim in human vaginal fluid. ( Condy, M; Stamey, TA, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 37 (92.50) | 18.7374 |
| 1990's | 2 (5.00) | 18.2507 |
| 2000's | 1 (2.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, M | 2 |
| Guo, Q | 1 |
| Xu, X | 1 |
| Wang, X | 1 |
| Ye, X | 1 |
| Wu, S | 1 |
| Hooper, DC | 1 |
| COOPER, RG | 1 |
| WALD, M | 1 |
| Blankenship, ML | 1 |
| Ling, GV | 2 |
| Rous, SN | 1 |
| Divers, TJ | 1 |
| Byars, TD | 1 |
| Murch, O | 1 |
| Sigel, CW | 1 |
| Wilson, C | 1 |
| Senior, BW | 1 |
| Tiwana, H | 1 |
| Caparros-Wanderley, W | 1 |
| Ebringer, A | 1 |
| Meares, EM | 2 |
| Wesolowski, S | 1 |
| Wencel, J | 1 |
| Czaplicki, M | 1 |
| Borkowski, A | 1 |
| Ruby, AL | 1 |
| Mathews, DD | 1 |
| Agarwal, V | 1 |
| Gordon, AM | 1 |
| Cooper, J | 1 |
| Brandberg, A | 2 |
| Darby, CP | 1 |
| Hill, O | 1 |
| Sabel, KG | 1 |
| Stamey, TA | 2 |
| Condy, M | 1 |
| Sher, N | 1 |
| Wong, CK | 1 |
| Harding, GK | 2 |
| Ronald, AR | 2 |
| Hoban, S | 1 |
| Boutros, P | 1 |
| Lank, B | 1 |
| Cosgrove, MD | 2 |
| Gault, C | 1 |
| Fiorentino, N | 1 |
| Ivler, D | 1 |
| Griffith-Jones, MD | 1 |
| Dubini, F | 1 |
| Riviera, L | 1 |
| Visconti, A | 1 |
| Räisänen, S | 1 |
| Ylitalo, P | 1 |
| Toponen, A | 1 |
| Seppänen, J | 1 |
| Ukhin, AV | 1 |
| Grunberg, E | 2 |
| Drach, GW | 1 |
| Schach, H | 1 |
| Scheidt, J | 1 |
| Neussel, H | 1 |
| Hitchings, GH | 1 |
| Forbes, PA | 1 |
| Drummond, KN | 1 |
| Gleckman, RA | 1 |
| Morrow, JW | 1 |
| Hoffer, M | 1 |
| Mitrovic, M | 1 |
| Brossi, A | 1 |
| Tauchnitz, C | 1 |
| Porpáczy, P | 1 |
| Dargie, HJ | 1 |
| Allison, ME | 1 |
| McGeachie, J | 1 |
| Macdonald, GA | 1 |
| Kennedy, AC | 1 |
| Gavras, H | 1 |
| Lawson, DH | 1 |
| Linton, AL | 1 |
| Chüden, HG | 1 |
| Lowbury, EJ | 1 |
| Jackson, DM | 1 |
| Ricketts, CR | 1 |
| Davis, B | 1 |
| Línek, I | 1 |
| Heller, J | 1 |
3 reviews available for trimethoprim and Infections, Proteus
| Article | Year |
|---|---|
Treatment of urinary tract infections.
Topics: Ampicillin; Animals; Dog Diseases; Dogs; Escherichia coli Infections; Penicillin G; Penicillin Resis | 1980 |
[Present status of the treatment of urological infections].
Topics: Amoxicillin; Ampicillin; Anti-Bacterial Agents; Anti-Infective Agents, Urinary; Cross Infection; Dru | 1985 |
The effect of trimethoprim on the activity of sulfonamides and antibiotics in experimental infections.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Synergism; Escheric | 1973 |
7 trials available for trimethoprim and Infections, Proteus
| Article | Year |
|---|---|
A comparison of cefaclor versus trimethoprim-sulfamethoxazole combination in the treatment of acute urinary infections.
Topics: Adolescent; Adult; Anti-Infective Agents, Urinary; Cefaclor; Cephalexin; Clinical Trials as Topic; D | 1981 |
A double-blind trial of single-dose chemoprophylaxis with co-trimoxazole during vaginal hysterectomy and repair.
Topics: Aged; Clinical Trials as Topic; Double-Blind Method; Drug Administration Schedule; Drug Combinations | 1979 |
Co-trimoxazole in cases of gram-negative septicaemia.
Topics: Adolescent; Adult; Aged; Bacteroides Infections; Clinical Trials as Topic; Drug Combinations; Drug E | 1976 |
A comparison of trimethorprim-sulfamethoxazole with sulfamethoxazole alone in infections localized to the kidneys.
Topics: Administration, Oral; Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Drug | 1975 |
Twenty-eight-day courses of antibiotics for urinary tract infection.
Topics: Adult; Aged; Ampicillin; Drug Administration Schedule; Drug Therapy, Combination; Escherichia coli I | 1976 |
[Results of treatment with trimethoprim-sulfamethoxazole in nonspecific urinary tract infections in pediatric urology].
Topics: Adolescent; Anti-Bacterial Agents; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topi | 1972 |
A cooperative controlled study of the use of trimethoprim-sulfamethoxazole in chronic urinary tract infections.
Topics: Chronic Disease; Clinical Trials as Topic; Drug Combinations; Enterobacteriaceae Infections; Escheri | 1973 |
30 other studies available for trimethoprim and Infections, Proteus
| Article | Year |
|---|---|
New plasmid-mediated quinolone resistance gene, qnrC, found in a clinical isolate of Proteus mirabilis.
Topics: Amino Acid Sequence; Anti-Infective Agents; Bacterial Proteins; Base Sequence; Conjugation, Genetic; | 2009 |
SUCCESSFUL TREATMENT OF PROTEUS SEPTICAEMIA WITH A NEW DRUG TRIMETHOPRIM.
Topics: Anti-Infective Agents; Drug Therapy; Polymyxins; Proteus; Proteus Infections; Pyrimidines; Sepsis; S | 1964 |
Gram-negative folliculitis. Follow-up observations in 20 patients.
Topics: Adolescent; Adult; Ampicillin; Bacterial Infections; Drug Combinations; Female; Folliculitis; Follow | 1984 |
Experimental induction of Proteus mirabilis cystitis in the pony and evaluation of therapy with trimethoprim-sulfadiazine.
Topics: Administration, Oral; Animals; Cystitis; Drug Combinations; Female; Horse Diseases; Horses; Nitrofur | 1981 |
Antibiotic sensitivity and proticine typing of Proteus mirabilis strains associated with rheumatoid arthritis.
Topics: Adult; Aged; Anti-Bacterial Agents; Anti-Infective Agents; Anti-Infective Agents, Urinary; Arthritis | 1998 |
Long-term therapy of chronic bacterial prostatitis with trimethoprim-sulfamethoxazole.
Topics: Acinetobacter Infections; Administration, Oral; Adult; Aged; Bacterial Infections; Body Fluids; Drug | 1975 |
Antibacterial prophylaxis in patients after prostatectomy.
Topics: Aged; Bacterial Infections; Chloramphenicol; Enterobacteriaceae Infections; Escherichia coli Infecti | 1977 |
Trimethoprim in combination with a sulfonamide for oral treatment of canine urinary tract infections.
Topics: Administration, Oral; Animals; Dog Diseases; Dogs; Drug Therapy, Combination; Escherichia coli Infec | 1979 |
Proteus morganii meningitis treated with trimethoprim-sulfamethoxazole (co-trimoxazole).
Topics: Ampicillin; Carbenicillin; Child, Preschool; Chloramphenicol; Drug Synergism; Dura Mater; Humans; Ka | 1975 |
Treatment of meningitis and septicemia in infancy with a sulphamethoxazole/trimethorpim combination.
Topics: Ampicillin; Anemia, Hypochromic; Body Weight; Drug Synergism; Drug Therapy, Combination; Escherichia | 1975 |
The diffusion and concentration of trimethoprim in human vaginal fluid.
Topics: Adult; Bacteriuria; Body Fluids; Diffusion; Dose-Response Relationship, Drug; Enterobacteriaceae; En | 1975 |
Prophylactic chemotherapy with low-dosage trimethoprim-sulfamethoxazole following acute urinary tract infections in children.
Topics: Ampicillin; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Drug Evaluation; Esche | 1975 |
Trimethoprim-resistant Enterobacteriaceae in urinary tract infection.
Topics: Drug Combinations; Drug Resistance, Microbial; Enterobacteriaceae Infections; Escherichia coli; Esch | 1975 |
Editorial: A clinical classification of urinary tract infections based upon origin.
Topics: Bacteriuria; Chronic Disease; Escherichia coli Infections; Female; Humans; Male; Methenamine; Nitrof | 1975 |
Disappearing staghorns.
Topics: Aged; Aged, 80 and over; Female; Humans; Kidney Calculi; Proteus Infections; Trimethoprim; Urinary T | 1990 |
[Experimental cystitis in the rat and the therapeutic effect of a single dose of fosfomycin trometamol].
Topics: Animals; Cystitis; Drug Combinations; Drug Evaluation, Preclinical; Escherichia coli Infections; Fos | 1987 |
Trimethoprim and methenamine hippurate. A new theoretical combination for the treatment of urinary tract infections.
Topics: Adult; Drug Resistance, Microbial; Drug Synergism; Drug Therapy, Combination; Escherichia coli Infec | 1985 |
Trimethoprim sulfamethoxazole therapy of chronic bacterial prostatitis.
Topics: Adolescent; Adult; Aged; Bacterial Infections; Candidiasis, Oral; Child; Drug Eruptions; Escherichia | 1974 |
Biochemical background of trimethoprim-sulphamethoxazole.
Topics: Aminobenzoates; Animals; Anti-Bacterial Agents; Bacteria; Drug Combinations; Drug Resistance, Microb | 1973 |
Trimethoprim-sulfamethoxazole in recurrent urinary tract infection in children.
Topics: Child; Enterobacteriaceae Infections; Escherichia coli Infections; Female; Humans; Male; Proteus Inf | 1973 |
Prostatitis. Observations on activity of trimethoprim-sulfamethoxazole in the prostate.
Topics: Adult; Bacterial Infections; Chronic Disease; Drug Combinations; Escherichia coli Infections; Humans | 1973 |
Ampicillin versus trimethoprim sulfamethoxazole in chronic urinary tract infection.
Topics: Adult; Aged; Ampicillin; Bacterial Infections; Chronic Disease; Enterobacteriaceae Infections; Esche | 1974 |
An improved synthesis of diaveridine, trimethoprim, and closely related 2,4-diaminopyrimidines.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Drug Synergism; Escherichia coli Infections; K | 1971 |
[Experiences with trimethoprim-sulfamethoxazole in the chemotherapy of bacterial infections].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Bacteriuria; Bronchiectasis; B | 1970 |
[Trimethoprim and sulfamethoxazole (Eusaprim) in chronic urinary tract infections].
Topics: Aged; Anti-Bacterial Agents; Chronic Disease; Escherichia coli; Escherichia coli Infections; Folic A | 1971 |
Long-term trimethoprim-sulphamethoxazole in the management of recurrent urinary infection.
Topics: Anti-Infective Agents; Drug Combinations; Escherichia coli Infections; Female; Folic Acid Antagonist | 1971 |
Extended therapy with a trimethoprim-sulphonamide for the treatment of established urinary tract infection.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Drug Combinations; Drug Hypersensitivity; Escherichi | 1971 |
[Indications for trimethoprim in otorhinolaryngology].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Bacterial Infections; Child; Drug Combinations; Drug | 1972 |
Topical chemoprophylaxis for burns: trials of creams containing silver sulphadiazine and trimethoprim.
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Burns; Child; Child, Preschool; Drug Resistance, Mic | 1971 |
[Therapy of urinary tract infections caused by Proteus strains].
Topics: Adult; Aged; Female; Humans; Male; Middle Aged; Nalidixic Acid; Proteus Infections; Sulfamethoxazole | 1971 |