trimethoprim has been researched along with Infection in 27 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-three profoundly granulocytopenic patients with relapsed acute leukemia who were undergoing reinduction chemotherapy were prospectively randomized to receive either trimethoprim-sulfamethoxazole plus nystatin or gentamicin plus nystatin for prevention of infections." | 9.05 | A comparison of trimethoprim-sulfamethoxazole plus nystatin with gentamicin plus nystatin in the prevention of infections in acute leukemia. ( Fortner, CL; Hargadon, MT; Schimpff, SC; Wade, JC; Wiernik, PH; Young, VM, 1981) |
| "Fifty-two patients with nonlymphocytic leukaemia were studied during remission induction treatment in a randomized trial to ascertain the effect of prophylactic oral trimethoprim-sulfamethoxazole on infection and fever rate." | 9.05 | Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia. ( Dekker, AW; Rozenberg-Arska, M; Sixma, JJ; Verhoef, J, 1981) |
| "Fifty-three profoundly granulocytopenic patients with relapsed acute leukemia who were undergoing reinduction chemotherapy were prospectively randomized to receive either trimethoprim-sulfamethoxazole plus nystatin or gentamicin plus nystatin for prevention of infections." | 5.05 | A comparison of trimethoprim-sulfamethoxazole plus nystatin with gentamicin plus nystatin in the prevention of infections in acute leukemia. ( Fortner, CL; Hargadon, MT; Schimpff, SC; Wade, JC; Wiernik, PH; Young, VM, 1981) |
| "Fifty-two patients with nonlymphocytic leukaemia were studied during remission induction treatment in a randomized trial to ascertain the effect of prophylactic oral trimethoprim-sulfamethoxazole on infection and fever rate." | 5.05 | Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia. ( Dekker, AW; Rozenberg-Arska, M; Sixma, JJ; Verhoef, J, 1981) |
| "In a previous acute lymphocytic leukemia (ALL) study of initial therapy, investigators were free to use TS prophylaxis or not." | 2.66 | Effect of trimethoprim/sulfamethoxazole prophylaxis on outcome of childhood lymphocytic leukemia. A Pediatric Oncology Group Study. ( Berry, DM; Crist, W; Doering, EJ; Fernbach, DJ; Pullen, J; Shuster, J; van Eys, J, 1987) |
| "In many neurosurgery-associated infections, intrathecal or intraventricular antibiotics may be required to supplement parenteral treatment and/or surgical intervention." | 2.36 | Antimicrobial agents and the central nervous system. ( Everett, ED; Strausbaugh, LJ, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 26 (96.30) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Peterson, PK | 1 |
| Simmons, RL | 1 |
| Romanet, P | 1 |
| Everett, ED | 1 |
| Strausbaugh, LJ | 1 |
| Weening, RS | 1 |
| Kabel, P | 1 |
| Pijman, P | 1 |
| Roos, D | 1 |
| Hendriks, WD | 1 |
| Sizoo, W | 1 |
| Löwenberg, B | 1 |
| Hagenbeek, A | 1 |
| Pizzo, PA | 1 |
| Wade, JC | 1 |
| Schimpff, SC | 1 |
| Hargadon, MT | 1 |
| Fortner, CL | 1 |
| Young, VM | 1 |
| Wiernik, PH | 1 |
| Dekker, AW | 1 |
| Rozenberg-Arska, M | 1 |
| Sixma, JJ | 1 |
| Verhoef, J | 1 |
| Scaglione, C | 1 |
| Tormena, AM | 1 |
| Pavlovsky, S | 1 |
| Gever, LN | 1 |
| Vasconcelles, MJ | 1 |
| Bernardo, MV | 1 |
| King, C | 1 |
| Weller, EA | 1 |
| Antin, JH | 1 |
| Jansen, W | 1 |
| Melikian, V | 1 |
| Falk, R | 1 |
| Collins, 2S | 1 |
| Brandesky, G | 1 |
| Takacs, F | 1 |
| Bertaggia, A | 1 |
| Forrest, CB | 1 |
| Forehand, JR | 1 |
| Axtell, RA | 1 |
| Roberts, RL | 1 |
| Johnston, RB | 1 |
| Davis, RE | 1 |
| Fox, GN | 1 |
| van Eys, J | 1 |
| Berry, DM | 1 |
| Crist, W | 1 |
| Doering, EJ | 1 |
| Fernbach, DJ | 1 |
| Pullen, J | 1 |
| Shuster, J | 1 |
| van der Waaij, D | 1 |
| Klastersky, J | 1 |
| Poskitt, EM | 1 |
| Garrod, LP | 1 |
| Israël, L | 1 |
| Hongre, JF | 1 |
| Farriaux, JP | 1 |
| Fontaine, G | 1 |
| Warot, P | 1 |
| Lambert, P | 1 |
3 reviews available for trimethoprim and Infection
| Article | Year |
|---|---|
Antimicrobial agents and the central nervous system.
Topics: Abscess; Anti-Bacterial Agents; Anti-Infective Agents; Central Nervous System Diseases; Cephalospori | 1980 |
[Bacteriologic management of patients with decreased resistance].
Topics: Agranulocytosis; Anti-Bacterial Agents; Antisepsis; Bacterial Infections; Drug Combinations; Humans; | 1984 |
Clinical chemistry of folic acid.
Topics: Absorption; Aged; Alcoholism; Anemia, Sickle Cell; Anticonvulsants; Arthritis, Rheumatoid; Biologica | 1986 |
5 trials available for trimethoprim and Infection
| Article | Year |
|---|---|
A comparison of trimethoprim-sulfamethoxazole plus nystatin with gentamicin plus nystatin in the prevention of infections in acute leukemia.
Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Drug Combinations; Drug Therapy, Combination; | 1981 |
Prevention of infection by trimethoprim-sulfamethoxazole plus amphotericin B in patients with acute nonlymphocytic leukaemia.
Topics: Acute Disease; Agranulocytosis; Amphotericin B; Drug Combinations; Drug Therapy, Combination; Fever; | 1981 |
[Prophylactic controlled trials with cotrimoxazole in afebrile neutropenic patients with malignant hemopathies].
Topics: Adult; Agranulocytosis; Child; Clinical Trials as Topic; Drug Combinations; Fever; Humans; Infection | 1982 |
Aerosolized pentamidine as pneumocystis prophylaxis after bone marrow transplantation is inferior to other regimens and is associated with decreased survival and an increased risk of other infections.
Topics: Administration, Inhalation; Adolescent; Adult; Aerosol Propellants; Aged; Antifungal Agents; Bone Ma | 2000 |
Effect of trimethoprim/sulfamethoxazole prophylaxis on outcome of childhood lymphocytic leukemia. A Pediatric Oncology Group Study.
Topics: Adult; Antineoplastic Combined Chemotherapy Protocols; Clinical Trials as Topic; Humans; Infections; | 1987 |
19 other studies available for trimethoprim and Infection
| Article | Year |
|---|---|
Infectious diseases in renal allograft recipients: new developments in therapy and prevention.
Topics: Acyclovir; Bacterial Infections; Cryptococcosis; Cytomegalovirus Infections; Drug Combinations; Huma | 1984 |
[Trial of pediatric quam in common ORL. infections in children].
Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Female; Humans; Infections; Male; Otorhinola | 1982 |
Continuous therapy with sulfamethoxazole-trimethoprim in patients with chronic granulomatous disease.
Topics: Adolescent; Adult; Child; Drug Therapy, Combination; Granulomatous Disease, Chronic; Humans; Infecti | 1983 |
Infectious complications in the child with cancer. III. Prevention.
Topics: Anti-Bacterial Agents; Child; Cross Infection; Filtration; Humans; Immunization; Immunization, Passi | 1981 |
Two antibiotics in one.
Topics: Drug Combinations; Drug Synergism; Humans; Infections; Sulfamethoxazole; Trimethoprim | 1980 |
[Experiences with Eusaprim suspension for adults in geriatric patients (author's transl)].
Topics: Age Factors; Aged; Cholecystitis; Drug Combinations; Drug Evaluation; Female; Gastroenteritis; Human | 1976 |
Treatment of febrile episodes in neutropenic patients.
Topics: Agranulocytosis; Anti-Bacterial Agents; Clindamycin; Drug Combinations; Fever; Humans; Immunosuppres | 1976 |
Co-trimoxazole.
Topics: Aged; Drug Combinations; Humans; Infections; Kidney; Kidney Diseases; Male; Sulfamethoxazole; Trimet | 1976 |
[Pharmacokinetic and chemical investigations in children after oral administration of lidaprim (author's transl)].
Topics: Child; Child, Preschool; Drug Combinations; Drug Tolerance; Humans; Infant; Infections; Sulfanilamid | 1975 |
[Parenteral (intravenous and intramuscular) administration of trimethoprim-sulfamethoxazole].
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Drug Tolerance; Female; Humans; Infections; Inject | 1975 |
Clinical features and current management of chronic granulomatous disease.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Drug Combinations; Drug The | 1988 |
Single-dose therapy for genitourinary infections.
Topics: Acute Disease; Anti-Bacterial Agents; Antifungal Agents; Candidiasis, Vulvovaginal; Cystitis; Drug A | 1987 |
[Limitations of selective decontamination of the digestive system in granulopenia patients toward the prevention of infection].
Topics: Agranulocytosis; Digestive System; Disinfection; Drug Combinations; Drug Resistance, Microbial; Huma | 1985 |
[Therapeutic use of antibiotic combinations].
Topics: Ampicillin; Anti-Bacterial Agents; Carbenicillin; Chloramphenicol; Colistin; Drug Combinations; Drug | 1971 |
Clinical problems related to the use of drugs in malnutrition.
Topics: Child; Child Nutritional Physiological Phenomena; Chloramphenicol; Chloroquine; Drug-Related Side Ef | 1974 |
[Therapy with trimethoprim-sulfamethoxazole].
Topics: Anti-Bacterial Agents; Brucellosis; Enterobacteriaceae; Enterobacteriaceae Infections; Folic Acid An | 1972 |
[Infections during antineoplastic drug therapy. Use of the sulfamethoxazole-trimethoprim association].
Topics: Anti-Infective Agents; Antineoplastic Agents; Drug Combinations; Drug Tolerance; Female; Folic Acid | 1972 |
[Value of Eusaprim suspension in pediatrics].
Topics: Adolescent; Anti-Infective Agents; Child; Child, Preschool; Female; Folic Acid Antagonists; Gastroen | 1971 |
[Study of the association of sulfamethoxazole and trimethoprim in surinfections in neurologic pathology].
Topics: Adolescent; Adult; Aged; Anti-Infective Agents; Cross Infection; Female; Folic Acid Antagonists; Hum | 1971 |