trimethoprim has been researched along with Infant, Newborn, Diseases in 14 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Infant, Newborn, Diseases: Diseases of newborn infants present at birth (congenital) or developing within the first month of birth. It does not include hereditary diseases not manifesting at birth or within the first 30 days of life nor does it include inborn errors of metabolism. Both HEREDITARY DISEASES and METABOLISM, INBORN ERRORS are available as general concepts.
| Excerpt | Relevance | Reference |
|---|---|---|
| "An infant with neonatal meningitis caused by Pseudomonas cepacia responded promptly to treatment with trimethoprim-sulfamethoxazole (Bactrim) after other abtibiotics had failed." | 7.65 | Treating Pseudomonas cepacia meningitis with trimethoprim-sulfamethoxazole. ( Darby, CP, 1976) |
| "Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media." | 7.65 | Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976) |
| "An infant with neonatal meningitis caused by Pseudomonas cepacia responded promptly to treatment with trimethoprim-sulfamethoxazole (Bactrim) after other abtibiotics had failed." | 3.65 | Treating Pseudomonas cepacia meningitis with trimethoprim-sulfamethoxazole. ( Darby, CP, 1976) |
| "Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media." | 3.65 | Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976) |
| "Treatment with trimethoprim-sulfamethoxazole was associated wtih rapid disappearance of circulating antigens; however, the small number of patients studied did not permit an analysis of its clinical efficacy." | 1.26 | Pneumocystis carinii pneumonitis in young immunocompetent infants. ( Brasfield, DM; Hughes, WT; Pifer, LL; Stagno, S; Tiller, RE, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 14 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Greene, GR | 1 |
| Heitlinger, L | 1 |
| Madden, JD | 1 |
| Stagno, S | 1 |
| Pifer, LL | 1 |
| Hughes, WT | 1 |
| Brasfield, DM | 1 |
| Tiller, RE | 1 |
| Lim, VK | 1 |
| Talib, S | 1 |
| Springer, C | 1 |
| Eyal, F | 1 |
| Michel, J | 1 |
| Rosenthal, E | 1 |
| Kohns, U | 1 |
| Paisley, JW | 1 |
| Washington, JA | 1 |
| Ansanelli, V | 1 |
| di Lena, C | 1 |
| Duggan, MB | 1 |
| Beyer, L | 1 |
| Santucci, S | 1 |
| Marazzini, P | 1 |
| Darby, CP | 1 |
| Shurin, PA | 1 |
| Pelton, SI | 1 |
| Scheifele, D | 1 |
| Klein, JO | 1 |
| Marosvári, I | 1 |
| McDonald, R | 1 |
| Lapage, SP | 1 |
| Owen, RJ | 1 |
1 trial available for trimethoprim and Infant, Newborn, Diseases
| Article | Year |
|---|---|
[Letter: Clinical pharmacological study of Sumetrolim].
Topics: Anti-Infective Agents; Clinical Trials as Topic; Drug Combinations; Drug Evaluation; Humans; Infant, | 1975 |
13 other studies available for trimethoprim and Infant, Newborn, Diseases
| Article | Year |
|---|---|
Citrobacter ventriculitis in a neonate responsive to trimethoprim-sulfamethoxazole.
Topics: Amikacin; Cerebral Ventricles; Citrobacter; Drug Combinations; Encephalitis; Enterobacteriaceae Infe | 1983 |
Pneumocystis carinii pneumonitis in young immunocompetent infants.
Topics: Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Pneumonia, Pneumocystis; S | 1980 |
A case of neonatal meningitis caused by Acinetobacter calcoaceticus var anitratus.
Topics: Acinetobacter Infections; Cross Infection; Drug Combinations; Female; Humans; Infant, Newborn; Infan | 1982 |
Pharmacology of trimethoprim-sulfamethoxazole in newborn infants.
Topics: Drug Therapy, Combination; Half-Life; Humans; Infant, Newborn; Infant, Newborn, Diseases; Injections | 1982 |
[An epidemic caused by serratia marcescens in an intensive-care unit for premature and other newborns (author's transl)].
Topics: Colistin; Cross Infection; Disease Outbreaks; Enterobacteriaceae Infections; Gentamicins; Germany, W | 1977 |
Susceptibility of Escherichia coli K1 to four combinations of antimicrobial agents potentially useful for treatment of neonatal meningitis.
Topics: Ampicillin; Anti-Bacterial Agents; Cefamandole; Cerebrospinal Fluid; Chloramphenicol; Drug Combinati | 1979 |
[Experiences of therapy of salmonellosis in newborn infants with chloramphenicol and cotrimoxazole].
Topics: Chloramphenicol; Drug Combinations; Drug Evaluation; Humans; Infant, Newborn; Infant, Newborn, Disea | 1979 |
Enteric fever in young Yoruba children.
Topics: Age Factors; Anemia; Arthritis, Infectious; Blood Transfusion; Child, Preschool; Chloramphenicol; Di | 1975 |
[1st experience with the use of cotrimoxazole in the combination drug therapy of neonatal meningitis].
Topics: Ampicillin; Drug Evaluation; Female; Gentamicins; Humans; Infant, Newborn; Infant, Newborn, Diseases | 1977 |
Treating Pseudomonas cepacia meningitis with trimethoprim-sulfamethoxazole.
Topics: Drug Combinations; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Meningitis; Pseudomon | 1976 |
Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae.
Topics: Ampicillin; Child, Preschool; Drug Combinations; Female; Haemophilus Infections; Haemophilus influen | 1976 |
Purulent meningitis in newborn babies: observations and comments based on a series of 82 patients.
Topics: Black People; Cerebral Ventricles; Escherichia coli; Female; Gentamicins; Humans; Hydrocephalus; Inf | 1972 |
Flavobacterium meningosepticum from cases of meningitis in Botswana and England.
Topics: Adult; Anemia, Aplastic; Anti-Bacterial Agents; Bangladesh; Botswana; England; Flavobacterium; Human | 1973 |