trimethoprim has been researched along with Haemophilus Infections in 43 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Haemophilus Infections: Infections with bacteria of the genus HAEMOPHILUS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection." | 9.04 | Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975) |
| "Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media." | 7.65 | Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976) |
| "The combination trimethoprim-sulfamethoxazole was given in high dosage (four tablets twice daily) for either 2 or 5 days to 20 patients with sinusitis diagnosed on clinical grounds." | 7.65 | Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis. ( Whitehead, E, 1975) |
| "Seventy-nine children with acute otitis media were the subjects in a study designed to compare the effectiveness of ampicillin and trimethoprim-sulfamethoxazole in this infection." | 5.04 | Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media. ( Cameron, GG; Johnston, MT; Pomahac, AC, 1975) |
| "Strains of Haemophilus influenzae, which did not belong to any of the known capsular serotypes and which were resistant in vitro to ampicillin, have been isolated from middle ear exudates of two children with otitis media." | 3.65 | Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae. ( Klein, JO; Pelton, SI; Scheifele, D; Shurin, PA, 1976) |
| "The combination trimethoprim-sulfamethoxazole was given in high dosage (four tablets twice daily) for either 2 or 5 days to 20 patients with sinusitis diagnosed on clinical grounds." | 3.65 | Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis. ( Whitehead, E, 1975) |
| " Rifampin in a daily dose of 20 mg/kg (maximum 600 mg) for 4 days eradicated the carrier state in 86% of cases, as did the combination of rifampin at the same dosage and trimethoprim in a daily dose of 5 mg/kg (maximum 160 mg) for 4 days." | 2.66 | Rifampin alone or with trimethoprim for contacts of children with Haemophilus influenzae type b infections. ( Bannatyne, RM; Cheung, R; Jadavji, T; Prober, CG, 1986) |
| "Trimethoprim was found in higher concentrations in the sputum than in the blood, although there were wide and significant variations in individual patient's sputum pharmacokinetic profiles." | 2.66 | Trimethoprim alone compared to co-trimoxazole in lower respiratory infections: pharmacokinetics and clinical effectiveness. ( Brumfitt, W; Hamilton-Miller, JM; Havard, CW; Tansley, H, 1985) |
| " The pharmacokinetic and residue elimination patterns of sulphachloropyridazine appear to be modified by disease, even without affecting key organs essential for drug metabolism." | 1.28 | Pharmacokinetic aspects of a sulphachloropyridazine trimethoprim preparation in normal and diseased fowl. ( Fuentes, V; Ocampo, L; Sumano, H, 1990) |
| "In 29 percent of the respiratory tract infections, H." | 1.26 | Hemophilus influenzae in hospitalized adults: current perspectives. ( Moellering, RC; Sherman, E; Simon, HB; Southwick, FS, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 38 (88.37) | 18.7374 |
| 1990's | 3 (6.98) | 18.2507 |
| 2000's | 1 (2.33) | 29.6817 |
| 2010's | 1 (2.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodríguez-Arce, I | 1 |
| Martí, S | 1 |
| Euba, B | 1 |
| Fernández-Calvet, A | 1 |
| Moleres, J | 1 |
| López-López, N | 1 |
| Barberán, M | 1 |
| Ramos-Vivas, J | 1 |
| Tubau, F | 1 |
| Losa, C | 1 |
| Ardanuy, C | 1 |
| Leiva, J | 1 |
| Yuste, JE | 1 |
| Garmendia, J | 1 |
| Manteca, A | 1 |
| Pelaez, AI | 1 |
| del Mar Garcia-Suarez, M | 1 |
| Hidalgo, E | 1 |
| del Busto, B | 1 |
| Mendez, FJ | 1 |
| Linster, N | 1 |
| Hinz, KH | 1 |
| Davies, AJ | 1 |
| Lewis, DA | 1 |
| Parker, RH | 1 |
| Daum, RS | 2 |
| Glode, MP | 2 |
| Ambrosino, D | 1 |
| Halsey, N | 1 |
| Goldmann, DA | 1 |
| Mather, FJ | 1 |
| Russell, R | 1 |
| Kamon, J | 1 |
| Murray, M | 1 |
| Band, JD | 1 |
| Campos, J | 2 |
| Garcia-Tornel, S | 1 |
| Sanfeliu, I | 1 |
| Yogev, R | 3 |
| Simon, HB | 1 |
| Southwick, FS | 1 |
| Moellering, RC | 1 |
| Sherman, E | 1 |
| Thornsberry, C | 2 |
| McDougal, LK | 2 |
| Moxon, ER | 1 |
| Melick, C | 1 |
| Glogowski, W | 1 |
| Muñoz, AI | 1 |
| Leahey, AB | 1 |
| Jones, D | 1 |
| de Groot, R | 1 |
| Sluijter, M | 1 |
| de Bruyn, A | 1 |
| Goessens, WH | 1 |
| Smith, AL | 1 |
| Hermans, PW | 1 |
| Hamory, BH | 1 |
| Sande, MA | 1 |
| Sydnor, A | 1 |
| Seale, DL | 1 |
| Gwaltney, JM | 1 |
| Malmvall, BE | 1 |
| Branefors-Helander, P | 1 |
| Joly, J | 1 |
| Ninane, G | 1 |
| Kraytman, M | 1 |
| Golberg, R | 1 |
| Washington, JA | 1 |
| Ardati, KO | 1 |
| Thirumoorthi, MC | 1 |
| Dajani, AS | 1 |
| Brandberg, A | 1 |
| Shurin, PA | 1 |
| Pelton, SI | 1 |
| Scheifele, D | 1 |
| Klein, JO | 1 |
| Cameron, GG | 1 |
| Pomahac, AC | 1 |
| Johnston, MT | 1 |
| Whitehead, E | 1 |
| Sumano, H | 1 |
| Fuentes, V | 1 |
| Ocampo, L | 1 |
| Lohr, JA | 1 |
| Austin, RD | 1 |
| Grossman, M | 1 |
| Hayden, GF | 1 |
| Knowlton, GM | 1 |
| Dudley, SM | 1 |
| Powell, M | 1 |
| Koutsia-Carouzou, C | 1 |
| Voutsinas, D | 1 |
| Seymour, A | 1 |
| Williams, JD | 1 |
| Kumar, A | 1 |
| Kelly, KJ | 1 |
| Fox, GN | 1 |
| Zamotaev, IP | 1 |
| Sokolova, VI | 1 |
| Makarenkova, RV | 1 |
| Marks, MI | 1 |
| Jadavji, T | 1 |
| Cheung, R | 1 |
| Bannatyne, RM | 1 |
| Prober, CG | 1 |
| Brumfitt, W | 1 |
| Hamilton-Miller, JM | 1 |
| Havard, CW | 1 |
| Tansley, H | 1 |
| Reece, RL | 1 |
| Coloe, PJ | 1 |
| Grunberg, E | 1 |
| Quick, CA | 1 |
| Wagner, D | 1 |
| May, JR | 1 |
| Davies, J | 1 |
| Hughes, DT | 1 |
| Bridger, RC | 1 |
| Gordon, A | 1 |
| Amies, CR | 1 |
3 reviews available for trimethoprim and Haemophilus Infections
| Article | Year |
|---|---|
Hemophilus influenzae infections: a brief review.
Topics: Ampicillin; Antigens, Bacterial; Child; Child, Preschool; Chloramphenicol; Haemophilus Infections; H | 1980 |
New applications of old antimicrobials.
Topics: Anti-Bacterial Agents; Bacterial Infections; Child; Chloramphenicol; Drug Combinations; Haemophilus | 1986 |
The effect of trimethoprim on the activity of sulfonamides and antibiotics in experimental infections.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacterial Infections; Drug Synergism; Escheric | 1973 |
10 trials available for trimethoprim and Haemophilus Infections
| Article | Year |
|---|---|
Trimethoprim and rifampin in combination for chemoprophylaxis of household contacts of patients with invasive infections due to Haemophilus influenzae type b.
Topics: Carrier State; Haemophilus Infections; Haemophilus influenzae; Humans; Microbial Sensitivity Tests; | 1983 |
Rifampin prophylaxis against H. flu type b spread - is it valid?
Topics: Adolescent; Adult; Carrier State; Cellulitis; Child; Child, Preschool; Clinical Trials as Topic; Dou | 1982 |
A double-blind comparative study of ampicillin, co-trimoxazole and josamycin in anthraco-silicotic miners, assessed by transtracheal puncture.
Topics: Ampicillin; Anthracosilicosis; Anti-Bacterial Agents; Bacterial Infections; Bronchitis; Clinical Tri | 1977 |
Co-trimoxazole in cases of gram-negative septicaemia.
Topics: Adolescent; Adult; Aged; Bacteroides Infections; Clinical Trials as Topic; Drug Combinations; Drug E | 1976 |
Comparative efficacy of ampicillin and trimethoprim-sulfamethoxazole in otitis media.
Topics: Administration, Oral; Ampicillin; Bacterial Infections; Body Weight; Child; Clinical Trials as Topic | 1975 |
Comparison of three topical antimicrobials for acute bacterial conjunctivitis.
Topics: Administration, Topical; Adolescent; Adult; Child; Child, Preschool; Conjunctivitis, Bacterial; Drug | 1988 |
[Therapeutic activity of Oriprim in bronchopulmonary diseases].
Topics: Administration, Oral; Bacterial Infections; Bronchitis; Clinical Trials as Topic; Drug Combinations; | 1986 |
Rifampin alone or with trimethoprim for contacts of children with Haemophilus influenzae type b infections.
Topics: Adult; Child; Child, Preschool; Clinical Trials as Topic; Drug Synergism; Drug Therapy, Combination; | 1986 |
Trimethoprim alone compared to co-trimoxazole in lower respiratory infections: pharmacokinetics and clinical effectiveness.
Topics: Adolescent; Adult; Aged; Drug Combinations; Female; Haemophilus Infections; Haemophilus influenzae; | 1985 |
Trimethoprim-sulfamethoxazole in the treatment of infections of the ears, nose, and throat.
Topics: Acute Disease; Bacterial Infections; Chronic Disease; Clinical Trials as Topic; Haemophilus Infectio | 1973 |
30 other studies available for trimethoprim and Haemophilus Infections
| Article | Year |
|---|---|
Inactivation of the Thymidylate Synthase
Topics: A549 Cells; Animals; Anti-Bacterial Agents; Bacterial Proteins; Cell Line, Tumor; DNA, Bacterial; Dr | 2017 |
A rare case of lung coinfection by Streptomyces cinereoruber and Haemophilus influenzae in a patient with severe chronic obstructive pulmonary disease: characterization at species level using molecular techniques.
Topics: Aged; Anti-Bacterial Agents; Anti-Inflammatory Agents; Bacterial Typing Techniques; DNA, Bacterial; | 2008 |
[In vivo effectiveness of the sulfonamide sulfachlorpyridazine (SCP) and of the combination of sulfachlorpyridazine and trimethoprim (SCP + TMP) against Haemophilus paragallinarum].
Topics: Administration, Oral; Animals; Chickens; Dose-Response Relationship, Drug; Drug Therapy, Combination | 1983 |
Rifampicin in non-tuberculous infections.
Topics: Chlamydia Infections; Drug Resistance, Microbial; Drug Therapy, Combination; Haemophilus Infections; | 1984 |
Hemophilus influenzae respiratory infection in adults. 2. Treatment guidelines.
Topics: Adult; Ampicillin; Anti-Bacterial Agents; beta-Lactamases; Bronchitis; Drug Combinations; Haemophilu | 1983 |
Susceptibility studies of multiply resistant Haemophilus influenzae isolated from pediatric patients and contacts.
Topics: Adult; Anti-Bacterial Agents; Carrier State; Child; Drug Combinations; Drug Resistance, Microbial; H | 1984 |
Use of trimethoprim-sulfamethoxazole against Haemophilus influenzae.
Topics: Child; Drug Therapy, Combination; Haemophilus Infections; Haemophilus influenzae; Humans; Sulfametho | 1980 |
Hemophilus influenzae in hospitalized adults: current perspectives.
Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Cefamandole; Cross Infection; Drug Resistance, Micro | 1980 |
Ampicillin-resistant Haemophilus influenzae. 2. Therapeutic considerations.
Topics: Adult; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Child; Chloramphenicol; Drug Combinations; Ha | 1982 |
Elaboration of type b capsule by Haemophilus influenzae as a determinant of pathogenicity and impaired killing by trimethoprim-sulfamethoxazole.
Topics: Animals; Drug Combinations; Drug Resistance, Microbial; Drug Tolerance; Haemophilus Infections; Haem | 1982 |
In-vitro bactericidal synergism of rifampicin and trimethoprim and implications for treatment of carriers of Haemophilus influenzae.
Topics: Carrier State; Drug Synergism; Haemophilus Infections; Haemophilus influenzae; Humans; Kinetics; Mic | 1982 |
In vitro development of rifampin resistance in clinical isolates of Haemophilus influenzae type b.
Topics: Colony-Forming Units Assay; Drug Resistance, Microbial; Haemophilus Infections; Haemophilus influenz | 1982 |
Haemophilus influenzae central corneal ulcer associated with cosmetic lens wear.
Topics: Adult; Anti-Bacterial Agents; Ciprofloxacin; Contact Lenses; Cornea; Corneal Ulcer; Drug Therapy, Co | 1996 |
Genetic characterization of trimethoprim resistance in Haemophilus influenzae.
Topics: Amino Acid Sequence; Anti-Bacterial Agents; Base Sequence; Cloning, Molecular; Drug Resistance, Micr | 1996 |
Etiology and antimicrobial therapy of acute maxillary sinusitis.
Topics: Adult; Amoxicillin; Ampicillin; Anti-Bacterial Agents; Bacteria; Haemophilus Infections; Haemophilus | 1979 |
R-factor involvement in a local outbreak of ampicillin-resistant Haemophilus influenzae infections.
Topics: Adolescent; Ampicillin; Child; Child, Preschool; Disease Outbreaks; Epitopes; Haemophilus Infections | 1978 |
The taxonomy and antimicrobial susceptibility of Haemophilus species in clinical specimens.
Topics: Ampicillin; Anti-Bacterial Agents; Bacteriological Techniques; Cefamandole; Cephalothin; Chloramphen | 1978 |
Intravenous trimethoprim-sulfamethoxazole in the treatment of serious infections in children.
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Therapy, Combination; Escherichia co | 1979 |
Otitis media caused by non-typable, ampicillin-resistant strains of Haemophilus influenzae.
Topics: Ampicillin; Child, Preschool; Drug Combinations; Female; Haemophilus Infections; Haemophilus influen | 1976 |
Use of high-dosage trimethoprim-sulfamethoxazole in sinusitis.
Topics: Adolescent; Bacteria; Bacterial Infections; Drug Combinations; Drug Evaluation; Haemophilus Infectio | 1975 |
Pharmacokinetic aspects of a sulphachloropyridazine trimethoprim preparation in normal and diseased fowl.
Topics: Acetylation; Administration, Oral; Analysis of Variance; Animals; Chickens; Disease Outbreaks; Drug | 1990 |
Resistance of clinical isolates of Haemophilus influenzae in United Kingdom 1986.
Topics: Ampicillin; Ampicillin Resistance; Anti-Bacterial Agents; beta-Lactamases; Chloramphenicol; Chloramp | 1987 |
In vitro activity of cefixime (CL284635) and other antimicrobial agents against Haemophilus isolates from pediatric patients.
Topics: Anti-Bacterial Agents; Cefixime; Cefotaxime; Child; Drug Combinations; Haemophilus Infections; Haemo | 1988 |
Single-dose therapy for genitourinary infections.
Topics: Acute Disease; Anti-Bacterial Agents; Antifungal Agents; Candidiasis, Vulvovaginal; Cystitis; Drug A | 1987 |
The resistance to anti-microbial agents of bacteria isolated from pathological conditions of birds in Victoria, 1978 to 1983.
Topics: Animals; Anti-Bacterial Agents; Bird Diseases; Birds; Drug Resistance, Microbial; Escherichia coli I | 1985 |
Haemophilus influenzae apparently resistant to trimethoprim.
Topics: Animals; Anti-Bacterial Agents; Culture Media; Drug Resistance, Microbial; Folic Acid Antagonists; H | 1973 |
Use of combinations of trimethoprim and sulfamethoxazole in the treatment of chest infections.
Topics: Acute Disease; Adult; Aged; Ampicillin; Bacterial Infections; Blood Cell Count; Bronchiectasis; Bron | 1973 |
Haemophilus influenzae: the relationship to upper respiratory tract infection.
Topics: Adolescent; Adult; Age Factors; Aged; Ampicillin; Anti-Bacterial Agents; Carrier State; Child; Child | 1974 |
Haemophilus influenzae.
Topics: Adult; Ampicillin; Cephalosporins; Child; Child, Preschool; Chloramphenicol; Drug Combinations; Fema | 1974 |
Letter: Trimethoprim-sulfamethoxazole: in vitro sensitivity of 1000 clinical isolates.
Topics: Bacteria; Bacterial Infections; Drug Combinations; Haemophilus; Haemophilus Infections; Humans; In V | 1974 |