trimethoprim has been researched along with Granulomatous Disease, Chronic in 21 studies
Trimethoprim: A pyrimidine inhibitor of dihydrofolate reductase, it is an antibacterial related to PYRIMETHAMINE. It is potentiated by SULFONAMIDES and the TRIMETHOPRIM, SULFAMETHOXAZOLE DRUG COMBINATION is the form most often used. It is sometimes used alone as an antimalarial. TRIMETHOPRIM RESISTANCE has been reported.
trimethoprim : An aminopyrimidine antibiotic whose structure consists of pyrimidine 2,4-diamine and 1,2,3-trimethoxybenzene moieties linked by a methylene bridge.
Granulomatous Disease, Chronic: A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Actinomycosis is a chronic granulomatous condition that commonly manifests as cervicofacial, pulmonary, or abdominal disease, caused by slowly progressive infection with oral and gastrointestinal commensal Actinomyces species." | 1.35 | Actinomyces in chronic granulomatous disease: an emerging and unanticipated pathogen. ( Beovic, B; Blanche, S; Brousse, N; Galmiche, L; Güngör, T; Holland, SM; Kayal, S; Lopatin, U; Mahlaoui, N; Reichenbach, J; Seger, RA; Siler, U; Zbinden, R, 2009) |
| " The long-term use of trimethoprim-sulfamethoxazole and ketoconazole as a preventive therapy for infections has also been evaluated." | 1.28 | Incidence, severity, and prevention of infections in chronic granulomatous disease. ( Fischer, A; Griscelli, C; Mouy, R; Seger, R; Vilmer, E, 1989) |
| "The value of long-term prophylactic treatment of chronic granulomatous disease (CGD) in childhood cannot be established with certainty, as controlled studies are not available." | 1.27 | Antibacterial prophylaxis in chronic granulomatous disease. A case report. ( Berant, M; Mendelsohn, HB; Merzbach, D, 1983) |
| "The etiology, incidence and treatment of chronic granulomatous disease of infancy are discussed." | 1.26 | Urologic manifestations of chronic granulomatous disease of infancy. ( Middleton, RG; Young, AK, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (85.71) | 18.7374 |
| 1990's | 1 (4.76) | 18.2507 |
| 2000's | 1 (4.76) | 29.6817 |
| 2010's | 1 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Reichenbach, J | 1 |
| Lopatin, U | 1 |
| Mahlaoui, N | 1 |
| Beovic, B | 1 |
| Siler, U | 1 |
| Zbinden, R | 1 |
| Seger, RA | 5 |
| Galmiche, L | 1 |
| Brousse, N | 1 |
| Kayal, S | 1 |
| Güngör, T | 1 |
| Blanche, S | 1 |
| Holland, SM | 1 |
| Esfandbod, M | 1 |
| Kabootari, M | 1 |
| Weening, RS | 1 |
| Kabel, P | 1 |
| Pijman, P | 1 |
| Roos, D | 1 |
| Frayha, HH | 1 |
| Biggar, WD | 1 |
| Mendelsohn, HB | 1 |
| Berant, M | 1 |
| Merzbach, D | 1 |
| Jacobs, RF | 1 |
| Wilson, CB | 1 |
| Gmünder, FK | 2 |
| Baumgartner, S | 1 |
| Tiefenauer, LX | 1 |
| Young, AK | 1 |
| Middleton, RG | 1 |
| Pedersen, FK | 1 |
| Johansen, KS | 1 |
| Rosenkvist, J | 1 |
| Tygstrup, I | 1 |
| Valerius, NH | 1 |
| Kobayashi, Y | 1 |
| Amano, D | 1 |
| Ueda, K | 1 |
| Kagosaki, Y | 1 |
| Usui, T | 1 |
| Vilde, JL | 1 |
| Leport, C | 1 |
| Mouy, R | 1 |
| Fischer, A | 1 |
| Vilmer, E | 1 |
| Seger, R | 2 |
| Griscelli, C | 1 |
| Forrest, CB | 1 |
| Forehand, JR | 1 |
| Axtell, RA | 1 |
| Roberts, RL | 1 |
| Johnston, RB | 1 |
| Gonzalez, LA | 1 |
| Hill, HR | 1 |
| O'Neil, KM | 1 |
| Herman, JH | 1 |
| Modlin, JF | 1 |
| Moxon, ER | 1 |
| Winkelstein, JA | 1 |
| Megyeri, P | 1 |
| Endreffy, E | 1 |
| Chandra, RK | 1 |
| Puri, S | 1 |
| Hobeika, CA | 1 |
| Heneghan, WD | 1 |
| Young, LW | 1 |
| Fanconi, S | 1 |
| Gmür, J | 1 |
| Willi, U | 1 |
| Schaer, G | 1 |
| Spiess, H | 1 |
| Otto, R | 1 |
| Hitzig, WH | 2 |
| Kremens, B | 1 |
| von Voss, H | 1 |
| Wahn, V | 1 |
| Höger, PH | 1 |
| Schaad, UB | 1 |
2 reviews available for trimethoprim and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
[Antibiotherapy in chronic familial granulomatosis].
Topics: Amphotericin B; Anti-Bacterial Agents; Anti-Infective Agents; Bacterial Infections; Drug Combination | 1990 |
Advantages and disadvantages of antimicrobial prophylaxis in chronic granulomatous disease of childhood.
Topics: Anti-Bacterial Agents; Bacterial Infections; Child; Drug Combinations; Drug Resistance, Microbial; G | 1988 |
19 other studies available for trimethoprim and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
Actinomyces in chronic granulomatous disease: an emerging and unanticipated pathogen.
Topics: Actinomyces; Actinomycosis; Adolescent; Adult; Amoxicillin; Anti-Bacterial Agents; Azithromycin; Bon | 2009 |
Images in clinical medicine. Chronic granulomatous disease.
Topics: Anti-Infective Agents; Child; Drug Combinations; Granulomatous Disease, Chronic; Humans; Itraconazol | 2012 |
Continuous therapy with sulfamethoxazole-trimethoprim in patients with chronic granulomatous disease.
Topics: Adolescent; Adult; Child; Drug Therapy, Combination; Granulomatous Disease, Chronic; Humans; Infecti | 1983 |
Chronic granulomatous disease of childhood: a changing pattern?
Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Granulomatous Disease, Chronic; Humans; Infa | 1983 |
Antibacterial prophylaxis in chronic granulomatous disease. A case report.
Topics: Adolescent; Drug Combinations; Granulomatous Disease, Chronic; Humans; Male; Sulfamethoxazole; Time | 1983 |
Activity of antibiotics in chronic granulomatous disease leukocytes.
Topics: Anti-Bacterial Agents; Clindamycin; Granulomatous Disease, Chronic; Humans; Kinetics; Leukocytes; Ne | 1983 |
Chronic granulomatous disease: mode of action of sulfamethoxazole/trimethoprim.
Topics: Catalase; Drug Therapy, Combination; Granulocytes; Granulomatous Disease, Chronic; Humans; In Vitro | 1981 |
Chronic granulomatous disease: effect of sulfamethoxazole/trimethoprim on neutrophil microbicidal function.
Topics: Drug Therapy, Combination; Granulomatous Disease, Chronic; Humans; Neutrophils; Phagocytosis; Sulfam | 1981 |
Urologic manifestations of chronic granulomatous disease of infancy.
Topics: Child, Preschool; Cystitis; Drug Therapy, Combination; Granulomatous Disease, Chronic; Humans; Infan | 1980 |
Refractory Pneumocystis carinii infection in chronic granulomatous disease: successful treatment with granulocytes.
Topics: Blood Transfusion; Child; Drug Combinations; Female; Granulocytes; Granulomatous Disease, Chronic; H | 1979 |
Treatment of seven cases of chronic granulomatous disease with sulfamethoxazole-trimethoprim (SMX-TMP).
Topics: Bacterial Infections; Child; Child, Preschool; Granulomatous Disease, Chronic; Humans; Infant; Male; | 1978 |
Incidence, severity, and prevention of infections in chronic granulomatous disease.
Topics: Adolescent; Bacterial Infections; Child; Child, Preschool; Drug Combinations; Genetic Linkage; Granu | 1989 |
Clinical features and current management of chronic granulomatous disease.
Topics: Adolescent; Adult; Bone Marrow Transplantation; Child; Child, Preschool; Drug Combinations; Drug The | 1988 |
Pseudomonas cepacia: an emerging pathogen in chronic granulomatous disease.
Topics: Adolescent; Child; Child, Preschool; Drug Combinations; Granulomatous Disease, Chronic; Humans; Pneu | 1986 |
Improvement of defective bactericidal capacity of polymorphonuclear leukocytes by isoniazide in a case of chronic granulomatous disease.
Topics: Blood Bactericidal Activity; Drug Combinations; Granulomatous Disease, Chronic; Humans; Infant; Ison | 1986 |
Radiological case of the month. Chronic granulomatous disease.
Topics: Child; Combined Modality Therapy; Digestive System; Granulomatous Disease, Chronic; Humans; Male; Ra | 1986 |
Surgery and granulocyte transfusions for life-threatening infections in chronic granulomatous disease.
Topics: Amphotericin B; Blood Transfusion; Child; Drug Combinations; Flucytosine; Granulocytes; Granulomatou | 1985 |
[Progressive-septic granulomatosis: improved prognosis with early diagnosis and targeted therapy. Report of 5 cases].
Topics: Adult; Anti-Bacterial Agents; Antifungal Agents; Drug Therapy, Combination; Female; Granulocytes; Gr | 1985 |
Chronic granulomatous disease: uptake and intracellular activity of fosfomycin in granulocytes.
Topics: Adolescent; Adult; Anti-Bacterial Agents; Bacterial Infections; Biological Transport, Active; Chemot | 1985 |